Skip to main content
Download PDF

Trifocal diffractive intraocular lens implantation in patients after previous corneal refractive laser surgery for myopia

BMC Ophthalmology volume 20, Article number: 293 (2020) Cite this article

Abstract

Background

With the difficulties in IOL power calculation and the potential side effects occurring postoperatively, multifocal IOL implantation after previous corneal refractive surgery are rarely reported especially for the trifocal IOL. Herein we report the clinical observation of trifocal IOL implantation in patients with previous myopia excimer laser correction. In this study, a multi-formula average method was performed for the IOLs power calculation to improve the accuracy. Visual and refractive outcomes were analyzed, and the subjective quality of patients’ life was evaluated by questionnaires survey.

Methods

This retrospective case series included patients with previous myopia excimer laser correction who underwent femtosecond laser assisted phacoemulsification and trifocal IOL (AT LISA tri 839 MP) implantation. Follow-up was done at 1-day, 1-month and 3-month to assess the visual outcomes. Outcome measures were uncorrected distance, intermediate and near visual acuity (UDVA, UIVA, UNVA), manifest refraction, defocus curve, and subjective quality of vision.

Results

Twenty-one Eyes from sixteen patients (14 eyes with previous laser in situ keratomileusis and 7 eyes with previous photorefractive keratectomy) were included. Mean postoperative spherical equivalent (SE) at 3-month was − 0.56 D ± 0.49 SD, wherein, 10 eyes (47.6%) were within ±0.50 D of the desired emmetropia and 19 eyes (90.5%) were within ±1.0 D. Mean monocular UDVA, UIVA and UNVA (logMAR) at last visit were 0.02 ± 0.07, 0.10 ± 0.10, and 0.15 ± 0.11 respectively. Three patients (19%) reported halos and glare in postoperative 3 months, two of them needed to use spectacles to improve the intermediate visual acuity. Fifteen patients (94%) reported a satisfaction score of ≥3.5 out of 4.0, without any difficulty in daily activity. Thirteen patients (81%) did not need spectacles at all distances, while the other 3 patients (19%) used spectacles for near-distance related visual activity. Mean composite score of the VF-14 questionnaire was 95.00 ± 7.29 out of 100.

Conclusions

Trifocal IOL implantation after myopia excimer laser correction could restore good distance, intermediate visual acuity and acceptable near visual acuity, and provide accurate refractive outcomes as well as high spectacles independence rate.

Peer Review reports

Background

Corneal refractive laser surgery that began in the 1990s has been well developed and widely applied in ametropia correction for millions of patients. Over time, these patients eventually become presbyopic or cataractous and are more demanding for the freedom from glasses [1]. To that end, a further refractive procedure is required such as multifocal intraocular lens (IOL) implantation. With the continuous renewal and improvement of surgical equipment and implantation material, multifocal IOL implantation after cataract surgery has been increasingly applied in clinical practice and effectively restored visual acuity, thus becoming an alternative of refractive procedure [2,3,4,5,6,7]. Recently, some studies have shown that the multifocal IOL implantation could be safely and efficiently used for patients who had previously undergone corneal refractive laser surgery [8,9,10,11]. Obviously, the modern cataract surgery combining an intraocular lens implantation gradually becomes a refractive procedure rather than a treatment only for blindness. However, due to the difficulties in IOL power calculation and the potential side effects occurring postoperatively such as glare or other visual acuity problems, only few reports of the clinical observation of multifocal IOL implantation after previous corneal refractive laser surgery exist, and even less for the trifocal IOL implantation.

Currently, bifocal IOLs are used as the major multifocal IOLs with only near and far focus and hence provide good distance and near visual acuity and moderate intermediate vision. As a newly emerging product from IOL multifocality technological development, trifocal IOLs were designed to provide three useful focal distances (near, intermediate and far) and thus improve the intermediate vision without impairing distance and near visual acuity [12,13,14,15,16]. An increasing number of reported clinical observations have demonstrated the positive outcome after trifocal IOL implantation and recent systematic reviews also showed the advantages of trifocal IOLs in comparison with bifocal IOLs [17, 18]. Within this trend, trifocal IOLs would become a reliable alternative option for cataract patients with previous corneal refractive laser surgery in the foreseeable future. So far, there are few studies reporting the visual outcomes of trifocal IOL implantation after previous corneal refractive surgery. Wang et al. recently reported on a trifocal IOL implantation in eyes with nuclear cataract about 15 years after myopic LASIK surgery, which restored vision efficiently [19]. Chow and co-worker thereafter reported a case series of trifocal IOL implantation for post-myopic LASIK patients providing a good visual outcome at both near and distance vision [20]. To further confirm the clinical effect of trifocal IOL implantation after previous corneal refractive surgery, we herein present a retrospective case series of trifocal IOL (AT LISA tri 839MP) implantation in eyes with previous corneal refractive laser surgery for myopia. In this study, a multi-formula average method was performed for the IOLs power calculation to improve the accuracy. The visual and refractive outcomes were analyzed, and patient satisfaction and subjective quality of vision were also evaluated using VF-14 questionnaire and another short questionnaire concerning negative visual symptoms.

Methods

This retrospective case series included patients who had previously undergone LASIK or PRK for myopia and underwent femtosecond laser assisted phacoemulsification and trifocal IOL (AT LISA tri 839MP, Carl Zeiss Meditec AG, Jena, Germany) implantation in AIER Group’s Eye Hospitals (Beijing Aier-Intech Eye Hospital, Guangzhou Aier Eye Hospital, Chongqing Aier Eye Hospital, Wanzhou Aier Eye Hospital and Shenzhen Aier Eye Hospital) from January 2017 to May 2019. Ethics Committee approval by the Institutional Review Board of the Aier School of Ophthalmology of Central South University was obtained for the present study protocol that adhered to the tenets of the Declaration of Helsinki. Written informed consents were obtained from all the enrolled patients.

The inclusion criteria consisted of eyes (1) that had surgery indication for cataract surgery without any contraindications of ocular surgical therapy in the preoperative examination, (2) with corneal astigmatism ≤1.5 D and the angles of Kappa and Alpha both being < 0.3 mm, and (3) had no complications of posterior capsular rupture or zonular dialysis during the cataract surgery. The exclusion criteria included eyes that (1) had decentered ablation (decentration > 0.5 mm), corneal scar, retinoschisis, haze, myopic retinopathy, retinoschisis or retinal detachment after myopia excimer laser correction, (2) with corneal astigmatism ≥1.5 D or irregular astigmatism ≥0.3 μm, and (3) had inflammation, glaucoma or other diseases that might affect the multifocal IOL implantation.

Patient examinations

Enrolled patients all underwent preoperative ophthalmologic examinations including corrected distance visual acuity (CDVA), UDVA, manifest refraction, retinal visual acuity, intraocular pressure, ocular A and B-scan ultrasonography, non-contact specular microscope, optical coherence tomography (OCT) and ray tracing aberrometry. The retinal visual acuity was assessed with Lambda 100 retinometer (Heine, Germany). The axial length, keratometry and anterior chamber depth were measured using the LenStar LS900 (Haag Streit, Switzerland).

The postoperative measurements at 1-day, 1-month and 3-month included CDVA, UDVA, UIVA, UNVA, and the subjective manifest refractions (spherical equivalent) as well as their changes. Through-focus monocular logMAR acuity (defocus curve) was also measured. The spectacle independence rate, satisfaction, and visual symptoms were recorded at 3-month postoperatively with the Visual Function index 14 (VF-14) questionnaire, which provides an index of functional impairment in patients with cataract [21, 22], as well as another short questionnaire concerning negative visual symptoms. VF-14 was translated into Chinese [23] and based on 14 uncorrected vision–dependent daily activities, scoring each item with regard to the degree of difficulty as follows: no difficulty (4 score), a little difficulty (3 score), moderate difficulty (2 score), quite difficult (1 score), or impossible to perform the task (0 score). Items were not included in the scoring if patients could not perform the activity for reasons other than vision-related. Scores on all activities were averaged, and the mean score was then multiplied by 25. The resulting VF-14 score ranged from 0 (worst functional impairment) to 100 (no disability) [24]. The short questionnaire with regard to some negative visual symptoms commonly observed after cataract surgery, such as halo, glare, was recorded by the correspondent surgeon.

Surgical technique

All the surgeries were performed combining femtosecond laser-assisted phacoemulsification and intraocular lens implantation by experienced surgeons. For the eyes with corneal astigmatism between 0.75 D and 1.5 D (6 eyes), femtosecond laser-assisted corneal relaxing incision was performed for correction. Preoperatively, the surgeons used tropicamide to maintain pupil dilation intraoperatively. Under topical anaesthesia, capsulotomies (diameters were all set as 5.2 mm), lens fragmentation and corneal relaxing incisions were performed subsequently using the LenSx femtosecond laser (Alcon Laboratories, Inc., Fort Worth, Texas, USA). Phacoemulsification was then performed using standard ultrasound technique. In case of the patients with high myopia who underwent femtosecond laser surgery, both anterior and posterior capsules were thoroughly polished to reduce the risk of capsule contraction. The trifocal IOL (AT LISA tri 839MP) was implanted in the capsular bag using an injector. The residual ophthalmic viscosurgical device was removed, and the position of the lens was adjusted. All incisions were hydrated and the patients’ conjunctival sac was treated with dexamethasone-tobramycin ophthalmic ointment.

For lens power calculation, a multi-formula average method was performed, in which 4 formulas of Hagis-L [25], Barrett True K [26], Shammas No-History [27] and ray-tracing methods [28] setting the target refraction as postoperative emmetropia were used. The implanted IOL power was the average of the calculated results from all 4 formulas. For the first treated eye of patients who underwent bilateral implantation and the eyes with a large difference (> 1.0 D) in the IOL power calculations using the 4 formulas, a modified aphakic refraction technique was applied based on the reported aphakic refraction procedure by Dr. Mackool [29]. At first, the cataract removal was performed without IOL implantation. 1 Day later, manifest refraction examination was performed for the lens power calculation followed by the IOL insertion. All the two-staged-procedure surgeries were performed in the same fashion after obtaining patient’s consent. After 1 week, another eye surgery would be performed.

Postoperative treatment included one drop of tobramycin-dexamethasone eye drops every 2 h for 3 days, afterward four times per day until 2 weeks, and then three times per day for another 2 weeks; and one drop of levofloxacin eye drops four times every day for 1 week; pranoprofen and sodium hyaluronate eye drops were administered as appropriate.

Statistical analysis

Statistical analysis was performed using Microsoft Excel. Mean (± SD) was reported for continuous variables. Normal probability plots and Kolmogorov-Smirnov and Shapiro-Wilk tests were used to check the normality of data in SPSS software. Pre- and post-UDVA, pre- and post-CDVA outcomes were compared with the t test. Nonparametric tests were used to evaluate differences within groups. Differences were considered statistically significant when the P value was less than 0.05.

Results

This study comprised 21 eyes of 16 patients (five men, 31.3%). The demographics of the study population are summarized in Table 1. The mean patient age at the time of IOL implantation was 48.5 ± 8.9 years (range, 36 to 66 years). The mean time gab between the refractive surgery and cataract surgery is 13.2 ± 4.3 years. Eleven (68.7%) and five patients (31.3%) underwent unilateral and bilateral implantation respectively. No complications developed intraoperatively. No further laser enhancement was performed. The mean logMAR of UDVA and CDVA were 0.83 ± 0.48 (range, 0.22 to 1.70) and 0.37 ± 0.30 (range, 0.00 to 1.00), respectively. The mean axial length was 27.70 mm ± 2.20 (range, 25.13 to 33.00 mm). The mean preoperative spherical equivalent (SE) was − 5.49 D ± 5.75 (range, − 18.75 to + 1.37 D).

Table 1 Demographics of the patients before IOL implantation
Full size table

Refraction

After lens extraction and IOL implantation at 3-month, the mean SE was reduced to − 0.56 D ± 0.49. Figure 1a shows the change of mean SE at the three follow-up intervals (1-day, 1-month and 3-month). The histograms of the postoperative refractive accuracy are presented in Fig. 1b. Ten eyes (47.6%) were within ±0.50 D of the desired emmetropia and 19 eyes (90.5%) within ±1.0 D at postoperative 3 months. In contrast, only 3 eyes (14.3%) were within ±1.0 D preoperatively (Fig. 1c). Figure 1d shows the attempted versus achieved SE refraction. At 3-month follow-up, the overall rate of overcorrection was 0%, while the overall rate of undercorrection was 9.5% (2 eyes).

Fig. 1
figure 1

Refraction outcomes. a Changes of mean SE at the three follow-up intervals (1-day, 1-month and 3-month); b Histograms of the postoperative refractive accuracy; c Percentages of eyes within ±0.5 D and ± 1.0 D of emmetropia; d Spherical equivalent attempted versus achieved

Full size image

Visual acuity

The mean postoperative CDVA was 0.00 ± 0.05 logMAR, the mean postoperative UDVA was 0.10 ± 0.16 logMAR at the first day postoperatively (Table 2). All the surgery eyes (21 eyes, 100%) achieved postoperative CDVA ≥20/25, while the percentage for UDVA ≥20/25 was 76% (for the postoperative cumulative Snellen visual acuity, see Fig. 2a). Additionally, the mean postoperative UNVA, UIVA and UDVA at 3-month were 0.15 ± 0.11 logMAR, 0.10 ± 0.10 logMAR and 0.02 ± 0.07 logMAR respectively. All obtained monocular visual acuity data at the last visit are summarized in Table 2.

Table 2 Monocular visual acuity (logMAR)
Full size table
Fig. 2
figure 2

Visual outcomes. a Postoperative cumulative Snellen visual acuity; b Monocular distance-corrected defocus curve given in logMAR at 1-month postoperatively (N = 20)

Full size image

Defocus curve

Monocular defocus curve at 1-month (Fig. 2b, results of 20 eyes) showed best visual acuity (0.02 logMAR and 0.13 logMAR) with defocus of 0.00 D and − 3.00 D, simulating distances of 4 m and 33 cm. In the range between the peaks, the curve transited smoothly and reached the bottom as 0.14 logMAR at − 2.50 D. Besides the defocus of 1.50 D (with a visual acuity of 0.34 logMAR), all visual acuities tested at other defocus diopters were better than 0.23 logMAR, maintaining a functional range of visual acuity.

Questionnaires

Tables 3 and 4 summarized the results of the VF-14 and supplementary questionnaires. Three patients (19%) reported halos giving the least mean scores of all items in VF-14 questionnaire as 3.42, 3.50 and 3.64 respectively, two of them needed to use spectacles to improve the intermediate visual acuity. Thirteen patients (81%) did not need spectacles at all distances, while the other three patients (19%) reported the need to use spectacles only for the near-distance related visual activities such as reading books and doing handwork. Fifteen patients (94%) reported a satisfaction score of ≥3.5 out of 4.0, without any difficulty in daily activity.

Table 3 Three-month postoperative responses to visual function questionnaire (VF-14) itemsa
Full size table
Table 4 Results of the short questionnaire concerning negative visual symptoms in postoperative 3 months
Full size table

Discussion

Previous studies of eyes after corneal refractive laser surgery have focused primarily on monofocal IOLs [26, 30,31,32] and bifocal IOLs [8,9,10,11]. In our study, we present this retrospective case series of trifocal IOL (AT LISA tri839MP) implantation in patients who underwent a previous corneal refractive laser surgery for myopia. The AT LISA tri839MP used in our study is a monolithic diffractive trifocal intraocular lens which is made of collapsible hydrophilic acrylate (25%) with a hydrophobic surface. Its optical zone has a diameter of 6.0 mm, a total diameter of 11.0 mm, and a four-turn intraocular lens with a zero angle. The intraocular lens combines a bifocal diffraction range from 4.34 to 6.00 mm, and a trifocal diffraction range (over 4.34 mm) on the front surface of the lens, which is achieved based on the asymmetrical light split, that is 30, 20, and 50% of the incoming light is split at near focus, intermediate focus, and distant focus respectively. It was developed to overcome the photic phenomena and the poor level of intermediate vision of traditional multifocal IOLs [33] and has already been demonstrated to have good outcomes of visual acuity at near, intermediate and far distance and high postoperative satisfaction [34]. Patients were extensively counselled regarding the possible side effects of the treatment such as night glare, halos and decreased contrast sensitivity, even the possibility of deteriorated visual quality after a refractive corneal laser procedure. The final decision was made based on their wishes to restore vision and hence becoming independent of spectacles.

Intraocular lens implantation in eyes with previous corneal refractive laser surgery is full of challenges due to the difficulty in IOL power calculation [30, 35, 36]. To date, some reported IOL power calculation methods have been used for IOL implantation in eyes with previous corneal refractive laser surgery providing relatively accurate outcomes [31, 37, 38]. However, obvious hyperopia is often observed postoperatively [39, 40]. For the lens power calculation in the present study, a multi-formula average method was applied which has been described and proven to be accurate in our previous study [41]. Additionally, corneal edema and intraocular pressure (IOP) changes could also affect the intraoperative calculation of lens power. A modified aphakic refraction technique was used in our study for the first operative eyes of patients who underwent bilateral implantation and the eyes with large difference (> 1.0 D) in the IOL calculated results from multi-formulas. The time gap between the cataract removal and manifest aphakic refraction was extended from 30 min (Dr. Mackool’s procedure [29]) to 1 day. This extension has been demonstrated to increase the stabilization of refraction in our previous observation, and hence reduce the error giving a more accurate calculation result. Both these improvements were made based on the previous investigation and to pursuit accuracy in IOL power calculation.

In the refraction outcome, the mean postoperative SE was reduced to − 0.56 D ± 0.49 while Chow’s study reported a − 0.92 D ± 0.76 with a significant myopic shift [20]. In addition, 10 eyes (47.6%) were within ±0.50 D of the desired emmetropia and 19 eyes (90.5%) within ±1.0 D at postoperative 3 months in our study. All our cases were targeted for emmetropia, and the results were similar to Vrijman’s study with a lower percentage of eyes with ±0.50 D. This is because most of the patients included were preoperatively high myopia with either less spherical equivalent (9 eyes, 43%, with < − 6.00 D) or longer axial length (16 eyes, 76%, with > 26.00 mm). It is consistent with Vrijman’s finding that results were less predictable in eyes with myopia greater than 6.0 D [10].

The results of vision outcomes show a statically significant improvement after surgery. The mean postoperative CDVA and UDVA was 0.00 ± 0.05 and 0.10 ± 0.16 (logMAR), respectively. Both these two outcomes are significantly better than preoperative outcomes (Table 2, P < 0.001). The mean value of postoperative CDVA agrees with the result of Chang and co-workers (20/19, Snellen Vision) by converting into Snellen Vision [11]. To accurately evaluate the visual outcomes of trifocal IOLs after previous corneal refractive surgery, the monocular UDVA, UIVA and UNVA were recorded at last follow up in our study, and the mean values (logMAR) were 0.02 ± 0.07, 0.10 ± 0.10 and 0.15 ± 0.11 respectively. However, among the few reports using multifocal IOL implantation, only Chang’s study recorded the same visual outcomes wherein the mean UIVA was 0.22 ± 0.15 (logMAR) as higher than the value we observed. These results indicated that the trifocal IOL implantation for the cataract patients who previously had underwent myopia excimer laser correction, could restore good distance, intermediate visual acuity and acceptable near visual acuity.

As an important indicator for the vision over the entire range, defocus curve was also recorded in this study. In 2015, Jonker et al. compared the defocus curves after trifocal IOL implantation with that after bifocal IOL implantation in cataract patients [13]. In their comparison, the defocus curves of the trifocal IOL group showed a more continuous performance at the intermediate range under photopic and mesopic conditions. In the defocus curve of our study, the curve transited smoothly in the range between the peaks with defocus of 0.00 D and − 3.00 D and reached the bottom as 0.14 logMAR at − 2.50 D. Besides the defocus of 1.50 D (with a mean visual acuity of 0.34 logMAR), all visual acuities tested at other defocus diopters were better than 0.23 logMAR, maintaining a functional range of visual acuity. These results further demonstrate the good and wide range visual outcomes of trifocal IOL implantation after previous corneal refractive laser surgery for myopia.

In terms of the questionnaires survey, three patients (19%) reported halos and glare in postoperative 3 months, while no patient reported flare. Two of these three patients needed to use spectacles to read small print or a newspaper or book or to do some handwork. Looking back on the preoperative parameters of the two patients, both of their surgery eyes were with high myopia (preoperative spherical equivalents are − 7.60 and − 12.37 respectively). It seems that the capsule of high myopic patients is larger, and the stability of intraocular lenses is slightly worse compared to normal patients. The position and functional deviation of intraocular lens might lead to bad visual symptoms such as halos. In the other hand, the preoperative symptoms of halos or glare, and the status of the fellow untreated eye from patients who was performed unilateral surgery, might affect the postoperative visual outcomes and interfere with the clinical analysis of the efficiency of trifocal IOL implantation. Unfortunately, all the information had not been recorded preoperatively. Nevertheless, the total spectacles independence rate is 81% (13 patients), and those patients without halos or glare all have scores better than 3.67. Overall, the questionnaires survey showed good quality of life postoperatively in the current study.

The limitation of this study was the small sample size. Undoubtedly, a larger sample size would be more helpful to shed light onto the efficiency of trifocal IOL implantation after previous corneal refractive laser surgery for myopia. However, due to the uncertain side effects of multifocal IOL implantation after previous corneal surgery, the number of patients who balanced the side effects by their demands for becoming independent of spectacles are rare. Nevertheless, the trifocal IOL implantation should be a good option to restore wide range visual acuity well for the cataract patients with previous corneal refractive laser surgery for myopia.

Conclusions

In conclusion, the trifocal intraocular lens can safely provide a full range of adequate vision and accurate refractive outcomes for cataract patients after myopic excimer laser correction. The high spectacle independence rate affords the patients a high satisfaction. Only few side effects such as halos and glare were observed and are possibly caused by extremely high myopia in few of the patients.

Availability of data and materials

The analytic data used to support the findings of this study are included within the article. Other original data used to support the findings of this study are available from the corresponding author upon request.

Abbreviations

IOL:

Intraocular lens

UDVA:

Uncorrected distance visual acuity

UIVA:

Uncorrected intermediate visual acuity

UNVA:

Uncorrected near visual acuity

LASIK:

Laser in situ keratomileusis

PRK:

Photorefractive keratectomy

SE:

Spherical equivalent

D:

Diopter

SD:

Standard deviation

logMAR:

Logarithm of the minimal angle of resolution

CDVA:

Corrected distance visual acuity

OCT:

Optical coherence tomography

IOP:

Intraocular pressure

References

  1. Iijima K, Kamiya K, Shimizu K, Igarashi A, Komatsu M. Demographics of patients having cataract surgery after laser in situ keratomileusis. J Cataract Refract Surg. 2015;41(2):334–8.

    PubMed  Google Scholar 

  2. Yoshino M, Bissen-Miyajima H, Minami K, Taira Y. Five-year postoperative outcomes of apodized diffractive multifocal intraocular lens implantation. Jpn J Ophthalmol. 2013;57:510–3.

    Google Scholar 

  3. van der Linden JW, van der Meulen IJ, Mourits MP, Lapid-Gortzak R. Comparison of a hydrophilic and a hydrophobic apodized diffractive multifocal intraocular lens. Int Ophthalmol. 2013;33(5):493–500.

    PubMed  PubMed Central  Google Scholar 

  4. de Vries NE, Webers CA, Montes-Mico R, Tahzib NG, Cheng YY, de Brabander J, Hendrikse F, Nuijts RM. Long-term follow-up of a multifocal apodized diffractive intraocular lens after cataract surgery. J Cataract Refract Surg. 2008;34(9):1476–82.

    PubMed  Google Scholar 

  5. Rosen E, Alio JL, Dick HB, Dell S, Slade S. Efficacy and safety of multifocal intraocular lenses following cataract and refractive lens exchange: Metaanalysis of peer-reviewed publications. J Cataract Refract Surg. 2016;42(2):310–28.

    PubMed  Google Scholar 

  6. Liu X, Xie L, Huang Y. Comparison of the visual performance after implantation of bifocal and trifocal intraocular lenses having an identical platform. J Refract Surg. 2018;34(4):273–80.

    PubMed  Google Scholar 

  7. Li S, Jie Y. Cataract surgery and lens implantation. Curr Opin Ophthalmol. 2019;30(1):39–43.

    PubMed  Google Scholar 

  8. Fernandez-Vega L, Madrid-Costa D, Alfonso JF, Montes-Mico R, Poo-Lopez A. Optical and visual performance of diffractive intraocular lens implantation after myopic laser in situ keratomileusis. J Cataract Refract Surg. 2009;35(5):825–32.

    PubMed  Google Scholar 

  9. Muftuoglu O, Dao L, Mootha VV, Verity SM, Bowman RW, Cavanagh HD, McCulley JP. Apodized diffractive intraocular lens implantation after laser in situ keratomileusis with or without subsequent excimer laser enhancement. J Cataract Refract Surg. 2010;36(11):1815–21.

    PubMed  Google Scholar 

  10. Vrijman V, van der Linden JW, van der Meulen IJE, Mourits MP, Lapid-Gortzak R. Multifocal intraocular lens implantation after previous corneal refractive laser surgery for myopia. J Cataract Refract Surg. 2017;43(7):909–14.

    PubMed  Google Scholar 

  11. Chang JS, Ng JC, Chan VK, Law AK. Visual outcomes, quality of vision, and quality of life of diffractive multifocal intraocular lens implantation after myopic laser in situ keratomileusis: a prospective, observational case series. J Ophthalmol. 2017;2017:6459504.

    PubMed  PubMed Central  Google Scholar 

  12. Vryghem JC, Heireman S. Visual performance after the implantation of a new trifocal intraocular lens. Clin Ophthalmol. 2013;7:1957–65.

    PubMed  PubMed Central  Google Scholar 

  13. Jonker SM, Bauer NJ, Makhotkina NY, Berendschot TT, van den Biggelaar FJ, Nuijts RM. Comparison of a trifocal intraocular lens with a +3.0 D bifocal IOL: results of a prospective randomized clinical trial. J Cataract Refract Surg. 2015;41(8):1631–40.

    PubMed  Google Scholar 

  14. Mojzis P, Kukuckova L, Majerova K, Liehneova K, Pinero DP. Comparative analysis of the visual performance after cataract surgery with implantation of a bifocal or trifocal diffractive IOL. J Refract Surg. 2014;30(10):666–72.

    PubMed  Google Scholar 

  15. Plaza-Puche AB, Alio JL. Analysis of defocus curves of different modern multifocal intraocular lenses. Eur J Ophthalmol. 2016;26(5):412–7.

    PubMed  Google Scholar 

  16. Plaza-Puche AB, Alio JL, Sala E, Mojzis P. Impact of low mesopic contrast sensitivity outcomes in different types of modern multifocal intraocular lenses. Eur J Ophthalmol. 2016;26(6):612–7.

    PubMed  Google Scholar 

  17. Shen Z, Lin Y, Zhu Y, Liu X, Yan J, Yao K. Clinical comparison of patient outcomes following implantation of trifocal or bifocal intraocular lenses: a systematic review and meta-analysis. Sci Rep. 2017;7:45337.

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Xu ZQ, Cao DM, Chen X, Wu S, Wang X, Wu Q. Comparison of clinical performance between trifocal and bifocal intraocular lenses: a meta-analysis. PLoS One. 2017;12(10):e0186522.

    PubMed  PubMed Central  Google Scholar 

  19. Wang W, Ni S, Li X, Chen X, Zhu Y, Xu W. Femtosecond laser-assisted cataract surgery with implantation of a diffractive trifocal intraocular lens after laser in situ keratomileusis: a case report. BMC Ophthalmol. 2018;18(1):160.

    PubMed  PubMed Central  Google Scholar 

  20. Chow SSW, Chan TCY, Ng ALK, Kwok AKH. Outcomes of presbyopia-correcting intraocular lenses after laser in situ keratomileusis. Int Ophthalmol. 2019;39(5):1199–204.

    PubMed  Google Scholar 

  21. Steinberg EP, Tielsch JM, Schein OD, Javitt JC, Sharkey P, Cassard SD, Legro MW, Diener-West M, Bass EB, Damiano AM, et al. The VF-14. An index of functional impairment in patients with cataract. Arch Ophthalmol. 1994;112(5):630–8.

    CAS  PubMed  Google Scholar 

  22. Alonso J, Espallargues M, Andersen TF, Cassard SD, Dunn E, Bernth-Petersen P, Norregaard JC, Black C, Steinberg EP, Anderson GF. International applicability of the VF-14. An index of visual function in patients with cataracts. Ophthalmology. 1997;104(5):799–807.

    CAS  PubMed  Google Scholar 

  23. Khadka J, Huang J, Mollazadegan K, Gao R, Chen H, Zhang S, Wang Q, Pesudovs K. Translation, cultural adaptation, and Rasch analysis of the visual function (VF-14) questionnaire. Invest Ophthalmol Vis Sci. 2014;55(7):4413–20.

    PubMed  Google Scholar 

  24. Song X, Liu X, Wang W, Zhu Y, Qin Z, Lyu D, Shentu X, Xv W, Chen P, Ke Y. Visual outcome and optical quality after implantation of zonal refractive multifocal and extended-range-of-vision IOLs: a prospective comparison. J Cataract Refract Surg. 2020;46(4):540–8.

    PubMed  Google Scholar 

  25. Haigis W. Intraocular lens calculation after refractive surgery for myopia: Haigis-L formula. J Cataract Refract Surg. 2008;34(10):1658–63.

    PubMed  Google Scholar 

  26. Abulafia A, Hill WE, Koch DD, Wang L, Barrett GD. Accuracy of the Barrett true-K formula for intraocular lens power prediction after laser in situ keratomileusis or photorefractive keratectomy for myopia. J Cataract Refract Surg. 2016;42(3):363–9.

    PubMed  Google Scholar 

  27. Shammas HJ, Shammas MC. No-history method of intraocular lens power calculation for cataract surgery after myopic laser in situ keratomileusis. J Cataract Refract Surg. 2007;33(1):31–6.

    PubMed  Google Scholar 

  28. Savini G, Bedei A, Barboni P, Ducoli P, Hoffer KJ. Intraocular lens power calculation by ray-tracing after myopic excimer laser surgery. Am J Ophthalmol. 2014;157(1):150–3.

    PubMed  Google Scholar 

  29. Mackool RJ, Ko W, Mackool R. Intraocular lens power calculation after laser in situ keratomileusis: Aphakic refraction technique. J Cataract Refract Surg. 2006;32(3):435–7.

    PubMed  Google Scholar 

  30. Wang L, Hill WE, Koch DD. Evaluation of intraocular lens power prediction methods using the American Society of Cataract and Refractive Surgeons Post-Keratorefractive Intraocular Lens Power Calculator. J Cataract Refract Surg. 2010;36(9):1466–73.

    PubMed  Google Scholar 

  31. Wang L, Tang M, Huang D, Weikert MP, Koch DD. Comparison of newer intraocular lens power calculation methods for eyes after corneal refractive surgery. Ophthalmology. 2015;122(12):2443–9.

    PubMed  PubMed Central  Google Scholar 

  32. McCarthy M, Gavanski GM, Paton KE, Holland SP. Intraocular lens power calculations after myopic laser refractive surgery: a comparison of methods in 173 eyes. Ophthalmology. 2011;118(5):940–4.

    PubMed  Google Scholar 

  33. Mojzis P, Majerova K, Hrckova L, Pinero DP. Implantation of a diffractive trifocal intraocular lens: one-year follow-up. J Cataract Refract Surg. 2015;41(8):1623–30.

    PubMed  Google Scholar 

  34. Kohnen T, Titke C, Bohm M. Trifocal intraocular lens implantation to treat visual demands in various distances following lens removal. Am J Ophthalmol. 2016;161:71–7.

    PubMed  Google Scholar 

  35. Seitz B, Langenbucher A, Nguyen NX, Kus MM, Kuchle M. Underestimation of intraocular lens power for cataract surgery after myopic photorefractive keratectomy. Ophthalmology. 1999;106(4):693–702.

    CAS  PubMed  Google Scholar 

  36. Chan TC, Liu D, Yu M, Jhanji V. Longitudinal evaluation of posterior corneal elevation after laser refractive surgery using swept-source optical coherence tomography. Ophthalmology. 2015;122(4):687–92.

    PubMed  Google Scholar 

  37. Chen X, Yuan F, Wu L. Metaanalysis of intraocular lens power calculation after laser refractive surgery in myopic eyes. J Cataract Refract Surg. 2016;42(1):163–70.

    PubMed  Google Scholar 

  38. Savini G, Hoffer KJ. Intraocular lens power calculation in eyes with previous corneal refractive surgery. Eye Vis (Lond). 2018;5:18.

    Google Scholar 

  39. Saiki M, Negishi K, Kato N, Torii H, Dogru M, Tsubota K. Ray tracing software for intraocular lens power calculation after corneal excimer laser surgery. Jpn J Ophthalmol. 2014;58(3):276–81.

    PubMed  Google Scholar 

  40. Hoffer KJ. Intraocular lens power calculation after previous laser refractive surgery. J Cataract Refract Surg. 2009;35(4):759–65.

    PubMed  Google Scholar 

  41. Yu ZX, Li SW, Huo DM, Xu M, Shi S, Liu C, Zhao R. Evaluation of the accuracy of Sirius ray-tracing method for IOL power calculation in post-corneal-refractive-surgery eyes. Ophthalmol CHN. 2019;28(2):98–103.

    Google Scholar 

Download references

Acknowledgements

Not Applicable.

Funding

This study was supported by Aier Eye Hospital Group Scientific Research Project Grant [no. AF152D01], Changsha, China. The funding bodies had no role in the design of the study and collection, analysis, and interpretation and data and in the writing of the manuscript.

Author information

Author notes

  1. Qiu-Mei Li and Feng Wang contributed equally to this work.

Authors and Affiliations

  1. Beijing Aier-Intech Eye Hospital, Beijing, 100021, China

    Qiu-Mei Li & Shao-Wei Li

  2. Department of Ophthalmology, Aier School of Ophthalmology, Central South University, Changsha, 410083, China

    Feng Wang & Shao-Wei Li

  3. Department of Ophthalmology, Justus-Liebig-University, 35385, Giessen, Germany

    Feng Wang & Knut Stieger

  4. Guangzhou Aier Eye Hospital, Guangzhou, 510260, China

    Zhe-Ming Wu

  5. Chongqing Aier Eye Hospital, Chongqing, 400020, China

    Zhen Liu

  6. Wanzhou Aier Eye Hospital, Chongqing, 404000, China

    Chuan Zhan

  7. Shenzhen Aier Eye Hospital, Shenzhen, 518005, China

    Bing-Heng Chen & Jing Sima

Authors
  1. Qiu-Mei Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Feng Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhe-Ming Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zhen Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Chuan Zhan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Bing-Heng Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jing Sima
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Knut Stieger
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Shao-Wei Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Both QML and FW contributed equally to this work. SWL and KS conceived of and designed this study. SWL, ZMW, ZL, CZ, BHC, JS performed the surgeries and contributed to the data acquisition. QML performed the patient follow-up and data collection. QML and FW conducted independently the data analysis and rechecking. FW drafted the initial manuscript. FW, SWL and KS revised the manuscript critically for important intellectual content. This manuscript has been read and approved by all the authors and each author believes that the manuscript represents honest work.

Corresponding authors

Correspondence to Knut Stieger or Shao-Wei Li.

Ethics declarations

Ethics approval and consent to participate

Ethics Committee approval by the Institutional Review Board of the Aier School of Ophthalmology of Central South University was obtained for the present study protocol that adhered to the tenets of the Declaration of Helsinki. Written informed consents were obtained from all the enrolled patients.

Consent for publication

Not Applicable.

Competing interests

The authors declare that they have no conflicts of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, QM., Wang, F., Wu, ZM. et al. Trifocal diffractive intraocular lens implantation in patients after previous corneal refractive laser surgery for myopia. BMC Ophthalmol 20, 293 (2020). https://doi.org/10.1186/s12886-020-01556-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1186/s12886-020-01556-0

Keywords

BMC Ophthalmology

ISSN: 1471-2415

Contact us