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  1. Sturge–Weber Syndrome (SWS) is a rare disease involving the eye, skin, and brain. Port-wine stain (PWS) and glaucoma are common clinical manifestations. This study analysed the clinical characteristics of infa...

    Authors: Honggai Yan, Man Hu, Yanhui Cui, Li Li and Tianwei Liang
    Citation: BMC Ophthalmology 2022 22:260
  2. The treatment for diabetic macular edema (DME) has revolutionized during the last 15 years after the introduction of intravitreal anti-VEGF agents. The aim of the current study is to evaluate the real-world vi...

    Authors: Joonas Wirkkala, Anna-Maria Kubin, Pasi Ohtonen, Joona Yliselä, Taru Siik and Nina Hautala
    Citation: BMC Ophthalmology 2022 22:258
  3. Interest in developing alternative methods for the treatment of amblyopia has long been a topic of interest among clinicians and researchers, as prescribed occlusion and penalization therapies do not always pr...

    Authors: L. Leal Vega, D. P. Piñero, C. J. Hernández Rodríguez, A. Molina Martín, L. Morales-Quezada, A. I. Vallelado Álvarez, J. F. Arenillas Lara and M. B. Coco Martín
    Citation: BMC Ophthalmology 2022 22:253
  4. Diabetic retinopathy (DR) is characterized by ischemia, hypoxia, and angiogenesis. Erythropoietin (EPO), an angiogenic hormone, is upregulated in DR, and the association of EPO genetic variants with DR is still u...

    Authors: Luís Fernando Castagnino Sesti, Renan Cesar Sbruzzi, Evelise Regina Polina, Douglas dos Santos Soares, Daisy Crispim, Luís Henrique Canani and Kátia Gonçalves dos Santos
    Citation: BMC Ophthalmology 2022 22:250
  5. Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss. A novel technology micropulse laser trabeculoplasty (MLT) can use duty-circle subvisible laser pulses to treat glaucom...

    Authors: Yuting Yang, Xinting Huang, Sheng Liao, Feng Zhang, Jingming Shi, Xuanchu Duan and Ke Liu
    Citation: BMC Ophthalmology 2022 22:249
  6. The prevalence of myopia has increased in recent years, with changes being dynamic and uneven in different regions. The purpose of this study is to evaluate the prevalence of visual impairment caused by myopia...

    Authors: Mila Dragomirova, Albena Antonova, Slavena Stoykova, Gergana Mihova and Denitsa Grigorova
    Citation: BMC Ophthalmology 2022 22:248
  7. Patients with central retinal vein occlusion (CRVO) and macular edema often are treated by intravitreal ranibizumab injection (IRI). The role of changes in macular sensitivity in the positive effects of IRI on...

    Authors: Taro Otawa, Hidetaka Noma, Kanako Yasuda, Akitomo Narimatsu, Masaki Asakage, Akina Tanaka, Hiroshi Goto and Masahiko Shimura
    Citation: BMC Ophthalmology 2022 22:247
  8. Keratoconus (KC) is a noninflammatory corneal ectatic disorder. In 2015, the Global Consensus on Keratoconus and Ectatic Diseases agreed that the pathophysiology of KC includes environmental, biomechanical, ge...

    Authors: Alain Saad, Maria Rizk and Damien Gatinel
    Citation: BMC Ophthalmology 2022 22:245
  9. We present a case of retinal occlusive vasculitis following brolucizumab administration and the first report of optical coherence tomography angiography (OCTA) findings after treatment.

    Authors: Eun Kyoung Lee, Baek-Lok Oh, Chang Ki Yoon and Un Chul Park
    Citation: BMC Ophthalmology 2022 22:244
  10. To determine the pattern of axial variation in subjects with initial shortened axial length during the entire period of orthokeratology and to discuss the possibility of shortened AL after one month of orthoke...

    Authors: Anken Wang, Chenhao Yang, Li Shen, Jiaying Wang, Zhehuan Zhang and Weiming Yang
    Citation: BMC Ophthalmology 2022 22:243
  11. To assess visual quality and stabilization of refractive changes in corneal edema patients after cataract surgery, using visual acuity (VA) and contrast sensitivity measurements.

    Authors: Mª Amparo Díez-Ajenjo, Mª José Luque-Cobija, Cristina Peris-Martínez, Susana Ortí-Navarro and Mª Carmen García-Domene
    Citation: BMC Ophthalmology 2022 22:242
  12. To assess the depth of field (DOF) by means of defocus curve analysis applying different visual acuity criteria in patients following cataract surgery and bilateral implantation of a new trifocal diffractive i...

    Authors: Carlos Palomino-Bautista, Alejandro Cerviño, Ricardo Cuiña-Sardiña, David Carmona-Gonzalez, Alfredo Castillo-Gomez and Ruben Sanchez-Jean
    Citation: BMC Ophthalmology 2022 22:240
  13. Activation of the NOD-like receptor protein 3 (NLRP3) inflammasome pathway has been implicated in Diabetic retinopathy (DR) pathogenesis, but its impact on DR development and progression remains unclear. There...

    Authors: Charisse Y. J. Kuo, Rinki Murphy, Ilva D. Rupenthal and Odunayo O. Mugisho
    Citation: BMC Ophthalmology 2022 22:238
  14. Screening for diabetic retinopathy (DR) is suboptimal, and patients with diabetes who present to the emergency department (ED) may be at particularly high risk of undiagnosed DR. The purpose of this study is t...

    Authors: Andrew M. Williams, Jared M. Weed, Patrick W. Commiskey, Gagan Kalra and Evan L. Waxman
    Citation: BMC Ophthalmology 2022 22:237
  15. To compare the quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy (TPRK) and off-flap epipolis-laser in situ keratomileusis (Epi-LASIK) in moderate to high...

    Authors: Yunjie Zhang, Tiankun Li, Zhangliang Li, Mali Dai, Qinmei Wang and Chenchen Xu
    Citation: BMC Ophthalmology 2022 22:234
  16. Information on the centration and tilt of iris-claw intraocular lenses (IC-IOLs) is limited. In this study, we tested the capacity of an anterior segment optical coherence tomography (AS-OCT) instrument to mea...

    Authors: Giacomo Calzetti, Carlo Bellucci, Salvatore Antonio Tedesco, Maurizio Rossi, Stefano Gandolfi and Paolo Mora
    Citation: BMC Ophthalmology 2022 22:233
  17. Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes. DR involves a state of systemic inflammation, and chronic inflammation can promote microvascular and macrovascular d...

    Authors: Lili Huang, Lele Li, Min Wang, Dongmei Zhang and Yu Song
    Citation: BMC Ophthalmology 2022 22:231
  18. During the first wave of the coronavirus disease 2019 (COVID-19) pandemic in 2020 outpatient care of neovascular age-related macular degeneration (nAMD) patients was severely reduced due to lockdown. Missed vi...

    Authors: Stephan Szegedi, Christian Ebner, Kata Miháltz, Tobias Wachter and Pia Veronika Vécsei-Marlovits
    Citation: BMC Ophthalmology 2022 22:228
  19. To compare the safety and efficacy of Ab-externo subretinal bands removal in comparison with the classical Ab-interno approach during pars plana vitrectomy for primary rhegmatogenous retinal detachment.

    Authors: Samir Elbaha, Mohammed Ghoneem, Amir abousamra and Mahmoud Abouhussein
    Citation: BMC Ophthalmology 2022 22:227
  20. To evaluate the surgical outcome of epicanthus and telecanthus correction by C-U medial canthoplasty with lateral canthoplasty in Blepharophimosis Syndrome.

    Authors: Ahmed Ali Amer, Marwa Mahmoud Abdellah, Nader Hussein Fouad Hassan and Amr Mounir
    Citation: BMC Ophthalmology 2022 22:226
  21. To analyze the level changes of 28 cytokines in aqueous humor of patients with proliferative diabetic retinopathy (PDR) coexisting neovascular glaucoma (NVG) after intravitreal injection of conbercept (IVC), a...

    Authors: Qing Xu, Chaoju Gong, Lei Qiao, Ruifang Feng, Haiyang Liu, Yalu Liu, Liu Yang, Wei Fan, Lina Guan, Jie Li, Yipeng Zhang and Suyan Li
    Citation: BMC Ophthalmology 2022 22:224
  22. Primary angle closure glaucoma (PACG) is the most common type of glaucoma in China. Laser peripheral iridotomy (LPI) is the primary choice to treat PAC: We aim to evaluate the changes of biometric parameters o...

    Authors: Bo Yu, Kang Wang, Xiaomin Zhang and Xiaoli Xing
    Citation: BMC Ophthalmology 2022 22:222
  23. Polycythemia vera (PV) is a myeloproliferative neoplasm with increased hemoglobin, hematocrit, platelet count and leukocytosis, resulting in increased blood viscosity. PV which is initially presenting with ocu...

    Authors: Jasmin Regensburger, Teresa Rauchegger, Lorin Loacker, Florian Falkner, Clemens Feistritzer and Barbara Teuchner
    Citation: BMC Ophthalmology 2022 22:221
  24. The increase in the prevalence of myopia has become a matter of serious public health concern, and few studies to date have examined the ocular biometric parameters of myopia in young Chinese adults. This stud...

    Authors: Xue Bai, Nan Jin, Qingxin Wang, Yicheng Ge, Bei Du, Di Wang, Qiang Su, Biying Wang, Chi-ho To and Ruihua Wei
    Citation: BMC Ophthalmology 2022 22:220
  25. Oguchi disease is a rare type of congenital stationary night blindness associated with an abnormal fundus appearance. It is inherited in an autosomal recessive manner where two types exist according to the gen...

    Authors: Caroline Atef Tawfik, Nagham Maher Elbagoury, Noha Ibrahim Khater and Mona Lotfi Essawi
    Citation: BMC Ophthalmology 2022 22:217
  26. Few case reports have described sildenafil overdose, particularly ingestion of > 1000 mg, and overdose-induced changes in visual function remain unclear. We report retinal morphology, retinal sensitivity, and ...

    Authors: Gen Miura, Takayuki Baba, Ryusuke Hashimoto and Shuichi Yamamoto
    Citation: BMC Ophthalmology 2022 22:216
  27. Although relationship between the retinal vessel caliber (RVC) and glaucoma is well known, there has been a paucity of information on the effects of glaucoma-related optic nerve head (ONH) structural factors o...

    Authors: Aiko Iwase, Tae Tsutsumi, Ryo Kawasaki, Jun Suehiro, Akihiko Sekine and Makoto Araie
    Citation: BMC Ophthalmology 2022 22:215
  28. This study was investigated the surgical outcomes of primary rhegmatogenous retinal detachment (RRD) with inferior retinal breaks (IRBs) that were repaired by 25-gauge pars plana vitrectomy (PPV) with air tamp...

    Authors: Yongping Tang, Bo Lin, Jing Chen, Daosen Chen and Ronghan Wu
    Citation: BMC Ophthalmology 2022 22:213
  29. To investigate the prevalence of myopia in Chinese primary school students and their ocular biometrics including axial length (AL), corneal radius of curvature (CRC) and spherical equivalent refraction (SER). ...

    Authors: Yu Yue, Xianmao Liu, Shu Yi, Bo Liu, Hong Yi and Hong Li
    Citation: BMC Ophthalmology 2022 22:212
  30. To report a case of a patient showing bilateral corneal opacities after amantadine chronic treatment for Parkinson’s Disease (PD) and corneal edema associated with intra-epithelial and -endothelial depositions...

    Authors: Michela Cennamo, Francesco Dragotto, Eleonora Favuzza, Alberto Morelli and Rita Mencucci
    Citation: BMC Ophthalmology 2022 22:211

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