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  1. Ptosis incidence following cataract surgery is reduced with a recently developed phacoemulsification technique using a small incision. However, it remains uncertain whether an upper transconjunctival sclerocor...

    Authors: Rikiya Tamaki, Masahiko Gosho, Kyoichi Mizumoto, Nahoko Kato and Masahiro Zako
    Citation: BMC Ophthalmology 2016 16:95
    Content type: Research article Published on:

  3. Commonly used vision-targeted health-related quality of life questionnaires almost exclusively focus items on vision under daytime conditions. Older adults even when in good eye health frequently report experi...

    Authors: Cynthia Owsley and Gerald McGwin Jr
    Citation: BMC Ophthalmology 2016 16:92
    Content type: Research article Published on:

  4. Report of three patients with pseudophakic angle-closure from a Soemmering ring. Three mechanisms of the Soemmering ring induced pseudophakic angle-closure in three patients were demonstrated by meticulous ant...

    Authors: Yanin Suwan, Bayasgalan Purevdorj, Chaiwat Teekhasaenee, Wasu Supakontanasan and Pornchai Simaroj
    Citation: BMC Ophthalmology 2016 16:91
    Content type: Case report Published on:

  5. Mutations in candidate genes that encode for a ligand (NDP) and receptor complex (FZD4, LRP5 and TSPAN12) in the Norrin β-catenin signaling pathway are involved in the pathogenesis of familial exudative vitreoret...

    Authors: Ganeswara Rao Musada, Hameed Syed, Subhadra Jalali, Subhabrata Chakrabarti and Inderjeet Kaur
    Citation: BMC Ophthalmology 2016 16:90
    Content type: Research article Published on:

  7. Computer based surgical training is believed to be capable of providing a controlled virtual environment for medical professionals to conduct standardized training or new experimental procedures on virtual hum...

    Authors: Chee Kiang Lam, Kenneth Sundaraj, Mohd Nazri Sulaiman and Fazilawati A. Qamarruddin
    Citation: BMC Ophthalmology 2016 16:88
    Content type: Research article Published on:

  8. To evaluate the anatomical and visual outcomes by par plana vitrectomy with or without internal limiting membrane (ILM) peeling in highly myopic eyes with macular hole retinal detachment (MHRD).

    Authors: Xinxiao Gao, Jia Guo, Xin Meng, Jun Wang, Xiaoyan Peng and Yasushi Ikuno
    Citation: BMC Ophthalmology 2016 16:87
    Content type: Research article Published on:

  9. Capsular block syndrome is an uncommon complication that occurs after cataract surgery. It is characterized by capsular distension, anterior intraocular lens displacement, anterior chamber shallowing, and unex...

    Authors: Joong Sik Koh, Young Bin Song, Won Ryang Wee and Young Keun Han
    Citation: BMC Ophthalmology 2016 16:86
    Content type: Case report Published on:

  13. Postoperative optic opacification of hydrophilic acrylic intraocular lenses (IOLs) is an uncommon complication leading to IOL explantation. In the past decade, several studies reported that the granular deposi...

    Authors: Dan Cao, Hongyang Zhang, Cheng Yang and Liang Zhang
    Citation: BMC Ophthalmology 2016 16:82
    Content type: Case report Published on:

  14. Cytomegalovirus (CMV) is the most common congenital infection, and chorioretinitis is the most common ophthalmic manifestation of congenital CMV infection. We experienced a unique case of CMV retinopathy showi...

    Authors: Mizuki Tagami, Shigeru Honda, Ichiro Morioka, Kazumoto Iijima, Hideto Yamada and Makoto Nakamura
    Citation: BMC Ophthalmology 2016 16:81
    Content type: Case report Published on:

  15. Immune responses play a key role in the pathogenesis and progression of polypoidal choroidal vasculopath (PCV) and age-related macular degeneration (AMD). In this study, we determined the Th cell-associated im...

    Authors: Ying Yu, Xiang Rong Ren, Feng Wen, Hui Chen and Shao Bo Su
    Citation: BMC Ophthalmology 2016 16:80
    Content type: Research article Published on:

  16. Cross-sectional survey of ocular biometry and visual function in healthy eyes across the life span of a German population aged 20 to 69 years (n = 218). Subject number in percent per age category reflected the pe...

    Authors: Maria Teresa Zocher, Jos J. Rozema, Nicole Oertel, Jens Dawczynski, Peter Wiedemann and Franziska G. Rauscher
    Citation: BMC Ophthalmology 2016 16:79
    Content type: Research article Published on:

  17. The glaucoma-specific blindness prevalence in Nigeria (0.7 %, 95 % CI 0.6–0.9 %) among those aged ≥40 years is one of the highest ever reported. This study determined the risk factors for open-angle glaucoma (...

    Authors: Fatima Kyari, Mohammed M. Abdull, Richard Wormald, Jennifer R. Evans, Winifred Nolan, Gudlavelleti V. S. Murthy and Clare E. Gilbert
    Citation: BMC Ophthalmology 2016 16:78
    Content type: Research article Published on:

  20. To assess the neuroprotective effect of etanercept (Enbrel®) which is a commercialized Tumor necrosis factor-α (TNF-α) inhibitor on axonal injury in an animal model of acute ischemia.

    Authors: Hyoung Won Bae, Naeun Lee, Gong Je Seong, Seungsoo Rho, Samin Hong and Chan Yun Kim
    Citation: BMC Ophthalmology 2016 16:75
    Content type: Research article Published on:

  21. Extracellular matrix remodelling regulated by matrix-metalloproteinase (MMP) inducer (CD147) is a crucial process during tumor cell invasion and regulation of blood supply. In this study, we evaluated the corr...

    Authors: Julia Lüke, Vlatka Vukoja, Tim Brandenbusch, Khaled Nassar, Jens Martin Rohrbach, Salvatore Grisanti, Matthias Lüke and Aysegül Tura
    Citation: BMC Ophthalmology 2016 16:74
    Content type: Research article Published on:

  23. The PlusOptix photoscreeners (PlusOptix GmbH, Nuremberg, Germany) is used in many vision screening programs. The purpose of the present study was to further explore the accuracy of the PlusOptix A09 photoscree...

    Authors: Arnaud Payerols, Claudie Eliaou, Véronique Trezeguet, Max Villain and Vincent Daien
    Citation: BMC Ophthalmology 2016 16:72
    Content type: Research article Published on:

  25. The aim of this study was to assess the intraocular pressure and ocular biometric parameters in migraine patients during acute migraine attacks and compare them with painless period and healthy controls using ...

    Authors: Yaran Koban, Hatice Kose Ozlece, Gorkem Bilgin, Mustafa Koc, Halil Huseyin Cagatay, Emre I. Durgunlu and Ayse Burcu
    Citation: BMC Ophthalmology 2016 16:70
    Content type: Research article Published on:

  26. The aim of this study was to investigate the effect of intravitreal anti-vascular endothothelial growth factor (VEGF) injection on intraocular pressure (IOP) and mean ocular perfusion pressure (MOPP).

    Authors: Jong Wook Lee, Hoon Park, Jeong Han Choi, Hyun Joo Lee, Sang Woong Moon, Ja Heon Kang and Young Gyun Kim
    Citation: BMC Ophthalmology 2016 16:69
    Content type: Research article Published on:

  30. Researches have shown anti-vascular endothelial growth factor (VEGF) agent is effective in treating neovascular eye diseases. The purpose of this study is to evaluate the efficacy and safety of intravitreal ra...

    Authors: Lan Liu, Yongfeng Xu, Zhu Huang and Xiaoyu Wang
    Citation: BMC Ophthalmology 2016 16:65
    Content type: Research article Published on:

  31. We describe two cases of recurrent acute angle-closure attack in patients with plateau iris syndrome after cataract extraction. Argon laser peripheral iridoplasty and cataract extraction have been used to redu...

    Authors: Bonnie Nga Kwan Choy, Jonathan Cheuk Hung Chan, Carol Pui Yang Chien and Jimmy Shiu Ming Lai
    Citation: BMC Ophthalmology 2016 16:64
    Content type: Case report Published on:

  34. Although intravitreal injection of bevacizumab (IVB) is effective for macular edema in patients with branch retinal vein occlusion (BRVO), the changes of retinal hemodynamics remain unclear. We investigated re...

    Authors: Hidetaka Noma, Kanako Yasuda, Terumi Minezaki, Sho Watarai and Masahiko Shimura
    Citation: BMC Ophthalmology 2016 16:61
    Content type: Research article Published on:

  35. The purpose of this study was to evaluate the extension and traction effects of posterior vitreous detachment (PVD) complicated with retinal tears using spectral domain optical coherence tomography (OCT) and B...

    Authors: Solmaz Abdolrahimzadeh, Domenica Carmen Piraino, Vittorio Scavella, Barmak Abdolrahimzadeh, Filippo Cruciani, Magda Gharbiya and Santi Maria Recupero
    Citation: BMC Ophthalmology 2016 16:60
    Content type: Research article Published on:

  36. The aim of this work is to refine understanding of anatomical and functional alterations in eyes with Intermediate Uveitis (IU), their natural history in mild cases not necessitating treatment and their respon...

    Authors: Bruno Simonazzi, Konstantinos Balaskas and Yan Guex-Crosier
    Citation: BMC Ophthalmology 2016 16:59
    Content type: Research article Published on:

  37. Aphakic glaucoma is a common complication after congenital cataract extraction, especially in those who have surgery during infancy. This case report describes a case of bilateral pupillary block glaucoma diag...

    Authors: Xiang-Jia Zhu, Ke-Ke Zhang, Wen-Wen He, Xing-Huai Sun, Fan-Rong Meng and Yi Lu
    Citation: BMC Ophthalmology 2016 16:58
    Content type: Case report Published on:

  38. Angiogenin (ANG), a component of tears, is involved in the innate immune system and is related with inflammatory disease. We investigated whether ANG has an immune modulatory function in human corneal fibrobla...

    Authors: Seung Hoon Lee, Kyoung Woo Kim, Kwangsic Joo and Jae Chan Kim
    Citation: BMC Ophthalmology 2016 16:57
    Content type: Research article Published on:

  39. Utility of visual impairment caused by amblyopia is important for the cost-effectiveness of screening for amblyopia (lazy eye, prevalence 3–3.5 %). We previously measured decrease of utility in 35-year-old per...

    Authors: Elizabeth S. van de Graaf, Dominiek D. G. Despriet, Caroline C. W. Klaver and Huibert J. Simonsz
    Citation: BMC Ophthalmology 2016 16:56
    Content type: Research article Published on:

  41. Conjunctival myxomas are rare, benign, connective tissue tumours that classically present as slow-growing, painless, well-circumscribed masses (Arch Ophthalmol 124:735-8, 2006; Case Rep Ophthalmol 3:145-50, 20...

    Authors: Neharika Sharma, Stephen O’Hagan and Gael Phillips
    Citation: BMC Ophthalmology 2016 16:54
    Content type: Case report Published on:

  42. Diagnostic tests for dry eye disease (DED), including ocular surface disease index (OSDI), tear breakup time (TBUT), corneal fluorescein staining, and lissamine staining, have great deal of variability. We inv...

    Authors: Kenji Fujitani, Neha Gadaria, Kyu-In Lee, Brendan Barry and Penny Asbell
    Citation: BMC Ophthalmology 2016 16:53
    Content type: Research article Published on:

  43. A position paper based on the collective experiences of Argus II Retinal Prosthesis System investigators to review strategies to optimize outcomes in patients with retinitis pigmentosa undergoing retinal prost...

    Authors: Devon H. Ghodasra, Adrienne Chen, J. Fernando Arevalo, David G. Birch, Kari Branham, Brian Coley, Gislin Dagnelie, Eugene de Juan, Robert G. Devenyi, Jessy D. Dorn, Andy Fisher, Duane R. Geruschat, Ninel Z. Gregori, Robert J. Greenberg, Paul Hahn, Allen C. Ho…
    Citation: BMC Ophthalmology 2016 16:52
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Ophthalmology 2016 16:129

  44. We explore and compare the advantages and disadvantages of different operating methods for a peripheral iridectomy (PI) for phakic posterior chamber implantable contact lens (ICL) implantation in patients with...

    Authors: Yan Wu, Fei Han, Yan Quan, Wei Jiang, Hengdi Zhang and Tao Luo
    Citation: BMC Ophthalmology 2016 16:51
    Content type: Research article Published on:

  45. Several techniques for fixation of the posterior chamber intraocular lens (IOL) have been developed. We evaluate long-term functional outcomes and safety of posterior chamber IOL implantation using Hoffman scl...

    Authors: Dariusz Haszcz, Katarzyna Nowomiejska, Agnieszka Oleszczuk, Cesare Forlini, Matteo Forlini, Joanna Moneta-Wielgos, Ryszard Maciejewski, Katarzyna Michalska-Malecka, Anselm G. Jünemann and Robert Rejdak
    Citation: BMC Ophthalmology 2016 16:50
    Content type: Research article Published on:

  46. This study evaluated the anterior ocular segment in a pseudophakic eye with angle closure due to a plateau-like iris associated with Soemmering’s ring, using ultrasound biomicroscopy (UBM) and anterior segment...

    Authors: Fumika Kitamura, Toshihiro Inoue, Utako Kuroda and Hidenobu Tanihara
    Citation: BMC Ophthalmology 2016 16:49
    Content type: Case report Published on:

  47. Excessive weight is a well-known risk factor for microvascular diseases. Changes in thickness in a vascular tissue, such as the choroid, can be useful to evaluate the effect of obesity on the microvascular sys...

    Authors: Erhan Yumusak, Kemal Ornek, Senay Arıkan Durmaz, Aydin Cifci, Hatice Ayhan Guler and Zehra Bacanli
    Citation: BMC Ophthalmology 2016 16:48
    Content type: Research article Published on:

  48. Ocular biometry is important for preoperative assessment in cataract and anterior segment surgery. The purpose of this study was to investigate normative ocular biometric parameters and their associations in a...

    Authors: Hui Chen, Haotian Lin, Zhuoling Lin, Jingjing Chen and Weirong Chen
    Citation: BMC Ophthalmology 2016 16:47
    Content type: Research article Published on:

  49. Iris plays important roles in ocular physiology and disease pathogenesis. Currently it is technically challenging to noninvasively examine the human iris ultrastructure in vivo. The purpose of the current stud...

    Authors: Ming Li, Hongbo Cheng, Ping Guo, Chun Zhang, Song Tang and Shusheng Wang
    Citation: BMC Ophthalmology 2016 16:46
    Content type: Research article Published on:

  50. To determine the stereoacuity threshold with a 3D laptop equipped with 3D shutter glasses, and to evaluate the effect of different shape and size of test symbols and different type of disparities to stereoacuity.

    Authors: Huang Wu, Han Jin, Ying Sun, Yang Wang, Min Ge, Yang Chen and Yunfeng Chi
    Citation: BMC Ophthalmology 2016 16:45
    Content type: Research article Published on:
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