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  1. Content type: Research article

    Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) an...

    Authors: Verónica Castro-Navarro, Enrique Cervera-Taulet, Catalina Navarro-Palop, Clara Monferrer-Adsuara, Laura Hernández-Bel and Javier Montero-Hernández

    Citation: BMC Ophthalmology 2019 19:15

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  2. Content type: Research article

    To identify baseline patient characteristics associated with early clinically significant visual acuity (VA) improvements within 3 months of treatment initiation in ranibizumab-treated patients with retinal ve...

    Authors: W. Lloyd Clark, Mimi Liu, John Kitchens, Pin-wen Wang and Zdenka Haskova

    Citation: BMC Ophthalmology 2019 19:11

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  3. Content type: Case report

    Thyroid-associated orbitopathy (TAO) constitutes an immune-mediated inflammation of the orbital tissues of unclear etiopathogenesis. TAO is most prevalent in hyperthyroid patients with Graves’ disease (GD); ho...

    Authors: Ewa Cyranska-Chyrek, Michal Olejarz, Ewelina Szczepanek-Parulska, Piotr Stajgis, Anna Pioch and Marek Ruchala

    Citation: BMC Ophthalmology 2019 19:9

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  4. Content type: Research article

    Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implant...

    Authors: Lixiong Gao, Lijun Zhou, Chunyu Tian, Na Li, Weiyang Shao, Xiujun Peng and Qian Shi

    Citation: BMC Ophthalmology 2019 19:8

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  5. Content type: Case report

    Of the 10 patients with adenoviral type 54 keratoconjunctivitis examined at Nojima Hospital, 2 developed stellate keratitis and mutton-fat keratic precipitates (KPs) following acute symptoms.

    Authors: Kazuki Matsuura, Yuki Terasaka, Eiichi Uchio, Yusuke Saeki, Tsuguto Fujimoto, Nozomu Hanaoka, Dai Miyazaki and Yoshitsugu Inoue

    Citation: BMC Ophthalmology 2019 19:7

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  6. Content type: Research article

    The ability to extract depth from disparity may be hindered under fusional stress, as alignment of the eyes may be more difficult to maintain consistently. Therefore we aim to determine the effect of fusional ...

    Authors: Laurence P. Tidbury, Anna R. O’Connor and Sophie M. Wuerger

    Citation: BMC Ophthalmology 2019 19:6

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  7. Content type: Case report

    It has been previously reported that one copy of the variable number tandem repeat (VNTR) B alleles of the GPIbα gene increases the risk of non-arteritic ischaemic optic neuropathy (NAION) and the second eye i...

    Authors: Christina S. Lim, Ajoy Sarkar and Christopher Knapp

    Citation: BMC Ophthalmology 2019 19:5

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  8. Content type: Case report

    An occult foreign body may be retained in patient with small self-sealing wound and no decreased visual acuity without complete examination. Here we report a case of a retained occult ferrous iris foreign body...

    Authors: Zhitao Su, Houfa Yin, Panpan Ye, Xiaodan Huang, Li Zhang, Jianyun Fu and Xin Xie

    Citation: BMC Ophthalmology 2019 19:4

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  9. Content type: Research article

    To investigate the effect of scleral buckling (SB) on the morphology and density of human corneal endothelial cells (HCEC).

    Authors: Chia-Yi Lee, Hung-Ta Chen, Hung-Yu Lin, Hung-Chi Chen, Ling Yeung, Yih-Shiou Hwang, Kuan-Jen Chen, Wei-Chi Wu and Chi-Chun Lai

    Citation: BMC Ophthalmology 2019 19:3

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  10. Content type: Research article

    This study aimes to characterize the fundus structural changes in patients with nonarteritic anterior ischemic optic neuropathy (NAION) and the correlation between macular vessel density, retinal nerve fibre l...

    Authors: Hui Wang, Zhao-yang Meng, Song-guo Li, Jing-jing Wang, Jiao Sun and Hong-yang Li

    Citation: BMC Ophthalmology 2018 18:341

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  11. Content type: Research article

    This was an updated network meta-analysis (NMA) of anti-vascular endothelial growth factor (VEGF) agents and laser photocoagulation in patients with diabetic macular edema (DME). Unlike previous NMA that used ...

    Authors: Dominic Muston, Jean-Francois Korobelnik, Tim Reason, Neil Hawkins, Ismini Chatzitheofilou, Fay Ryan and Peter K. Kaiser

    Citation: BMC Ophthalmology 2018 18:340

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  12. Content type: Research article

    To assess a possible signal drift, noise and influences of electromagnetic radiation on the measurement behaviour of the Triggerfish® contact lens sensor, which might be mistaken as IOP fluctuations.

    Authors: Dieter Franz Rabensteiner, Jasmin Rabensteiner and Christoph Faschinger

    Citation: BMC Ophthalmology 2018 18:338

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  13. Content type: Research article

    Conventional corneal cross-linking is effective for retarding the progression of keratoconus. However the long-term efficacy and safety of accelerated (45 mW/cm2) transepithelial corneal cross-linking (ATE-CXL...

    Authors: Jinrong Huang, Yang Shen, Weijun Jian, Haipeng Xu, Meiyan Li, Jing Zhao, Xingtao Zhou and Hongfei Liao

    Citation: BMC Ophthalmology 2018 18:337

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  14. Content type: Research article

    Cornea protects the eye against natural and anthropogenic ultraviolet (UV) damage and mechanical injury. Corneal incisions produced by UV lasers in ophthalmic surgeries are often complicated by oxidative stres...

    Authors: Evgeni Yu. Zernii, Olga S. Gancharova, Veronika V. Tiulina, Andrey A. Zamyatnin Jr, Pavel P. Philippov, Viktoriia E. Baksheeva and Ivan I. Senin

    Citation: BMC Ophthalmology 2018 18:336

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  15. Content type: Case report

    External ophtalmomyiasis (EOM) is a zoonosis related to the presence of Oestrus ovis larvae at the ocular level in small ruminants (i.e. ovine, caprine). In humans, EOM is a rare cosmopolitan disorder, mostly des...

    Authors: Louise Basmaciyan, Pierre-Henry Gabrielle, Stéphane Valot, Marc Sautour, Jean-Christophe Buisson, Catherine Creuzot-Garcher and Frédéric Dalle

    Citation: BMC Ophthalmology 2018 18:335

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  16. Content type: Research article

    The optical density of the cornea can be evaluated quantitatively by “densitometry” using a rotating Scheimpflug camera. Densitometry allows evaluation of corneal opacity in the anterior segment of the eye by ...

    Authors: Sho Ishikawa, Naoko Kato and Masaru Takeuchi

    Citation: BMC Ophthalmology 2018 18:334

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  17. Content type: Research article

    To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world ...

    Authors: Polona Jaki Mekjavić, Bogdan Gregorčič, Cvetka Oberč and Slava Podgoršek

    Citation: BMC Ophthalmology 2018 18:333

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  18. Content type: Research article

    The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR).

    Authors: Takao Hirano, Akira Imai, Hirotsugu Kasamatsu, Shinji Kakihara, Yuichi Toriyama and Toshinori Murata

    Citation: BMC Ophthalmology 2018 18:332

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  19. Content type: Research article

    A substantial number of epidemiological studies have investigated the possible associations between sunlight exposure and Age-related Macular Degeneration (AMD), but the results from studies are inconsistent. ...

    Authors: Hongjie Zhou, Huina Zhang, Aiqing Yu and Jiajun Xie

    Citation: BMC Ophthalmology 2018 18:331

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  20. Content type: Research article

    Orbital vascular malformation often encircles normal tissue with ill-defined borders. It is easy to bleed during resection operation, making surgical treatment difficult and lesions hard to be removed complete...

    Authors: Tingting Lin, Limin Zhu and Yanjin He

    Citation: BMC Ophthalmology 2018 18:330

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  21. Content type: Research article

    To describe the effectiveness of combined pentagonal resection and inferior retractor plication (PR + IRP) based on the Hill’s procedure for the treatment of primary involutional lower eyelid entropion in the ...

    Authors: Janice J. C. Cheung, Carlos K. H. Wong and Leanne T. Y. Cheung

    Citation: BMC Ophthalmology 2018 18:329

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  22. Content type: Research article

    Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogeni...

    Authors: Alexios J. Aletras, Ioannis Trilivas, Maria-Elpida Christopoulou, Sotiria Drakouli, Constantine D. Georgakopoulos and Nikolaos Pharmakakis

    Citation: BMC Ophthalmology 2018 18:328

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  23. Content type: Research article

    To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA).

    Authors: Mengyang Li, Enzhong Jin, Chongya Dong, Chuan Zhang, Mingwei Zhao and Jinfeng Qu

    Citation: BMC Ophthalmology 2018 18:326

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  24. Content type: Research article

    To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous n...

    Authors: Hiroto Terasaki, Shozo Sonoda, Naoko Kakiuchi, Hideki Shiihara, Takehiro Yamashita and Taiji Sakamoto

    Citation: BMC Ophthalmology 2018 18:324

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  25. Content type: Case report

    Leber’s hereditary optic neuropathy (LHON) is a maternally inherited recessive disease rarely complicated with glaucoma. We conducted a clinical and genetic retrospective case series to describe three cases of...

    Authors: Yun-Hsuan Lin, Nan-Kai Wang, Ling Yeung, Chi-Chun Lai and Lan-Hsin Chuang

    Citation: BMC Ophthalmology 2018 18:323

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  26. Content type: Research article

    This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs).

    Authors: Emi Morimoto, Yoshiaki Shimada, Mitsuo Sugimoto, Tadashi Mizuguchi, Atsuhiro Tanikawa and Masayuki Horiguchi

    Citation: BMC Ophthalmology 2018 18:322

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  27. Content type: Research article

    Changes in retinal fluid patterns associated with circumscribed choroidal hemangioma (CCH) have not been investigated yet. A long-term follow-up study was performed to evaluate the changes of retinal fluid pat...

    Authors: Junwon Lee, Christopher Seungkyu Lee, Min Kim and Sung Chul Lee

    Citation: BMC Ophthalmology 2018 18:321

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  28. Content type: Case report

    Doyne honeycomb retinal dystrophy (DHRD)/malattia leventinese (ML) is a rare allelic condition with massive drusen in the posterior fundus caused by EFEMP1 gene mutation. Patients showed decreased vision when the...

    Authors: Kaiyan Zhang, Xuyang Sun, Yingying Chen, Qionglei Zhong, Lin Lin, Yuan Gao and Fanlin Hong

    Citation: BMC Ophthalmology 2018 18:318

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  29. Content type: Case report

    This report highlights a rare case of simultaneous bilateral blindness due to posterior ischemic optic neuropathy. Typically, ophthalmic involvement in giant cell arteritis is monocular or sequential ischemia ...

    Authors: Anas Mohammad Albarrak, Yousef Mohammad, Sajjad Hussain, Sufia Husain and Taim Muayqil

    Citation: BMC Ophthalmology 2018 18:317

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  30. Content type: Research article

    Ingrowth of newly formed blood and lymph vessels (angiogenesis) from the limbus region into the cornea can be treated successfully by subconjunctival application of antiangiogenic agents. Currently, there are ...

    Authors: Patrick R. Merz, Nina Röckel, Seda Ballikaya, Gerd U. Auffarth and Ingo Schmack

    Citation: BMC Ophthalmology 2018 18:316

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  31. Content type: Research article

    Despite the potential usefulness of optical coherence tomography angiography in retinal and optic disc conditions, the reliability of the imaging modality remains unclear. This study set out to measure the mic...

    Authors: Ching Wei Lim, Jun Cheng, Elton Lik Tong Tay, Hwei Yee Teo, Elizabeth Poh Ying Wong, Vernon Khet Yau Yong, Boon Ang Lim, Owen Kim Hee, Hon Tym Wong and Leonard Wei Leon Yip

    Citation: BMC Ophthalmology 2018 18:315

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  32. Content type: Research article

    The purpose of this study is to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections to treat cytomegalovirus retinitis in patients without human immunodeficien...

    Authors: Zhuyun Qian, Haili Li, Yong Tao and Wensheng Li

    Citation: BMC Ophthalmology 2018 18:314

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  33. Content type: Research article

    Patients with retinal diseases frequently complain of poor visual function even when visual acuity is relatively unaffected. This clinical finding has been attributed to deficits in contrast sensitivity (CS). ...

    Authors: Badr O. Alahmadi, Amro A. Omari, Maria Fernanda Abalem, Chris Andrews, Dana Schlegel, Kari H. Branham, Naheed W. Khan, Abigail Fahim and Thiran Jayasundera

    Citation: BMC Ophthalmology 2018 18:313

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  34. Content type: Case report

    Cystoid macular oedema (CMO) is an uncommon complication associated with hydroxychloroquine (HCQ) retinopathy threatening central vision. We report a patient with HCQ retinopathy and CMO, for which an intravit...

    Authors: Seong Joon Ahn, Jooyoung Joung, Sang Hyup Lee and Byung Ro Lee

    Citation: BMC Ophthalmology 2018 18:310

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