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Table 1 Demographic and baseline characteristics of all patients

From: Prevalence, clinical characteristics, and independent predictors of uveitic macular edema in an Asian population: a retrospective cohort study

Parameters

Total

(N = 349)

UME

(n = 181)

Non-UME

(n = 168)

P value

Follow-up time (months), mean ± SD

39.95 ± 33.65

36.65 ± 30.60

43.49 ± 36.41

0.058

Age (years), mean ± SD

40.6 ± 16.6

42.2 ± 16.3

38.9 ± 16.7

0.063

Female gender, n (%)

200 (57.3)

97 (53.6)

103 (61.3)

0.150

Bilateral uveitis, n (%)

190 (54.4)

92 (50.8)

98 (58.3)

0.160

Chronic uveitis, n (%)

255 (73.1)

126 (69.6)

129 (76.8)

0.130

Location of inflammation, n (%)

    

 Intermediate uveitis

59 (16.9)

20 (11.1)

39 (23.2)

0.009*

 Posterior uveitis

144 (41.3)

82 (45.3)

62 (36.9)

 

 Panuveitis

146 (41.8)

79 (43.7)

67 (39.9)

 

Type of inflammation, n (%)

    

 Granulomatous inflammation

175 (50.1)

90 (49.7)

85 (50.6)

0.870

 Nongranulomatous inflammation

174 (49.9)

91 (50.3)

83 (49.4)

 

Etiology, n (%)

    

 Infection

131 (37.5)

85 (47.0)

46 (27.4)

0.001*

 Immune-mediated

88 (25.2)

37 (20.4)

51 (30.4)

 

 Idiopathic

130 (37.3)

59 (32.6)

71 (42.3)

 

Diagnosis, n (%)

    

 Tuberculosis

44 (12.6)

25 (13.8)

19 (11.3)

 

 ARN/PORN/CMVR

42 (12)

28 (15.5)

14 (8.3)

 

 Vogt-Koyanagi-Harada disease

27 (7.7)

16 (8.8)

11 (6.5)

 

 White dot syndrome

19 (5.4)

2 (1.1)

17 (10.1)

 

 Parasite-related uveitis

18 (5.2)

11 (6.1)

7 (4.2)

 

 Sarcoidosis

17 (4.9)

8 (4.4)

9 (5.4)

 

 Behçet’s disease

13(3.7)

6 (3.3)

7 (4.2)

 

 Syphilis

9 (2.6)

7 (3.9)

2 (1.2)

 

 HLA-B27/SNSA a

7 (2)

1 (0.5)

6 (3.6)

 

 Toxoplasmosis

7 (2)

6 (3.3)

1 (0.6)

 

 Cat-scratch neuroretinitis

6 (1.7)

4 (2.2)

2 (1.2)

 

 Endogenous endophthalmitis

5 (1.4)

4 (2.2)

1 (0.6)

 

 Juvenile idiopathic arthritis b

3 (0.9)

3 (1.7)

0

 

 Systemic lupus erythematosus

2 (0.6)

1 (0.5)

1 (0.6)

 

 Maximal macular thickness (µm), mean ± SD

358.11 ± 136.26

443.66 ± 142.29

265.94 ± 19.68

< 0.001*

  1. ARN acute retinal necrosis; CMVR cytomegalovirus retinitis; HLA human leukocyte antigen; PORN progressive outer retinal necrosis; SD standard deviation; SNSA seronegative spondyloarthropathy; UME uveitic macular edema
  2. a Among 7 patients with HLA-B27/SNSA, 4 had intermediate uveitis, and 3 had panuveitis
  3. b Among 3 patients with JIA, 2 had intermediate uveitis, and 1 had panuveitis