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  1. The signaling pathway of epithelial to mesenchymal transition (EMT) is regulated by c-Src kinase in many cells. The purpose of this study was to investigate the effects of c-Src kinase on EMT of human lens epi...

    Authors: Xingyu Li, Fang Wang, Meixia Ren, Minjuan Du and Jian Zhou
    Citation: BMC Ophthalmology 2019 19:219
    Content type: Research article Published on:

  2. Traumatic optic neuropathy (TON) is a form of optic nerve injury that occurs secondary to trauma and is etiologically associated with acute axonal loss with severe vision loss. Here, we reported longitudinal c...

    Authors: Won June Lee, Eun Hee Hong, Hae Min Park and Han Woong Lim
    Citation: BMC Ophthalmology 2019 19:216
    Content type: Case report Published on:

  3. To evaluate choroidal vascularity index (CVI) in eyes with internal carotid artery (ICA) stenosis using binarization tool in enhanced depth images scanned by spectral domain optical coherence tomography.

    Authors: Shuang Li, Xuqiang Lang, Wei Wang, Yang Yang, Jingjing Wang, Hongyang Li, Yanling Wang and Kang Wang
    Citation: BMC Ophthalmology 2019 19:215
    Content type: Research article Published on:

  4. The common presence of human leukocyte antigen (HLA)-DRB1*04 in Vogt-Koyanagi-Harada (VKH) disease is well known. The aim of this study was to investigate the relationship between visual prognosis and HLA-DRB1...

    Authors: Norihiko Misawa, Mizuki Tagami, Takeya Kohno and Shigeru Honda
    Citation: BMC Ophthalmology 2019 19:214
    Content type: Research article Published on:

  7. This study aims to optimize the therapeutic regimen for refractory obstructive meibomian gland dysfunction (o-MGD) patients by combining intraductal meibomian gland probing (MGP) and intense pulsed light (IPL)...

    Authors: Xiaodan Huang, Qiyu Qin, Linping Wang, Jiao Zheng, Lin Lin and Xiuming Jin
    Citation: BMC Ophthalmology 2019 19:211
    Content type: Research article Published on:

  8. Uveal effusion syndrome is a rare entity of idiopathic exudative detachments of uveal tissues and retina. Medical treatments with systemic steroids and antimetabolites have been tried but with variable results...

    Authors: Anadi Khatri, Sweta Singh, Kriti Joshi and Muna Kharel
    Citation: BMC Ophthalmology 2019 19:210
    Content type: Case report Published on:

  9. Crouzon syndrome (CS), which results from fibroblast growth factor receptor 2 mutations, is associated with craniosynostosis, exophthalmos, and other symptoms. Herein, we report the genetic abnormalities detec...

    Authors: Ji Yang, Tao Tao, Hai Liu and Zhu-Lin Hu
    Citation: BMC Ophthalmology 2019 19:209
    Content type: Case report Published on:

  10. Opacification of hydrophobic and hydrophilic intraocular lenses (IOLs) has been reported. Herein, we report a case of spontaneous resolution of opacification following acute clouding of a trifocal IOL, which c...

    Authors: Tao Zhang, Shaowei Li, Chang Liu, Ruihua Zhao, Chenghe Chang and Na Han
    Citation: BMC Ophthalmology 2019 19:208
    Content type: Case report Published on:

  12. Real-world data (RWD) has been a valuable addition to the scientific literature regarding treatment pathways, clinical outcomes and characteristics of patients with retinal diseases in recent years. Registries...

    Authors: Vincent Daien, Bora M. Eldem, James S. Talks, Jean-Francois Korobelnik, Paul Mitchell, Robert P. Finger, Taiji Sakamoto, Tien Yin Wong, Obaro Evuarherhe, Gemma Carter and Joao Carrasco
    Citation: BMC Ophthalmology 2019 19:206
    Content type: Research article Published on:

  13. To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols.

    Authors: Isabel Rodríguez-Pérez, Juan Gros-Otero, Miguel A. Teus, Rafael Cañones and Montserrat García-González
    Citation: BMC Ophthalmology 2019 19:205
    Content type: Research article Published on:

  14. The metabolic activity of retina is higher than other human tissues and is crucial to the vision. Cynomolgus macaques is widely used in ophthalmic disease research. The evaluation and comparison of macular and...

    Authors: Jingyi Peng, Liuxueying Zhong, Li Ma, Jiayi Jin, Yongxin Zheng and Chenjin Jin
    Citation: BMC Ophthalmology 2019 19:204
    Content type: Research article Published on:

  17. To document the visual acuity, spectral domain optical coherence tomography (SD-OCT) findings and prognosis in10 eyes of 6 patients with foveal damage from solar retinopathy in 1 year.

    Authors: Marwa Mahmoud Abdellah, Engy Mohammed Mostafa, Mohamed Abdelatif Anber, Islam Saad El Saman and Mohammed Ezz Eldawla
    Citation: BMC Ophthalmology 2019 19:201
    Content type: Research article Published on:

  18. To compare the reoperation rate in patients with vitreous hemorrhage (VH) secondary to proliferative diabetic retinopathy (PDR) with or without preoperative intravitreal bevacizumab (IVB).

    Authors: Xuting Hu, Qintuo Pan, Jingwei Zheng, Zongming Song and Zongduan Zhang
    Citation: BMC Ophthalmology 2019 19:200
    Content type: Research article Published on:

  19. To report the successful treatment of ocular toxoplasmosis and present the use of multimodal imaging to describe the changes in ocular toxoplasmic lesions subsequent to treatment.

    Authors: Joong Hyun Park, Sang-Yoon Lee and Eun Kyoung Lee
    Citation: BMC Ophthalmology 2019 19:199
    Content type: Case report Published on:

  22. To evaluate the results of unilateral inferior oblique anterior transposition (IOAT) for markedly asymmetric dissociated vertical deviation (DVD) combined with inferior oblique over-action (IOOA).

    Authors: Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng and Li-Wei Zhu
    Citation: BMC Ophthalmology 2019 19:196
    Content type: Research article Published on:

  23. The subconjunctival anesthesia with local anesthetics is considered as a low-risk procedure allowing ocular surgery without serious complications typical for retro- or parabulbar anesthesia, especially in pati...

    Authors: Katharina Knoll, Kristine Chobanyan-Jürgens, Dirk O. Stichtenoth, Ingo Roland Volkmann, Katerina Hufendiek and Carsten Framme
    Citation: BMC Ophthalmology 2019 19:195
    Content type: Case report Published on:

  24. To investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in patients with diabetic macular edema (DME) treated monthly with ranibizumab.

    Authors: Yuxiang Hu, Yi Cheng, Xiaoxuan Xu, Bo Yang, Feng Mei, Qiong Zhou, Li Yan, Jun Wang and Xiaorong Wu
    Citation: BMC Ophthalmology 2019 19:194
    Content type: Research article Published on:

  25. In the recently published article entitled “Ocular ultrasound versus MRI in the detection of extrascleral extension in a patient with choroidal melanoma” Jacobsen et al. describe a case in which a hyper-intens...

    Authors: M. G. Jaarsma-Coes, T. A. Ferreira, G. P. M. Luyten and J. W. M. Beenakker
    Citation: BMC Ophthalmology 2019 19:193
    Content type: Correspondence Published on:

    The original article was published in BMC Ophthalmology 2018 18:320

  26. A patient’s perception of how their glaucoma is managed will influence both adherence to their medication and outcome measures such as quality of life.

    Authors: Alison Fraenkel, Graham A. Lee, Stephen J Vincent, Roslyn A. Vincent, Rupert R. A. Bourne and Peter Shah
    Citation: BMC Ophthalmology 2019 19:192
    Content type: Research article Published on:

  27. To investigate the efficacy and safety of repeated phototherapeutic keratectomies (PTKs) during long-term treatment for corneal dystrophy (CD) in a Chinese pedigree carrying the R124L mutation in TGFBI.

    Authors: Li Zeng, Jing Zhao, Yingjun Chen, Jianmin Shang, Aruma Aruma and Xingtao Zhou
    Citation: BMC Ophthalmology 2019 19:191
    Content type: Research article Published on:

  29. Severe Retinopathy of Prematurity (ROP) is a serious vasoproliferative disorder that can affect extremely premature infants. It continues to be one of the most important preventable causes of blindness in chil...

    Authors: Mohammad T. Akkawi, Mohammad M. Shehadeh, Amjaad N. Abu Shams, Doaa M. Al-Hardan, Lara J. Omar, Omar H. Almahmoud and Jamal A. S. Qaddumi
    Citation: BMC Ophthalmology 2019 19:189
    Content type: Research article Published on:

  30. To evaluate the correlating and predicting factors of visual outcome after implantation of newly developed diffractive quadrifocal intraocular lens (IOL).

    Authors: Chia-Yi Lee, Jing-Yang Huang, Chi-Chin Sun, Shun-Fa Yang, Hung-Chi Chen and Hung-Yu Lin
    Citation: BMC Ophthalmology 2019 19:188
    Content type: Research article Published on:

  31. To evaluate the clinical outcomes of extended depth of focus (EDOF) and monofocal intraocular lenses (IOLs) that share identical aspheric platform and compare their visual acuity tolerance to postoperative ref...

    Authors: Hyeck-Soo Son, Seong Ho Kim, Gerd U. Auffarth and Chul Young Choi
    Citation: BMC Ophthalmology 2019 19:187
    Content type: Research article Published on:

  34. With the diabetes mellitus (DM) prevalence increasing annually, the human grading of retinal images to evaluate DR has posed a substantial burden worldwide. SmartEye is a recently developed fundus image proces...

    Authors: Yi Xu, Yongyi Wang, Bin Liu, Lin Tang, Liangqing Lv, Xin Ke, Saiguang Ling, Lina Lu and Haidong Zou
    Citation: BMC Ophthalmology 2019 19:184
    Content type: Research article Published on:

  35. To evaluate the efficacy of epiretinal membrane removal in patients with good best-corrected visual acuity (BCVA) for improving visual function and quality of life (QOL).

    Authors: Hiroyuki Nakashizuka, Yorihisa Kitagawa, Yu Wakatsuki, Koji Tanaka, Koichi Furuya, Takayuki Hattori, Ryusaburo Mori and Hiroyuki Shimada
    Citation: BMC Ophthalmology 2019 19:183
    Content type: Research article Published on:

  36. To compare and correlate anterior segment measurements of myopic eyes implanted with Implantable Collamer lens (ICL V4c) by using anterior segment optical coherence tomography (AS-OCT), Pentacam and ultrasound...

    Authors: Ting Wan, Houfa Yin, Yi Yang, Fang Wu, Zhiyi Wu and Yabo Yang
    Citation: BMC Ophthalmology 2019 19:182
    Content type: Research article Published on:

  38. Undetected vision problems is an important cause of reduced academic achievement, performance in everyday life and self-esteem. This receives little attention in national health care services in Norway even th...

    Authors: Helle K. Falkenberg, Trine Langaas and Ellen Svarverud
    Citation: BMC Ophthalmology 2019 19:180
    Content type: Research article Published on:

  39. Vogt–Koyanagi–Harada (VKH) disease is a T-cell-mediated autoimmune disorder characterized by bilateral granulomatous panuveitis with various systemic manifestations. Although VKH disease rarely occurs in the p...

    Authors: Atsuko Katsuyama, Sentaro Kusuhara, Hiroyuki Awano, Hiroaki Nagase, Wataru Matsumiya and Makoto Nakamura
    Citation: BMC Ophthalmology 2019 19:179
    Content type: Case report Published on:

  41. In this analysis, we aimed to systematically compare the complications which were associated with femtosecond laser-assisted cataract surgery (FLACS) versus the conventional phacoemulsification surgery (CPE).

    Authors: Jinhua Wang, Fanfan Su, Yong Wang, Yao Chen, Qiao Chen and Fen Li
    Citation: BMC Ophthalmology 2019 19:177
    Content type: Research article Published on:

  42. This report describes a case in which hyperopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK) was performed following small incision lenticule extraction (SMILE) lenticule in situ implantation.

    Authors: Jing Zhao, Jianmin Shang, Lingling Niu, Haipeng Xu, Dong Yang, Yu Zhao, Dan Fu and Xingtao Zhou
    Citation: BMC Ophthalmology 2019 19:176
    Content type: Case report Published on:

  43. To assess the relationship between different indications for trans pars plana vitrectomies (PPV’s) and the intraocular pressure (IOP), and the effect of multiple PPV’s on the IOP. We also examined whether ther...

    Authors: Hrvoje Kovacic, Roger C. W. Wolfs, Emine Kılıç and Wishal D. Ramdas
    Citation: BMC Ophthalmology 2019 19:175
    Content type: Research article Published on:

  44. A patient’s health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark.

    Authors: Sofie Jandorf, Marie Krogh Nielsen, Kristine Sørensen and Torben Lykke Sørensen
    Citation: BMC Ophthalmology 2019 19:174
    Content type: Research article Published on:

  46. To evaluate corneal biomechanical properties by the Ocular Response Analyzer (ORA) in non keratoconic patients underwent penetrating keratoplasty (PK).

    Authors: Mohamed Samy Abd Elaziz, Hoda Mohamed Elsobky, Adel Galal Zaky, Eslam Ahmed Maher Hassan and Mahmoud Tawfik KhalafAllah
    Citation: BMC Ophthalmology 2019 19:172
    Content type: Research article Published on:

  47. To investigate the area of foveal avascular zone (FAZ) and macular vessel density (VD) after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography (OCTA).

    Authors: Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Tsutomu Yamashita, Tsuyoshi Yoneda, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Goro Maehara and Kiyoshi Yaoeda
    Citation: BMC Ophthalmology 2019 19:171
    Content type: Research article Published on:

  50. Age-related macular degeneration (AMD) is the primary cause of blindness and severe vision loss in developed countries and is responsible for 8.7% of blindness globally. Ultraviolet radiation can induce DNA br...

    Authors: Jiunn-Liang Chen, Chun-Tzu Hung, Joseph Jordan Keller, Hsien-Chung Lin and Yu-Jen Wu
    Citation: BMC Ophthalmology 2019 19:168
    Content type: Research article Published on:
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