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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Insulin eye drops improve corneal wound healing in STZ-induced diabetic mice by regulating corneal inflammation and neuropeptide release

Fig. 2

Insulin eye drops attenuate inflammatory responses. (A) The typical histopathological changes of diabetic cornea by HE staining in DM-In group mice and DM-Con mice at 72 h (n = 3). Asterisk mark: lymphocytes; black dotted circle: segmented granulocytes. Scale bars: 20 μm. (B) Representative Il-1β (red) expression in corneal epithelium was examined by immunofluorescent techniques at 72 h (n = 3). In the sagittal frozen sections of corneas, Il-1β expression was found mostly within corneal epithelium. Scale bars: 20 μm. DM-In, diabetic mice with topical insulin treatment; DM-Con, diabetic mice with topical physiological saline treatment; Ep, corneal epithelium; St, corneal stroma

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BMC Ophthalmology

ISSN: 1471-2415

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