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  1. EPO (erythropoietin) and PDGF (platelet derived growth factor) families are thought to be associated with angiogenesis under hypoxic condition. The sharp rise of intraocular pressure in acute primary angle clo...

    Authors: Jing Wang, Ming-shui Fu, Min-wen Zhou, Bi-lian Ke, Zhi-hua Zhang and Xun Xu
    Citation: BMC Ophthalmology 2021 21:297
    Content type: Research article Published on:

  2. There is a relative lack of information on the incidence and treatment of vision problems in Prader-Willi syndrome (PWS). Using data from the Global PWS Registry, we performed a cross-sectional study of vision...

    Authors: Jessica E. Bohonowych, Caroline J. Vrana-Diaz, Jennifer L. Miller, Shawn E. McCandless and Theresa V. Strong
    Citation: BMC Ophthalmology 2021 21:296
    Content type: Research Published on:

  4. To analyze the long-term effects of persistent subretinal fluid (SRF) on visual/anatomic outcomes according to the type of macular neovascularization (MNV) during relaxed treat-and-extend regimen with anti-vas...

    Authors: Kyung Tae Kim, Ju Byung Chae, Seungheon Lee, Eoi Jong Seo and Dong Yoon Kim
    Citation: BMC Ophthalmology 2021 21:294
    Content type: Research Published on:

  6. To compare the correction effect and optical quality after small-incision lenticule extraction (SMILE) and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia.

    Authors: Yewei Yin, Ying Lu, Aiqun Xiang, Yanyan Fu, Yang Zhao, Yuanjun Li, Tu Hu, Kaixuan Du, Shengfa Hu, Qiuman Fu, Xiaoying Wu and Dan Wen
    Citation: BMC Ophthalmology 2021 21:292
    Content type: Research Published on:

  7. This study aimed to present a simple method for evaluating transient eye closure (TEC) evoked by bright light and find the agreement between TEC and photosensitivity. We also assessed the associated factors wi...

    Authors: Won Jong Choi, Yeonji Jang, Seong-Joon Kim and Jae Ho Jung
    Citation: BMC Ophthalmology 2021 21:291
    Content type: Research article Published on:

  9. Retinitis pigmentosa (RP) is a heterogeneous group of inherited ocular diseases that result in progressive retinal degeneration. This study aims to describe different Swept-source Optical Coherence Tomographic...

    Authors: Orjowan Shalabi, Zaher Nazzal, Muath Natsheh, Salam Iriqat, Michel Michaelides, Muyassar Ghanem, Alice Aslanian, Yahya Alswaiti and Alaa AlTalbishi
    Citation: BMC Ophthalmology 2021 21:289
    Content type: Research Published on:

  11. Topiramate (TPM) is a drug commonly used by neurophysicians and psychiatrists for a plethora of indications. Topiramate has been reported to induce acute angle closure glaucoma as an adverse effect. However, t...

    Authors: Mudit Tyagi, Shashwat Behera, Sirisha Senthil, Rajeev R. Pappuru, Vikas Ambiya and Siddharth Dikshit
    Citation: BMC Ophthalmology 2021 21:287
    Content type: Case report Published on:

  13. Corneal dystrophies are a group of rare, inherited disorders that are usually bilateral, symmetric, slowly progressive, and not related to environmental or systemic factors. The majority of publications presen...

    Authors: Anna Nowińska, Edyta Chlasta-Twardzik, Michał Dembski, Ewa Wróblewska-Czajka, Klaudia Ulfik-Dembska and Edward Wylęgała
    Citation: BMC Ophthalmology 2021 21:285
    Content type: Case report Published on:

  14. To report the first Italian case of hypotrichosis with juvenile macular dystrophy complicated by macular neovascularization diagnosed through multimodal imaging.

    Authors: Giovanna Carnovale-Scalzo, Adriano Carnevali, Gabriele Piccoli, Domenico Ceravolo, Donatella Bruzzichessi, Rodolfo Iuliano, Rossana Tallerico, Valentina Gatti, Giuseppe Giannaccare and Vincenzo Scorcia
    Citation: BMC Ophthalmology 2021 21:284
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Ophthalmology 2024 24:26

  15. Myopia has become a global public health problem. Children with early onset of myopia are at particular risk of complications associated with myopia. Younger children and children with greater initial myopic r...

    Authors: Lei Liu, Rui Li, Dan Huang, Xiao Lin, Hui Zhu, Yue Wang, Xiaoyan Zhao, Xiaohan Zhang and Hu Liu
    Citation: BMC Ophthalmology 2021 21:283
    Content type: Research article Published on:

  17. Dysfunction of lacrimal gland (LG) gains increasing attention in patients with thyroid-associated ophthalmopathy (TAO), while the underlying pathological change is still not fully established. This study aimed...

    Authors: Lu Chen, Hao Hu, Wen Chen, Qian Wu, Jiang Zhou, Huan-Huan Chen, Xiao-Quan Xu, Hai-Bin Shi and Fei-Yun Wu
    Citation: BMC Ophthalmology 2021 21:281
    Content type: Research Published on:

  18. To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM).

    Authors: Juan Gros-Otero, Samira Ketabi, Rafael Cañones-Zafra, Montserrat Garcia-Gonzalez, Cesar Villa-Collar, Santiago Casado and Miguel A. Teus
    Citation: BMC Ophthalmology 2021 21:280
    Content type: Research Published on:

  20. Globally, ocular morbidity has emerged as a major public concern with at least 2.2 billion people having vision impairment or blindness. Prisoners (inmates) tend to have limited access to health care especiall...

    Authors: Charity Zalwango, Pauline Ayebare, Pius Mwanja, Erima Denis, Moses Kasadhakawo, Micheal Mugerwa and Anne Ampaire
    Citation: BMC Ophthalmology 2021 21:278
    Content type: Research article Published on:

  21. Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. ...

    Authors: Mohamed Belmouhand, Christina Eckmann-Hansen, Tomas Ilginis, Eva Birgitte Leinøe, Bo Kok Mortensen and Michael Larsen
    Citation: BMC Ophthalmology 2021 21:277
    Content type: Case report Published on:

  22. Non-arteritic ischaemic optic neuropathy (NAION) is a rare but harmful complication of prone positioning. Prone mechanical ventilation is a therapeutic strategy which has been used extensively during the COVID...

    Authors: Kirsty Michelle Clarke, Vivi Riga, Amy-lee Shirodkar and Joel Meyer
    Citation: BMC Ophthalmology 2021 21:276
    Content type: Case report Published on:

  23. Superficial eye disorders are one of the most common complications of improper eye care in intensive care units that can lead to corneal ulcers and permanent eye damage. The aim of this study was to determine ...

    Authors: Azam Pourghaffari Lahiji, Mohsen Gohari, Samaneh Mirzaei and Khadijeh Nasiriani
    Citation: BMC Ophthalmology 2021 21:275
    Content type: Research Published on:

  25. PreserFlo® MicroShunt (PM) (also known as InnFocus® MicroShunt) is a subconjunctival stent implanted ab externo via a minimally invasive surgical procedure. The current indication is progressive, mild to moderate...

    Authors: Roxane Bunod, Mathieu Robin, Juliette Buffault, Chafik Keilani, Antoine Labbé and Christophe Baudouin
    Citation: BMC Ophthalmology 2021 21:273
    Content type: Case report Published on:

  26. This report describes the design and methodology of the “Eyes of Africa: The Genetics of Blindness,” a collaborative study funded through the Human Heredity and Health in Africa (H3Africa) program of the Natio...

    Authors: Olusola Olawoye, Chimdi Chuka-Okosa, Onoja Akpa, Tony Realini, Michael Hauser and Adeyinka Ashaye
    Citation: BMC Ophthalmology 2021 21:272
    Content type: Study protocol Published on:

  27. To identify the ocular surface changes of ocular graft-versus-host disease (GVHD) using anterior segment optical coherence tomography (AS-OCT) and examine the efficacy of disposable bandage soft contact lens (...

    Authors: Yi-Chen Sun, Yoshihiro Inamoto, Ruikang K. Wang, Stephanie J. Lee, Kai-Feng Hung and Tueng T. Shen
    Citation: BMC Ophthalmology 2021 21:271
    Content type: Research Published on:

    The Correction to this article has been published in BMC Ophthalmology 2022 22:38

  28. Intermittent exotropia (IXT) is the most common form of exotropia in children. In addition to cosmetic effects and loss of stereoscopic function, IXT may negatively impact the psychological well-being of child...

    Authors: Danyi Mao, Jing Lin, Lina Chen, Jiying Luo and Jianhua Yan
    Citation: BMC Ophthalmology 2021 21:270
    Content type: Research article Published on:

  29. To investigate the diagnostic value of choroidal thickness in the definition of pachychoroid neovasculopathy (PNV), especially in eyes treated with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Benedikt Schworm, Nikolaus Luft, Leonie F. Keidel, Thomas C. Kreutzer, Tina R. Herold, Siegfried G. Priglinger and Jakob Siedlecki
    Citation: BMC Ophthalmology 2021 21:269
    Content type: Research article Published on:

  30. With the rapid development of intraocular collamer lens (ICL) operation, it is foreseeable that we will encounter a large number of glaucoma patients with ICL implantation history. However, our current underst...

    Authors: Wei Wei, Xueqing Yu, Lu Yang, Chan Xiong and Xu Zhang
    Citation: BMC Ophthalmology 2021 21:268
    Content type: Case report Published on:

  31. Demographic, systemic and ocular factors may impact macular ganglion cell–inner plexiform layer (GCIPL) thickness measurements. This study aimed to investigate the influences of multiple potential determinants...

    Authors: Xiaoyu Xu, Hui Xiao, Kunbei Lai, Xinxing Guo, Jingyi Luo and Xing Liu
    Citation: BMC Ophthalmology 2021 21:267
    Content type: Research article Published on:

  32. Micropulse transscleral cyclophotocoagulation (MP-CPC) is a technique that has been approved in recent years to treat glaucoma. MP-CPC causes anterior chamber inflammation; a relationship with reduced intraocu...

    Authors: Akitoshi Kimura, Kei-Ichi Nakashima and Toshihiro Inoue
    Citation: BMC Ophthalmology 2021 21:266
    Content type: Research Published on:

  33. Occupational predisposition to dry eye disease is known. Simultaneous exposure to multiple factors may pose more risk. Street sweepers are exposed to sunlight in addition to dust which all sweepers are exposed...

    Authors: Chigozie I. Echieh, Bassey A. Etim, Chidiebere Peter Echieh, Taiwo Oyeniyi and Jeff Ajewole
    Citation: BMC Ophthalmology 2021 21:265
    Content type: Research article Published on:

  34. Visual fixation may be affected in amblyopic patients and, moreover, its stability may be associated with the effects of amblyopic treatments on visual performance in patients with strabismus. Therefore, fixat...

    Authors: Otto Alexander Maneschg, Mirella Telles Salgueiro Barboni, Zoltán Zsolt Nagy and János Németh
    Citation: BMC Ophthalmology 2021 21:264
    Content type: Research Published on:

  36. Glaucomatous eyes often show strong intraocular pressure (IOP) fluctuations and individual measurements at different time points are necessary for personalized therapy. To survey IOP variations 48-hours diurna...

    Authors: Marion Zimmermann, Bert C. Giers, Anna Beck, Katharina Bell, Herwig Zimmermann, Marlene Hechtner, Esther M. Hoffmann, Norbert Pfeiffer and Katrin Lorenz
    Citation: BMC Ophthalmology 2021 21:262
    Content type: Research article Published on:

  37. To evaluate microstructural changes in the meibomian glands (MGs) in patients with active and inactive Graves’ orbitopathy (GO), using in vivo confocal microscopy (IVCM), and to investigate the correlations be...

    Authors: Shengnan Cheng, Yueqi Yu, Jin Chen, Lin Ye, Xinghua Wang and Fagang Jiang
    Citation: BMC Ophthalmology 2021 21:261
    Content type: Research article Published on:

  38. Our study aimed to explore the prevalence and risk factors of refractive error (RE) in Han and Tibetan population aged 50–79 years in Xining and surrounding areas in Qinghai Province on Qinghai-Tibet Plateau.

    Authors: Meng Wang, Linyang Gan, Jiantao Cui, Guangliang Shan, Ting Chen, Xianghua Wang, Yuhan Wang, Li Pan, Zhanquan Li, Sen Cui, Airong Yang, Wenfang Li, Guoqiang Jia, Ximing Han, Huijing He, Yong Zhong…
    Citation: BMC Ophthalmology 2021 21:260
    Content type: Research Published on:

  39. Diabetic retinopathy is the most common microvascular complication of diabetes; however, early changes in retinal microvessels are difficult to detect clinically, and a patient’s vision may have begun to deter...

    Authors: Xinyue Li, Yu Yu, Xueting Liu, Yan Shi, Xin Jin, Yanyan Zhang, Shuo Xu, Nan Zhang, Li Dong, Sujun Zhou, Yingbin Wang, Yiheng Ding, Zhen Song and Hong Zhang
    Citation: BMC Ophthalmology 2021 21:259
    Content type: Research Published on:

  40. During the coronavirus disease 2019 (COVID-19) epidemic, due to the traffic blockade and the shortage of medical resources, more and more premature infants could not receive timely and effective ROP screening,...

    Authors: Zheng Guo, Nan Ma, Yixuan Wu, Hua Yuan, Wanjun Luo, Lingkong Zeng, Hong Jie and Shilian Li
    Citation: BMC Ophthalmology 2021 21:258
    Content type: Research Published on:

  42. To evaluate the necessity of cycloplegia for epidemiological studies of refraction in Chinese young adults (aged 17–22 years) with dark irises, and to compare the cycloplegic effects of 1% cyclopentolate and 0...

    Authors: Ruxia Pei, Zhuzhu Liu, Hua Rong, Liqiong Zhao, Bei Du, Na Jin, Hongmei Zhang, Biying Wang, Yi Pang and Ruihua Wei
    Citation: BMC Ophthalmology 2021 21:256
    Content type: Research article Published on:

  43. Previous studies have demonstrated that strabismus amblyopia can result in markedly brain function alterations. However, the differences in spontaneous brain activities of strabismus amblyopia (SA) patients st...

    Authors: Shuang Zhang, Gui-Ping Gao, Wen-Qing Shi, Biao Li, Qi Lin, Hui-Ye Shu and Yi Shao
    Citation: BMC Ophthalmology 2021 21:255
    Content type: Research Published on:

  46. To describe the longitudinal changes in retinal neovascularization elsewhere (NVE) as observed on optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR) treated by panretin...

    Authors: H. E. Feng, Y. U. Weihong and Fangtian Dong
    Citation: BMC Ophthalmology 2021 21:252
    Content type: Research Published on:

  48. The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymo...

    Authors: Ine Lambert, Giuseppe Fasolino, Gil Awada, Robert Kuijpers, Marcel ten Tusscher and Bart Neyns
    Citation: BMC Ophthalmology 2021 21:250
    Content type: Case report Published on:

  49. Eye injury is a serious worldwide public health problem that may cause blindness. In children, blindness has functional impact and psychosocial implications. As indicated in many worldwide studies, identificat...

    Authors: Valeria D’Antone, Diana Cristina Palencia Flórez, Claudia Juliana Lopez García, Flor De María Cáceres Manrique and Nahyr López Barbosa
    Citation: BMC Ophthalmology 2021 21:248
    Content type: Research Published on:
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