Narayan DS, Wood JPM, Chidlow G, Casson RJ. A review of the mechanisms of cone degeneration in retinitis pigmentosa. Acta Ophthalmol. 2016;94(8):748–54.
Article
PubMed
Google Scholar
Zhang Q. Retinitis pigmentosa. Asia-Pac J Ophthalmol. 2016;5(4):265–71.
Article
CAS
Google Scholar
Garoon RB, Stout JT. Update on ocular gene therapy and advances in treatment of inherited retinal diseases and exudative macular degeneration. Curr Opin Ophthalmol. 2016;27(3):268–73.
Article
PubMed
Google Scholar
Vaidya A, Borgonovi E, Taylor RS, Sahel JA, Rizzo S, Stanga P, et al. The cost-effectiveness of the Argus II retinal prosthesis in retinitis Pigmentosa patients. BMC Ophthalmol. 2014;14:49.
Article
PubMed
PubMed Central
Google Scholar
He Y, Zhang Y, Su G. Recent advances in treatment of retinitis pigmentosa. Curr Stem Cell Res Ther. 2015;10(3):258–65.
Article
CAS
PubMed
Google Scholar
Gao J, Hussain RM, Weng CY. Voretigene neparvovec in retinal diseases: a review of the current clinical evidence. Clin Ophthalmol. 2020;14:3855–69.
Article
CAS
PubMed
PubMed Central
Google Scholar
Maguire AM, Bennett J, Aleman EM, Leroy BP, Aleman TS. Clinical perspective: treating RPE65- associated retinal dystrophy. Mol Ther. 2020;29(2):442–63.
Article
PubMed
PubMed Central
Google Scholar
Kang C, Scott LJ. Voretigene neparvovec: a review in RPE65 mutation-associated inherited retinal dystrophy. Mol Diagn Ther. 2020;24(4):487–95.
Article
CAS
PubMed
Google Scholar
Mo M, Wang S, Zhou Y, Li H, Wu Y. Mesenchymal stem cell subpopulations: phenotype, property and therapeutic potential. Cell Mol Life Sci. 2016;73(17):3311–21.
Article
CAS
PubMed
Google Scholar
Markov A, Thangavelu L, Aravindhan S, Zekiy AO, Jarahian M, Chartrand MS, et al. Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders. Stem Cell Res Ther. 2021;12(1):192.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hong HS, Kim YH, Son Y. Perspectives on mesenchymal stem cells: tissue repair, immune modulation, and tumor homing. Arch Pharm Res. 2012;35(2):201–11.
Article
CAS
PubMed
Google Scholar
Liu DN, Yin ZQ, Wu N, Wang YH, Chen LF. Rat bone marrow stromal cells express retinal phenotypic markers following different induction protocols. Ophthalmic Res. 2009;41(4):186–93.
Article
CAS
PubMed
Google Scholar
Duan P, Xu H, Zeng Y, Wang Y, Yin ZQ. Human bone marrow stromal cells can differentiate to a retinal pigment epithelial phenotype when co-cultured with pig retinal pigment epithelium using a transwell system. Cell Physiol Biochem. 2013;31(4–5):601–13.
Article
CAS
PubMed
Google Scholar
Ng TK. Progress of mesenchymal stem cell therapy for neural and retinal diseases. World J Stem Cells. 2014;6(2):111.
Article
PubMed
PubMed Central
Google Scholar
Gu X, Yu X, Zhao C, Duan P, Zhao T, Liu Y, et al. Efficacy and safety of autologous bone marrow mesenchymal stem cell transplantation in patients with diabetic retinopathy. Cell Physiol Biochem. 2018;49(1):40–52.
Article
CAS
PubMed
Google Scholar
Moll G, Ankrum JA, Kamhieh-Milz J, Bieback K, Ringdén O, Volk H-D, et al. Intravascular mesenchymal stromal/stem cell therapy product diversification: time for new clinical guidelines. Trends Mol Med. 2019;25(2):149–63.
Article
PubMed
Google Scholar
Ra JC, Shin IS, Kim SH, Kang SK, Kang BC, Lee HY, et al. Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans. Stem Cells Dev. 2011;20(8):1297–308.
Article
CAS
PubMed
Google Scholar
Tzameret A, Sher I, Belkin M, Treves AJ, Meir A, Nagler A, et al. Epiretinal transplantation of human bone marrow mesenchymal stem cells rescues retinal and vision function in a rat model of retinal degeneration. Stem Cell Res. 2015;15(2):387–94.
Article
CAS
PubMed
Google Scholar
Jian Q, Li Y, Yin ZQ. Rat BMSCs initiate retinal endogenous repair through NGF/TrkA signaling. Exp Eye Res. 2015;132:34–47.
Article
CAS
PubMed
Google Scholar
Satarian L, Nourinia R, Safi S, Kanavi MR, Baharvand H. Intravitreal injection of bone marrow mesenchymal stem cells in patients with advanced retinitis pigmentosa; a safety study. J Ophthalmic Vis Res. 2017;12(1):58.
Article
PubMed
PubMed Central
Google Scholar
Zhao T, Liang Q, Meng X, Duan P, Wang F, Li S, et al. Intravenous infusion of umbilical cord mesenchymal stem cells maintains and partially improves visual function in patients with advanced retinitis pigmentosa. Stem Cells Dev. 2020;29(16):1029–37.
Article
CAS
PubMed
Google Scholar
Li T, Xia M, Gao Y, Chen Y, Xu Y. Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy. Expert Opin Biol Ther. 2015;15(9):1293–306.
Article
PubMed
Google Scholar
de Witte SFH, Merino AM, Franquesa M, Strini T, van Zoggel JAA, Korevaar SS, et al. Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease. Stem Cell Res Ther. 2017;8(1):140.
Article
PubMed
PubMed Central
Google Scholar
Matheakakis A, Batsali A, Papadaki HA, Pontikoglou CG. Therapeutic implications of mesenchymal stromal cells and their extracellular vesicles in autoimmune diseases: from biology to clinical applications. Int J Mol Sci. 2021;22(18):10132.
de Witte SFH, Luk F, Sierra Parraga JM, Gargesha M, Merino A, Korevaar SS, et al. Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by Monocytic cells. Stem Cells. 2018;36(4):602–15.
Article
PubMed
Google Scholar
Muller L, Tunger A, Wobus M, von Bonin M, Towers R, Bornhauser M, et al. Immunomodulatory properties of Mesenchymal stromal cells: an update. Front Cell Dev Biol. 2021;9:637725.
Article
PubMed
PubMed Central
Google Scholar
Podesta MA, Remuzzi G, Casiraghi F. Mesenchymal stromal cells for transplant tolerance. Front Immunol. 2019;10:1287.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang LT, Liu KJ, Sytwu HK, Yen ML, Yen BL. Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: use of cell-free products and human pluripotent stem cell-derived mesenchymal stem cells. Stem Cells Transl Med. 2021;10(9):1288–303.
Article
CAS
PubMed
PubMed Central
Google Scholar
Eggenhofer E, Benseler V, Kroemer A, Popp FC, Geissler EK, Schlitt HJ, et al. Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion. Front Immunol. 2012;3:297.
Article
CAS
PubMed
PubMed Central
Google Scholar
Saat TC, van den Engel S, Bijman-Lachger W, Korevaar SS, Hoogduijn MJ, Ijzermans JNM, et al. Fate and effect of intravenously infused mesenchymal stem cells in a mouse model of hepatic ischemia reperfusion injury and resection. Stem Cells Int. 2016;2016:5761487.
Article
CAS
PubMed
PubMed Central
Google Scholar
Strauss O, Stumpff F, Mergler S, Wienrich M, Wiederholt M. The Royal College of surgeons rat: an animal model for inherited retinal degeneration with a still unknown genetic defect. Acta Anat (Basel). 1998;162(2–3):101–11.
Article
CAS
Google Scholar
Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG, et al. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet. 2000;26(3):270–1.
Article
CAS
PubMed
Google Scholar
Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini FC, Krause DS, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8(4):315–7.
Article
CAS
PubMed
Google Scholar
Chao K, Zhang S, Qiu Y, Chen X, Zhang X, Cai C, et al. Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5+ B regulatory cells. Stem Cell Res Ther. 2016;7(1):109.
Article
PubMed
PubMed Central
Google Scholar
Cortes-Dericks L. Human mesenchymal stem cell-derived conditioned medium: perspectives for therapeutic application in lung cancers. J Tissue Sci Eng. 2017;8(2):25.
Article
Google Scholar
Nagamura-Inoue T. Umbilical cord-derived mesenchymal stem cells: their advantages and potential clinical utility. World J Stem Cells. 2014;6(2):195.
Article
PubMed
PubMed Central
Google Scholar
El Omar R, Beroud J, Stoltz JF, Menu P, Velot E, Decot V. Umbilical cord mesenchymal stem cells: the new gold standard for mesenchymal stem cell-based therapies? Tissue Eng B Rev. 2014;20(5):523–44.
Article
Google Scholar
Li X, Bai J, Ji X, Li R, Xuan Y, Wang Y. Comprehensive characterization of four different populations of human mesenchymal stem cells as regards their immune properties, proliferation and differentiation. Int J Mol Med. 2014;34(3):695–704.
Article
PubMed
PubMed Central
Google Scholar
Borys-Wojcik S, Brazert M, Jankowski M, Ozegowska K, Chermula B, Piotrowska-Kempisty H, et al. Human Wharton's jelly mesenchymal stem cells: properties, isolation and clinical applications. J Biol Regul Homeost Agents. 2019;33(1):119–23.
CAS
PubMed
Google Scholar
Batsali AK, Kastrinaki MC, A. Papadaki H, Pontikoglou C. Mesenchymal stem cells derived from Wharton's jelly of the umbilical cord: biological properties and emerging clinical applications. Curr Stem Cell Res Ther. 2013;8(2):144–55.
Article
CAS
PubMed
Google Scholar
Meng F, Xu R, Wang S, Xu Z, Zhang C, Li Y, et al. Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial. Signal Transduct Target Ther. 2020;5(1):172.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang L, Huang S, Li S, Li M, Shi J, Bai W, et al. Efficacy and safety of umbilical cord Mesenchymal stem cell therapy for rheumatoid arthritis patients: A prospective phase I/II study. Drug Des Devel Ther. 2019;13:4331–40.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lee RH, Pulin AA, Seo MJ, Kota DJ, Ylostalo J, Larson BL, et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell. 2009;5(1):54–63.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI, et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev. 2009;18(5):683–92.
Article
CAS
PubMed
Google Scholar
Kim M, Bae YK, Um S, Kwon JH, Kim GH, Choi SJ, et al. A small-sized population of human umbilical cord blood-derived mesenchymal stem cells shows high stemness properties and therapeutic benefit. Stem Cells Int. 2020;2020:1–17.
Google Scholar
Chin SP, Mohd-Shahrizal MY, Liyana MZ, Then KY, Cheong SK. High dose of intravenous allogeneic umbilical cord-derived Mesenchymal stem cells (CLV-100) infusion displays better Immunomodulatory effect among healthy volunteers: A phase 1 clinical study. Stem Cells Int. 2020;2020:8877003.
Article
PubMed
PubMed Central
Google Scholar
Stefanska K, Ozegowska K, Hutchings G, Popis M, Moncrieff L, Dompe C, et al. Human Wharton's jelly-cellular specificity, Stemness potency, animal models, and current application in human clinical trials. J Clin Med. 2020;9(4):1102.
Nystedt J, Anderson H, Tikkanen J, Pietila M, Hirvonen T, Takalo R, et al. Cell surface structures influence lung clearance rate of systemically infused mesenchymal stromal cells. Stem Cells. 2013;31(2):317–26.
Article
CAS
PubMed
Google Scholar
Zanetti A, Grata M, Etling EB, Panday R, Villanueva FS, Toma C. Suspension-expansion of bone marrow results in small mesenchymal stem cells exhibiting increased transpulmonary passage following intravenous administration. Tissue Eng C Methods. 2015;21(7):683–92.
Article
CAS
Google Scholar
Ge J, Guo L, Wang S, Zhang Y, Cai T, Zhao RCH, et al. The size of mesenchymal stem cells is a significant cause of vascular obstructions and stroke. Stem Cell Rev Rep. 2014;10(2):295–303.
Article
CAS
PubMed
Google Scholar
Wang L, Li P, Tian Y, Li Z, Lian C, Ou Q, et al. Human umbilical cord mesenchymal stem cells: subpopulations and their difference in cell biology and effects on retinal degeneration in RCS rats. Cell Physiol Biochem. 2018;17(6):421–35.
Google Scholar
Qu L, Gao L, Xu H, Duan P, Zeng Y, Liu Y, et al. Combined transplantation of human mesenchymal stem cells and human retinal progenitor cells into the subretinal space of RCS rats. Sci Rep. 2017;7(1):199.
Article
PubMed
PubMed Central
Google Scholar
Jin SZ, Liu BR, Xu J, Gao FL, Hu ZJ, Wang XH, et al. Ex vivo-expanded bone marrow stem cells home to the liver and ameliorate functional recovery in a mouse model of acute hepatic injury. Hepatobil Pancreat Dis Int. 2012;11(1):66–73.
Article
Google Scholar
Kang SK, Shin IS, Ko MS, Jo JY, Ra JC. Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy. Stem Cells Int. 2012;2012:342968.
Article
PubMed
PubMed Central
Google Scholar
Wang S, Lu B, Girman S, Duan J, McFarland T, Zhang QS, et al. Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology. PLoS One. 2010;5(2):e9200.
Article
PubMed
PubMed Central
Google Scholar
Gnecchi M, Danieli P, Malpasso G, Ciuffreda MC. Paracrine mechanisms of mesenchymal stem cells in tissue repair. Methods Mol Biol. 2016;1416:123–46.
Article
CAS
PubMed
Google Scholar
Jung H, Chun MS, Chang MS. Sorting of human mesenchymal stem cells by applying optimally designed microfluidic chip filtration. Analyst. 2015;140(4):1265–74.
Article
CAS
PubMed
Google Scholar
Majore I, Moretti P, Hass R, Kasper C. Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord. Cell Commun Signal. 2009;7:6.
Article
PubMed
PubMed Central
Google Scholar