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Table 1 Characteristics of the studies included in the meta-analysis

From: Efficacy and adverse reactions of peripheral add multifocal soft contact lenses in childhood myopia: a meta-analysis

Study

Design

Follow up

(months)

Age

(years)

plus power

Subjects

(E/C)

Treatment lens

Baseline refraction(D)

Treatment effect

Axial length

Myopia control

Cheng

USA, 2019

RCT

12

8–11

+ 0.175 μm

53/59

Positive spherical aberration

-2.25 ± 1.09

37%

18%

Fujikado Japan,2014

RCT

12

10–16

+ 0.50D

24/24

Menicon low-addition

−0.75  − 3.50

47%

26%

Sankaridurg

China, 2019

RCT

24

8–13

+ 1.50D

101/102

Progressive periphery

−0.75  − 3.50

23%

21%

Walline

USA, 2020

RCT

24

7–11

+ 2.50D

97/97

multifocal soft lenses

−1.00  − 6.00

36%

43%

Garcia-del Valle

Spain,2020

RCT

12

7–15

+ 2.00D

36/34

progressive multifocal and reverse geometry

-0.50-8.75

41%

51%

Lina H. Raffa, Malaysia, 2022

RCT

18

13–15

+ 3.00

9/10

Proclear multifocal contact lenses

-2.00-6.00

63%

66.6%

Jenny Huang Jones, USA,

2022

RCT

36

7–11

+ 2.50D

46/46

Biofinity Multifocal “D” contact lenses

-0.75-5.00

43%

50%

Jeffrey J Walline, USA, 2013

prospective, cohort study

24

8–11

+ 2.00

32/32

Proclear Multifocal “D”

-1.00-6.00

50%

29%

Padmaja Sankaridurg, China, 2011

prospective, cohort study

12

7–14

+ 2.00

40/40

novel contact lenses

-0.75-3.50

34%

33%

Jaime Pauné, Spain, 2015

prospective, longitudinal, nonrandomized study

24

9–16

+ 6.00

19/21

soft radial refractive gradient (SRRG) contact lenses

-0.75-7.00

43%

27%

Jianxia Fang, china, 2022

RCT

12

7–15

+ 6.00

22/24

The BioThin (Bio Optic, Inc., Taiwan, China) MFSCLs

-1.00-8.00

26.8%

37%

  1. E = Experiment group; C = Control group; SCLs = Single vision contact lens; RCT = randomized controlled trials