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  1. Few case reports have described sildenafil overdose, particularly ingestion of > 1000 mg, and overdose-induced changes in visual function remain unclear. We report retinal morphology, retinal sensitivity, and ...

    Authors: Gen Miura, Takayuki Baba, Ryusuke Hashimoto and Shuichi Yamamoto
    Citation: BMC Ophthalmology 2022 22:216
    Content type: Case report Published on:

  2. Although relationship between the retinal vessel caliber (RVC) and glaucoma is well known, there has been a paucity of information on the effects of glaucoma-related optic nerve head (ONH) structural factors o...

    Authors: Aiko Iwase, Tae Tsutsumi, Ryo Kawasaki, Jun Suehiro, Akihiko Sekine and Makoto Araie
    Citation: BMC Ophthalmology 2022 22:215
    Content type: Research article Published on:

  3. This study was investigated the surgical outcomes of primary rhegmatogenous retinal detachment (RRD) with inferior retinal breaks (IRBs) that were repaired by 25-gauge pars plana vitrectomy (PPV) with air tamp...

    Authors: Yongping Tang, Bo Lin, Jing Chen, Daosen Chen and Ronghan Wu
    Citation: BMC Ophthalmology 2022 22:213
    Content type: Research Published on:

  4. To investigate the prevalence of myopia in Chinese primary school students and their ocular biometrics including axial length (AL), corneal radius of curvature (CRC) and spherical equivalent refraction (SER). ...

    Authors: Yu Yue, Xianmao Liu, Shu Yi, Bo Liu, Hong Yi and Hong Li
    Citation: BMC Ophthalmology 2022 22:212
    Content type: Research Published on:

  5. To report a case of a patient showing bilateral corneal opacities after amantadine chronic treatment for Parkinson’s Disease (PD) and corneal edema associated with intra-epithelial and -endothelial depositions...

    Authors: Michela Cennamo, Francesco Dragotto, Eleonora Favuzza, Alberto Morelli and Rita Mencucci
    Citation: BMC Ophthalmology 2022 22:211
    Content type: Case report Published on:

  6. To evaluate the visual outcome, intraocular pressure control and trabeculectomy survival after phacoemulsification in eyes with prior trabeculectomy in uveitis associated with Vogt-Koyanagi-Harada disease (VKH).

    Authors: Faisal A. Almobarak, Ali H. Alharbi, Ibrahim Aljadaan and Hassan Aldhibi
    Citation: BMC Ophthalmology 2022 22:210
    Content type: Research Published on:

  7. Macular corneal dystrophy is a rare inherited disease of the cornea leading to deposits mainly in the stroma. Affected patients suffer from progressive loss of visual acuity which should be treated with penetr...

    Authors: Caroline Julia Gassel, Jens Martin Rohrbach, Daniel Röck, Karl Ulrich Bartz-Schmidt and Tobias Röck
    Citation: BMC Ophthalmology 2022 22:209
    Content type: Case report Published on:

  9. This study aimed to analyze if the outcome after corneal crosslinking (CXL) in progressive keratoconus patients depends on the stage at which the procedure is performed. This knowledge would help to improve su...

    Authors: Caroline Julia Gassel, Daniel Röck, Eva-Maria Konrad, Gunnar Blumenstock, Karl Ulrich Bartz-Schmidt and Tobias Röck
    Citation: BMC Ophthalmology 2022 22:207
    Content type: Research Published on:

  10. This study aims to investigate the effect of the glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) liraglutide on retinal pathological findings as compared with insulin and hydralazine using an animal...

    Authors: Kazuho Inoue, Shohei Yamada, Seiko Hoshino, Minoru Watanabe, Kenjiro Kimura and Atsuko Kamijo-Ikemori
    Citation: BMC Ophthalmology 2022 22:206
    Content type: Research Published on:

  11. To report the multimodal imaging and treatment of fifteen retinal capillary hemangioblastomas (RCHs) associated with Von Hippel-Lindau syndrome in a monocular patient during a long-term following-up, which sup...

    Authors: Ju Guo, Liping Du, Pengyi Zhou, Xiaohong Guo, Fangfang Dai and Xuemin Jin
    Citation: BMC Ophthalmology 2022 22:205
    Content type: Case report Published on:

  12. Presbyopia is a common progressive vision disorder characterised by an inability to focus on near objects. The emergence of newer treatment options in addition to spectacles or contact lenses highlights the im...

    Authors: Mile Brujic, Paola Kruger, Jeff Todd, Elizabeth Barnes, Mark Wuttke, Flavia Perna and Jorge Aliò
    Citation: BMC Ophthalmology 2022 22:204
    Content type: Research Published on:

  13. To investigate the difference of spherical equivalent (SE) and pupil diameter in adult patients with intermittent exotropia (IXT) under various viewing conditions before and after surgery.

    Authors: Ziyi Qi, Linlin Du, Jun Chen, Xun Xu, Xiangui He and Jun Qiang
    Citation: BMC Ophthalmology 2022 22:203
    Content type: Research Published on:

  15. Congenital anomalies of the pupil are quite varied, including abnormal size, shape, color, response to stimulus, and function. We are here reporting an unusual case presented with the absence of pupillary open...

    Authors: Lancao Hao, Zicheng Ma, Chenjie Song and Siquan Zhu
    Citation: BMC Ophthalmology 2022 22:201
    Content type: Case report Published on:

  18. This study aimed to evaluate macular vessel tortuosity using optical coherence tomography angiography (OCTA) and its association with visual outcomes in eyes undergoing surgery for epiretinal membrane (ERM).

    Authors: Kosuke Miyazawa, Susumu Sakimoto, Masanori Kanai, Akihiko Shiraki, Shizuka Takahashi, Nobuhiko Shiraki, Kazuichi Maruyama, Hirokazu Sakaguchi and Kohji Nishida
    Citation: BMC Ophthalmology 2022 22:198
    Content type: Research Published on:

  19. To evaluate the efficacy of MP-3 microperimeter biofeedback fixation training (MBFT) in vision rehabilitation of low-vision patients affected by macular disease with central vision loss.

    Authors: Tianwei Qian, Xian Xu, Xinyi Liu, Manni Yen, Hao Zhou, Manman Mao, Huiting Cai, Hangqi Shen, Xun Xu, Yuanyuan Gong and Suqin Yu
    Citation: BMC Ophthalmology 2022 22:197
    Content type: Research Published on:

  20. This study is the first part of the “Binocular Vision Anomalies after Cataract Surgery” study that aimed to investigate the impact of cataract surgery on binocular vision status in adults with age-related cata...

    Authors: Qing-Qing Tan, James S. Lewis, Chang-Jun Lan, Xuan Liao, Xiao-Li Tang, Jingyun Wang and Mitchell M. Scheiman
    Citation: BMC Ophthalmology 2022 22:196
    Content type: Research Published on:

  22. Coats disease is a retinal vascular disorder characterized by aneurysms and telangiectasias. Macular fibrosis is a complication of Coats disease that results in vision loss. Macular fibrosis rarely develops in...

    Authors: Tomoka Mizobuchi, Takashi Nishiuchi, Yusaku Miura and Ken Fukuda
    Citation: BMC Ophthalmology 2022 22:194
    Content type: Case report Published on:

  23. To examine an effect of intravitreally applied antibodies against epidermal growth factor family members, namely epiregulin, epigen and betacellulin, on ocular axial elongation.

    Authors: Li Dong, Rui-Heng Zhang, Wen-Da Zhou, Yi-Fan Li, He-Yan Li, Hao-Tian Wu, Xu-Han Shi, Jost. B. Jonas and Wen-Bin Wei
    Citation: BMC Ophthalmology 2022 22:193
    Content type: Research Published on:

  24. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12886-020-01565-z.

    Authors: Yamin Wang, Min Zhang, Ying Sun, Xiaohui Wang, Zhaowei Song, Huazhang Li, Kexin Liu and Zhijian Li
    Citation: BMC Ophthalmology 2022 22:192
    Content type: Retraction Note Published on:

  25. To evaluate the impact of optical coherence tomography (OCT) biomarkers on intravitreal dexamethasone (DEX) implant clinical outcomes in patients with macular edema secondary to retinal vein occlusion (RVO-ME).

    Authors: Verónica Castro-Navarro, Clara Monferrer-Adsuara, Catalina Navarro-Palop, Javier Montero-Hernández and Enrique Cervera-Taulet
    Citation: BMC Ophthalmology 2022 22:191
    Content type: Research Published on:

  27. Wavefront-optimized laser-assisted in situ keratomileusis (LASIK) ablation is the most commonly performed procedure in refractive surgery, but new technologies have become available. Our goal was to compare to...

    Authors: Ermano M. Alves, Adriana F. Lyra, Manuela Tenório, Natália Mesquita, Carolina Bacelar, Afra Montenegro, Lucas Alves and Márcio Alves
    Citation: BMC Ophthalmology 2022 22:189
    Content type: Research Published on:

  31. To evaluate changes in Toll Like Receptors (TLRs) expression at the ocular surface of healthy volunteers within different age groups.

    Authors: Antonio Di Zazzo, Maria De Piano, Marco Coassin, Tommaso Mori, Bijorn Omar Balzamino and Alessandra Micera
    Citation: BMC Ophthalmology 2022 22:185
    Content type: Research article Published on:

  32. Pigmented paravenous retinochoroidal atrophy (PPRCA) is a rare fundus disease characterized by the presence of osteoblast-like pigment, atrophy of retinal pigment epithelium (RPE), and choroid deposition along...

    Authors: Yilin Sun, Jia Li, Li Yu and Yajuan Zheng
    Citation: BMC Ophthalmology 2022 22:184
    Content type: Case report Published on:

  33. So far, few data are available on the relationship between allergic conjunctivitis (AC) and ocular fundus. Whether retinal parameters change in patients with AC remains unknown. In this study, we investigated ...

    Authors: Danni Chen, Rui Li, Dan Huang, Haohai Tong, Xiaoyan Zhao, Wen Yan, Shiya Shen, Hu Liu and Hui Zhu
    Citation: BMC Ophthalmology 2022 22:183
    Content type: Research article Published on:

  34. Virtual reality is being increasingly applied in vision therapy. However, the differences in effectiveness, optimal treatment cycle, and prognosis between virtual reality-based vision therapy and traditional t...

    Authors: Shijin Li, Angcang Tang, Bi Yang, Jianglan Wang and Longqian Liu
    Citation: BMC Ophthalmology 2022 22:182
    Content type: Research Published on:

  36. Amblyopia is a major public health concern. Its screening and management require reliable methods of visual acuity assessment. New technologies offer nowadays many tests available on different app stores for s...

    Authors: Noémie Stoll, Elsa Di Foggia, Claude Speeg-Schatz, Hélène Meunier, Adam Rimele, Pascal Ancé, Pierre-Henri Moreau and Arnaud Sauer
    Citation: BMC Ophthalmology 2022 22:180
    Content type: Research article Published on:

  37. Stevens-Johnson syndrome (SJS) is an abnormal immune-response causing extensive exfoliation of the mucocutaneous tissue including conjunctiva. While several factors are associated with the alteration of conjun...

    Authors: Jayoon Moon, Yunjin Lee, Chang Ho Yoon and Mee Kum Kim
    Citation: BMC Ophthalmology 2022 22:179
    Content type: Research Published on:

  38. Diagnostic vitrectomy is an important method for evaluating uveitis, and its diagnostic utility is high regardless of whether the uveitis is infectious or non-infectious. The course of diagnostic vitreous surg...

    Authors: Atsushi Sakai, Mizuki Tagami, Norihiko Misawa, Manabu Yamamoto, Takeya Kohno and Shigeru Honda
    Citation: BMC Ophthalmology 2022 22:178
    Content type: Research Published on:

  39. To confirm the association between treatment-zone (TZ) decentration and axial length growth (ALG) in children who underwent orthokeratology; and to explore the association between TZ decentration and relative ...

    Authors: Weiping Lin, Tianpu Gu, Hua Bi, Bei Du, Bin Zhang and Ruihua Wei
    Citation: BMC Ophthalmology 2022 22:177
    Content type: Research Published on:

  40. Diabetic retinopathy is a disease seen with microvascular complications as a result of hyperglycemia and insulin resistance. Alarin and Adipsin are molecules with a role in energy and glucose metabolism. The a...

    Authors: Fatih Cem Gül, Sabiha Güngör Kobat, Fatih Çelik, Süleyman Aydin and Ramazan Fazıl Akkoç
    Citation: BMC Ophthalmology 2022 22:176
    Content type: Research Published on:

  46. The microbiome could trigger inflammation leading to epigenetic changes and is involved in the pathophysiology of eye diseases; however, its effect on uveitic glaucoma (UG) has not been fully investigated. Thi...

    Authors: Jong Hoon Shin, Ji-Woong Lee, Su-Ho Lim, Byung Woo Yoon, Young Lee and Je Hyun Seo
    Citation: BMC Ophthalmology 2022 22:170
    Content type: Research Published on:

  47. We report for the first time a way to predict the 2-dimensional extension of an internal limiting membrane (ILM) defect by detecting the area with dissociated optic nerve fiber layer (DONFL)-like spots in the ...

    Authors: Yuichiro Ishida, Naomichi Ota, Kotaro Tsuboi and Motohiro Kamei
    Citation: BMC Ophthalmology 2022 22:169
    Content type: Case report Published on:

  48. Posterior ischemic optic neuropathy (PION) is a rare cause of visual loss, especially in young patients who are more prone to inflammatory demyelinating optic neuritis (ON) compared to other types of optic neu...

    Authors: Tzu-Hsuan Yang and Muh-Chiou Lin
    Citation: BMC Ophthalmology 2022 22:168
    Content type: Case report Published on:

  49. Phacoemulsification using phaco-chop technique has many challenging features in cataract patients with highly liquefied vitreous. This study aimed to compare the intraoperative parameters and safety between pr...

    Authors: Jing Zhao, Zhouyue Li, Yu Liu, Xiaotong Han and Shengsong Huang
    Citation: BMC Ophthalmology 2022 22:167
    Content type: Research Published on:

  50. To examine the potential utility of five multifocal pupillographic objective perimetry (mfPOP) protocols, in the assessment of early diabetic retinopathy (DR) and generalised diabetes-related tissue injury in ...

    Authors: Faran Sabeti, Corinne F. Carle, Christopher J. Nolan, Alicia J. Jenkins, Andrew C. James, Lauren Baker, Caitlin E. Coombes, Veronica Cheung, Melody Chiou and Ted Maddess
    Citation: BMC Ophthalmology 2022 22:166
    Content type: Research Published on:
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