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Fig. 5 | BMC Ophthalmology

Fig. 5

From: IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Fig. 5

IL-1β/miR-146a-5p/STAT3 influenced pyroptosis of hCECs-400 mOsM. A Western blot analysis to measure STAT3; B The viability was determined by CCK-8 assay; C Apoptosis was detected by flow cytometry; D Western blot analysis to measure GSDMD, NLRP3 and Caspase-1; E IL-18, IL-33 and LDH were determined by ELISA Kit. Compared with hCECs, *p < 0.05, **p < 0.01; Compared with NC, #p < 0.05, ##p < 0.01; Compared with miR-146a-5p mimics, #p < 0.05, ##p < 0.01

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BMC Ophthalmology

ISSN: 1471-2415

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