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  1. Medical big data analytics has revolutionized the human healthcare system by introducing processes that facilitate rationale clinical decision making, predictive or prognostic modelling of the disease progress...

    Authors: Praveen Raj, Sushma Tejwani, Dandayudhapani Sudha, B. Muthu Narayanan, Chandrasekar Thangapandi, Sankar Das, J. Somasekar, Susmithasane Mangalapudi, Durgesh Kumar, Narendra Pindipappanahalli, Rohit Shetty, Arkasubhra Ghosh, Govindasamy Kumaramanickavel, Amitabha Chaudhuri and Nagasamy Soumittra
    Citation: BMC Ophthalmology 2020 20:442
  2. To understand the differences between two different optical coherence tomography angiography (OCTA) devices in detecting glaucomatous from healthy eyes by comparing their vascular parameters, diagnostic accura...

    Authors: A. R. Kee, V. C. H. Yip, E. L. T. Tay, C. W. Lim, J. Cheng, H. Y. Teo, C. H. Chua and L. W. L. Yip
    Citation: BMC Ophthalmology 2020 20:440
  3. The Prevalence of myopia is increasing in China. This study aimed to explore the distribution of spherical equivalent (SE) and its association with age, body mass index (BMI), gender in a non-myopic Chinese ch...

    Authors: Xiyan Zhang, Yonglin Zhou, Jie Yang, Yan Wang, Wenyi Yang, Liuwei Gao, Yao Xiang and Fengyun Zhang
    Citation: BMC Ophthalmology 2020 20:439
  4. The tear film breakup time (tBUT) is a clinical evaluation of evaporative dry eye disease assessed by instilling topical fluorescein into the eyes. In the present study, we introduce a new diagnostic test, bli...

    Authors: Hyung Bin Hwang, Yong Ho Ku, Eun Chul Kim, Hyun Seung Kim, Man Soo Kim and Ho Sik Hwang
    Citation: BMC Ophthalmology 2020 20:438
  5. In this case report, we present for the first time central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) as a complication of persistent hyaloid artery (PHA).

    Authors: Mirjana Bjeloš, Ana Križanović, Mladen Bušić and Biljana Kuzmanović Elabjer
    Citation: BMC Ophthalmology 2020 20:434
  6. Hurler syndrome-associated keratopathy is an exceedingly rare corneal disorder that requires corneal transplantation in advanced stages. Precise assessment of the corneal condition is necessary for deciding wh...

    Authors: Elodie Da Cunha, Cristina Georgeon, Nacim Bouheraoua, Marc Putterman, Françoise Brignole-Baudouin and Vincent M. Borderie
    Citation: BMC Ophthalmology 2020 20:433
  7. At present, patients with ocular myasthenia gravis (OMG) are typically treated with systemic drugs. We investigated the use of dexamethasone injected in the peribulbar region or extraocular muscle to treat pat...

    Authors: Minghua Shi, Yingjia Ye, Junping Zhou, Aijiao Qin, Jing Cheng and Hongxing Ren
    Citation: BMC Ophthalmology 2020 20:432
  8. Numerous cytokines have been proven to participate in the pathogenesis of neovascular age-related macular degeneration (nAMD). The present study aimed to investigate the aqueous humor cytokine expression profi...

    Authors: Kailin Chen, Wen Xu, Jiao Zheng, Yupeng Shen, Jian Ma and Zhiqing Chen
    Citation: BMC Ophthalmology 2020 20:431
  9. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Alexandra Graf, Katharina Krepler and Siamak Ansari-Shahrezaei
    Citation: BMC Ophthalmology 2020 20:430

    The original article was published in BMC Ophthalmology 2020 20:381

  10. Central retinal vein occlusion is a variable disease pattern. Preliminary stages of a complete occlusion of the central vein, wich are subsumed under the term venous stasis retinopathy, may occur as transient ...

    Authors: Julia V. Stingl, Laura Ponce Nunez, Alexander K. Schuster and Esther M. Hoffmann
    Citation: BMC Ophthalmology 2020 20:428
  11. Perfluorocarbon liquid (PFCL) is an effective surgical adjuvant in performing vitrectomy for severe vitreoretinal pathologies such as proliferative vitreoretinopathy and giant retinal tears. However, subretina...

    Authors: Kosuke Takahashi, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Shinichiro Doi, Ryo Matoba, Yuki Kanzaki, Yoshihiro Yonekawa and Yuki Morizane
    Citation: BMC Ophthalmology 2020 20:427
  12. Neurofibromatosis type 1 (NF1) is a hereditary disease that causes neurofibromas generally, but it has been reported to sometimes be associated with various forms of blood vessel stenosis, occlusion and vascul...

    Authors: Hiroaki Sakai, Kosuke Kawata, Jun Masuoka, Tomohisa Nishimura and Hiroshi Enaida
    Citation: BMC Ophthalmology 2020 20:426
  13. Extraskeletal osteosarcoma is a malignant tumour composed of an osteoid and/or cartilaginous matrix; it arises in soft tissues without connection to the skeleton, and to our knowledge, this type of tumour is e...

    Authors: Jingwen Hui, Yun Zhao, Lei Zhang, Jinyong Lin and Hong Zhao
    Citation: BMC Ophthalmology 2020 20:425
  14. To prevent irreversible vision loss in age-related macular degeneration (AMD), it is critical to detect retinal dysfunction before permanent structural loss occurs. In the current study we evaluated a series o...

    Authors: Divya Narayanan, John Rodriguez, Garrick Wallstrom, Donna Welch, Matthew Chapin, Paul Arrigg and Mark Abelson
    Citation: BMC Ophthalmology 2020 20:424
  15. To investigate the difference in retinal nerve fiber layer (RNFL) thickness, choroidal thickness (CT) and superficial retinal vessels between thyroid-associated ophthalmopathy (TAO) patients and healthy contro...

    Authors: Lanchu Yu, Qin Jiao, Yu Cheng, Yanji Zhu, Zhongjing Lin and Xi Shen
    Citation: BMC Ophthalmology 2020 20:421
  16. Few studies have evaluated the surgical outcome of superior oblique weakening procedures in patients with superior oblique overaction associated with exotropia or esotropia. This study aimed to evaluate the ou...

    Authors: Junwoo Chun and Seong-Joon Kim
    Citation: BMC Ophthalmology 2020 20:420
  17. Driving simulators are a safe alternative to on-road vehicles for studying driving behavior in glaucoma drivers. Visual field (VF) loss severity is associated with higher driving simulator crash risk, though m...

    Authors: David E. Anderson, John P. Bader, Emily A. Boes, Meghal Gagrani, Lynette M. Smith, Jideofor K. Ndulue, Sachin Kedar, Vikas Gulati, Deepta A. Ghate and Matthew Rizzo
    Citation: BMC Ophthalmology 2020 20:419
  18. Ocular coloboma is an excavation of ocular structures that occurs due to abnormal fusion of the embryonic optic fissure. Further, cleft lip/palate (CL/P), a congenital midline abnormality, is caused by a defec...

    Authors: Yung Ju Yoo, Sang Beom Han, Hee Kyung Yang and Jeong-Min Hwang
    Citation: BMC Ophthalmology 2020 20:418
  19. Proliferative diabetic retinopathy (PDR) is one of the most common cause of vision loss in diabetic patients, and the incidence age of PDR patients gradually gets younger. This study aims to compare the charac...

    Authors: Mengyu Liao, Xiaohong Wang, Jinguo Yu, Xiangda Meng, Yuanyuan Liu, Xue Dong, Jianan Li, Rodrigo Brant, Bo Huang and Hua Yan
    Citation: BMC Ophthalmology 2020 20:416
  20. Congenital orbital teratoma is relatively rare, and few reports of prenatal ultrasound findings in such cases have been published.

    Authors: Xi Chen, Jiaxiang Yang, Guannan He, Chunlan Cheng, Chunguo Zhang, Hongli Wang, Lihong He, Zhirong Yang, Li Chen and Jing Zhao
    Citation: BMC Ophthalmology 2020 20:415
  21. Whipple’s disease (WD) is a rare, chronic, infection caused by gram-positive filamentous aerobic actinobacterium Tropheryma whipplei occurs classically in the gastrointestinal tract and shows histopathological...

    Authors: Waleed K. Alsarhani, Muhannad I. Alkhalifah, Hind M. Alkatan, Afaf L. Alsolami, Azza M. Y. Maktabi and Adel H. Alsuhaibani
    Citation: BMC Ophthalmology 2020 20:413
  22. Primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid is an extremely rare but aggressive neoplasm diagnosed primarily in elderly men. Until now there are 32 published cases of signet-ring ce...

    Authors: Mathew M. Palakkamanil, Muhammad N. Mahmood and Audrey Chan
    Citation: BMC Ophthalmology 2020 20:410
  23. To date there have been few systematic attempts to establish the general prevalence of asthenopia in unselected populations of school-aged children. Thus, the aim of this study was to determine whether the inc...

    Authors: Barbara M. Junghans, Serap Azizoglu and Sheila G. Crewther
    Citation: BMC Ophthalmology 2020 20:408
  24. It is necessary to consider myopic optic disc tilt as it seriously impacts normal ocular parameters. However, ophthalmologic measurements are within inter-observer variability and time-consuming to get. This s...

    Authors: Baek Hwan Cho, Da Young Lee, Kyung-Ah Park, Sei Yeul Oh, Jong Hak Moon, Ga-In Lee, Hoon Noh, Joon Kyo Chung, Min Chae Kang and Myung Jin Chung
    Citation: BMC Ophthalmology 2020 20:407
  25. Glaucoma surgery have been developed to lower intraocular pressure in a less invasive manner than traditional glaucoma surgery. The purpose of this article is to determine the outcome of using combined phacoem...

    Authors: Juan Carlos Izquierdo, Josefina Mejías, Laura Cañola-R, Natalia Agudelo and Bárbara Rubio
    Citation: BMC Ophthalmology 2020 20:406
  26. Diabetic macular edema (DME) is the most common cause of vision loss in diabetic patients. As India has the second largest population of diabetic patients worldwide, availability of various treatment options f...

    Authors: Unnikrishnan Nair, Vishali Gupta, Mohita Sharma, Shrinivas Joshi, Aditya Sudhalkar, Undraa Altangerel and Yan Bai
    Citation: BMC Ophthalmology 2020 20:405
  27. We conducted this study to report on the indications and types of retinal laser therapy (RLT) performed in Bhutan, knowing which is critical for proper planning and successful delivery of the services.

    Authors: Bhim B. Rai, Michael G. Morley, Pema Zangmo, Thukten Tshering, Abi N. Khatiwara, Paul S. Bernstein and Ted Maddess
    Citation: BMC Ophthalmology 2020 20:404
  28. Although nasolacrimal duct probing is the standard treatment for congenital nasolacrimal duct obstruction (CNLDO) among children, the optimal timing of this procedure has been a topic of debate. The aim of the...

    Authors: Marta Świerczyńska, Ewelina Tobiczyk, Piotr Rodak, Dorota Barchanowska and Erita Filipek
    Citation: BMC Ophthalmology 2020 20:403
  29. Optical coherence tomography angiography (OCTA) is a newly developed imaging quantitative technique for analysis of choriocapillaris (CC) flow changes, thereby exploring the pathological mechanism of chronic c...

    Authors: Juejun Liu, Changzheng Chen, Lu Li, Yishuang Xu, Zuohuizi Yi, Lu He and Hongmei Zheng
    Citation: BMC Ophthalmology 2020 20:402

    The Correction to this article has been published in BMC Ophthalmology 2020 20:445

  30. The quality of life can be impacted negatively by blindness arising from cataract. The total prevalence of blindness in Kenya is estimated at 0.7%, however cataract contributes almost half (43%) of the total b...

    Authors: Shadrack Muma and Stephen Obonyo
    Citation: BMC Ophthalmology 2020 20:401
  31. Paclitaxel (PTX) is an antineoplastic drug widely used in treatments for ovarian, breast, and small-cell lung cancer. Although ocular effects associated with PTX have been previously described, very few studie...

    Authors: Amardeep Sekhon, Jeff Y. F. Wang, Johnson C. H. Tan, Simon P. Holland and Sonia N. Yeung
    Citation: BMC Ophthalmology 2020 20:400
  32. Here we report a case of traction retinal detachment (TRD) associated with congenital retinal vascular hypoplasia localized in the superotemporal quadrant that was treated with vitrectomy.

    Authors: Tomomi Miyamoto, Takatoshi Kobayashi, Teruyo Kida, Takaki Sato, Masanori Fukumoto and Tsunehiko Ikeda
    Citation: BMC Ophthalmology 2020 20:398
  33. To evaluate the correlations between lipid layer thickness (LLT) and morphology and function of the meibomian glands in patients who were diagnosed as meibomian gland dysfunction (MGD) in different age groups.

    Authors: Junhua Li, Jiling Ma, Man Hu, Jianqin Yu and Yune Zhao
    Citation: BMC Ophthalmology 2020 20:394
  34. To compare the efficacy and safety of ab externo circumferential trabeculotomy (ECT) and canaloplasty on primary open angle glaucoma (POAG) patients with failed filtering surgery and intact schlemm’s canal (SC).

    Authors: Huaizhou Wang, Chen Xin, Ying Han, Yan Shi, Sarah Ziaei and Ningli Wang
    Citation: BMC Ophthalmology 2020 20:389

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