Parameter | Time | Non-BCL group (n = 34) | BCL group (n = 35) | P Value | ||
---|---|---|---|---|---|---|
Mean ± SD | Range | Mean ± SD | Range | |||
OSDI (0—100) | Baseline | 35.34 ± 16.46 (n = 33) | 13.63, 75.00 | 37.16 ± 13.54 (n = 35) | 14.58, 70.00 | 0.469 |
1 week | 31.87 ± 13.02 (n = 33) | 2.77, 62.50 | 19.17 ± 14.96 (n = 35) | 0.00, 66.66 | 0.000*** | |
1 month | 36.42 ± 13.49 (n = 25) | 10.00, 65.00 | 20.97 ± 15.75 (n = 29) | 0.00, 59.09 | 0.000*** | |
Redness score | Baseline | 1.98 ± 0.67 (n = 29) | 0.90, 3.30 | 1.78 ± 0.55 (n = 28) | 0.70, 3.20 | 0.221 |
1 week | 2.46 ± 0. 64 (n = 29) | 1.30, 3.80 | 2.05 ± 0.63 (n = 32) | 1.20, 3.50 | 0.014* | |
1 month | 2.48 ± 0.81 (n = 23) | 1.10, 4.00 | 1.83 ± 0.54 (n = 28) | 1.00, 2.80 | 0.004* | |
TMH (mm) | Baseline | 0.20 ± 0.08 (n = 33) | 0.09, 0.53 | 0.21 ± 0.13 (n = 34) | 0.11, 0.90 | 0.518 |
1 week | 0.19 ± 0.06 (n = 33) | 0.05, 0.38 | 0.21 ± 0.07 (n = 35) | 0.10, 0.38 | 0.551 | |
1 month | 0.24 ± 0.16 (n = 26) | 0.10, 0.97 | 0.20 ± 0.08 (n = 29) | 0.07, 0.51 | 0.483 | |
Meibography score (0–6) | Baseline | 2.09 ± 1.07 (n = 33) | 0.00, 4.00 | 1.93 ± 1.09 (n = 29) | 0.00, 4.00 | 0.731 |
1 week | 2.09 ± 1.10 (n = 33) | 0.00, 4.00 | 1.66 ± 0.88 (n = 33) | 0.00, 3.00 | 0.166 | |
1 month | 2.15 ± 1.15 (n = 26) | 0.00, 4.00 | 1.71 ± 0.97 (n = 28) | 0.00, 3.00 | 0.221 | |
FL | Baseline | 1.52 ± 1.72 | 0.00, 5.00 | 1.57 ± 1.48 | 0.00, 5.00 | 0.782 |
1 week | 2.47 ± 1.74 (n = 34) | 0.00, 6.00 | 0.97 ± 1.17 | 0.00, 3.00 | 0.000*** | |
1 month | 2.52 ± 1.93 (n = 25) | 0.00, 5.00 | 0.86 ± 1.24 (n = 29) | 0.00, 4.00 | 0.001** | |
NIF-BUT(s) | Baseline | 4.30 ± 2.92 (n = 31) | 1.15, 15.29 | 4.93 ± 3.08 (n = 35) | 1.02, 14.34 | 0.403 |
1 week | 4.62 ± 2.41 (n = 31) | 1.02, 11.28 | 4.58 ± 3.18 (n = 35) | 1.21, 13.96 | 0.266 | |
1 month | 3.49 ± 1.38 (n = 24) | 1.27, 6.88 | 4.11 ± 2.13 (n = 29) | 2.48, 13.45 | 0.171 | |
NIAvgBUT (s) | Baseline | 5.38 ± 3.22 (n = 32) | 1.15, 15.29 | 5.39 ± 3.08 (n = 35) | 1.02, 14.34 | 0.994 |
1 week | 5.56 ± 3.12 (n = 32) | 0.10, 13.93 | 5.87 ± 3.19 (n = 35) | 1.21, 14.10 | 0.688 | |
1 month | 5.02 ± 1.95 (n = 24) | 1.27, 9.47 | 5.24 ± 2.45 (n = 29) | 2.74, 13.98 | 0.872 | |
F-BUT (s) | Baseline | 4.85 ± 3.66 (n = 34) | 0.00, 15.00 | 5.40 ± 1.91 (n = 34) | 2.00, 9.00 | 0.103 |
1 week | 4.50 ± 2.42 (n = 32) | 1.00, 12.00 | 5.12 ± 2.34 (n = 35) | 1.00, 13.00 | 0.249 | |
1 month | 4.03 ± 2.93 (n = 25) | 0.00, 16.00 | 5.58 ± 2.94 (n = 29) | 1.00, 14.00 | 0.009** | |
Schirmer I test (mm) | Baseline | 11.60 ± 7.50 | 2.00, 30.00 | 11.47 ± 7.56 | 2.00, 30.00 | 0.847 |
1 week | 12.73 ± 8.88 | 2.00, 35.00 | 10.24 ± 6.13 | 1.00, 24.00 | 0.387 | |
1 month | 12.60 ± 9.02 (n = 25) | 2.00, 30.00 | 12.39 ± 7.79 (n = 29) | 2.00, 35.00 | 0.761 | |
Dry eye severity grade (0–2) | Baseline | 0.76 ± 0.92 (0.00,2.00) | 0.80 ± 0.83 (0.00,2.00) | 0.758 | ||
1 week | 1.21 ± 0.84 (0.00,2.00) | 0.51 ± 0.74 (0.00,1.00) | 0.001** | |||
1 month | 1.24 ± 0.93 (0.00,2.00) (n = 25) | 0.45 ± 0.74 (0.00,1.00) (n = 25) | 0.002** |