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  1. Discovery of sessile mode of microbial existence (Biofilm state) focussed much interest, during the recent years, on the study of biofilms in many recurring and chronic infections. However, the exact role of m...

    Authors: Niranjan Nayak, Gita Satpathy, Sujata Prasad, Alok Thakar, Mahesh Chandra and TC Nag
    Citation: BMC Ophthalmology 2016 16:165
  2. Vernal keratoconjunctivitis (VKC) is a common cause of ocular morbidity in children in warm dry climates such as Sub–Saharan Africa and accounts for about 3 % of serious ophthalmic cases in tropical countries....

    Authors: Dereje Hayilu, Kbrom Legesse, Natinael Lakachew and Mulusew Asferaw
    Citation: BMC Ophthalmology 2016 16:167
  3. Evidences have identified the correlation of 8-oxoguanine DNA glycosylase-1 (OGG1) and eph-receptor tyrosine kinase-type A2 (EPHA2) polymorphisms in age-related cataract (ARC) risk. However, the results were n...

    Authors: Hongxu Zhang, Jianguang Zhong, Zhenyu Bian, Xiang Fang, You Peng and Yongping Hu
    Citation: BMC Ophthalmology 2016 16:168
  4. Intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) now improve or stabilize visual acuity in a number of previously untreatable eye diseases, of which the main are age-related...

    Authors: Dordi Austeng, Tora Sund Morken, Stine Bolme, Turid Follestad and Vidar Halsteinli
    Citation: BMC Ophthalmology 2016 16:169
  5. Maple syrup urine disease (MSUD) is a rare metabolic disorder, affecting the metabolism of branched chain amino-acids (Valine, Leukine, Isoleukine). We present a rare case of rhegmatogenous retinal detachment ...

    Authors: Menelaos G. Kanakis, Helen Michelakakis, Petros Petrou, Chrysanthi Koutsandrea and Ilias Georgalas
    Citation: BMC Ophthalmology 2016 16:170
  6. In 2014, Pang et al. reported three cases with vitelliform submaculopathy as a preceding lesion of primary intraocular lymphoma (PIOL). Here, we report a case with an atypical presentation of PIOL who initiall...

    Authors: Koji Komatsu, Tsutomu Sakai, Toshikatsu Kaburaki, Hideki Tsuji and Hiroshi Tsuneoka
    Citation: BMC Ophthalmology 2016 16:171
  7. VKH is a rare autoimmune disease. Decreased level of vitamin D has recently been found to be involved in the pathogenesis of Vogt-Koyanagi-Harada (VKH) disease. This study was designed to screen the vitamin D ...

    Authors: Ma’an Abdullah Al-Barry, Alia M Albalawi, Mohammed Abu Sayf, Abdulrahman Badawi, Sibtain Afzal, Muhammad Latif, Mohammed I. Samman and Sulman Basit
    Citation: BMC Ophthalmology 2016 16:172
  8. To assess the efficacy of bandage contact lens (BCL) application to promote epithelialization and alleviate pain following corneal transplantation.

    Authors: Jun Shimazaki, Chika Shigeyasu, Yumiko Saijo-Ban, Murat Dogru and Seika Den
    Citation: BMC Ophthalmology 2016 16:174
  9. Though the development and fitting of scleral contact lenses are expanding steadily, there is no simple method to provide scleral metrics for scleral contact lens fitting yet. The aim of this study was to est...

    Authors: Sang-Mok Lee, Hyuk Jin Choi, Heejin Choi, Mee Kum Kim and Won Ryang Wee
    Citation: BMC Ophthalmology 2016 16:176
  10. Phlyctenular keratitis is a hypersensitivity reaction of the cornea, and a complication of eyelid margin disease in children and young adults. In this study, we compared the morphology of the meibomian glands ...

    Authors: Takashi Suzuki, Naoyuki Morishige, Reiko Arita, Shizuka Koh, Tohru Sakimoto, Rika Shirakawa, Kazunori Miyata and Yuichi Ohashi
    Citation: BMC Ophthalmology 2016 16:178
  11. To compare refractive outcomes after cataract surgery between patients with closed-angle and open-angle glaucoma and evaluate the influence of preoperative factors on refractive outcomes in patients with glauc...

    Authors: Young Cheong Kim, Mi Sun Sung, Hwan Heo and Sang Woo Park
    Citation: BMC Ophthalmology 2016 16:179
  12. To introduce a modified surgical technique, the “parafoveal multiple curvelinear internal limiting membrane (ILM) peeling”, to preserve epi-foveal ILM in myopic foveoschisis surgery.

    Authors: Haiying Jin, Qi Zhang and Peiquan Zhao
    Citation: BMC Ophthalmology 2016 16:180
  13. The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in hea...

    Authors: Mo Yang, Wei Wang, Quangang Xu, Shaoying Tan and Shihui Wei
    Citation: BMC Ophthalmology 2016 16:182
  14. Refractive error is the main cause of visual impairment in the world. Spectacles are the most frequently used options for correcting refractive errors. In addition, they can be used for protection and fashion....

    Authors: Alemayehu Desalegn, Asamer Tsegaw, Destaye Shiferaw and Haile Woretaw
    Citation: BMC Ophthalmology 2016 16:184
  15. Intrachoroidal cavitation (ICC) in the temporal peripapillary area is a relatively frequent finding in high myopia. However, ICC associated with a full thickness retinal defect rarely observed. We report an un...

    Authors: Yoshiyuki Kita, Makoto Inoue, Gábor Hollό, Ritsuko Kita, Masahiko Sano and Akito Hirakata
    Citation: BMC Ophthalmology 2016 16:186
  16. Patients with initially low visual acuity were excluded from the therapy approval studies for retinal vein occlusion. But up to 28 % of patients presenting with central retinal vein occlusion have a baseline B...

    Authors: Sibylle Winterhalter, Gerrit Alexander vom Brocke, Daniel Pilger, Annabelle Eckert, Juliane Schlomberg, Anne Rübsam, Matthias Karl Klamann, Enken Gundlach, Tina Dietrich-Ntoukas and Antonia Maria Joussen
    Citation: BMC Ophthalmology 2016 16:187
  17. In 2014, the overall rate of smartphone use in Korea was 83 and 89.8 % in children and adolescents. The rate of smartphone use differs according to region (urban vs. rural) and age (younger grade vs. older gra...

    Authors: Jun Hyung Moon, Kyoung Woo Kim and Nam Ju Moon
    Citation: BMC Ophthalmology 2016 16:188
  18. To study the value and safety of aqueous humor polymerase chain reaction (PCR) analysis for Herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus and Toxoplasma gondii in patients with uveitis.

    Authors: Argyrios Chronopoulos, Daniel Roquelaure, Georges Souteyrand, Jörg Dieter Seebach, James Scott Schutz and Gabriele Thumann
    Citation: BMC Ophthalmology 2016 16:189
  19. Ocular allergy is a growing public health problem that greatly impacts the day-to-day life of sufferers and their families. Other aspects of their activities of daily living such as schooling, professional, an...

    Authors: Samuel Kyei, Bernard Tettey, Kofi Asiedu and Agnes Awuah
    Citation: BMC Ophthalmology 2016 16:190
  20. The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens.

    Authors: Ibtissem Bouchoucha, Aurore Aziz, Louis Hoffart and Michel Drancourt
    Citation: BMC Ophthalmology 2016 16:191
  21. Congenital cataracts are often complicated by anterior segment dysgenesis. This study aims to compare bilateral anterior segment parameters, macular thickness, and best-corrected visual acuity (BCVA) in pediat...

    Authors: Erping Long, Jingjing Chen, Zhenzhen Liu, Zhuoling Lin, Qianzhong Cao, Xiayin Zhang, Xiaoyan Li, Lixia Luo, Haotian Lin, Weirong Chen and Yizhi Liu
    Citation: BMC Ophthalmology 2016 16:192
  22. Mutations of Crb1 gene cause irreversible and incurable visual impairment in humans. This study aims to use an LCA8-like mouse model to identify host-mediated responses that might interfere with survival, reti...

    Authors: Seo-Hee Cho, Ji Yun Song, Jinyeon Shin and Seonhee Kim
    Citation: BMC Ophthalmology 2016 16:193
  23. Refractive errors, strabismus, nystagmus, amblyopia, and cortical visual impairment are observed in 50 to 90 % of patients with cerebral palsy. Ocular abnormalities are known to differ according to cerebral pa...

    Authors: Myung Jin Park, Yung Ju Yoo, Chin Youb Chung and Jeong-Min Hwang
    Citation: BMC Ophthalmology 2016 16:195
  24. Adult-onset Still’s disease is a systemic inflammatory disease which presents with uveitis and scleritis in the eye. Intravitreal dexamethasone implants are used for the treatment of refractory uveitis.

    Authors: Seong Joon Ahn, Sun Jin Hwang and Byung Ro Lee
    Citation: BMC Ophthalmology 2016 16:196
  25. Surgical outcome of corneal keloid is largely variable depending on reports, although surgical management is inevitable in visually significant cases. We here report clinical features, histopathological findin...

    Authors: Hyo Kyung Lee, Hyuk Jin Choi, Mee Kum Kim, Won Ryang Wee and Joo Youn Oh
    Citation: BMC Ophthalmology 2016 16:198
  26. To evaluate the effect of bradykinin (BK) on TGF-β1-induced retinal pigment epithelial (RPE) cell proliferation and extracellular matrix secretion and to elucidate the relationship between BK and the Erk/Akt s...

    Authors: Wenting Cai, Qingquan Wei, Qingyu Liu, Chengda Ren, Junling Liu, Ruiling Zhang, Mengmei He, Qianyi Wang, Yaru Du and Jing Yu
    Citation: BMC Ophthalmology 2016 16:199
  27. A significant increase in myopia among children and teenagers can be observed all over the world. Yet at the same time, there is still an insignificant number of studies concerning this health problem.

    Authors: Joanna B. Łazarczyk, Beata Urban, Beata Konarzewska, Agata Szulc, Alina Bakunowicz-Łazarczyk, Ewa Żmudzka, Urszula Kowzan, Napoleon Waszkiewicz and Karolina Juszczyk-Zajkowska
    Citation: BMC Ophthalmology 2016 16:201
  28. The Implantable Collamer Lens (ICL) has been used widely for refractive errors, We performed this prospective randomized comparative study to compare postoperative intraocular pressure (IOP) and vaults of the ...

    Authors: Haiting Chen, Guangzeng Niu, Yuxiang Fan and Jingxue Ma
    Citation: BMC Ophthalmology 2016 16:203
  29. Although glaucoma is the lead cause of irreversible blindness globally, the condition shows no signs or symptoms until later stages. Knowledge about the disease is known to influence utilization of eye screeni...

    Authors: Virtue Fiawokome De-Gaulle and Phyllis Dako-Gyeke
    Citation: BMC Ophthalmology 2016 16:204
  30. Corneal biomechanical properties are always compromised after corneal refractive surgeries thus leading to underestimated intraocular pressure (IOP) that complicates the management of IOP. We investigated the ...

    Authors: Yang Shen, Xiangjian Su, Xiu Liu, Huamao Miao, Xuejun Fang and Xingtao Zhou
    Citation: BMC Ophthalmology 2016 16:205
  31. To identify success predictors and to study the role of the fellow untreated eye as a co-variable for adjustment of intraocular pressure (IOP) outcomes following selective laser trabeculoplasty (SLT) in early ...

    Authors: Mikael Chun, Carolina P. B. Gracitelli, Flavio S. Lopes, Luis G. Biteli, Michele Ushida and Tiago S. Prata
    Citation: BMC Ophthalmology 2016 16:206
  32. Closantel is a halogenated salicylanilide with a potent anti parasitic activity. It is widely used in management of parasitic infestation in animals, but is contraindicated in humans.

    Authors: Seyed Ali Tabatabaei, Mohammad Soleimani, Mohammad Reza Mansouri, Ahmad Mirshahi, Bahman Inanlou, Mojtaba Abrishami, Ahmad Reza Pakrah and Hamideh Masarat
    Citation: BMC Ophthalmology 2016 16:207
  33. Corneal ulcer, a major cause of monocular blindness in developing countries has consistently been listed as the major cause of blindness and visual disability in many of the developing nations in Asia, Africa ...

    Authors: Sharmila Suwal, Dinesh Bhandari, Pratigya Thapa, Mohan Krishna Shrestha and Jyoti Amatya
    Citation: BMC Ophthalmology 2016 16:209
  34. It has been suggested that the higher prevalence of cataract in women is caused by a withdrawal effect of oestrogen at menopause. In vitro studies have demonstrated protection of serum oestradiol (E2) against ...

    Authors: Dragana Škiljić, Staffan Nilsson, Anne Petersen, Jan-Olof Karlsson, Anders Behndig, Lada Kalaboukhova and Madeleine Zetterberg
    Citation: BMC Ophthalmology 2016 16:210
  35. To report a case of postoperative fibrous membrane formation occluding the visual axis in the presence of anterior capsular phimosis in a patient with pseudoexfoliation syndrome.

    Authors: Eung Suk Kim, Moosang Kim, Seung-Jun Lee, Sang Beom Han, Hee Kyung Yang and Joon Young Hyon
    Citation: BMC Ophthalmology 2016 16:213
  36. Colour Doppler analysis of ophthalmic vessels has been proposed as a promising tool in the diagnosis of various eye diseases, but the available diagnostic evidence has not yet been assessed systematically. We ...

    Authors: Mario Bittner, Livia Faes, Sophie C. Boehni, Lucas M. Bachmann, Reinier O. Schlingemann and Martin K. Schmid
    Citation: BMC Ophthalmology 2016 16:214

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