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  1. In diabetic eyes, various choroidal abnormalities are noted in addition to changes in the retinal circulation, and the risk of increased aqueous flare and retinal thickening after cataract surgery is higher in...

    Authors: Yasuko Ikegami, Miyuki Takahashi and Kana Amino
    Citation: BMC Ophthalmology 2020 20:102
    Content type: Research article Published on:

  2. Pseudoduplication of the optic disc is a rare clinical condition that is characterized by a circumscribed, disc-like lesion with radiating vessels but only one normal optic nerve. We report a rare case that in...

    Authors: Liuhui Huang, Qi Zhang, Haiying Jin and Peiquan Zhao
    Citation: BMC Ophthalmology 2020 20:101
    Content type: Case report Published on:

  3. The aim of this study was to review the demographic and characteristic distribution data of serious rural pediatric eye injuries in Wenzhou and Changsha, located in Zhejiang Province in East China and Hunan Pr...

    Authors: Chunyan Li, Yaoyao Lin, Haishao Xiao, Huan Lin, Yanyan Chen and Minhui Dai
    Citation: BMC Ophthalmology 2020 20:100
    Content type: Research article Published on:

  4. To evaluate the prevalence of blepharoptosis among Korean adults and the characteristics of blepharoptosis patients, and to determine an appropriate age threshold for recommending blepharoptosis evaluation.

    Authors: Ji-Sun Paik, Kyungdo Han, Suk-Woo Yang, Yongkyu Park, Kyungsun Na, Wonkyung Cho, Su-Kyung Jung and Sungeun Kim
    Citation: BMC Ophthalmology 2020 20:99
    Content type: Research article Published on:

  7. Systemic lupus erythematosus (SLE) can directly affect various part of the ocular system, but there was no comprehensive analysis of ophthalmic disorders of patients with SLE using population-based data. The a...

    Authors: Chun-Shuo Hsu, Chia-Wen Hsu, Ming-Chi Lu and Malcolm Koo
    Citation: BMC Ophthalmology 2020 20:96
    Content type: Research article Published on:

  8. This study aimed to investigate the pre- and post-surgery reading ability in patients with idiopathic epiretinal membrane (ERM) to evaluate whether measurement of reading performance is a helpful test in addit...

    Authors: Hiroki Mieno, Kentaro Kojima, Kazuhito Yoneda, Fumie Kinoshita, Rentaro Mizuno, Shinnosuke Nakaji and Chie Sotozono
    Citation: BMC Ophthalmology 2020 20:95
    Content type: Research article Published on:

  9. Hematologic malignancies occasionally cause serous retinal detachment (SRD); however, its pathogenesis remains unclear. Here we present the imaging characteristics of metastatic choroidal lymphoma masquerading...

    Authors: Kanae Fukutsu, Kenichi Namba, Daiju Iwata, Kazuomi Mizuuchi, Satoru Kase, Kayo Suzuki, Hiroshi Shimizu, Yukiko Shibata, Fumihiko Yamawaki, Masahiro Onozawa and Susumu Ishida
    Citation: BMC Ophthalmology 2020 20:94
    Content type: Case report Published on:

  11. Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) tech...

    Authors: Wen-ping Song, Si Zheng, Hong-juan Yao, Xiao-fei Zhou, Rui Li, Cheng-yue Zhang, Jun-yang Zhao, Lie-wei Wang, Rong-guang Shao and Liang Li
    Citation: BMC Ophthalmology 2020 20:92
    Content type: Research article Published on:

  12. To compare vision-related quality of life (VRQOL) between acute and chronic Central serous chorioretinopathy (CSC) and correlate this with Cohen’s Perceived Stress Scale (PSS) questionnaire.

    Authors: Meenakshi Kumar, Elon H. C. van Dijk, Rajiv Raman, Pooja Mehta, Camiel J. F. Boon, Abhilash Goud, Seelam Bharani and Jay Chhablani
    Citation: BMC Ophthalmology 2020 20:90
    Content type: Research article Published on:

  13. We aimed to demonstrate the contribution of anti-inflammatory and anti-virulence effects of azithromycin (AZM) in ocular surface infection treatment.

    Authors: Kana Ikemoto, Shinya Kobayashi, Yu Haranosono, Seiko Kozai, Tomoyuki Wada, Hideki Tokushige and Akio Kawamura
    Citation: BMC Ophthalmology 2020 20:89
    Content type: Research article Published on:

  14. To compare the anterior biometrics in eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chro...

    Authors: Xiaoli Xing, Liangyu Huang, Fang Tian, Yan Zhang, Yingjuan Lv, Wei Liu and Aihua Liu
    Citation: BMC Ophthalmology 2020 20:87
    Content type: Research article Published on:

  15. Postoperative nausea and vomiting (PONV) are common side-effects following strabismus surgery. The present study aimed to compare the effects of different doses of dexmedetomidine (DEX) on PONV incidence in pe...

    Authors: Shuangshuang Li, Tingjie Liu, Junming Xia, Jie Jia and Wenxian Li
    Citation: BMC Ophthalmology 2020 20:86
    Content type: Research article Published on:

  16. The aim of this study was to explore the differences in terms of tear film and meibomian glands (MGs) between young Asian soft contact lens (CL) wearers and non-wearers.

    Authors: Tianpu Gu, Lu Zhao, Zhuzhu Liu, Shaozhen Zhao, Hong Nian and Ruihua Wei
    Citation: BMC Ophthalmology 2020 20:84
    Content type: Research article Published on:

  18. The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting ...

    Authors: Tianrui He, Yi Zhu and Jibo Zhou
    Citation: BMC Ophthalmology 2020 20:82
    Content type: Research article Published on:

  19. Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates...

    Authors: Marc Labetoulle, Anders Behndig, Marie-José Tassignon, Rudy Nuijts, Rita Mencucci, José Luis Güell, Uwe Pleyer, Jacek Szaflik, Paul Rosen, Alain Bérard, Frédéric Chiambaretta and Béatrice Cochener-Lamard
    Citation: BMC Ophthalmology 2020 20:81
    Content type: Research article Published on:

  20. Young adults with type 2 diabetes (aged 18–39 years) are at risk of early onset and rapid progression of diabetic retinopathy, the leading cause of blindness and vision loss in working age adults. Early detect...

    Authors: Amelia J. Lake, Jessica L. Hateley-Browne, Gwyneth Rees and Jane Speight
    Citation: BMC Ophthalmology 2020 20:80
    Content type: Research article Published on:

  22. Posterior capsule opacification (PCO) after cataract surgery is influenced by intraocular lens (IOL) design and material. The following is an ex vivo comparison of PCO between the Clareon vs. the AcrySof IOL i...

    Authors: Anna Hillenmayer, Christian M. Wertheimer, Stefan Kassumeh, Annabel von Studnitz, Nikolaus Luft, Andreas Ohlmann, Siegfried Priglinger and Wolfgang J. Mayer
    Citation: BMC Ophthalmology 2020 20:77
    Content type: Research article Published on:

  23. The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in S...

    Authors: Daniel Beck, Martin Galea, Cheng Yi Loo, Conrad Schmoll, Frederick R. Burgess, Donald Montgomery and Andrew J. Tatham
    Citation: BMC Ophthalmology 2020 20:76
    Content type: Research article Published on:

  24. Presence of corneal cystine crystals is the main ocular manifestation of cystinosis, although controversial findings concerning the corneal layer with the highest density have been reported. The aim of this st...

    Authors: Anita Csorba, Erika Maka, Otto Alexander Maneschg, Attila Szabó, Nóra Szentmáry, Mária Csidey, Miklós Resch, László Imre, Krisztina Knézy and Zoltán Zsolt Nagy
    Citation: BMC Ophthalmology 2020 20:73
    Content type: Research article Published on:

  25. Primary objective of this review was to measure compliance with spectacle use in children with refractive errors. Secondary objective was to understand the reasons for non-compliance.

    Authors: Nonita Dhirar, Sankalp Dudeja, Mona Duggal, Parul Chawla Gupta, Nishant Jaiswal, Meenu Singh and Jagat Ram
    Citation: BMC Ophthalmology 2020 20:71
    Content type: Research article Published on:

  26. Usher syndrome (USH) is the most prevalent cause of the human genetic deafness and blindness. USH type II (USH2) is the most common form of USH, and USH2A is the major pathogenic gene for USH2. For expanding the ...

    Authors: Chenhao He, Xinyu Liu, Zilin Zhong and Jianjun Chen
    Citation: BMC Ophthalmology 2020 20:70
    Content type: Research article Published on:

  27. To evaluate the safety and efficacy of a treat-and-extend protocol of aflibercept for cystoid macular oedema (CMO) secondary to central retinal vein occlusion (CRVO).

    Authors: Roderick O’Day, Noha Ali, Lyndell L. Lim, Sukhpal Sandhu, Thuy Chau and Sanjeewa Wickremasinghe
    Citation: BMC Ophthalmology 2020 20:69
    Content type: Research article Published on:

  28. Congenital mydriasis and retinal arteriolar tortuosity are associated with the life-threatening multisystemic smooth muscle dysfunction syndrome (MSMDS) due to mutations in the gene, ACTA2, which encodes alpha-sm...

    Authors: Aisling B. Mc Glacken-Byrne, David Prentice, Danial Roshandel, Michael R. Brown, Philip Tuch, Kyle S.-Y. Yau, Padma Sivadorai, Mark R. Davis, Nigel G. Laing and Fred K. Chen
    Citation: BMC Ophthalmology 2020 20:68
    Content type: Case report Published on:

  29. It is well known that the biomechanical properties change after LASIK refractive surgery. One reason is the impact of flap creation on the residual stroma. The results have revealed that the change is closely ...

    Authors: Lihua Fang, Yan Wang, Ruizhi Yang, Sijing Deng, Jiahao Deng and Linsun Wan
    Citation: BMC Ophthalmology 2020 20:67
    Content type: Research article Published on:

  30. Glaucoma drainage device (GDD) implantation in the anterior chamber are associated with corneal complications. We describe a novel technique to implant GDD tubes in the posterior chamber of pseudophakic eyes.

    Authors: Javier Moreno-Montañés, Concepción Guirao-Navarro and Francisco Argüeso
    Citation: BMC Ophthalmology 2020 20:66
    Content type: Technical advance Published on:

  31. Alveolar soft part sarcoma (ASPS) is a clinically and morphologically distinct malignant soft tissue tumour. It occurs mostly in the lower extremities in adults. The purpose of our study was to describe the re...

    Authors: Yujiao Wang, Baixue Du, Mei Yang and Weimin He
    Citation: BMC Ophthalmology 2020 20:60
    Content type: Case report Published on:

  32. To report an unusual case of light-chain (AL) amyloidosis with progressive bilateral chorioretinal abnormalities documented with short-wavelength autofluorescence, SD-OCT, fluorescein and indocyanine green ang...

    Authors: Edouard Augstburger, José-Alain Sahel and Isabelle Audo
    Citation: BMC Ophthalmology 2020 20:59
    Content type: Case report Published on:

  34. Previously, we showed that serum malondialdehyde (MDA) was significantly higher in patients with neovascular age-related macular degeneration (nAMD) than in those without AMD. The Diacron reactive oxygen metab...

    Authors: Toshiyuki Matsuura, Hiroki Kaneko, Kei Takayama, Rei Shibata, Keiko Kataoka, Seina Ito, Taichi Tsunekawa, Hideyuki Shimizu, Ayana Suzumura, Rina Namba, Yasuki Ito, Toyoaki Murohara and Hiroko Terasaki
    Citation: BMC Ophthalmology 2020 20:56
    Content type: Research article Published on:

  35. Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic un...

    Authors: Weiming Yan, Pan Long, Dongyu Wei, Weihua Yan, Xiangrong Zheng, Guocang Chen, Jiancong Wang, Zuoming Zhang, Tao Chen and Meizhu Chen
    Citation: BMC Ophthalmology 2020 20:55
    Content type: Research article Published on:

  37. To evaluate the optical coherence tomography (OCT) features of retinal lesions in Chinese patients with endogenous Candida endophthalmitis (ECE).

    Authors: Hong Zhuang, Xinyi Ding, Fengjuan Gao, Ting Zhang, Yingqin Ni, Qing Chang and Gezhi Xu
    Citation: BMC Ophthalmology 2020 20:52
    Content type: Research article Published on:

    The Correspondence to this article has been published in BMC Ophthalmology 2020 20:283

  38. Knowing the pattern and presentation of the diseases is critical for management strategies. To inform eye-care policy we quantified the pattern of vitreo-retinal (VR) diseases presenting at the national referr...

    Authors: Bhim B. Rai, Michael G. Morley, Paul S. Bernstein and Ted Maddess
    Citation: BMC Ophthalmology 2020 20:51
    Content type: Research article Published on:

  39. Corneal densitometry, which is also known as corneal backscattering, is a surrogate measure of corneal clarity. The purpose of the study was to investigate the changes in corneal densitometry (CD) after implan...

    Authors: Xun Chen, Yang Shen, Haipeng Xu, Xiaoying Wang and Xingtao Zhou
    Citation: BMC Ophthalmology 2020 20:50
    Content type: Research article Published on:

  40. Diagnosis and follow-up of retinal diseases may be improved if the thickness of the various retinal layers, in addition to the total retinal thickness, is taken into account. Here we measured the thickness of ...

    Authors: Qian Wang, Wen Bin Wei, Ya Xing Wang, Yan Ni Yan, Jing Yan Yang, Wen Jia Zhou, Szy Yann Chan, Liang Xu and Jost B. Jonas
    Citation: BMC Ophthalmology 2020 20:49
    Content type: Research article Published on:

  42. Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study ...

    Authors: Cynthia Owsley, Thomas Swain, Rong Liu, Gerald McGwin Jr and Mi Young Kwon
    Citation: BMC Ophthalmology 2020 20:47
    Content type: Research article Published on:

  44. To investigate the prevalence of pterygium and associated factors in Han and Mongolian adults at four survey sites in Inner Mongolia, China.

    Authors: Yuhan Wang, Guangliang Shan, Linyang Gan, Yonggang Qian, Ting Chen, Hailing Wang, Xiaodan Pan, Wenrui Wang, Li Pan, Xia Zhang, Meng Wang, Jin Ma and Yong Zhong
    Citation: BMC Ophthalmology 2020 20:45
    Content type: Research article Published on:

  45. Rapamycin (RAPA) is a potent angiogenic inhibitor and the aim of this study is to identify the inhibitory effect of RAPA on retinal neovascularization (RNV) in experimental oxygen-induced retinopathy (OIR).

    Authors: Feng Jiang, Ying Wang, Shufang Du, Heng Jin and Jindong Han
    Citation: BMC Ophthalmology 2020 20:44
    Content type: Research article Published on:

  46. To investigate the effect of intravitreal conbercept (IVC) injections on the incidence of postoperative vitreous hemorrhage (VH) in eyes undergoing surgery for severe proliferative diabetic retinopathy.

    Authors: Tingting Jiang, Junxiang Gu, Peijun Zhang, Wenwen Chen and Qing Chang
    Citation: BMC Ophthalmology 2020 20:43
    Content type: Research article Published on:

  47. Optical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and disti...

    Authors: Yong Wang, Jinling Zhang, Miaomiao Qin, Jianguo Miao, Wei Chen, Yemeng Huang, Jian Wu, Yu Guan and Huaijin Guan
    Citation: BMC Ophthalmology 2020 20:42
    Content type: Research article Published on:

  48. Previous studies of internal graft-host malappositions have not dealt with the precise ways in which each malapposition affected post-penetrating keratoplasty (post-PK) visual outcomes. In this study, we revie...

    Authors: Yujin Zhao, Hong Zhuang, Jiaxu Hong, Lijia Tian and Jianjiang Xu
    Citation: BMC Ophthalmology 2020 20:41
    Content type: Research article Published on:
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