Choroidal manifestations of non-ocular sarcoidosis: an enhanced depth imaging OCT study

BMC Ophthalmology

Table 3 Factors associated with choroidal thickness

	Univariate						Multivariable
Control	Total		SLCC		HL		Total		SLCC		HL
	r²	p	r²	p	r²	p	r²	p	r²	p	r²	p
Systemic factors
Age	0.200	0.013**	0.183	0.018**	0.143	0.039**	0.200	0.013**	0.183	0.018**	0.143	0.039**
Sex		0.413		0.164		0.880
Ocular factors
BCVA	0.015	0.520	0.034	0.327	0.006	0.682		0.775		0.503		0.928
SE	0.186	0.017**	0.178	0.020**	0.130	0.049**		0.246		0.242		0.358
IOP	0.067	0.167	0.066	0.172	0.047	0.252		0.197		0.308		0.415
Non-ocular sarcoidosis	Total		SLCC		HL		Total		SLCC		HL
	r²	p	r²	p	r²	p	r²	p	r²	p	r²	p
Systemic factors
Age	0.001	0.870	0.000	0.990	0.001	0.857	0.175	0.636	0.154	0.893	0.191	0.549
Sex		0.363		0.194		0.579
Subtypes of sarcoidosis
Pulmonary vs. Extra-pulmonary		0.912		0.748		0.870
Duration of sarcoidosis	0.052	0.224	0.005	0.724	0.055	0.211		0.516		0.987		0.450
Treatment regimen
Steroid vs. observation		0.015**		0.073*		0.082*
Methotrexate vs. observation		0.327		0.787		0.327
ACE	0.076	0.149	0.020	0.461	0.072	0.161		0.405		0.869		0.366
CRP	0.022	0.441	0.056	0.215	0.007	0.676		0.726		0.105		0.898
Ocular factors
BCVA	0.002	0.819	0.030	0.364	0.013	0.552		0.727		0.412		0.914
SE	0.035	0.323	0.014	0.535	0.028	0.373		0.209		0.965		0.150
IOP	0.017	0.495	0.003	0.780	0.016	0.502		0.874		0.478		0.941

SLCC Sattler layer-choriocapillaris complex, HL Haller layer, ACE angiotensin converting enzyme, CRP C-reactive protein, BCVA best corrected visual acuity, SE spherical equivalent, IOP intraocular pressure
^**Statistically significant (p < 0.05) and *borderline significant (p < 0.1); Linear regression analysis for continuous variable and Chi-squared test for categorical variables

ISSN: 1471-2415