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  1. The aim of this study was to evaluate the effects of systemic parameters, laboratory findings, oral parameters, and other ocular surface parameters on ocular surface epithelial damage in patients with primary ...

    Authors: Ji Eun Kim, Na Rae Kim, Hee Seung Chin, Kyoung Yul Seo, Tae-im Kim and Ji Won Jung

    Citation: BMC Ophthalmology 2021 21:114

    Content type: Research article

    Published on:

  2. To compare ocular and corneal inherent aberrations in the naked eyes of randomly selected children fitted with MiSight contact lenses (CL) for myopia control, versus children corrected with single-vision spect...

    Authors: Daniela Lopes-Ferreira, Alicia Ruiz-Pomeda, Belén Peréz-Sanchéz, António Queirós and César Villa-Collar

    Citation: BMC Ophthalmology 2021 21:112

    Content type: Research article

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  4. Cataract surgeries can improve mental health outcomes. However, previous studies have not investigated whether the time interval between cataract surgeries for 2 eyes affects mental health outcomes.

    Authors: Chiun-Ho Hou, Ken-Jen Chen, Jiahn-Shing Lee, Ken-Kuo Lin and Christy Pu

    Citation: BMC Ophthalmology 2021 21:110

    Content type: Research article

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  5. Treatment of recurrent retinal detachment (re-RD) following vitrectomy (post-gas/air tamponade and post-silicone oil removal) is challenging. Previously reported treatment is commonly revision pars plana vitre...

    Authors: Jun-Xing Bai, Xiao-Jian Zhang, An-Li Duan and Xiao-Yan Peng

    Citation: BMC Ophthalmology 2021 21:109

    Content type: Research article

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  6. This study aims to compare the levels of intraocular cytokines between Fuchs uveitis syndrome (FUS) eyes and the senile cataract eyes. The association between inflammatory cytokine levels and cataract severity...

    Authors: Hui Wang and Yong Tao

    Citation: BMC Ophthalmology 2021 21:108

    Content type: Research article

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  7. Un-operated cataract is the leading cause of vision loss worldwide, responsible for 33% of visual impairment, and half of global blindness. The study aimed to build a fast evaluation method utilizing Andersen’...

    Authors: Senlin Lin, Yingyan Ma, Zhiyuan Hou, Nathan Congdon, Lina Lu and Haidong Zou

    Citation: BMC Ophthalmology 2021 21:107

    Content type: Research article

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  8. The purpose of this study is to report the safety and efficacy of pars plana glaucoma drainage devices with pars plana vitrectomy using one of the vitrectomy sclerotomy sites for tube placement in patients wit...

    Authors: Enchi Kristina Chang, Sanchay Gupta, Marika Chachanidze, John B. Miller, Ta Chen Chang and David A. Solá-Del Valle

    Citation: BMC Ophthalmology 2021 21:106

    Content type: Research article

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  9. Cogan’s anterior internuclear ophthalmoplegia (INO) is characterized by INO with inability to converge and commonly thought to be due to rostral midbrain lesion. A lesion outside midbrain that causes unilatera...

    Authors: Yong Zheng Wai, Qi Xiong Ng, Tsu Hong Lim and Lik Thai Lim

    Citation: BMC Ophthalmology 2021 21:105

    Content type: Case report

    Published on:

  10. Hyperoxia-mediated inhibition of vascular endothelial growth factor (VEGF) in the retina is the main cause of impeded angiogenesis during phase I retinopathy of prematurity (ROP). Human retinal angiogenesis in...

    Authors: Lan Jian, Yang Mei, Chen Xing and Yuan Rongdi

    Citation: BMC Ophthalmology 2021 21:104

    Content type: Research article

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  11. The dacryoendoscope is the only instrument that can observe the luminal side of the lacrimal passage with minimal invasiveness. It was developed to treat lacrimal passage obstructions by inserting a bicanalicu...

    Authors: Tomoyuki Kamao, Xiaodong Zheng and Atsushi Shiraishi

    Citation: BMC Ophthalmology 2021 21:103

    Content type: Research article

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  13. The natural course of a vortex vein varix, though not well understood, has been known to remain stable. However, here we report a novel case of a vortex vein varix that resolved after an extended period of mon...

    Authors: Sara L Weidmayer and Hakan Demirci

    Citation: BMC Ophthalmology 2021 21:101

    Content type: Case report

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  14. Numerous studies have confirmed the association of ambient temperature and air pollution with a higher risk of morbidities, yet few have addressed their effect on the ocular system. The purpose of this study w...

    Authors: S. Khalaila, T. Coreanu, A. Vodonos, I. Kloog, A. Shtein, L. E. Colwell, V. Novack and E. Tsumi

    Citation: BMC Ophthalmology 2021 21:100

    Content type: Research article

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  15. The use of a tissue patch graft is common practice with a glaucoma drainage device (GDD). Patch grafts can be visible in the palpebral fissure and may be cosmetically displeasing for some patients. The aim of ...

    Authors: Doaa S. Milibari, Dalal Fatani, Abeer Ahmad, Ohoud Owaidhah, Saleh A. AlObeidan, Faisal A. Almobarak and Rizwan Malik

    Citation: BMC Ophthalmology 2021 21:99

    Content type: Research article

    Published on:

  16. Photodynamic therapy (PDT) is known to occlude choroidal neovascularisation selectively, and there have been several reports on its adverse effects on the normal choroid and retinal pigment epithelium, resulti...

    Authors: Min Ho Kim, Yoo-Ri Chung and Ji Hun Song

    Citation: BMC Ophthalmology 2021 21:98

    Content type: Research article

    Published on:

  17. The prevalence of age-related macular degeneration (AMD) varies from 6.8 to 18.3% for all forms of AMD and from 0.6 to 2.6% for late AMD according to race, suggesting the existence of genetic differences among...

    Authors: Hyun-Tae Shin, Byung Woo Yoon and Je Hyun Seo

    Citation: BMC Ophthalmology 2021 21:97

    Content type: Research article

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  18. Globally, visual impairment affects about 285 million (4.25%) people, of those, 266.4 million were adults aged 18 years and above. Ethiopia is one of developing countries estimated to have high prevalence of v...

    Authors: Haimanot Abebe, Fasil Wagnew, Haymanot Zeleke, Bitew Tefera, Shegaw Tesfa and Tamene Fetene

    Citation: BMC Ophthalmology 2021 21:96

    Content type: Research article

    Published on:

  19. To analyze whether corneal refractive surgery (CRS) is associated with the distribution of different accommodative dysfunctions (ADs) and binocular dysfunctions (BDs) in civilian pilots. A further aim was to a...

    Authors: Ye Wu, Zhen Zhang, Meng Liao, Qi Li, Xue Lin Tang and Longqian Liu

    Citation: BMC Ophthalmology 2021 21:95

    Content type: Research article

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  20. Polypoidal choroidal vasculopathy (PCV) is a type of age-related macular degeneration that can cause permanent vision loss. The purpose of this paper was to report the one-year outcomes of fixed-dosing afliber...

    Authors: Hun Gu Choo, Jin Hae Lee, Hyun Sub Oh, Soon Hyun Kim, Yong Sung You and Oh Woong Kwon

    Citation: BMC Ophthalmology 2021 21:94

    Content type: Research article

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  23. Eye examination and vision assessment are vital for the detection of conditions that result in blindness. Childhood blindness seriously impacts the development, education, and future employment opportunities o...

    Authors: Tolosa Tufa Regassa, Kumale Tolesa Daba, Ido Didi Fabian and Aemero Abateneh Mengasha

    Citation: BMC Ophthalmology 2021 21:91

    Content type: Research article

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  24. Anti–vascular endothelial growth factor (anti-VEGF) agents have become the standard of care in neovascular age-related macular degeneration (nAMD). Despite generally excellent response rates to anti-VEGF thera...

    Authors: Sam Razavi, Laurent Kodjikian, Audrey Giocanti-Aurégan, Ingrid Dufour and Eric Souied

    Citation: BMC Ophthalmology 2021 21:90

    Content type: Research article

    Published on:

  25. For clinical practice it is important to evaluate and compare anxiety, depression and quality of life of glaucoma patients with painless one-eye blindness and a normal fellow eye to unaffected age-matched indi...

    Authors: Gábor Holló, Nikolett Gabriella Sándor, Péter Kóthy and Anna Géczy

    Citation: BMC Ophthalmology 2021 21:89

    Content type: Research

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  26. Myopia is hypothesized to be influenced by environmental light conditions. For example, it has been shown that colour and temporal frequency of flickering light affect emmetropisation in animals. Considering t...

    Authors: Liyue Zhang, Dongyu Guo, Chen Xie, Yingying Wen, Xuhong Zhang, Le Jin, Jianping Tong and Ye Shen

    Citation: BMC Ophthalmology 2021 21:88

    Content type: Research article

    Published on:

  29. To acquire desirable outcomes of penetrating keratoplasty (PKP), various factors affecting graft survival, visual function, and subjective symptom should be considered. As ocular surface and meibomian gland fu...

    Authors: Kang Yoon Kim, Byunghoon Chung, Eung Kweon Kim, Kyoung Yul Seo, Ikhyun Jun and Tae-im Kim

    Citation: BMC Ophthalmology 2021 21:85

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Ophthalmology 2021 21:118

  31. To investigate the efficacy and predictability of Muller’s muscle-conjunctival resection (MMCR) with different lengths of tarsectomy for the treatment of unilateral mild-to-moderate blepharoptosis.

    Authors: So-Hung Yeh, Shu-Lang Liao and Yi-Hsuan Wei

    Citation: BMC Ophthalmology 2021 21:83

    Content type: Research article

    Published on:

  32. Quantitative assessment of vascular density (VD) of retinal and choriocapillaris (CC) in various stages of diabetic retinopathy (DR) using spectral domain optical coherence tomography angiography (SD OCTA).

    Authors: Fariba Ghassemi, Kaveh Fadakar, Sahar Berijani, Ameneh Babeli, Alireza Gholizadeh and Siamak Sabour

    Citation: BMC Ophthalmology 2021 21:82

    Content type: Research article

    Published on:

  33. Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to condu...

    Authors: Xujia Liu, Zehua Jiang, Guihua Zhang, Tsz Kin Ng and Zhenggen Wu

    Citation: BMC Ophthalmology 2021 21:81

    Content type: Research article

    Published on:

  34. We discuss the safety, since their introduction, of phakic intraocular lenses (pIOLs) to correct refractive errors in healthy eyes. We investigated the reasons for pIOL explantation and the associated perioper...

    Authors: Timur M. Yildirim, Ramin Khoramnia, Hyeck-Soo Son, Christian S. Mayer, Grzegorz Łabuz, Donald J. Munro and Gerd U. Auffarth

    Citation: BMC Ophthalmology 2021 21:80

    Content type: Research article

    Published on:

  35. Globally, at least 1 billion people have a vision impairment that could have been easily prevented or easily treated. Cataract is the leading preventable and most treatable causes of blindness and bilateral lo...

    Authors: Anteneh Fikrie, Yonatan G. Mariam, Elias Amaje and Henok Bekele

    Citation: BMC Ophthalmology 2021 21:79

    Content type: Research article

    Published on:

  37. To investigate the effect of nicergoline on the rate of complete corneal ulcer reepithelialization (CCUR) in diabetic rats with diabetic keratopathy.

    Authors: Amanda Lemos Barros Martins Portela, Rafael Neves Moreno, Maria Helena Madruga Lima Ribeiro, Fernanda Miguel de Andrade, Yale Viana Alves, Mônica Alves and Rodrigo Pessoa Cavalcanti Lira

    Citation: BMC Ophthalmology 2021 21:77

    Content type: Research article

    Published on:

  38. Increased use of the transorbital approach (TOA) warrants greater understanding of the risk of increased intraocular pressure (IOP) and intraorbital pressure (IORP) due to orbital compression. We aimed to inve...

    Authors: Woohyun Kim, Ju Hyung Moon, Eui Hyun Kim, Chang-Ki Hong, Jisang Han and Je Beom Hong

    Citation: BMC Ophthalmology 2021 21:76

    Content type: Research article

    Published on:

  40. Glaucoma drainage implants have been used with increasing frequency for the management of glaucoma. Patients who are candidates for glaucoma drainage devices often have more severe disease and are at risk of v...

    Authors: Monica Kenney Ertel, Nathaniel Ryan Gelinas, Taylor John Slingsby, Leonard Keith Seibold, Malik Yaser Kahook and Jeffrey Raymond SooHoo

    Citation: BMC Ophthalmology 2021 21:74

    Content type: Case report

    Published on:

  43. The purpose of the study is to investigate the changes of macular perfusion by OCT-angiography (OCT-A) after uncomplicated phacoemulsification.

    Authors: Ana Križanović, Mirjana Bjeloš, Mladen Bušić, Biljana Kuzmanović Elabjer, Benedict Rak and Nenad Vukojević

    Citation: BMC Ophthalmology 2021 21:71

    Content type: Research article

    Published on:

  44. Using telemedicine for diabetic retinal screening is becoming popular especially amongst at-risk urban communities with poor access to care. The goal of the diabetic telemedicine project at Temple University H...

    Authors: James E. Benjamin, Justin Sun, Devin Cohen, Joseph Matz, Angela Barbera, Jeffrey Henderer, Lorrie Cheng, Julia Grachevskaya, Rajnikant Shah and Yi Zhang

    Citation: BMC Ophthalmology 2021 21:70

    Content type: Research article

    Published on:

  45. Open globe injury (OGI) is one of the most devastating form of ocular trauma. The aim of the study is to identify the epidemiology and predict visual outcomes in traumatic open globe injuries using ocular trau...

    Authors: Saurav M. Shrestha, Casey L. Anthony, Grant A. Justin, Madhu Thapa, Jyoti B. Shrestha, Anadi Khatri, Annette K Hoskin and Rupesh Agrawal

    Citation: BMC Ophthalmology 2021 21:69

    Content type: Research article

    Published on:

  46. To analyze multiple imaging modalities in patients with Bietti crystalline dystrophy (BCD) and to investigate which factors from these modalities are associated with best corrected visual acuity (BCVA).

    Authors: Chu-Yen Huang, Eugene Yu-Chuan Kang, Lung-Kun Yeh, An-Lun Wu, Pei-Kang Liu, I-Wen Huang, Joseph Ryu, Laura Liu, Wei-Chi Wu, Chi-Chun Lai, Kuan-Jen Chen and Nan-Kai Wang

    Citation: BMC Ophthalmology 2021 21:68

    Content type: Research article

    Published on:

  47. Aniso-astigmatism may hinder normal visual development in preschool children. Knowing its prevalence, biometric parameters and risk factors is fundamental to children eye care. The purpose of this study was to...

    Authors: Haohai Tong, Qingfeng Hao, Zijin Wang, Yue Wang, Rui Li, Xiaoyan Zhao, Qigang Sun, Xiaohan Zhang, Xuejuan Chen, Hui Zhu, Dan Huang and Hu Liu

    Citation: BMC Ophthalmology 2021 21:67

    Content type: Research article

    Published on:

  48. Solitary extramedullary plasmacytoma (SEP) is a localised proliferation of monoclonal plasma cells involving soft tissue with no or minimal bone marrow involvement and no other systemic evidence of multiple my...

    Authors: Tom Ayton, Svetlana Cherepanoff, David Gottlieb, William A. Sewell, Sandy Smith and Claire Hooper

    Citation: BMC Ophthalmology 2021 21:66

    Content type: Case report

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  49. Hemolytic Uremic Syndrome (HUS) is a rare disorder characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure, considered within the group of thrombocytic microa...

    Authors: David Pérez González, Matias Iglicki, Shuli Svetitsky, Yaeli Bar-On, Zohar Habot-Wilner and Dinah Zur

    Citation: BMC Ophthalmology 2021 21:65

    Content type: Case report

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  50. Thygeson’s superficial punctate keratitis (TSPK) is reportedly a rare disease with an insidious onset, numerous remissions and exacerbations, and a long duration. The corneal lesions are elevated, whitish–grey...

    Authors: Xiao-Jiao Tang, Qing Liu, Lian-Hong Pi, Xin-Ke Chen and Lin Chen

    Citation: BMC Ophthalmology 2021 21:64

    Content type: Case report

    Published on:

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