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  1. Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic un...

    Authors: Weiming Yan, Pan Long, Dongyu Wei, Weihua Yan, Xiangrong Zheng, Guocang Chen, Jiancong Wang, Zuoming Zhang, Tao Chen and Meizhu Chen

    Citation: BMC Ophthalmology 2020 20:55

    Content type: Research article

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  2. Knowing the pattern and presentation of the diseases is critical for management strategies. To inform eye-care policy we quantified the pattern of vitreo-retinal (VR) diseases presenting at the national referr...

    Authors: Bhim B. Rai, Michael G. Morley, Paul S. Bernstein and Ted Maddess

    Citation: BMC Ophthalmology 2020 20:51

    Content type: Research article

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  3. Corneal densitometry, which is also known as corneal backscattering, is a surrogate measure of corneal clarity. The purpose of the study was to investigate the changes in corneal densitometry (CD) after implan...

    Authors: Xun Chen, Yang Shen, Haipeng Xu, Xiaoying Wang and Xingtao Zhou

    Citation: BMC Ophthalmology 2020 20:50

    Content type: Research article

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  4. Diagnosis and follow-up of retinal diseases may be improved if the thickness of the various retinal layers, in addition to the total retinal thickness, is taken into account. Here we measured the thickness of ...

    Authors: Qian Wang, Wen Bin Wei, Ya Xing Wang, Yan Ni Yan, Jing Yan Yang, Wen Jia Zhou, Szy Yann Chan, Liang Xu and Jost B. Jonas

    Citation: BMC Ophthalmology 2020 20:49

    Content type: Research article

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  5. Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study ...

    Authors: Cynthia Owsley, Thomas Swain, Rong Liu, Gerald McGwin Jr and Mi Young Kwon

    Citation: BMC Ophthalmology 2020 20:47

    Content type: Research article

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  6. To investigate the prevalence of pterygium and associated factors in Han and Mongolian adults at four survey sites in Inner Mongolia, China.

    Authors: Yuhan Wang, Guangliang Shan, Linyang Gan, Yonggang Qian, Ting Chen, Hailing Wang, Xiaodan Pan, Wenrui Wang, Li Pan, Xia Zhang, Meng Wang, Jin Ma and Yong Zhong

    Citation: BMC Ophthalmology 2020 20:45

    Content type: Research article

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  7. Rapamycin (RAPA) is a potent angiogenic inhibitor and the aim of this study is to identify the inhibitory effect of RAPA on retinal neovascularization (RNV) in experimental oxygen-induced retinopathy (OIR).

    Authors: Feng Jiang, Ying Wang, Shufang Du, Heng Jin and Jindong Han

    Citation: BMC Ophthalmology 2020 20:44

    Content type: Research article

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  8. To investigate the effect of intravitreal conbercept (IVC) injections on the incidence of postoperative vitreous hemorrhage (VH) in eyes undergoing surgery for severe proliferative diabetic retinopathy.

    Authors: Tingting Jiang, Junxiang Gu, Peijun Zhang, Wenwen Chen and Qing Chang

    Citation: BMC Ophthalmology 2020 20:43

    Content type: Research article

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  9. Optical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and disti...

    Authors: Yong Wang, Jinling Zhang, Miaomiao Qin, Jianguo Miao, Wei Chen, Yemeng Huang, Jian Wu, Yu Guan and Huaijin Guan

    Citation: BMC Ophthalmology 2020 20:42

    Content type: Research article

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  10. Previous studies of internal graft-host malappositions have not dealt with the precise ways in which each malapposition affected post-penetrating keratoplasty (post-PK) visual outcomes. In this study, we revie...

    Authors: Yujin Zhao, Hong Zhuang, Jiaxu Hong, Lijia Tian and Jianjiang Xu

    Citation: BMC Ophthalmology 2020 20:41

    Content type: Research article

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  11. To describe factors which influence the age at detection and age at presentation of patients with childhood cataract at a tertiary eye care facility in Southwest Nigeria.

    Authors: Bolutife Ayokunnu Olusanya, Mary Ogbenyi Ugalahi, Adegbola Oluwagbemiga Adeyemo and Aderonke Mojisola Baiyeroju

    Citation: BMC Ophthalmology 2020 20:38

    Content type: Research article

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  12. The purpose of this report is to describe the occurrence of a retinal tear, pre-retinal and vitreous hemorrhages after completing a session of whole-body vibration training. Though our patient is the third doc...

    Authors: John Maggiano, Mei-Chuan Margret Yu, Sanford Chen, Timothy You and Rajiv Rathod

    Citation: BMC Ophthalmology 2020 20:37

    Content type: Case report

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  13. Bruch membrane opening–minimum rim width (BMO–MRW) assessment offers a new diagnostic use in glaucoma patients of the Glaucoma Module Premium Edition (GMPE) available for the Spectralis optical coherence tomog...

    Authors: Maria P. Bambo, Enrique Fuentemilla, Beatriz Cameo, Isabel Fuertes, Blanca Ferrandez, Noemi Güerri, Vicente Polo, Jose M. Larrosa, Luis E. Pablo and Elena Garcia-Martin

    Citation: BMC Ophthalmology 2020 20:35

    Content type: Research article

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  14. Tractional retinal detachment with or without secondary tear is a rare complication reported in less than 0.5% of in eyes treated for retinoblastoma. Pars plana vitrectomy (PPV) in eyes with history of retinob...

    Authors: Christina Stathopoulos, Jessica Sergenti, Marie-Claire Gaillard, Francis L. Munier and Alejandra Daruich

    Citation: BMC Ophthalmology 2020 20:34

    Content type: Case report

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  15. Postoperative intraretinal fluid (IRF) is reportedly associated with visual outcomes after epiretinal membrane (ERM) surgery. However, preoperative IRF is common, and persistent IRF would have different impact...

    Authors: Jae Jung Lee, Yeon Ji Jo, Han Jo Kwon, Seung Min Lee, Sung Who Park, Ik Soo Byon and Ji Eun Lee

    Citation: BMC Ophthalmology 2020 20:33

    Content type: Research article

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  16. Superior oblique weakening is a common method to treat A-pattern strabismus. This study aims to evaluate the surgical results of the bilateral superior oblique posterior tenectomy procedure to treat A-pattern ...

    Authors: Yan Wei, Ling-Yan Dong, Pei-quan Zhao and Xiao-li Kang

    Citation: BMC Ophthalmology 2020 20:32

    Content type: Research article

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  17. To evaluate the prevalence and risk factors associated with myopia and high myopia in children in South Korea.

    Authors: Hyuna Kim, Jin Seok Seo, Woong-Sun Yoo, Gyu-Nam Kim, Rock Bum Kim, Jae Eun Chae, Inyoung Chung, Seong-Wook Seo and Seong Jae Kim

    Citation: BMC Ophthalmology 2020 20:31

    Content type: Research article

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  18. Dr. Gnanasekaran et al. reported the bactericidal activity of various concentrations of povidone iodine (PI) solution in an agar plate experiment of respiratory flora. The study design and the pharmacokinetic ...

    Authors: Jagger Koerner and Andrzej Grzybowski

    Citation: BMC Ophthalmology 2020 20:29

    Content type: Correspondence

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    The original article was published in BMC Ophthalmology 2019 19:62

  19. Corneal infections with antibiotic-resistant microorganisms are an increasingly difficult management challenge and chemically or photochemically cross-linking the cornea for therapy presents a unique approach ...

    Authors: Daeryl E. Amponin, Joanna Przybek-Skrzypecka, Mariya Zyablitskaya, Anna Takaoka, Leejee H. Suh, Takayuki Nagasaki, Stephen L. Trokel and David C. Paik

    Citation: BMC Ophthalmology 2020 20:28

    Content type: Research article

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  20. Due to high prevalence myopia has gained importance in epidemiological studies. Children with early onset are at particular risk of complications associated with myopia, as progression over time might result i...

    Authors: Andrzej Grzybowski, Piotr Kanclerz, Kazuo Tsubota, Carla Lanca and Seang-Mei Saw

    Citation: BMC Ophthalmology 2020 20:27

    Content type: Review

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  21. Dry Eye Disease (DED) is a multifactorial disease of the interpalpebral ocular surface and tear film that leads to discomfort, fatigue and disturbance in vision. DED affects patients’ quality of life and leads...

    Authors: Yousef Shanti, Reham Shehada, May M. Bakkar and Jamal Qaddumi

    Citation: BMC Ophthalmology 2020 20:26

    Content type: Research article

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  22. Radiation therapy (RT) is the treatment of choice in patients with low-grade ocular adenexal mucosa-associated lymphoid tissue lymphoma (OAML) and many of them experience post-RT dry eye with varying severity....

    Authors: Sung Eun Kim, Hee Jung Yang and Suk-Woo Yang

    Citation: BMC Ophthalmology 2020 20:24

    Content type: Research article

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  23. Accurate measurement of intraocular pressure (IOP) after corneal refractive surgery is of great significance to clinic, and comparisons among various IOP measuring instruments are not rare, but there is a lack...

    Authors: Hui Zhang, Zhengtao Sun, Lin Li, Ran Sun and Haixia Zhang

    Citation: BMC Ophthalmology 2020 20:23

    Content type: Research article

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  24. We report a case of uveitis–glaucoma–hyphema (UGH) syndrome in a highly myopic pseudophakic eye with seemingly normal positioning of a two-haptic intraocular lens (IOL).

    Authors: Yu Du, Xiangjia Zhu, Jin Yang, Yinglei Zhang, Lei Cai and Yi Lu

    Citation: BMC Ophthalmology 2020 20:22

    Content type: Case report

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  25. Following the principles of value-based health care, outcomes and processes of daily-practice eye care need to be systematically evaluated. We illustrate an approach that can be used to support data-driven qua...

    Authors: Margriet I. van der Reis, M. Elshout, Tos T. J. M. Berendschot, Yvonne de Jong-Hesse, Carroll A. B. Webers and Jan S. A. G. Schouten

    Citation: BMC Ophthalmology 2020 20:21

    Content type: Research article

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  26. We sought to describe corneal epithelial changes after using epidermal (EGFR) or fibroblast growth factor receptor (FGFR) inhibitors as chemotherapy and to clarify incidence and prognosis.

    Authors: Eunhae Shin, Dong Hui Lim, Jisang Han, Do-Hyun Nam, Keunchil Park, Myung-Ju Ahn, Won Ki Kang, Jeeyun Lee, Jin Seok Ahn, Se-Hoon Lee, Jong-Mu Sun, Hyun Ae Jung and Tae-Young Chung

    Citation: BMC Ophthalmology 2020 20:19

    Content type: Research article

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  27. To evaluate the efficacy and safety of two individualized ranibizumab retreatment schemes in neovascular age-related macular degeneration.

    Authors: Giovanni Staurenghi, Justus G. Garweg, Bianca S. Gerendas, Wayne Macfadden, Boris Gekkiev, Philippe Margaron, Cornelia Dunger-Baldauf and Petr Kolar

    Citation: BMC Ophthalmology 2020 20:18

    Content type: Research article

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  28. To evaluate the macular vessel density (VD) and ganglion cell complex (GCC) thickness in pre-perimetric (PPG) and early perimetric primary open-angle glaucoma (PG) eyes, and to compare the diagnostic ability o...

    Authors: Yiwei Wang, Chen Xin, Meng Li, David L. Swain, Kai Cao, Huaizhou Wang and Ningli Wang

    Citation: BMC Ophthalmology 2020 20:17

    Content type: Research article

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  29. To determine whether diffuse retinal nerve fiber layer (RNFL) defects, identified on red-free fundus photographs, could be identified on optical coherence tomography (OCT) en face structural images and to eval...

    Authors: Abegaile Bartolome Lim, Ji-Hye Park, Jae Hoon Jung, Chungkwon Yoo and Yong Yeon Kim

    Citation: BMC Ophthalmology 2020 20:16

    Content type: Research article

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  30. The concentrations of cytokines in the aqueous humor from neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) may vary. The study was conducted to compare various cy...

    Authors: Huiying Zhou, Xinyu Zhao, Mingzhen Yuan and Youxin Chen

    Citation: BMC Ophthalmology 2020 20:15

    Content type: Research article

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  31. The purpose of this study was to compare the anatomical and visual outcomes of inverted internal limiting membrane (ILM) flap technique and internal limiting membrane peeling in large macular holes (MH).

    Authors: Yu Shen, Xiaoqin Lin, Luyi Zhang and Miaoqin Wu

    Citation: BMC Ophthalmology 2020 20:14

    Content type: Research article

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  32. Tear film stability is the key event in ocular surface diseases. The purpose of this study is to evaluate spatial and temporal progression of the tear film breakup using an automatic non-invasive device.

    Authors: Adriano Guarnieri, Elena Carnero, Anne-Marie Bleau, Nicolás López de Aguileta Castaño, Marcos Llorente Ortega and Javier Moreno-Montañés

    Citation: BMC Ophthalmology 2020 20:12

    Content type: Research article

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  33. To compare the anatomical and functional outcomes of the inverted internal limiting membrane (ILM) flap technique and the complete ILM removal in the treatment of large stage 4 macular hole (MH) > 400 μm and t...

    Authors: Prithvi Ramtohul, Eric Parrat, Danièle Denis and Umberto Lorenzi

    Citation: BMC Ophthalmology 2020 20:11

    Content type: Research article

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  34. Developing objective and repeatable indicators to evaluate the efficacy of PVRL treatment is important. The quantification of vitreous cells is a traditional criterion; however slight changes are difficult to ...

    Authors: Huiying Zhao, Xiaona Wang, Yu Mao and Xiaoyan Peng

    Citation: BMC Ophthalmology 2020 20:10

    Content type: Research article

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  35. Glaucoma is a global public health problem and it is the leading cause of irreversible blindness worldwide. Even though public knowledge of glaucoma is a key for early case identification and prevention of bli...

    Authors: Zewdu Yenegeta, Ayanaw Tsega, Yezinash Addis and Fisseha Admassu

    Citation: BMC Ophthalmology 2020 20:8

    Content type: Research article

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  36. To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Wei Xu, Weijing Cheng, Xiaoyuan Cui and Guoxing Xu

    Citation: BMC Ophthalmology 2020 20:7

    Content type: Research article

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  37. The Valsalva maneuver (VM) is widely used in daily life, and has been reported to cause high intraocular pressure (IOP). This study aimed to assess changes in IOP, the Schlemm’s canal (SC), autonomic nervous s...

    Authors: Li Sun, Wei Chen, Zhiqi Chen, Yan Xiang, Jingmin Guo, Tian Hu, Qiongfang Xu, Hong Zhang and Junming Wang

    Citation: BMC Ophthalmology 2020 20:5

    Content type: Research article

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