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  1. This study evaluated the effects of dexamethasone intravitreal implant on treatment-naïve branch retinal vein occlusion (BRVO)-induced macular edema (ME), and the risk factors for earlier repeated treatment.

    Authors: Yu-Te Huang, Chun-Ju Lin, Huan-Sheng Chen, Peng-Tai Tien, Chun-Ting Lai, Ning-Yi Hsia, Jane-Ming Lin, Wen-Lu Chen and Yi-Yu Tsai
    Citation: BMC Ophthalmology 2021 21:142
    Content type: Research article Published on:

  2. It is critical to monitor the optic disc’s vessel density using Optical coherence tomography angiography (OCTA) and evaluate its determinants. In the current study, we investigate the superficial vessel densit...

    Authors: Li-jun Zhou, Xiu-zhi Luo, Pei-yang Shen, Xin Li, Peng Su, Zhe Zhu, Shi-gang Yan, Xiang-bin Kong and Xiao-he Lu
    Citation: BMC Ophthalmology 2021 21:140
    Content type: Research article Published on:

  3. To report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno trabeculectomy. Specifically, this series focusses upon preservation of...

    Authors: Vipul Ramjiani, Hardeep-Singh Mudhar, Thomas Julian and Graham Auger
    Citation: BMC Ophthalmology 2021 21:138
    Content type: Research article Published on:

  5. The ultra-Orthodox Jewish community has a unique lifestyle including minimal outdoor activity and intense, prolonged nearby work, beginning at a very young age. Their prevalence of myopia is extremely high. Th...

    Authors: Sharon Armarnik, Maya Lavid, Sharon Blum, Tamara Wygnanski-Jaffe, David B. Granet and Michael Kinori
    Citation: BMC Ophthalmology 2021 21:136
    Content type: Research article Published on:

  7. Postoperative ocular imbalance is an important problem for orbital decompression surgery in thyroid eye disease (TED). The aim of this study was to evaluate the changes in unilateral ocular deviation and ducti...

    Authors: Jie Guo, Xiaofeng Li, Ruiqi Ma and Jiang Qian
    Citation: BMC Ophthalmology 2021 21:134
    Content type: Research article Published on:

  8. The purpose of the study was to investigate whether dynamic monocyte chemoattractant protein-1 (MCP-1) level might be as predictors of perceived pain during the first and second phacoemulsification eye surgeri...

    Authors: Feng Zhang, Jin-Hua Wang and Mei-Sheng Zhao
    Citation: BMC Ophthalmology 2021 21:133
    Content type: Research article Published on:

  9. We investigated structural injury patterns in the peripapillary retinal nerve fibre layer (p-RNFL) and ganglion cell inner plexiform layer (GCIPL) caused by ethambutol treatment.

    Authors: Wen-Yan Sheng, Ling-Ya Su, Wei Ge, Shuang-Qing Wu and Li-Wei Zhu
    Citation: BMC Ophthalmology 2021 21:132
    Content type: Research article Published on:

  10. Conjunctival autograft transplantation from superior conjunctiva is often chosen to lower the postoperative recurrence rate for pterygium treatment. However, inferior conjunctival autograft (ICA) might be take...

    Authors: Wenwei Li, Yaoyong Lou and Bin Wang
    Citation: BMC Ophthalmology 2021 21:131
    Content type: Research article Published on:

  12. To evaluate the efficacy and outcomes of one-way surgical technique for the treatment of vitreous hemorrhage post vitrectomy on proliferative diabetic retinopathy (PDR) patients.

    Authors: Qun Wang, Jie Zhao, Qing Xu, Cui Han, Baojie Hou and Yifei Huang
    Citation: BMC Ophthalmology 2021 21:129
    Content type: Research article Published on:

  13. The current practice for new-born eye examination by an Ophthalmologist in Malaysian hospitals is limited to only preterm new-borns, syndromic or ill infants. Healthy term new-borns are usually discharged with...

    Authors: Kenneth Teow Kheng Leong, Siti Nur Amira Abu Kassim, Jasvinjeet Kaur Sidhu, Zayani Zohari, Thivakar Sivalingam, Sunder Ramasamy, Safinaz Mohd Khialdin, Noraihan Mohd Nordin and Jamalia Rahmat
    Citation: BMC Ophthalmology 2021 21:128
    Content type: Research article Published on:

  14. Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle an...

    Authors: Giedre Pakuliene, Kirilas Zimarinas, Irena Nedzelskiene, Brent Siesky, Loreta Kuzmiene, Alon Harris and Ingrida Januleviciene
    Citation: BMC Ophthalmology 2021 21:127
    Content type: Research article Published on:

  15. Glistenings describe small, refractile microvacuoles that may arise within the intraocular lens (IOL) material and reduce the patients’ quality of vision. Lenses composed of hydrophobic acrylic material are pa...

    Authors: Tamer Tandogan, Gerd U. Auffarth, Hyeck-Soo Son, Patrick Merz, Chul Young Choi and Ramin Khoramnia
    Citation: BMC Ophthalmology 2021 21:126
    Content type: Research article Published on:

  16. Intraoperative floppy iris syndrome is a variant of the small pupil syndrome that has been observed during cataract surgery in some patients currently or previously treated with α1 adrenergic blockers. It is i...

    Authors: Umut Karaca, Engin Kaya, Onder Ayyildiz, Gokhan Ozge, Murat Kucukevcilioglu, Gulsah Usta and Fatih Mehmet Mutlu
    Citation: BMC Ophthalmology 2021 21:125
    Content type: Research article Published on:

  18. This study aimed at investigating: 1) the relationship between self-care agency and depression and anxiety; 2) the sociodemographic and clinical factors associated with depression and anxiety in patients with ...

    Authors: Bo Zhang, Qin Wang, Xuancan Zhang, Li Jiang, Lezhi Li and Bangshan Liu
    Citation: BMC Ophthalmology 2021 21:123
    Content type: Research article Published on:

  21. To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn op...

    Authors: Xiaofen Feng, Yan Nan, Jiandong Pan, Ruitao Zou, Lijun Shen and Feng Chen
    Citation: BMC Ophthalmology 2021 21:120
    Content type: Research article Published on:

  22. This paper fills a gap in the applied research field, for a local context, by addressing the topics of describing cataract surgery’ clinical outcomes; quality of life (QoL); and costs of the patients treated a...

    Authors: Lara Queirós, Patrícia Redondo, M. França, Sérgio Estrela Silva, Pedro Borges, António Benevides de Melo, Nuno Pereira, Paulo Freitas da Costa, Nazaré Carvalho, Marina Borges, Isabel Sequeira, Francisco Nuno Rocha Gonçalves and José Lemos
    Citation: BMC Ophthalmology 2021 21:119
    Content type: Research article Published on:

  24. To investigate the aetiopathology of recurrent epiphora or stickiness after dacryocystorhinostomy (DCR) surgery, identifiable on dacryocystography (DCG), and to assess the success rates of secondary corrective...

    Authors: Hannah M. Timlin, Swan Kang, Kailun Jiang and Daniel G. Ezra
    Citation: BMC Ophthalmology 2021 21:117
    Content type: Research article Published on:

  27. The aim of this study was to evaluate the effects of systemic parameters, laboratory findings, oral parameters, and other ocular surface parameters on ocular surface epithelial damage in patients with primary ...

    Authors: Ji Eun Kim, Na Rae Kim, Hee Seung Chin, Kyoung Yul Seo, Tae-im Kim and Ji Won Jung
    Citation: BMC Ophthalmology 2021 21:114
    Content type: Research article Published on:

  29. To compare ocular and corneal inherent aberrations in the naked eyes of randomly selected children fitted with MiSight contact lenses (CL) for myopia control, versus children corrected with single-vision spect...

    Authors: Daniela Lopes-Ferreira, Alicia Ruiz-Pomeda, Belén Peréz-Sanchéz, António Queirós and César Villa-Collar
    Citation: BMC Ophthalmology 2021 21:112
    Content type: Research article Published on:

  31. Cataract surgeries can improve mental health outcomes. However, previous studies have not investigated whether the time interval between cataract surgeries for 2 eyes affects mental health outcomes.

    Authors: Chiun-Ho Hou, Ken-Jen Chen, Jiahn-Shing Lee, Ken-Kuo Lin and Christy Pu
    Citation: BMC Ophthalmology 2021 21:110
    Content type: Research article Published on:

  32. Treatment of recurrent retinal detachment (re-RD) following vitrectomy (post-gas/air tamponade and post-silicone oil removal) is challenging. Previously reported treatment is commonly revision pars plana vitre...

    Authors: Jun-Xing Bai, Xiao-Jian Zhang, An-Li Duan and Xiao-Yan Peng
    Citation: BMC Ophthalmology 2021 21:109
    Content type: Research article Published on:

  33. This study aims to compare the levels of intraocular cytokines between Fuchs uveitis syndrome (FUS) eyes and the senile cataract eyes. The association between inflammatory cytokine levels and cataract severity...

    Authors: Hui Wang and Yong Tao
    Citation: BMC Ophthalmology 2021 21:108
    Content type: Research article Published on:

  34. Un-operated cataract is the leading cause of vision loss worldwide, responsible for 33% of visual impairment, and half of global blindness. The study aimed to build a fast evaluation method utilizing Andersen’...

    Authors: Senlin Lin, Yingyan Ma, Zhiyuan Hou, Nathan Congdon, Lina Lu and Haidong Zou
    Citation: BMC Ophthalmology 2021 21:107
    Content type: Research article Published on:

  35. The purpose of this study is to report the safety and efficacy of pars plana glaucoma drainage devices with pars plana vitrectomy using one of the vitrectomy sclerotomy sites for tube placement in patients wit...

    Authors: Enchi Kristina Chang, Sanchay Gupta, Marika Chachanidze, John B. Miller, Ta Chen Chang and David A. Solá-Del Valle
    Citation: BMC Ophthalmology 2021 21:106
    Content type: Research article Published on:

  36. Cogan’s anterior internuclear ophthalmoplegia (INO) is characterized by INO with inability to converge and commonly thought to be due to rostral midbrain lesion. A lesion outside midbrain that causes unilatera...

    Authors: Yong Zheng Wai, Qi Xiong Ng, Tsu Hong Lim and Lik Thai Lim
    Citation: BMC Ophthalmology 2021 21:105
    Content type: Case report Published on:

  37. Hyperoxia-mediated inhibition of vascular endothelial growth factor (VEGF) in the retina is the main cause of impeded angiogenesis during phase I retinopathy of prematurity (ROP). Human retinal angiogenesis in...

    Authors: Lan Jian, Yang Mei, Chen Xing and Yuan Rongdi
    Citation: BMC Ophthalmology 2021 21:104
    Content type: Research article Published on:

  38. The dacryoendoscope is the only instrument that can observe the luminal side of the lacrimal passage with minimal invasiveness. It was developed to treat lacrimal passage obstructions by inserting a bicanalicu...

    Authors: Tomoyuki Kamao, Xiaodong Zheng and Atsushi Shiraishi
    Citation: BMC Ophthalmology 2021 21:103
    Content type: Research article Published on:

  40. The natural course of a vortex vein varix, though not well understood, has been known to remain stable. However, here we report a novel case of a vortex vein varix that resolved after an extended period of mon...

    Authors: Sara L Weidmayer and Hakan Demirci
    Citation: BMC Ophthalmology 2021 21:101
    Content type: Case report Published on:

  41. Numerous studies have confirmed the association of ambient temperature and air pollution with a higher risk of morbidities, yet few have addressed their effect on the ocular system. The purpose of this study w...

    Authors: S. Khalaila, T. Coreanu, A. Vodonos, I. Kloog, A. Shtein, L. E. Colwell, V. Novack and E. Tsumi
    Citation: BMC Ophthalmology 2021 21:100
    Content type: Research article Published on:

  42. The use of a tissue patch graft is common practice with a glaucoma drainage device (GDD). Patch grafts can be visible in the palpebral fissure and may be cosmetically displeasing for some patients. The aim of ...

    Authors: Doaa S. Milibari, Dalal Fatani, Abeer Ahmad, Ohoud Owaidhah, Saleh A. AlObeidan, Faisal A. Almobarak and Rizwan Malik
    Citation: BMC Ophthalmology 2021 21:99
    Content type: Research article Published on:

  43. Photodynamic therapy (PDT) is known to occlude choroidal neovascularisation selectively, and there have been several reports on its adverse effects on the normal choroid and retinal pigment epithelium, resulti...

    Authors: Min Ho Kim, Yoo-Ri Chung and Ji Hun Song
    Citation: BMC Ophthalmology 2021 21:98
    Content type: Research article Published on:

  44. The prevalence of age-related macular degeneration (AMD) varies from 6.8 to 18.3% for all forms of AMD and from 0.6 to 2.6% for late AMD according to race, suggesting the existence of genetic differences among...

    Authors: Hyun-Tae Shin, Byung Woo Yoon and Je Hyun Seo
    Citation: BMC Ophthalmology 2021 21:97
    Content type: Research article Published on:

  45. Globally, visual impairment affects about 285 million (4.25%) people, of those, 266.4 million were adults aged 18 years and above. Ethiopia is one of developing countries estimated to have high prevalence of v...

    Authors: Haimanot Abebe, Fasil Wagnew, Haymanot Zeleke, Bitew Tefera, Shegaw Tesfa and Tamene Fetene
    Citation: BMC Ophthalmology 2021 21:96
    Content type: Research article Published on:

  46. To analyze whether corneal refractive surgery (CRS) is associated with the distribution of different accommodative dysfunctions (ADs) and binocular dysfunctions (BDs) in civilian pilots. A further aim was to a...

    Authors: Ye Wu, Zhen Zhang, Meng Liao, Qi Li, Xue Lin Tang and Longqian Liu
    Citation: BMC Ophthalmology 2021 21:95
    Content type: Research article Published on:

  47. Polypoidal choroidal vasculopathy (PCV) is a type of age-related macular degeneration that can cause permanent vision loss. The purpose of this paper was to report the one-year outcomes of fixed-dosing afliber...

    Authors: Hun Gu Choo, Jin Hae Lee, Hyun Sub Oh, Soon Hyun Kim, Yong Sung You and Oh Woong Kwon
    Citation: BMC Ophthalmology 2021 21:94
    Content type: Research article Published on:

  50. Myopia is hypothesized to be influenced by environmental light conditions. For example, it has been shown that colour and temporal frequency of flickering light affect emmetropisation in animals. Considering t...

    Authors: Liyue Zhang, Dongyu Guo, Chen Xie, Yingying Wen, Xuhong Zhang, Le Jin, Jianping Tong and Ye Shen
    Citation: BMC Ophthalmology 2021 21:88
    Content type: Research article Published on:
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