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Table 3 Association of subfoveal choroidal thickness with study variables using simple and multiple generalized estimating equation (GEE) models

From: Subfoveal choroidal thickness in a general elderly population; Tehran geriatric eye study

Independent variables

Simple model

P-value

Multiple model

P-value

Coefficient (95% CI)

Coefficient (95% CI)

Age

0.23 (-0.08 to 0.55)

0.148

 

NR

Sex (reference: male)

-9.75 (-13.58 to -5.92)

< 0.001

 

NR

Diabetes mellitus

1.52 (-2.68 to 5.72)

0.478

 

NR

Systemic hypertension

0.64 (-4.18 to 5.47)

0.794

 

NR

Body mass index

-0.36 (-0.78 to 0.07)

0.103

 

NR

Cerebrovascular accident

-6.26 (-11.41 to -1.1)

0.017

-4.77 (-9.82 to 0.28)

0.064

Myocardial infarction

-4.06 (-9.68 to 1.56)

0.157

 

NR

Current smoking

1.41 (-4.21 to 7.04)

0.622

 

NR

Alcohol consumption

2.55 (-4.28 to 9.37)

0.465

 

NR

Axial length

1.56 (-0.24 to 3.37)

0.089

 

NR

Anterior chamber depth

6.91 (1.06 to 12.75)

0.021

 

NR

Anterior chamber angle

0.15 (-0.04 to 0.33)

0.120

 

NR

Central corneal thickness

-0.01 (-0.07 to 0.05)

0.760

 

NR

Mean keratometry

0.69 (-0.43 to 1.82)

0.227

 

NR

White-to-white distance

1.81 (-2.36 to 5.98)

0.396

 

NR

Intraocular pressure

0.08 (-0.77 to 0.94)

0.849

 

NR

Pseudophakia (reference: phakia)

5.05 (0.85 to 9.26)

0.018

5.69 (1.55 to 9.83)

0.007

Age-sex interaction

-0.14 (-0.2 to -0.09)

< 0.001

-0.14 (-0.2 to -0.08)

< 0.001

  1. CI: Confidence interval; NR: not retained (P-value > 0.05)