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  1. Content type: Research article

    The role of histone deacetylases 6 (HDAC6) has been elucidated in various neurodegenerative diseases. However, the effect of HDAC6 on retinal degenerative processes remains unknown. The aim of this study was t...

    Authors: Haihong Yuan, Hui Li, Ping Yu, Qichen Fan, Xuan Zhang, Wei Huang, Junyi Shen, Yongyao Cui and Wei Zhou

    Citation: BMC Ophthalmology 2018 18:300

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  2. Content type: Case report

    Granulomatosis with polyangiitis (GPA), a necrotizing granulomatous disease, very rarely involves the central nervous system (CNS), particularly the pituitary. Delayed treatment may cause permanent bilateral b...

    Authors: Xia Zhang, Bing Xing, Hui You, Huanwen Wu, Yong Zhong and Jin Ma

    Citation: BMC Ophthalmology 2018 18:299

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  3. Content type: Research article

    We aimed to analyze the differences in the prevalence of outer retinal tubulation (ORT) in neovascular age-related macular degeneration (AMD) treated with anti-vascular endothelial growth factor (anti-VEGF) ag...

    Authors: Attila Kovacs, Timea Kiss, Ferenc Rarosi, Gabor M. Somfai, Andrea Facsko and Rozsa Degi

    Citation: BMC Ophthalmology 2018 18:298

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  4. Content type: Research article

    Genetic studies have reported contradictory results on the association between the intercellular adhesion molecule-1 (ICAM-1) rs5498 polymorphism and diabetic retinopathy (DR) risk in type 2 diabetic patients. We...

    Authors: Zikang Xie and Hao Liang

    Citation: BMC Ophthalmology 2018 18:297

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  5. Content type: Research article

    To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic ...

    Authors: Hong-Ying Jin, Ting Wan, Xiao-Ning Yu, Fang Wu and Ke Yao

    Citation: BMC Ophthalmology 2018 18:295

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  6. Content type: Research article

    Cataract surgery with pseudophakic mini-monovision has lower out-of-pocket patient expense than premium multifocal intraocular lenses (IOL). The purpose of this study was to evaluate patient-reported satisfact...

    Authors: Debora Goetz Goldberg, Michael H. Goldberg, Riddhi Shah, Jane N. Meagher and Haresh Ailani

    Citation: BMC Ophthalmology 2018 18:293

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  7. Content type: Research article

    To identify novel biomarkers related to the pathogenesis of dry age-related macular degeneration (AMD), we adopted a human retinal pigment epithelial (RPE) cell culture model that mimics some features of dry A...

    Authors: Je-Hyun Baek, Daehan Lim, Kyu Hyung Park, Jae-Byoung Chae, Hyoik Jang, Jonghyun Lee and Hyewon Chung

    Citation: BMC Ophthalmology 2018 18:289

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  8. Content type: Research article

    To investigate thickness changes in the corneal epithelium and Bowman’s layer after overnight silicone hydrogel contact lens (CL) wear by using ultra-high resolution optical coherence tomography (UHROCT).

    Authors: Fan Lu, Aizhu Tao, Weiwei Tao, Xiran Zhuang and Meixiao Shen

    Citation: BMC Ophthalmology 2018 18:286

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  9. Content type: Research article

    The early diagnosis of cancer is of crucial importance and a key prognostic factor. Cancer-associated retinopathy (CAR) can be symptomatic prior to other manifestations directly related to malignant tumors. Th...

    Authors: Florence Hoogewoud, Pauline Butori, Philippe Blanche and Antoine P. Brézin

    Citation: BMC Ophthalmology 2018 18:285

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  10. Content type: Case report

    Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine g...

    Authors: Yasuhiro Iesato, Masaaki Tanaka, Masako Murata, Junya Kitahara, Takao Hirano, Taihei Kurenuma, Noriko Yoshida and Toshinori Murata

    Citation: BMC Ophthalmology 2018 18:284

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  11. Content type: Case report

    Giant cell arteritis (GCA) is a systemic vasculitis of medium and large-size vessels and can led to permanent visual loss in elderly patients. GCA is very rare among Asians. We report a Chinese patient present...

    Authors: Guohong Tian, Weimin Chen, Qian Chen, Min Wang, Guixian Zhao, Zhenxin Li and Jiong Zhang

    Citation: BMC Ophthalmology 2018 18:282

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  12. Content type: Research article

    A major obstacle that academic institutions face is the steep learning curve for cornea fellows initially learning to perform Descemet Stripping Endothelial Keratoplasty (DSEK). The purpose of this study is to...

    Authors: Jacquelyn Daubert, Terrence P. O’Brien, Eldad Adler and Oriel Spierer

    Citation: BMC Ophthalmology 2018 18:281

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  13. Content type: Research article

    Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat

    Citation: BMC Ophthalmology 2018 18:279

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  14. Content type: Case report

    Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especiall...

    Authors: Mário Luiz R. Monteiro, Kenzo Hokazono, Leonardo P. Cunha and Laurentino Biccas Neto

    Citation: BMC Ophthalmology 2018 18:278

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  15. Content type: Case report

    The present study reported a case of juxtapapillary retinal capillary hemangioma (JRCH) that was successfully treated by two sessions of full-fluence photodynamic treatment (PDT) with good visual outcome.

    Authors: Bainan Tong, Jun Xiao and Guanfang Su

    Citation: BMC Ophthalmology 2018 18:277

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  16. Content type: Review

    Toxic anterior segment syndrome (TASS) can be a rare complication of anterior segment surgery. Here we reviewed the most recent advances in the understanding of TASS.

    Authors: Choul Yong Park, Jimmy K. Lee and Roy S. Chuck

    Citation: BMC Ophthalmology 2018 18:276

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  17. Content type: Research article

    The purpose of this study is to discuss whether genetic variants (rs2230199, rs1047286, rs2230205, and rs2250656) in the C3 gene account for a significant risk of advanced AMD.

    Authors: Jun Zhang, Shuang Li, Shuqiong Hu, Jiguo Yu and Yi Xiang

    Citation: BMC Ophthalmology 2018 18:274

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  18. Content type: Research article

    Shielding and scattering effect of the smoke plume column ejected from the laser ablated material is a well-known phenomenon. Debris evacuation system of the excimer laser equipment removes these particles, bu...

    Authors: Csaba Szekrényesi, Huba Kiss, Tamás Filkorn and Zoltán Zsolt Nagy

    Citation: BMC Ophthalmology 2018 18:273

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  19. Content type: Case report

    Giant retinal tear is usually challenging among retinal detachment with recurrent rate up to 45%. Here we presented a case of giant retinal tear being treated by microincision vitrectomy and retinal tacks fixa...

    Authors: Yo-Chen Chang, Li-Yi Chiu, Tzu-En Kao, Wen-Hsin Cheng, Ting-An Chen and Wen-Chuan Wu

    Citation: BMC Ophthalmology 2018 18:272

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  20. Content type: Research article

    The membrane frizzled-related protein (MFRP) gene is involved in axial length (AL) regulation and MFRP mutations cause nanophthalmos; also, the hepatocyte growth factor (HGF) gene is reported to result in morphol...

    Authors: Shaolin Wang, Wenjuan Zhuang, Jianqing Ma, Manyun Xu, Shunyu Piao, Juan Hao, Wen Zhang, Hao Chi, Zhongqi Xue and Shaoping Ha

    Citation: BMC Ophthalmology 2018 18:271

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  21. Content type: Research article

    The aim was, first, to collect normative data of the optic nerve head and the peripapillary retinal nerve fibre layer (RNFL) thickness assessed with Cirrus SD-OCT, in healthy children in a population-based stu...

    Authors: Eva Larsson, Anna Molnar and Gerd Holmström

    Citation: BMC Ophthalmology 2018 18:270

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  22. Content type: Research article

    To compare different K readings in pseudophakic patients post-Descemet’s stripping automated endothelial keratoplasty (DSAEK) and evaluate corresponding prediction errors in intraocular lens (IOL) power calculati...

    Authors: Ke Xu, Hong Qi, Rongmei Peng, Gege Xiao, Jing Hong, Yansheng Hao and Boping Ma

    Citation: BMC Ophthalmology 2018 18:268

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  23. Content type: Case report

    We report a rare case of a woman with optic disk melanocytoma (ODMC) in conjunction with polypoidal choroidal vasculopathy (PCV). We also present, for the first time in literature, the clinical and morphologic...

    Authors: Alexandros Rouvas, Nikolaos S Gouliopoulos, Marilita M Moschos and Panagiotis Theodossiadis

    Citation: BMC Ophthalmology 2018 18:267

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  24. Content type: Case report

    Waardenburg syndrome (WS) is a very rare genetic disorder affecting the neural crest cells. Coexistence of branch retinal vein occlusion (BRVO) and branch retinal artery occlusion (BRAO) in the same eye is als...

    Authors: Eun Young Choi, Wungrak Choi and Christopher Seungkyu Lee

    Citation: BMC Ophthalmology 2018 18:266

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  25. Content type: Case report

    To demonstrate a full thickness macular hole (MH) development after vitrectomy (VT) for rhegmatogenous retinal detachment (RRD) and to investigate the possible disease mechanism with optical coherence tomograp...

    Authors: Hsin-Yu Yang and Chang-Sue Yang

    Citation: BMC Ophthalmology 2018 18:265

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  26. Content type: Case report

    Coats disease is a retinal disease characterized by exudative retinal detachment due to abnormal retinal blood vessels. Coats disease is generally treated using laser photocoagulation and cryotherapy to ablate...

    Authors: Michie Namba, Yusuke Shiode, Yuki Morizane, Shuhei Kimura, Mio Hosokawa, Shinichiro Doi, Shinji Toshima, Kosuke Takahashi, Mika Hosogi, Atsushi Fujiwara and Fumio Shiraga

    Citation: BMC Ophthalmology 2018 18:264

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  27. Content type: Research article

    International Task Force (ITF) guidelines established a grading scheme to support treatment of dry eye disease based on clinical signs and symptoms. The purpose of this study was to assess the impact of dry ey...

    Authors: Laurie Barber, Omid Khodai, Thomas Croley, Christopher Lievens, Stephen Montaquila, Jillian Ziemanski, Melissa McCart, Orsolya Lunacsek, Caroline Burk and Vaishali Patel

    Citation: BMC Ophthalmology 2018 18:260

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  28. Content type: Case report

    We recently reported that lamellar macular hole (LMH) with lamellar hole-associated epiretinal proliferation (LHEP) can be effectively treated by embedding the LHEP into the retinal cleavage to improve foveal ...

    Authors: Yusuke Shiode, Yuki Morizane, Kosuke Takahashi, Shuhei Kimura, Mio Hosokawa, Masayuki Hirano, Shinichiro Doi, Shinji Toshima, Mika Hosogi, Atsushi Fujiwara and Fumio Shiraga

    Citation: BMC Ophthalmology 2018 18:257

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  29. Content type: Case report

    Descemet’s membrane detachment (DMD) is a rare complication after ocular chemical injury and its pathogenesis remains unclear. In this study, we reported two cases of DMD with traction demonstrated on Anterior...

    Authors: Xiaoling Zhang, Vishal Jhanji and Haoyu Chen

    Citation: BMC Ophthalmology 2018 18:256

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