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  1. To investigate the influence of scan distance on retinal boundary detection errors (RBDEs) and retinal thickness measurements by spectral domain optical coherence tomography (SD-OCT).

    Authors: Boglárka Enikő Varga, Erika Tátrai, Delia Cabrera DeBuc and Gábor Márk Somfai
    Citation: BMC Ophthalmology 2014 14:148
    Content type: Research article Published on:

  2. To evaluate the role of plasma total homocysteine (tHcy) and homozygosity for the thermolabile variant of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype in the risk of retinal vein occlusion (R...

    Authors: Dan Li, Minwen Zhou, Xiaoyan Peng and Huiyu Sun
    Citation: BMC Ophthalmology 2014 14:147
    Content type: Research article Published on:

  3. Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder involving aberrant proliferation of multiple tissues of neural crest origin. Retinal vascular alterations in NF1 have rarely been reported in th...

    Authors: Solmaz Abdolrahimzadeh, Lorenzo Felli, Domenica Carmen Piraino, Roberto Mollo, Stefano Calvieri and Santi Maria Recupero
    Citation: BMC Ophthalmology 2014 14:146
    Content type: Research article Published on:

  4. We evaluated subfoveal choroidal thickness measured with two different forms of optical coherence tomography (OCT), enhanced-depth imaging (EDI) and swept-source (SS) OCT, in central serous chorioretinopathy (...

    Authors: Ferdiriva Hamzah, Ari Shinojima, Ryusaburo Mori and Mitsuko Yuzawa
    Citation: BMC Ophthalmology 2014 14:145
    Content type: Research article Published on:

  5. P21 is one kind of cyclin-dependent kinase inhibitor that can prevent cells from going through the G1/S phase checkpoint and inhibit cell proliferation. Proliferative vitreoretinopathy (PVR) is a proliferative...

    Authors: Ying Wang, Zhigang Yuan, Caiyun You, Jindong Han, Haiyan Li, Zhuhong Zhang and Hua Yan
    Citation: BMC Ophthalmology 2014 14:144
    Content type: Research article Published on:

  7. In clinical settings, bacterial infections are usually diagnosed by isolation of colonies after laboratory cultivation followed by species identification with biochemical tests. However, biochemical tests resu...

    Authors: Fumika Hotta, Hiroshi Eguchi, Takeshi Naito, Yoshinori Mitamura, Kohei Kusujima and Tomomi Kuwahara
    Citation: BMC Ophthalmology 2014 14:142
    Content type: Case report Published on:

  9. Growth differentiation factor 6 (GDF6) has been reported to be a novel disease gene for age-related macular degeneration (AMD) in Caucasians. This study aimed to investigate whether rs6982567 was associated with...

    Authors: Yuying Ji, Xiongze Zhang, Kunfang Wu, Yu Su, Meng Li, Chengguo Zuo and Feng Wen
    Citation: BMC Ophthalmology 2014 14:140
    Content type: Research article Published on:

  10. The impact of strabismus on visual function, self-image, self-esteem, and social interactions might decrease health-related quality of life (HRQoL). This study aimed to evaluate the psychometric properties and...

    Authors: Zonghua Wang, Hui Ren, Rosemary Frey, Yang Liu, Deborah Raphael, Wei Bian and Xianyuan Wang
    Citation: BMC Ophthalmology 2014 14:139
    Content type: Research article Published on:

  11. The study aims to survey longstanding funduscopic and functional outcomes of age-related macular degeneration (AMD) after ranibizumab treatment and verify the accuracy of a new method to compare the retinal th...

    Authors: Rosa M Coco, M Rosa Sanabria, Melissa Castrejon, M Isabel Lopez-Galvez, Laura Monje-Fernandez, Marta Fernandez-Munoz, Alejandro Anton, Lourdes de Juan-Marcos, Sonia Villaron-Alvarez and Itziar Fernandez
    Citation: BMC Ophthalmology 2014 14:138
    Content type: Research article Published on:

  13. Lateralization of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) is very important for successful repositioning. The directions of lying-down nystagmus (LDN) and head-bending nys...

    Authors: Jung-Hwan Oh, Sook-Keun Song, Jung Seok Lee, Jay Chol Choi, Sa-Yoon Kang and Ji-Hoon Kang
    Citation: BMC Ophthalmology 2014 14:136
    Content type: Research article Published on:

  14. The mechanism underlying focal choroidal excavation (FCE) remains largely unknown. We evaluated the sequential progression of FCE generation using enhanced depth imaging optical coherence tomography (EDI-OCT) ...

    Authors: Yuki Hashimoto, Wataru Saito, Kousuke Noda and Susumu Ishida
    Citation: BMC Ophthalmology 2014 14:135
    Content type: Case report Published on:

  15. Surgically induced astigmatism (SIA) was one of the factors that influences the desirable refractive outcome, and it was related to the length, type, location, structure of the incision and to the suture closu...

    Authors: Xing Du, Guiqiu Zhao, Qing Wang, Xian Yang, Ang Gao, Jing Lin, Qian Wang and Qiang Xu
    Citation: BMC Ophthalmology 2014 14:134
    Content type: Research article Published on:

  16. Phacolytic glaucoma is induced by lens protein or macrophages that have leaked through a macroscopically intact anterior lens capsule. Here, we report a case of phacolytic glaucoma with anterior lens capsule d...

    Authors: Woong-Sun Yoo, Byeong-Jae Kim, In-Young Chung, Seong-Wook Seo, Ji-Myong Yoo and Seong-Jae Kim
    Citation: BMC Ophthalmology 2014 14:133
    Content type: Case report Published on:

  17. Multiple evanescent white dot syndrome (MEWDS) is an acute and usually unilateral retinopathy that occurs predominantly in young adults. This report presents the outcomes of ganglion cell analysis (GCA) in MEWDS.

    Authors: Hideo Akiyama, Hirotaka Itakura, Danjie Li, Tomoyuki Kashima, Keisuke Nitta, Yukitoshi Shimoda, Ryo Mukai and Shoji Kishi
    Citation: BMC Ophthalmology 2014 14:132
    Content type: Case report Published on:

  18. Posterior capsule opacification (PCO) is the most common post-operative complication associated with cataract surgery and is mostly treated with Nd:YAG laser capsulotomy. Here, we demonstrate the use of high-r...

    Authors: Gregor Hawlina, Darko Perovšek, Brigita Drnovšek-Olup, Janez Možina and Peter Gregorčič
    Citation: BMC Ophthalmology 2014 14:131
    Content type: Research article Published on:

  20. To determine if a method for irrigation and aspiration (I/A) during cataract surgery provides effective removal of ophthalmic viscoelastic device (OVD).

    Authors: Arisa Mitani, Takashi Suzuki, Yoshitaka Tasaka, Takahiro Uda, Yukako Hiramatsu, Shiro Kawasaki and Yuichi Ohashi
    Citation: BMC Ophthalmology 2014 14:129
    Content type: Research article Published on:

  21. Prolong sitting has been found associated with metabolic disorders. Little is known about the self-reported cataract status in general population of Taiwan, not to mention its relation to prolong sitting. We a...

    Authors: Ya-Hui Shih, Hsing-Yi Chang, Ming-Ing Lu and Baai-Shyun Hurng
    Citation: BMC Ophthalmology 2014 14:128
    Content type: Research article Published on:

  22. Elevated intraocular pressure (IOP) is a major risk factor for the development and/or progression of glaucoma, and a large diurnal IOP fluctuation has been identified as an independent risk factor of glaucoma ...

    Authors: Yoo Kyung Song, Chang-Kyu Lee, Jiwon Kim, Samin Hong, Chan Yun Kim and Gong Je Seong
    Citation: BMC Ophthalmology 2014 14:127
    Content type: Research article Published on:

  23. Detection of retinal lesions like micro-aneurysms and exudates are important for the clinical diagnosis of diabetes retinopathy. The traditional subjective judgments by clinicians are dependent on their experi...

    Authors: Huiqun Wu, Xiaofeng Zhang, Xingyun Geng, Jiancheng Dong and Guomin Zhou
    Citation: BMC Ophthalmology 2014 14:126
    Content type: Research article Published on:

  24. Nepal Pediatric Ocular Diseases Study is a three year longitudinal population based study. Here we present the baseline survey report which aims to investigate various risk factors associated with childhood oc...

    Authors: Srijana Adhikari, Mohan Krishna Shrestha, Kamala Adhikari, Nhukesh Maharjan and Ujjowala Devi Shrestha
    Citation: BMC Ophthalmology 2014 14:125
    Content type: Research article Published on:

  26. Intravitreal triamcinolone acetonide (IVTA) is an effective treatment for recalcitrant diabetic macular oedema (DMO). It has been shown to improve vision with benefits persisting up to five years. The most com...

    Authors: Roderick F O’Day, Daniel Barthelmes, Meidong Zhu, Tien Y Wong, Ian L McAllister, Jennifer J Arnold and Mark C Gillies
    Citation: BMC Ophthalmology 2014 14:123
    Content type: Research article Published on:

  27. The diurnal fluctuation of intraocular pressure may be relevant in glaucoma. The aim of this study was to find out whether the timing of diurnal fluctuation is stable over the years.

    Authors: Cord Huchzermeyer, Udo Reulbach, Folkert Horn, Robert Lämmer, Christian Y Mardin and Anselm GM Jünemann
    Citation: BMC Ophthalmology 2014 14:122
    Content type: Research article Published on:

  28. The purpose of the study was to measure the retinal venous pressure (RVP) in the eyes of primary open-angle glaucoma (POAG) patients and healthy subjects with and without a Flammer-Syndrome (FS).

    Authors: Lei Fang, Michael Baertschi and Maneli Mozaffarieh
    Citation: BMC Ophthalmology 2014 14:121
    Content type: Research article Published on:

  30. To determine the outcome of central retinal vein occlusion (CRVO) in pre-existing glaucoma and the predisposing factors of developing neovascular glaucoma (NVG).

    Authors: Hsi-Fu Chen, Min-Chi Chen, Chi-Chun Lai, Ling Yeung, Nan-Kai Wang, Henry Shen-Lih Chen, Wan-Chen Ku, Shiu-Chen Wu, Shirley H L Chang and Lan-Hsin Chuang
    Citation: BMC Ophthalmology 2014 14:119
    Content type: Research article Published on:

  31. To evaluate the use of optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness and visual field (VF) measurements in detecting disease progression in patients with early glaucoma.

    Authors: Kazuyuki Hirooka, Saki Manabe, Kaori Tenkumo, Eri Nitta, Shino Sato and Akitaka Tsujikawa
    Citation: BMC Ophthalmology 2014 14:118
    Content type: Research article Published on:

  33. The aims of this study were to determine the 5-year incidence of posterior capsule opacification (PCO) requiring Nd:YAG laser capsulotomy in a representative mixed cohort of cataract patients, to determine ris...

    Authors: Karin Sundelin, Nawaf Almarzouki, Yalda Soltanpour, Anne Petersen and Madeleine Zetterberg
    Citation: BMC Ophthalmology 2014 14:116
    Content type: Research article Published on:

  34. Visual impairment (VI) is associated with increased mortality and health factors such as depression and cardiovascular disease. Epidemiologic studies consistently show associations between sleep duration with ...

    Authors: Alberto R Ramos, Douglas M Wallace, Natasha J Williams, David Warren Spence, Seithikurippu Ratnas Pandi-Perumal, Ferdinand Zizi and Girardin Jean-Louis
    Citation: BMC Ophthalmology 2014 14:115
    Content type: Research article Published on:

  35. Macular hole results from a tractional force at the vitreo-retinal interface which is developed by modification and subsequent degeneration of the posterior precortical vitreous and the internal limiting membr...

    Authors: Tomohiro Okamoto, Hajime Shinoda, Toshihide Kurihara, Norihiro Nagai, Kazuo Tsubota and Yoko Ozawa
    Citation: BMC Ophthalmology 2014 14:114
    Content type: Case report Published on:

  36. It is difficult to identify glaucoma in myopic eyes because the configuration of the optic disc varies; yet it is important clinically. Here, we used laser speckle flowgraphy (LSFG) to measure mean blur rate (...

    Authors: Naoko Aizawa, Hiroshi Kunikata, Yukihiro Shiga, Yu Yokoyama, Kazuko Omodaka and Toru Nakazawa
    Citation: BMC Ophthalmology 2014 14:113
    Content type: Research article Published on:

  37. To report the rare occurrence of peripheral retinal sea-fan neovascularization in a patient with chronic rhegmatogenous retinal detachment and describe the surgical management.

    Authors: Ilias Georgalas, Theodore Paraskevopoulos, Chyssanthos Symmeonidis, Petros Petrou and Chryssanthi Koutsandrea
    Citation: BMC Ophthalmology 2014 14:112
    Content type: Case report Published on:

  38. Macular hole related retinal detachment is a common entity with poor surgical prognosis in highly myopic eyes. We describe the first case of spontaneous closure of a macular hole with complete retinal reattach...

    Authors: Jia Yu, Chunhui Jiang and Gezhi Xu
    Citation: BMC Ophthalmology 2014 14:111
    Content type: Case report Published on:

  39. Leukocoria is defined as a white reflection and its manifestation is symptomatic of several ocular pathologies, including retinoblastoma (Rb). Early detection of recurrent leukocoria is critical for improved p...

    Authors: Pablo Rivas-Perea, Erich Baker, Greg Hamerly and Bryan F Shaw
    Citation: BMC Ophthalmology 2014 14:110
    Content type: Technical advance Published on:

  40. Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye is rarely encountered.

    Authors: Chichua Alexander, Chichua George, Jikurashvili Tinatin, Saginashvili Maia, Mchedlishvili Maia and Pavlidis Mitrofanis
    Citation: BMC Ophthalmology 2014 14:109
    Content type: Case report Published on:

  41. To identify the genetic defects and investigate the possible mechanism of cataract genesis in a five-generation family with autosomal dominant congenital posterior polar cataracts.

    Authors: Xin-Yi Xia, Qiu-Yue Wu, Li-Mei An, Wei-Wei Li, Na Li, Tian-Fu Li, Cui Zhang, Ying-Xia Cui, Xiao-Jun Li and Chun-Yan Xue
    Citation: BMC Ophthalmology 2014 14:108
    Content type: Research article Published on:

  44. To characterize macular thickness (MT) changes in Leber’s hereditary optic neuropathy (LHON) patients by cirrus HD-optical coherence tomography (OCT), and to study the correlation between MT and best corrected...

    Authors: Yixin Zhang, Houbin Huang, Shihui Wei, Yan Gong, Hongyang Li, Yanli Dai, Shuo Zhao, Yingyun Wang and Hongxin Yan
    Citation: BMC Ophthalmology 2014 14:105
    Content type: Research article Published on:

  45. Luminance contrast sensitivity and colour vision are considered to have great predictive value in the evaluation of type 2 diabetic retinopathy. However, these two visual characteristics have seldom been inves...

    Authors: Luciana Cristina O Andrade, Givago S Souza, Eliza Maria CB Lacerda, Maira TST Nazima, Anderson R Rodrigues, Liudmila M Otero, Francineide PS Pena, Luiz Carlos L Silveira and Maria Izabel T Côrtes
    Citation: BMC Ophthalmology 2014 14:104
    Content type: Research article Published on:

  46. Macular edema is a common cause of visual loss at uveitic patients. The aim of our study was to investigate retinal and choroidal thickness at the macula in anterior (AU) and intermediate (IMU) uveitis and in ...

    Authors: Zsuzsanna Géhl, Kinga Kulcsár, Huba JM Kiss, János Németh, Otto A Maneschg and Miklós D Resch
    Citation: BMC Ophthalmology 2014 14:103
    Content type: Research article Published on:

  47. Netrin-1 has been reported to promote retinal neovascularization in oxygen-induced retinopathy (OIR). However, netrin-1 receptors, which may mediate netrin-1 action during retinal neovascularization, have not ...

    Authors: Dan Liu, Si-Qi Xiong, Lei Shang, Xiao-feng Tian, Jing Yang and Xiao-Bo Xia
    Citation: BMC Ophthalmology 2014 14:102
    Content type: Research article Published on:

  48. Retinal racemose hemangioma (RRH) is a rare congenital disorder that often co-occurs with other ocular complications. In this study, we present a case of RRH complicated with retinal vein obstruction in three ...

    Authors: Xue-jiao Qin, Chao Huang and Kun Lai
    Citation: BMC Ophthalmology 2014 14:101
    Content type: Case report Published on:

  49. At present there are no large scale nationally-representative studies from Sri Lanka on the prevalence and associations of Diabetic Retinopathy (DR). The present study aims to evaluate the prevalence and risk ...

    Authors: Prasad Katulanda, Priyanga Ranasinghe and Ranil Jayawardena
    Citation: BMC Ophthalmology 2014 14:100
    Content type: Research article Published on:

  50. This study assessed the barriers to sight impairment certification in the East London Borough of Tower Hamlets amongst patients attending the Diabetic Retinopathy Screening Service (DRSS).

    Authors: Rabia Bourkiza, Mala Subash, Dania Qatarneh, Joanna Dacosta, Catey Bunce and Tunde Peto
    Citation: BMC Ophthalmology 2014 14:99
    Content type: Research article Published on:
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