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Table 2 Analyses of Risk Factors for depression in Patients with and without glaucoma

From: The association between glaucoma and risk of depression: a nationwide population-based cohort study

Predictive variables

Univariate analysis

Multivariable analysis

Unadjusted HR (95% CI)

P value

Adjusted HR (95% CI)

P value

Glaucoma (Yes vs. No)

1.71(1.54–1.89)

< 0.0001

1.71(1.54–1.89)

< 0.0001

Age

 30–50

Reference

 

Reference

 

 50–60

1.39(1.21–1.60)

< 0.0001

1.32(1.14–1.52)

< 0.001

 60–70

1.53(1.34–1.75)

< 0.0001

1.40(1.21–1.61)

< 0.0001

 ≥70

1.61(1.41–1.85)

< 0.0001

1.49(1.29–1.72)

< 0.0001

Gender (Male vs Female)

0.64(0.59–0.71)

< 0.0001

0.67(0.61–0.74)

< 0.0001

Charlson comorbidity index

  < 3

Reference

 

Reference

 

 ≥3

1.16(1.02–1.32)

< 0.05

1.04(0.91–1.19)

0.59

Insurance cost

  < 40,000 NTD

Reference

 

Reference

 

 ≥40,000 NTD

0.61(0.51–0.73)

< 0.0001

0.77(0.64–0.92)

< 0.01

Urbanization level

 Urban

Reference

 

Reference

 

 Rural

1.03(0.93–1.14)

0.56

0.99(0.89–1.10)

0.85

Living alone

 No

Reference

 

Reference

 

 Yes

1.22(1.06–1.42)

< 0.01

1.20(1.03–1.41)

< 0.05

Substance abuse

    

 No

Reference

 

Reference

 

 Yes

1.54(1.09–2.18)

< 0.05

1.44(1.03–1.82)

< 0.05

  1. NTD New Taiwan Dollar, HR hazard ratio, CI confidence interval,
  2. In the multivariable analysis, all the other variables in the Table are included for adjustment
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BMC Ophthalmology

ISSN: 1471-2415

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