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Fig. 2 | BMC Ophthalmology

Fig. 2

From: IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Fig. 2

si-IL-1β transfection inhibits pyroptosis of hCECs. A RT-qPCR to measure the expression of IL-1β; B Western blot to measure the expression of IL-1β; C RT-qPCR to measure the expression of miR-146a-5p; D The viability was determined by CCK-8 assay; E Microscopic observation of cell morphology and number; F Apoptosis was detected by flow cytometry; G Western blot analysis to measure GSDMD, NLRP3 and Caspase-1; H IL-18, IL-33 and LDH were determined by ELISA Kit. Asterisks indicate statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001)

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BMC Ophthalmology

ISSN: 1471-2415

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