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  1. Peters plus syndrome (PPS) is a combination of congenital Peters anomaly and systemic abnormalities. It is inherited most commonly in an autosomal recessive pattern with homozygous B3GLCT mutations. Ocular findin...

    Authors: Ye Elaine Wang, Dhariana Acon Ramirez, Ta Chen Chang and Audina Berrocal

    Citation: BMC Ophthalmology 2020 20:118

    Content type: Case report

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  2. A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surge...

    Authors: Henry Bair, Chun-Ju Lin, Chun-Ting Lai, Ning-Yi Hsia and Yi-Yu Tsai

    Citation: BMC Ophthalmology 2020 20:117

    Content type: Case report

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  3. To evaluate the feasibility of a surgical technique using a sub-perfluoro-n-octane (PFO) injection of ocular viscoelastic device (OVD) to stabilize inverted internal limiting membrane (ILM) flap for the treatm...

    Authors: Chi-Chun Lai, An-Lun Wu, Hung-Da Chou, Wee Min Teh, Kuan-Jen Chen, Yen-Po Chen, Laura Liu, Yih-Shiou Hwang and Wei-Chi Wu

    Citation: BMC Ophthalmology 2020 20:116

    Content type: Research article

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  4. This study aimed to evaluate the visual and morphological outcomes of intravitreal anti-VEGF therapy and the recurrence for idiopathic choroidal neovascularization (ICNV).

    Authors: Qianru Wu, Xiaoyong Chen, Kang Feng, Yuling Liu, Chun Zhang and Lin Zhao

    Citation: BMC Ophthalmology 2020 20:115

    Content type: Research article

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  5. Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagno...

    Authors: Takumasa Tsuji, Yuta Hirose, Kohei Fujimori, Takuya Hirose, Asuka Oyama, Yusuke Saikawa, Tatsuya Mimura, Kenshiro Shiraishi, Takenori Kobayashi, Atsushi Mizota and Jun’ichi Kotoku

    Citation: BMC Ophthalmology 2020 20:114

    Content type: Research article

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  6. Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this c...

    Authors: Mingyue Luo, Zhe Chen, Yaping Luo, Lin Zhao, Rongping Dai and Yong Zhong

    Citation: BMC Ophthalmology 2020 20:113

    Content type: Case report

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  7. In this case presentation, we present a young vegan patient who developed a CRVO secondary to severe iron-deficiency anaemia (IDA) attributable to menstrual losses and limited iron intake. CRVO is a rare compl...

    Authors: Verlyn Yang, Liam Daniel Turner and Fraser Imrie

    Citation: BMC Ophthalmology 2020 20:112

    Content type: Case report

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  8. The aim of this study was to evaluate the efficacy and safety of M22 Optimal Pulsed Technology (OPT) applied in patients with age-related cataract and Meibomian gland dysfunction (MGD) in perioperative period.

    Authors: Jinling Ge, Na Liu, Xiaoming Wang, Ying Du, Chaoqing Wang, Zhaorui Li, Jing Li and Lihua Wang

    Citation: BMC Ophthalmology 2020 20:111

    Content type: Research article

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  9. To evaluate the differences between the predicted and achieved lenticule thickness (ΔLT) after small incision lenticule extraction (SMILE) surgery and investigate relationships between ΔLT and predicted lentic...

    Authors: Fang Wu, Houfa Yin, Xinyi Chen and Yabo Yang

    Citation: BMC Ophthalmology 2020 20:110

    Content type: Research article

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  10. Macular hole (MH) is a retinal break in the fovea involving partial or complete dehiscence of the neural retinal layers affecting the visual quality by decreasing visual acuity (VA) and visual deformation. We ...

    Authors: Minami Chino, Yuji Yoshikawa, Junji Kanno, Takamitsu Nagashima, Yu Sakaki, Takeshi Katsumoto, Masayuki Shibuya, Takuhei Shoji, Jun Makita and Kei Shinoda

    Citation: BMC Ophthalmology 2020 20:108

    Content type: Case report

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  11. To measure the microcirculation change of macula and optic nerve head before and after femtosecond laser assisted laser in situ keratomileusis.

    Authors: Yan Zhang, Jianqing Lan, Dan Cao, Cheng Yang, Dawei Yang, Wenjuan Xie and Jin Zeng

    Citation: BMC Ophthalmology 2020 20:107

    Content type: Research article

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  12. Blood-retinal barrier cells are known to exhibit a massive phenotypic change during experimental autoimmune uveitis (EAU) development. In an attempt to investigate the mechanisms of blood-retinal barrier (BRB)...

    Authors: Deborah A. Lipski, Vincent Foucart, Rémi Dewispelaere, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns and François Willermain

    Citation: BMC Ophthalmology 2020 20:106

    Content type: Research article

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  13. To study the morphologic and biochemical changes in the retina and sclera induced by form deprivation high myopia (FDHM) in guinea pigs and explore the possible mechanisms of FDHM formation.

    Authors: Yingxin Zi, Yu Deng, Jingru Zhao, Meiqi Ji, Yali Qin, Tingting Deng and Ming Jin

    Citation: BMC Ophthalmology 2020 20:105

    Content type: Research article

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  14. The purpose was to describe the Nordic treatment practices and to reach a Nordic consensus for the treatment of sebaceous eyelid carcinoma.

    Authors: Tiina Leivo, Johanna Sarmela, Maria Enckell-Aaltonen, Eva Dafgård Kopp, Caroline Schmitt, Peter B. Toft, Haraldur Sigurdsson and Marita Uusitalo

    Citation: BMC Ophthalmology 2020 20:103

    Content type: Research article

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  15. In diabetic eyes, various choroidal abnormalities are noted in addition to changes in the retinal circulation, and the risk of increased aqueous flare and retinal thickening after cataract surgery is higher in...

    Authors: Yasuko Ikegami, Miyuki Takahashi and Kana Amino

    Citation: BMC Ophthalmology 2020 20:102

    Content type: Research article

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  16. Pseudoduplication of the optic disc is a rare clinical condition that is characterized by a circumscribed, disc-like lesion with radiating vessels but only one normal optic nerve. We report a rare case that in...

    Authors: Liuhui Huang, Qi Zhang, Haiying Jin and Peiquan Zhao

    Citation: BMC Ophthalmology 2020 20:101

    Content type: Case report

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  17. The aim of this study was to review the demographic and characteristic distribution data of serious rural pediatric eye injuries in Wenzhou and Changsha, located in Zhejiang Province in East China and Hunan Pr...

    Authors: Chunyan Li, Yaoyao Lin, Haishao Xiao, Huan Lin, Yanyan Chen and Minhui Dai

    Citation: BMC Ophthalmology 2020 20:100

    Content type: Research article

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  18. To evaluate the prevalence of blepharoptosis among Korean adults and the characteristics of blepharoptosis patients, and to determine an appropriate age threshold for recommending blepharoptosis evaluation.

    Authors: Ji-Sun Paik, Kyungdo Han, Suk-Woo Yang, Yongkyu Park, Kyungsun Na, Wonkyung Cho, Su-Kyung Jung and Sungeun Kim

    Citation: BMC Ophthalmology 2020 20:99

    Content type: Research article

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  19. Systemic lupus erythematosus (SLE) can directly affect various part of the ocular system, but there was no comprehensive analysis of ophthalmic disorders of patients with SLE using population-based data. The a...

    Authors: Chun-Shuo Hsu, Chia-Wen Hsu, Ming-Chi Lu and Malcolm Koo

    Citation: BMC Ophthalmology 2020 20:96

    Content type: Research article

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  20. This study aimed to investigate the pre- and post-surgery reading ability in patients with idiopathic epiretinal membrane (ERM) to evaluate whether measurement of reading performance is a helpful test in addit...

    Authors: Hiroki Mieno, Kentaro Kojima, Kazuhito Yoneda, Fumie Kinoshita, Rentaro Mizuno, Shinnosuke Nakaji and Chie Sotozono

    Citation: BMC Ophthalmology 2020 20:95

    Content type: Research article

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  21. Hematologic malignancies occasionally cause serous retinal detachment (SRD); however, its pathogenesis remains unclear. Here we present the imaging characteristics of metastatic choroidal lymphoma masquerading...

    Authors: Kanae Fukutsu, Kenichi Namba, Daiju Iwata, Kazuomi Mizuuchi, Satoru Kase, Kayo Suzuki, Hiroshi Shimizu, Yukiko Shibata, Fumihiko Yamawaki, Masahiro Onozawa and Susumu Ishida

    Citation: BMC Ophthalmology 2020 20:94

    Content type: Case report

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  22. Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) tech...

    Authors: Wen-ping Song, Si Zheng, Hong-juan Yao, Xiao-fei Zhou, Rui Li, Cheng-yue Zhang, Jun-yang Zhao, Lie-wei Wang, Rong-guang Shao and Liang Li

    Citation: BMC Ophthalmology 2020 20:92

    Content type: Research article

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  23. To compare vision-related quality of life (VRQOL) between acute and chronic Central serous chorioretinopathy (CSC) and correlate this with Cohen’s Perceived Stress Scale (PSS) questionnaire.

    Authors: Meenakshi Kumar, Elon H. C. van Dijk, Rajiv Raman, Pooja Mehta, Camiel J. F. Boon, Abhilash Goud, Seelam Bharani and Jay Chhablani

    Citation: BMC Ophthalmology 2020 20:90

    Content type: Research article

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  24. We aimed to demonstrate the contribution of anti-inflammatory and anti-virulence effects of azithromycin (AZM) in ocular surface infection treatment.

    Authors: Kana Ikemoto, Shinya Kobayashi, Yu Haranosono, Seiko Kozai, Tomoyuki Wada, Hideki Tokushige and Akio Kawamura

    Citation: BMC Ophthalmology 2020 20:89

    Content type: Research article

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  25. To compare the anterior biometrics in eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chro...

    Authors: Xiaoli Xing, Liangyu Huang, Fang Tian, Yan Zhang, Yingjuan Lv, Wei Liu and Aihua Liu

    Citation: BMC Ophthalmology 2020 20:87

    Content type: Research article

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  26. Postoperative nausea and vomiting (PONV) are common side-effects following strabismus surgery. The present study aimed to compare the effects of different doses of dexmedetomidine (DEX) on PONV incidence in pe...

    Authors: Shuangshuang Li, Tingjie Liu, Junming Xia, Jie Jia and Wenxian Li

    Citation: BMC Ophthalmology 2020 20:86

    Content type: Research article

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  27. The aim of this study was to explore the differences in terms of tear film and meibomian glands (MGs) between young Asian soft contact lens (CL) wearers and non-wearers.

    Authors: Tianpu Gu, Lu Zhao, Zhuzhu Liu, Shaozhen Zhao, Hong Nian and Ruihua Wei

    Citation: BMC Ophthalmology 2020 20:84

    Content type: Research article

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  28. The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting ...

    Authors: Tianrui He, Yi Zhu and Jibo Zhou

    Citation: BMC Ophthalmology 2020 20:82

    Content type: Research article

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  29. Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates...

    Authors: Marc Labetoulle, Anders Behndig, Marie-José Tassignon, Rudy Nuijts, Rita Mencucci, José Luis Güell, Uwe Pleyer, Jacek Szaflik, Paul Rosen, Alain Bérard, Frédéric Chiambaretta and Béatrice Cochener-Lamard

    Citation: BMC Ophthalmology 2020 20:81

    Content type: Research article

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  30. Young adults with type 2 diabetes (aged 18–39 years) are at risk of early onset and rapid progression of diabetic retinopathy, the leading cause of blindness and vision loss in working age adults. Early detect...

    Authors: Amelia J. Lake, Jessica L. Hateley-Browne, Gwyneth Rees and Jane Speight

    Citation: BMC Ophthalmology 2020 20:80

    Content type: Research article

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  31. Posterior capsule opacification (PCO) after cataract surgery is influenced by intraocular lens (IOL) design and material. The following is an ex vivo comparison of PCO between the Clareon vs. the AcrySof IOL i...

    Authors: Anna Hillenmayer, Christian M. Wertheimer, Stefan Kassumeh, Annabel von Studnitz, Nikolaus Luft, Andreas Ohlmann, Siegfried Priglinger and Wolfgang J. Mayer

    Citation: BMC Ophthalmology 2020 20:77

    Content type: Research article

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  32. The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in S...

    Authors: Daniel Beck, Martin Galea, Cheng Yi Loo, Conrad Schmoll, Frederick R. Burgess, Donald Montgomery and Andrew J. Tatham

    Citation: BMC Ophthalmology 2020 20:76

    Content type: Research article

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  33. Presence of corneal cystine crystals is the main ocular manifestation of cystinosis, although controversial findings concerning the corneal layer with the highest density have been reported. The aim of this st...

    Authors: Anita Csorba, Erika Maka, Otto Alexander Maneschg, Attila Szabó, Nóra Szentmáry, Mária Csidey, Miklós Resch, László Imre, Krisztina Knézy and Zoltán Zsolt Nagy

    Citation: BMC Ophthalmology 2020 20:73

    Content type: Research article

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  34. Primary objective of this review was to measure compliance with spectacle use in children with refractive errors. Secondary objective was to understand the reasons for non-compliance.

    Authors: Nonita Dhirar, Sankalp Dudeja, Mona Duggal, Parul Chawla Gupta, Nishant Jaiswal, Meenu Singh and Jagat Ram

    Citation: BMC Ophthalmology 2020 20:71

    Content type: Research article

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  35. Usher syndrome (USH) is the most prevalent cause of the human genetic deafness and blindness. USH type II (USH2) is the most common form of USH, and USH2A is the major pathogenic gene for USH2. For expanding the ...

    Authors: Chenhao He, Xinyu Liu, Zilin Zhong and Jianjun Chen

    Citation: BMC Ophthalmology 2020 20:70

    Content type: Research article

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  36. To evaluate the safety and efficacy of a treat-and-extend protocol of aflibercept for cystoid macular oedema (CMO) secondary to central retinal vein occlusion (CRVO).

    Authors: Roderick O’Day, Noha Ali, Lyndell L. Lim, Sukhpal Sandhu, Thuy Chau and Sanjeewa Wickremasinghe

    Citation: BMC Ophthalmology 2020 20:69

    Content type: Research article

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  37. Congenital mydriasis and retinal arteriolar tortuosity are associated with the life-threatening multisystemic smooth muscle dysfunction syndrome (MSMDS) due to mutations in the gene, ACTA2, which encodes alpha-sm...

    Authors: Aisling B. Mc Glacken-Byrne, David Prentice, Danial Roshandel, Michael R. Brown, Philip Tuch, Kyle S.-Y. Yau, Padma Sivadorai, Mark R. Davis, Nigel G. Laing and Fred K. Chen

    Citation: BMC Ophthalmology 2020 20:68

    Content type: Case report

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  38. It is well known that the biomechanical properties change after LASIK refractive surgery. One reason is the impact of flap creation on the residual stroma. The results have revealed that the change is closely ...

    Authors: Lihua Fang, Yan Wang, Ruizhi Yang, Sijing Deng, Jiahao Deng and Linsun Wan

    Citation: BMC Ophthalmology 2020 20:67

    Content type: Research article

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  39. Glaucoma drainage device (GDD) implantation in the anterior chamber are associated with corneal complications. We describe a novel technique to implant GDD tubes in the posterior chamber of pseudophakic eyes.

    Authors: Javier Moreno-Montañés, Concepción Guirao-Navarro and Francisco Argüeso

    Citation: BMC Ophthalmology 2020 20:66

    Content type: Technical advance

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  40. Alveolar soft part sarcoma (ASPS) is a clinically and morphologically distinct malignant soft tissue tumour. It occurs mostly in the lower extremities in adults. The purpose of our study was to describe the re...

    Authors: Yujiao Wang, Baixue Du, Mei Yang and Weimin He

    Citation: BMC Ophthalmology 2020 20:60

    Content type: Case report

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  41. Previously, we showed that serum malondialdehyde (MDA) was significantly higher in patients with neovascular age-related macular degeneration (nAMD) than in those without AMD. The Diacron reactive oxygen metab...

    Authors: Toshiyuki Matsuura, Hiroki Kaneko, Kei Takayama, Rei Shibata, Keiko Kataoka, Seina Ito, Taichi Tsunekawa, Hideyuki Shimizu, Ayana Suzumura, Rina Namba, Yasuki Ito, Toyoaki Murohara and Hiroko Terasaki

    Citation: BMC Ophthalmology 2020 20:56

    Content type: Research article

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