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Table 3 Results of bi-variable and multivariable analysis of correlates of ECD

From: Corneal endothelial cell density and associated factors among adults at a regional referral hospital in Uganda: a cross-sectional study

Variable

Bi-variable Analysis

  

Multivariable Analysis

  
 

Unadjusted

Coefficient

[95% Confidence Interval]

P value

Adjusted

Coefficient

[95% Confidence Interval]

P value

Sex

      

Female

4.3

-101.5, 110.1

0.9365

70.3

-27.1, 167.6

0.157

Male

Ref

     

Age

-12.9

-15.4, -10.3

< 0.001

-10.1

-13.1, -7.1

< 0.001

Occupation

      

Indoor

183.6

67.4, 299.7

0.0020

   

Outdoor

Ref

     

History of ocular trauma

      

Yes

167.1

13.7, 320.4

0.0328

   

No

Ref

     

History of smoking

      

Yes

-523.7

-857.2, -190.2

0.0022

-439.6

-741.7, -137.6

0.004

No

Ref

     

History of diabetes

      

Yes

-189.0

-367.8, -10.3

0.0382

   

No

Ref

     

History of ocular surgery

      

Yes

-360.6

-618.5, -260.6

< 0.001

-168.0

-312.5, -23.5

0.023

No

Ref

     

History of eye drop use

      

Yes

35.9

-54.1, 246.8

0.5067

   

No

Ref

     

Pterygium

      

Yes

39.1

-103.7, 181.9

0.5905

   

No

Ref

     

Arcus Senilis

      

Yes

-234.9

-401.7, -68.1

0.0059

-132.0

-283.6, 19.5

0.088

No

Ref

     

Pseudoexfoliation

      

Yes

-430.4

-783.1, -77.7

0.0169

   

No

Ref

     

Lens opacification

      

Yes

-376.8

-492.7, -260.9

< 0.001

   

No

Ref

     

Vitreous degeneration

      

Yes

-392.7

-651.0, -134.4

0.0030

   

No

Ref

     

Tear film Instability

      

Yes

-250.4

-406.5, -94.4

0.0017

-136.7

-286.5, -17.3

0.051

No

Ref

     

IOP

8.7

-2.5, 20.0

0.1274

   

Corneal diameter

204.4

102.2, 306.5

0.0001

134.0

39.0, 229.0

0.006

CCT

2.5

1.1, 4.0

0.0008

1.2

-0.04, 2.5

0.058

Keratometry

-28.1

-50.5, -5.6

0.0145

   

AXL

65.2

5.7, 124.7

0.0318

65.8

7.9, 123.8

0.026

ACD

152.9

11.1, 294.7

0.0346