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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Genotype-phenotype associations in CRB1 bi-allelic patients: a novel mutation, a systematic review and meta-analysis

Fig. 3

Best corrected visual acuity variation according to phenotype, mutation types, and specific mutations

A- Boxplot showing the variation of BCVA OU (Log MAR) with respect to phenotype. B- Boxplot showing the variation of BCVA OU (Log MAR) according to several CRB1 bi-allelic mutations. C- Distribution of BCVA OU used as a binary variable (threshold 1.3 LogMar) according to several CRB1 bi-allelic mutations

* P < 0.05, ***P < 0.001

RCD: Rod-cone dystrophy, RD: Rod Dystrophy, LCA: Leber Congenital Amaurosis, BCVA: Best Corrected Visual Activity, OU: Oculus Uterque

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