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Fig. 3 | BMC Ophthalmology

Fig. 3

From: IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Fig. 3

IL-1β effected on pyroptosis of hCECs-DED through miR-146a-5p. A RT-qPCR to measure the expression of miR-146a-5p; B The viability was determined by CCK-8 assay; C Apoptosis was detected by flow cytometry; D Western blot analysis to measure GSDMD, NLRP3 and Caspase-1. E IL-18, IL-33 and LDH were determined by ELISA Kit. Compared with hCECs, *p < 0.05, **p < 0.01; Compared with NC, #p < 0.05, ##p < 0.01; Compared with si-IL-1β, #p < 0.05, ##p < 0.01

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BMC Ophthalmology

ISSN: 1471-2415

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