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Fig. 1 | BMC Ophthalmology

Fig. 1

From: IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Fig. 1

DED causes pyroptosis of hCECs. A-B RT-qPCR to measure the expression of IL-1β and miR-146a-5p; C The viability was determined by CCK-8 assay; D Microscopic observation of cell morphology and numbe; E Apoptosis was detected by flow cytometry; F Western blot analysis to measure GSDMD, NLRP3 and Caspase-1. G IL-18, IL-33 and LDH were determined by ELISA Kit. Asterisks indicate statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001)

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