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  1. This study aimed to establish a deep learning system for detecting the active and inactive phases of thyroid-associated ophthalmopathy (TAO) using magnetic resonance imaging (MRI). This system could provide fa...

    Authors: Chenyi Lin, Xuefei Song, Lunhao Li, Yinwei Li, Mengda Jiang, Rou Sun, Huifang Zhou and Xianqun Fan
    Citation: BMC Ophthalmology 2021 21:39
  2. To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion.

    Authors: Yi-Zhuo Wang, Yi Zhang, Dong-Sheng Huang, Ji-Tong Shi, Jian-Min Ma, Bin Li, Xiao-Lin Xu, Yan Zhou and Hua-Li Gu
    Citation: BMC Ophthalmology 2021 21:38
  3. Retinitis Pigmentosa (RP) is the most frequent retinal hereditary disease and every kind of transmission pattern has been described. The genetic etiology of RP is extremely heterogeneous and in the last few ye...

    Authors: Marcella Nebbioso, Federica Franzone, Alessandro Lambiase, Maurizio La Cava, Fabiana Mallone, Antonio Pizzuti and Enrica Marchionni
    Citation: BMC Ophthalmology 2021 21:37
  4. To investigate the distribution of corneal astigmatism, aberration, and biometric parameters in Chinese congenital cataract (CC) /developmental cataract patients before cataract surgery.

    Authors: Xiaoyan Han, Qi Fan, Zhixiang Hua, Xiaodi Qiu, Dongjin Qian and Jin Yang
    Citation: BMC Ophthalmology 2021 21:34
  5. Macular edema secondary to retinal vein occlusion (RVO) is an important cause of loss of vision. Intravitreal injections (IVI) of anti-vascular endothelial growth factor (VEGF) are the standard of care in this...

    Authors: Raja Narayanan, Aditya Kelkar, Zahir Abbas, Neha Goel, Manoj Soman, Naveen Naik, Aditya Sudhalkar, Jaydeep Walinjkar, Utkarsh Shah and Nitin Maksane
    Citation: BMC Ophthalmology 2021 21:33
  6. Precise optic disc size measurements based on anatomically exact disc margins are fundamental for a correct assessment of glaucoma suspects. Computerized imaging techniques, such as confocal-scanning-laser-tom...

    Authors: Ioana Maria Cazana, Daniel Böhringer, Thomas Reinhard, Charlotte Evers, Diana Engesser, Alexandra Anton and Jan Lübke
    Citation: BMC Ophthalmology 2021 21:31
  7. Central serous chorioretinopathy (CSC) is characterized by an accumulation of subretinal fluid (SRF) in the macula. It is usually treated by laser photocoagulation or photodynamic therapy (PDT) with consisting...

    Authors: Jirarattanasopa Pichai, Banchasakjaroen Vanchalerm and Ratanasukon Mansing
    Citation: BMC Ophthalmology 2021 21:30
  8. To investigate the microbiologic spectrum of dacryocystitis in adult and pediatric groups, specifically the microbiologic differences between chronic dacryocystitis with nasolacrimal duct obstruction (NLDO) an...

    Authors: Ban Luo, Mu Li, Nan Xiang, Weikun Hu, Rong Liu and Xiaoqin Yan
    Citation: BMC Ophthalmology 2021 21:29
  9. Severe congenital ophthalmological malformations and glaucoma might be an important occasional feature in patients with Coffin-Siris syndrome (CSS), especially Coffin-Siris syndrome 9 (CSS9, OMIM #615866) caus...

    Authors: Heidi Diel, Can Ding, Franz Grehn, Panagiotis Chronopoulos, Oliver Bartsch and Esther M. Hoffmann
    Citation: BMC Ophthalmology 2021 21:28

    The Correction to this article has been published in BMC Ophthalmology 2021 21:57

  10. To compare the aqueous humor (AH) and the serum clusterin levels of patients with pseudoexfoliation syndrome (PEX), pseudoexfoliation glaucoma (PEXG), and primary open-angle glaucoma (POAG) with each other and...

    Authors: Fuat Yavrum, Ufuk Elgin, Zeynep Adiyaman Kocer, Vildan Fidanci and Emine Sen
    Citation: BMC Ophthalmology 2021 21:25
  11. Orbital aspergillosis is a rare sight- and life-threatening fungal infection affecting immunocompromised or otherwise healthy patients. It is often misdiagnosed due to its unspecific clinical and radiologic ap...

    Authors: Mael Lever, Benjamin Wilde, Roman Pförtner, Cornelius Deuschl, Oliver Witzke, Stefanie Bertram, Anja Eckstein and Peter-Michael Rath
    Citation: BMC Ophthalmology 2021 21:22
  12. Implantation of the posterior chamber phakic intraocular lens has been widely performed to correct high and extreme myopia. Chronic intraocular pressure (IOP) elevation may occur in its late postoperative peri...

    Authors: Rongrong Hu, Wei Xu, Baishuang Huang and Xiaoyu Wang
    Citation: BMC Ophthalmology 2021 21:20
  13. The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stabili...

    Authors: Shangfei Yang, Hui Jiang, Kailai Nie, Liwen Feng and Wei Fan
    Citation: BMC Ophthalmology 2021 21:19
  14. Early detection of glaucoma is paramount to maintain patients’ eyesight, however glaucomatous vision loss tends to begin in the periphery with up to 50% of patients unaware they are affected. Because glaucomat...

    Authors: Anna Neustaeter, Ilja Nolte, Harold Snieder and Nomdo M. Jansonius
    Citation: BMC Ophthalmology 2021 21:18
  15. Ultrasound cycloplasty (UCP) is a non-invasive procedure for glaucoma treatment. Using high-intensity focused ultrasound to work on the ciliary body, the generation of aqueous humor can be reduced and the drai...

    Authors: Jihan Luo, Zhen Liu, Lin Zhao, Yi Zhou, Li Kong and Yang Sun
    Citation: BMC Ophthalmology 2021 21:16
  16. The World Health Organization (WHO) recommends annual mass azithromycin distribution until districts drop below 5% prevalence of trachomatous inflammation—follicular (TF). Districts with very low TF prevalence...

    Authors: Abdou Amza, Boubacar Kadri, Beido Nassirou, Ahmed M. Arzika, Ariana Austin, Fanice Nyatigo, Elodie Lebas, Benjamin F. Arnold, Thomas M. Lietman and Catherine E. Oldenburg
    Citation: BMC Ophthalmology 2021 21:15
  17. The treatment efficacy of botulinum toxin bilateral medial rectus injections for acute acquired concomitant esotropia (AACE) in adult is not clear. We characterize the effects of botulinum toxin injection in t...

    Authors: Minghua Shi, Yuanxiang Zhou, Aijiao Qin, Jing Cheng and Hongxing Ren
    Citation: BMC Ophthalmology 2021 21:9
  18. However there have been numerous investigations of intrascleral intraocular lens (IOL) fixation techniques, there is room for improvement in terms of simplifying complicated techniques and reducing the high le...

    Authors: Tatsuya Jujo, Jiro Kogo, Hiroki Sasaki, Reio Sekine, Keiji Sato, Sakura Ebisutani, Yasuhiro Toyoda, Yasushi Kitaoka and Hitoshi Takagi
    Citation: BMC Ophthalmology 2021 21:8
  19. A prospective cohort study was performed to evaluate whether the Optical Quality Analysis System (OQAS) can serve as a valuable additional indicator for appropriate posterior capsulotomy referral.

    Authors: Bo Lu, Weijie Zhu, Yu Fan, Dong Shi and Liwei Ma
    Citation: BMC Ophthalmology 2021 21:7
  20. Sturge-Weber syndrome (SWS) is a sporadic congenital disorder, characterized by unilateral facial nevus flammeus associated with ipsilateral glaucoma, choroidal angioma and leptomeningeal hemangiomas. SWS can ...

    Authors: Hongxi Wang, Nana Dong, Li Tan and Chukai Huang
    Citation: BMC Ophthalmology 2021 21:6
  21. To study the enlargement rate of primary geographic atrophy (GA) before and after diagnosis of a secondary choroidal neovascularization (CNV) treated with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Jakob Siedlecki, Caroline Koch, Benedikt Schworm, Raffael Liegl, Thomas Kreutzer, Karsten U. Kortuem, Ricarda Schumann, Siegfried G. Priglinger and Armin Wolf
    Citation: BMC Ophthalmology 2021 21:4
  22. To assess the prevalence and demographics of lower eyelid epiblepharon in Chinese preschool children and to evaluate its association with refractive errors.

    Authors: Deyi Zhuo, Si Chen, Xiaofang Ren, Bingsong Wang, Linbo Liu and Lin Xiao
    Citation: BMC Ophthalmology 2021 21:3
  23. To compare different clinical and Spectral-Domain Optical Coherence Tomography (SD-OCT) features of high myopic eyes with Stickler syndrome (STL) with matched controls.

    Authors: Olivia Xerri, Federico Bernabei, Elise Philippakis, Cyril Burin-Des-Roziers, Pierre-Olivier Barale, Olivier Laplace, Claire Monin, Dominique Bremond-Gignac, Gilles Guerrier, Sophie Valleix, Antoine Brezin and Pierre-Raphaël Rothschild
    Citation: BMC Ophthalmology 2021 21:2
  24. Vision loss is a major public health concern that significantly affects developing countries, including South Africa. Although existing literature have reported on the prevalence, causes, and impact of vision ...

    Authors: Emmanuel Kofi Addo, Kwadwo Owusu Akuffo, Ronel Sewpaul, Natisha Dukhi, Eldad Agyei-Manu, Akosua Kesewah Asare, David Ben Kumah, Moses Awuni and Priscilla Reddy
    Citation: BMC Ophthalmology 2021 21:1
  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jaeryung Kim, Sung-Ho Choi, Dong Hui Lim, Gil-Joong Yoon and Tae-Young Chung
    Citation: BMC Ophthalmology 2020 20:492

    The original article was published in BMC Ophthalmology 2020 20:192

  26. The purpose of the study was to explore the immunological components that are responsible for the proliferative alterations in the different forms of retinal detachment (RD).

    Authors: Anikó Balogh, Tibor Milibák, Viktória Szabó, Zoltán Zsolt Nagy, Kai Kaarniranta and Miklós D. Resch
    Citation: BMC Ophthalmology 2020 20:491
  27. The aim of this retrospective study was to compare the efficacy and safety profile of a single XEN-microstent in different types of primary and secondary open angle glaucoma.

    Authors: Marc Schargus, Theresa Theilig, Matus Rehak, Catharina Busch, Caroline Bormann and Jan Darius Unterlauft
    Citation: BMC Ophthalmology 2020 20:490
  28. Anterior uveitis secondary to topical brimonidine administration is rare and not well-defined. In glaucoma patients using brimonidine, one must consider this phenomenon to avoid mis-diagnosis and over-treatmen...

    Authors: Susanne Hopf, Karl Mercieca, Norbert Pfeiffer and Verena Prokosch-Willing
    Citation: BMC Ophthalmology 2020 20:489
  29. Collagen cross-linking of the sclera is a promising approach to strengthen scleral rigidity and thus to inhibit eye growth in progressive myopia. Additionally, cross-linking might inhibit degrading processes i...

    Authors: Konstantin Krasselt, Cornelius Frommelt, Robert Brunner, Franziska Georgia Rauscher, Mike Francke and Nicole Körber
    Citation: BMC Ophthalmology 2020 20:488
  30. Choroidal ganglioneuroma is an extremely rare tumor, and there is little knowledge regarding its pathogenesis. We aimed to investigate the phenotypic and genetic alterations in one sporadic patient with a rare...

    Authors: Zhaoxin Jiang, Ting Zhang, Chonglin Chen, Limei Sun, Songshan Li and Xiaoyan Ding
    Citation: BMC Ophthalmology 2020 20:487
  31. Chorioretinal fold (CFs) is a rare condition resulting from undulations in the choriocapillaris, Bruch's membrane, retinal pigment epithelium and occasionally neurosensory retina. It can be idiopathic or due t...

    Authors: Nan-Ni Chen, Chien-Hsiung Lai, Tsai Yueh-Ju and Chau -Yin Chen
    Citation: BMC Ophthalmology 2020 20:486
  32. Usher syndrome is a disease with a heterogeneous phenotype and genotype. Our purpose was to identify the gene mutation in a Chinese family with Usher syndrome type 2 and describe the clinical features.

    Authors: Dongjun Xing, Huaiyu Zhou, Rongguo Yu, Linni Wang, Liying Hu, Zhiqing Li and Xiaorong Li
    Citation: BMC Ophthalmology 2020 20:485
  33. We have generated two mouse models, in one by inserting the human lens αAN101D transgene in CRYαAN101D mice, and in the other by inserting human wild-type αA-transgene in CRYαAWT mice. The CRYαAN101D mice develop...

    Authors: Om Srivastava, Kiran Srivastava, Roy Joseph and Landon Wilson
    Citation: BMC Ophthalmology 2020 20:484
  34. Choroidal neovascularization (CNV) in pregnancy has rarely been described. A differential diagnosis between inflammatory, idiopathic, and myopic CNV may be challenging. Moreover, there is no consensus on manag...

    Authors: Emilia Maggio, Maurizio Mete, Antonio Polito, Gloria Parrozzani and Grazia Pertile
    Citation: BMC Ophthalmology 2020 20:483

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