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  1. With the rapid development of intraocular collamer lens (ICL) operation, it is foreseeable that we will encounter a large number of glaucoma patients with ICL implantation history. However, our current underst...

    Authors: Wei Wei, Xueqing Yu, Lu Yang, Chan Xiong and Xu Zhang
    Citation: BMC Ophthalmology 2021 21:268
    Content type: Case report Published on:

  2. Demographic, systemic and ocular factors may impact macular ganglion cell–inner plexiform layer (GCIPL) thickness measurements. This study aimed to investigate the influences of multiple potential determinants...

    Authors: Xiaoyu Xu, Hui Xiao, Kunbei Lai, Xinxing Guo, Jingyi Luo and Xing Liu
    Citation: BMC Ophthalmology 2021 21:267
    Content type: Research article Published on:

  3. Micropulse transscleral cyclophotocoagulation (MP-CPC) is a technique that has been approved in recent years to treat glaucoma. MP-CPC causes anterior chamber inflammation; a relationship with reduced intraocu...

    Authors: Akitoshi Kimura, Kei-Ichi Nakashima and Toshihiro Inoue
    Citation: BMC Ophthalmology 2021 21:266
    Content type: Research Published on:

  4. Occupational predisposition to dry eye disease is known. Simultaneous exposure to multiple factors may pose more risk. Street sweepers are exposed to sunlight in addition to dust which all sweepers are exposed...

    Authors: Chigozie I. Echieh, Bassey A. Etim, Chidiebere Peter Echieh, Taiwo Oyeniyi and Jeff Ajewole
    Citation: BMC Ophthalmology 2021 21:265
    Content type: Research article Published on:

  5. Visual fixation may be affected in amblyopic patients and, moreover, its stability may be associated with the effects of amblyopic treatments on visual performance in patients with strabismus. Therefore, fixat...

    Authors: Otto Alexander Maneschg, Mirella Telles Salgueiro Barboni, Zoltán Zsolt Nagy and János Németh
    Citation: BMC Ophthalmology 2021 21:264
    Content type: Research Published on:

  7. Glaucomatous eyes often show strong intraocular pressure (IOP) fluctuations and individual measurements at different time points are necessary for personalized therapy. To survey IOP variations 48-hours diurna...

    Authors: Marion Zimmermann, Bert C. Giers, Anna Beck, Katharina Bell, Herwig Zimmermann, Marlene Hechtner, Esther M. Hoffmann, Norbert Pfeiffer and Katrin Lorenz
    Citation: BMC Ophthalmology 2021 21:262
    Content type: Research article Published on:

  8. To evaluate microstructural changes in the meibomian glands (MGs) in patients with active and inactive Graves’ orbitopathy (GO), using in vivo confocal microscopy (IVCM), and to investigate the correlations be...

    Authors: Shengnan Cheng, Yueqi Yu, Jin Chen, Lin Ye, Xinghua Wang and Fagang Jiang
    Citation: BMC Ophthalmology 2021 21:261
    Content type: Research article Published on:

  9. Our study aimed to explore the prevalence and risk factors of refractive error (RE) in Han and Tibetan population aged 50–79 years in Xining and surrounding areas in Qinghai Province on Qinghai-Tibet Plateau.

    Authors: Meng Wang, Linyang Gan, Jiantao Cui, Guangliang Shan, Ting Chen, Xianghua Wang, Yuhan Wang, Li Pan, Zhanquan Li, Sen Cui, Airong Yang, Wenfang Li, Guoqiang Jia, Ximing Han, Huijing He, Yong Zhong…
    Citation: BMC Ophthalmology 2021 21:260
    Content type: Research Published on:

  10. Diabetic retinopathy is the most common microvascular complication of diabetes; however, early changes in retinal microvessels are difficult to detect clinically, and a patient’s vision may have begun to deter...

    Authors: Xinyue Li, Yu Yu, Xueting Liu, Yan Shi, Xin Jin, Yanyan Zhang, Shuo Xu, Nan Zhang, Li Dong, Sujun Zhou, Yingbin Wang, Yiheng Ding, Zhen Song and Hong Zhang
    Citation: BMC Ophthalmology 2021 21:259
    Content type: Research Published on:

  11. During the coronavirus disease 2019 (COVID-19) epidemic, due to the traffic blockade and the shortage of medical resources, more and more premature infants could not receive timely and effective ROP screening,...

    Authors: Zheng Guo, Nan Ma, Yixuan Wu, Hua Yuan, Wanjun Luo, Lingkong Zeng, Hong Jie and Shilian Li
    Citation: BMC Ophthalmology 2021 21:258
    Content type: Research Published on:

  13. To evaluate the necessity of cycloplegia for epidemiological studies of refraction in Chinese young adults (aged 17–22 years) with dark irises, and to compare the cycloplegic effects of 1% cyclopentolate and 0...

    Authors: Ruxia Pei, Zhuzhu Liu, Hua Rong, Liqiong Zhao, Bei Du, Na Jin, Hongmei Zhang, Biying Wang, Yi Pang and Ruihua Wei
    Citation: BMC Ophthalmology 2021 21:256
    Content type: Research article Published on:

  14. Previous studies have demonstrated that strabismus amblyopia can result in markedly brain function alterations. However, the differences in spontaneous brain activities of strabismus amblyopia (SA) patients st...

    Authors: Shuang Zhang, Gui-Ping Gao, Wen-Qing Shi, Biao Li, Qi Lin, Hui-Ye Shu and Yi Shao
    Citation: BMC Ophthalmology 2021 21:255
    Content type: Research Published on:

  17. To describe the longitudinal changes in retinal neovascularization elsewhere (NVE) as observed on optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR) treated by panretin...

    Authors: H. E. Feng, Y. U. Weihong and Fangtian Dong
    Citation: BMC Ophthalmology 2021 21:252
    Content type: Research Published on:

  19. The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymo...

    Authors: Ine Lambert, Giuseppe Fasolino, Gil Awada, Robert Kuijpers, Marcel ten Tusscher and Bart Neyns
    Citation: BMC Ophthalmology 2021 21:250
    Content type: Case report Published on:

  20. ALG3-CDG is a rare autosomal recessive disease. It is characterized by deficiency of alpha-1,3-mannosyltransferase caused by pathogenic variants in the ALG3 gene. Patients manifest with severe neurologic, cardiac...

    Authors: Martina Farolfi, Anna Cechova, Nina Ondruskova, Jana Zidkova, Bohdan Kousal, Hana Hansikova, Tomas Honzik and Petra Liskova
    Citation: BMC Ophthalmology 2021 21:249
    Content type: Research Published on:

  21. Eye injury is a serious worldwide public health problem that may cause blindness. In children, blindness has functional impact and psychosocial implications. As indicated in many worldwide studies, identificat...

    Authors: Valeria D’Antone, Diana Cristina Palencia Flórez, Claudia Juliana Lopez García, Flor De María Cáceres Manrique and Nahyr López Barbosa
    Citation: BMC Ophthalmology 2021 21:248
    Content type: Research Published on:

  22. No studies have been reported on the efficacy and safety of long-term (≥12 months) use of topical tacrolimus for refractory ocular surface inflammation in pediatric patients.

    Authors: Kyungmin Koh, Ikhyun Jun, Tae-im Kim, Eung Kweon Kim and Kyoung Yul Seo
    Citation: BMC Ophthalmology 2021 21:247
    Content type: Research Published on:

  24. We aimed to evaluate the efficacy and safety of phacoemulsification with intravitreal 3 mg triamcinolone acetonide injection in preventing postoperative inflammation and complications in patients with non-infe...

    Authors: Yan Ren, Shufang Du, Dongping Zheng, Yanyun Shi, Luping Pan and Hua Yan
    Citation: BMC Ophthalmology 2021 21:245
    Content type: Research Published on:

  26. To evaluate alterations in the serum concentrations of vascular endothelial growth factor (VEGF) and netrin-1 after intravitreal bevacizumab (BCZ) injection for the treatment of diabetic macular edema (DME).

    Authors: Murat Okutucu, Hüseyin Fındık, Mehmet Gökhan Aslan and Medeni Arpa
    Citation: BMC Ophthalmology 2021 21:243
    Content type: Research Published on:

  27. Choroidal osteoma is a benign intraocular tumor that can increase risk of developing choroidal neovascularization. The visual prognosis is influenced by the tumor location, decalcification status, overlying RP...

    Authors: Yun Zhang, Jia Fang, Shixin Zhao, Xiangjun She, Jun Wang and Lijun Shen
    Citation: BMC Ophthalmology 2021 21:242
    Content type: Case report Published on:

  28. The effect of various reduced doses of verteporfin photodynamic therapy (PDT) on choroidal blood flow in chronic central serous chorioretinopathy (CSC) remains unclear. Therefore, this study aimed to evaluate ...

    Authors: Shun Kumashiro, Seiji Takagi, Takashi Itokawa, Akiko Tajima, Tatsuhiko Kobayashi and Yuichi Hori
    Citation: BMC Ophthalmology 2021 21:241
    Content type: Research Published on:

  29. Myotonic dystrophy is an inherited disease characterized by progressive muscle weakness and myotonia. It is a multisystemic disorder that affects different parts of the body, including the eye. Dysfunction of ...

    Authors: Eric Kirkegaard-Biosca, Mònica Berges-Marti, Brahim Azarfane, Esther Cilveti, Laura Distefano and Jose García-Arumí
    Citation: BMC Ophthalmology 2021 21:240
    Content type: Case report Published on:

  30. Bietti crystalline dystrophy (BCD) is an autosomal recessive genetic disorder that causes progressive vision loss. Here, 12 patients were followed up for 1–5 years with fundus fluorescein angiography (FFA) to ...

    Authors: Shengjuan Zhang, Lifei Wang, Zhiqiang Liu, Huijing Sun, Qian Li, Chen Xing, Zhe Xiao and Xiaoyan Peng
    Citation: BMC Ophthalmology 2021 21:239
    Content type: Research article Published on:

  31. To compare quantitative visual tests, such as visual acuity, contrast sensitivity, and color vision tests in patients with primary open-angle glaucoma (POAG) patients according to three different light systems...

    Authors: Sang Woo Kim, YoungWook Go, Sang-Ook Kang and Chang Kyu Lee
    Citation: BMC Ophthalmology 2021 21:238
    Content type: Research Published on:

  33. We aimed to validate the predictive performance of the DIGIROP-Birth model for identifying treatment-requiring retinopathy of prematurity (TR-ROP) in Chinese preterm infants to evaluate its generalizability ac...

    Authors: Sizhe Chen, Rong Wu, He Chen, Wenbei Ma, Shaolin Du, Chao Li, Xiaohe Lu and Songfu Feng
    Citation: BMC Ophthalmology 2021 21:236
    Content type: Research Published on:

  34. Recently, we found that maximal medial rectus recession and lateral rectus resection in patients with complete lateral rectus paralysis resulted in a partial restoration of abduction. In an attempt to understa...

    Authors: Qing Xia, Xiangtian Ling, Zhonghao Wang, Tao Shen, Minghao Chen, Danyi Mao, Xinqi Ma, Jie Ning, Han Zhang, Dongli Chen, Qiong Gu, Huangxuan Shen and Jianhua Yan
    Citation: BMC Ophthalmology 2021 21:235
    Content type: Research Published on:

  36. This study aims to evaluate choroidal thickness (CT), retinal thickness, ganglion cell-inner plexiform layer (GCIPL), and retinal nerve fiber layer (RNFL) structures in psoriasis patients using optical coheren...

    Authors: Asena Keles Sahin, Fatma Etgü and Aslihan Uzun
    Citation: BMC Ophthalmology 2021 21:233
    Content type: Research Published on:

  38. Intraocular lens (IOL) calculation using traditional formulas for post-corneal refractive surgery eyes can yield inaccurate results. This study aimed to compare the clinical accuracy of the newly developed Zha...

    Authors: Jun Zhang, Jie Shao, Li Zheng, Ye Shen and Xia Zhao
    Citation: BMC Ophthalmology 2021 21:231
    Content type: Research Published on:

  41. Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we e...

    Authors: William Greig Mitchell, Edward Christopher Dee and Leo Anthony Celi
    Citation: BMC Ophthalmology 2021 21:228
    Content type: Correspondence Published on:

  43. Glaucoma is a leading cause of global blindness, especially preventable blindness. The increased prevalence of glaucoma has led to a growing demand for newer, safer, more rapid, and simpler treatments for the ...

    Authors: Noa Kapelushnik, Ari Leshno, Reut Singer, Ruth Huna-Baron, Yaniv Barkana and Alon Skaat
    Citation: BMC Ophthalmology 2021 21:226
    Content type: Research Published on:

  45. Filamentous fungi are ubiquitous in plants, water, and soil. The predominant fungi that infect the human cornea include Fusarium and Aspergillus species. The onset of fungal endophthalmitis is indolent, and typic...

    Authors: Yusuke Mitsuoka, Takeshi Soma, Kazuichi Maruyama and Kohji Nishida
    Citation: BMC Ophthalmology 2021 21:224
    Content type: Case report Published on:

  46. Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical co...

    Authors: Santiago Delgado-Tirado, Alberto López-Miguel, Yazmin Báez-Peralta, Lucía González-Buendía, Itziar Fernández, Jorge L. Alió, Miguel J. Maldonado and Rosa M. Coco-Martín
    Citation: BMC Ophthalmology 2021 21:223
    Content type: Research Published on:

  48. To investigate the changes in retinal nerve fiber layer thickness and macular blood flow density during the preclinical stage of diabetic retinopathy and their relationship with blood glucose.

    Authors: Hui Li, Xiaobing Yu, Bodi Zheng, Shan Ding, Zhongqing Mu and Lixin Guo
    Citation: BMC Ophthalmology 2021 21:220
    Content type: Research article Published on:

  49. The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients’ quality of life. No published studies on the epidemiology of dry eyes hav...

    Authors: Sarah Alkabbani, Lakshmanan Jeyaseelan, Anupama P. Rao, Sandeep P. Thakur and Pramod T. Warhekar
    Citation: BMC Ophthalmology 2021 21:219
    Content type: Research Published on:
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