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  1. This study aimes to characterize the fundus structural changes in patients with nonarteritic anterior ischemic optic neuropathy (NAION) and the correlation between macular vessel density, retinal nerve fibre l...

    Authors: Hui Wang, Zhao-yang Meng, Song-guo Li, Jing-jing Wang, Jiao Sun and Hong-yang Li
    Citation: BMC Ophthalmology 2018 18:341
  2. This was an updated network meta-analysis (NMA) of anti-vascular endothelial growth factor (VEGF) agents and laser photocoagulation in patients with diabetic macular edema (DME). Unlike previous NMA that used ...

    Authors: Dominic Muston, Jean-Francois Korobelnik, Tim Reason, Neil Hawkins, Ismini Chatzitheofilou, Fay Ryan and Peter K. Kaiser
    Citation: BMC Ophthalmology 2018 18:340
  3. To assess a possible signal drift, noise and influences of electromagnetic radiation on the measurement behaviour of the Triggerfish® contact lens sensor, which might be mistaken as IOP fluctuations.

    Authors: Dieter Franz Rabensteiner, Jasmin Rabensteiner and Christoph Faschinger
    Citation: BMC Ophthalmology 2018 18:338
  4. Conventional corneal cross-linking is effective for retarding the progression of keratoconus. However the long-term efficacy and safety of accelerated (45 mW/cm2) transepithelial corneal cross-linking (ATE-CXL...

    Authors: Jinrong Huang, Yang Shen, Weijun Jian, Haipeng Xu, Meiyan Li, Jing Zhao, Xingtao Zhou and Hongfei Liao
    Citation: BMC Ophthalmology 2018 18:337
  5. Cornea protects the eye against natural and anthropogenic ultraviolet (UV) damage and mechanical injury. Corneal incisions produced by UV lasers in ophthalmic surgeries are often complicated by oxidative stres...

    Authors: Evgeni Yu. Zernii, Olga S. Gancharova, Veronika V. Tiulina, Andrey A. Zamyatnin Jr, Pavel P. Philippov, Viktoriia E. Baksheeva and Ivan I. Senin
    Citation: BMC Ophthalmology 2018 18:336
  6. External ophtalmomyiasis (EOM) is a zoonosis related to the presence of Oestrus ovis larvae at the ocular level in small ruminants (i.e. ovine, caprine). In humans, EOM is a rare cosmopolitan disorder, mostly des...

    Authors: Louise Basmaciyan, Pierre-Henry Gabrielle, Stéphane Valot, Marc Sautour, Jean-Christophe Buisson, Catherine Creuzot-Garcher and Frédéric Dalle
    Citation: BMC Ophthalmology 2018 18:335
  7. The optical density of the cornea can be evaluated quantitatively by “densitometry” using a rotating Scheimpflug camera. Densitometry allows evaluation of corneal opacity in the anterior segment of the eye by ...

    Authors: Sho Ishikawa, Naoko Kato and Masaru Takeuchi
    Citation: BMC Ophthalmology 2018 18:334
  8. To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world ...

    Authors: Polona Jaki Mekjavić, Bogdan Gregorčič, Cvetka Oberč and Slava Podgoršek
    Citation: BMC Ophthalmology 2018 18:333
  9. The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR).

    Authors: Takao Hirano, Akira Imai, Hirotsugu Kasamatsu, Shinji Kakihara, Yuichi Toriyama and Toshinori Murata
    Citation: BMC Ophthalmology 2018 18:332
  10. A substantial number of epidemiological studies have investigated the possible associations between sunlight exposure and Age-related Macular Degeneration (AMD), but the results from studies are inconsistent. ...

    Authors: Hongjie Zhou, Huina Zhang, Aiqing Yu and Jiajun Xie
    Citation: BMC Ophthalmology 2018 18:331
  11. Orbital vascular malformation often encircles normal tissue with ill-defined borders. It is easy to bleed during resection operation, making surgical treatment difficult and lesions hard to be removed complete...

    Authors: Tingting Lin, Limin Zhu and Yanjin He
    Citation: BMC Ophthalmology 2018 18:330
  12. To describe the effectiveness of combined pentagonal resection and inferior retractor plication (PR + IRP) based on the Hill’s procedure for the treatment of primary involutional lower eyelid entropion in the ...

    Authors: Janice J. C. Cheung, Carlos K. H. Wong and Leanne T. Y. Cheung
    Citation: BMC Ophthalmology 2018 18:329
  13. Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogeni...

    Authors: Alexios J. Aletras, Ioannis Trilivas, Maria-Elpida Christopoulou, Sotiria Drakouli, Constantine D. Georgakopoulos and Nikolaos Pharmakakis
    Citation: BMC Ophthalmology 2018 18:328
  14. To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA).

    Authors: Mengyang Li, Enzhong Jin, Chongya Dong, Chuan Zhang, Mingwei Zhao and Jinfeng Qu
    Citation: BMC Ophthalmology 2018 18:326
  15. To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous n...

    Authors: Hiroto Terasaki, Shozo Sonoda, Naoko Kakiuchi, Hideki Shiihara, Takehiro Yamashita and Taiji Sakamoto
    Citation: BMC Ophthalmology 2018 18:324
  16. Leber’s hereditary optic neuropathy (LHON) is a maternally inherited recessive disease rarely complicated with glaucoma. We conducted a clinical and genetic retrospective case series to describe three cases of...

    Authors: Yun-Hsuan Lin, Nan-Kai Wang, Ling Yeung, Chi-Chun Lai and Lan-Hsin Chuang
    Citation: BMC Ophthalmology 2018 18:323
  17. This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs).

    Authors: Emi Morimoto, Yoshiaki Shimada, Mitsuo Sugimoto, Tadashi Mizuguchi, Atsuhiro Tanikawa and Masayuki Horiguchi
    Citation: BMC Ophthalmology 2018 18:322
  18. Changes in retinal fluid patterns associated with circumscribed choroidal hemangioma (CCH) have not been investigated yet. A long-term follow-up study was performed to evaluate the changes of retinal fluid pat...

    Authors: Junwon Lee, Christopher Seungkyu Lee, Min Kim and Sung Chul Lee
    Citation: BMC Ophthalmology 2018 18:321
  19. To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma.

    Authors: Bradley H. Jacobsen, Christopher Ricks and Roger P. Harrie
    Citation: BMC Ophthalmology 2018 18:320

    The Correspondence to this article has been published in BMC Ophthalmology 2019 19:193

  20. Doyne honeycomb retinal dystrophy (DHRD)/malattia leventinese (ML) is a rare allelic condition with massive drusen in the posterior fundus caused by EFEMP1 gene mutation. Patients showed decreased vision when the...

    Authors: Kaiyan Zhang, Xuyang Sun, Yingying Chen, Qionglei Zhong, Lin Lin, Yuan Gao and Fanlin Hong
    Citation: BMC Ophthalmology 2018 18:318
  21. This report highlights a rare case of simultaneous bilateral blindness due to posterior ischemic optic neuropathy. Typically, ophthalmic involvement in giant cell arteritis is monocular or sequential ischemia ...

    Authors: Anas Mohammad Albarrak, Yousef Mohammad, Sajjad Hussain, Sufia Husain and Taim Muayqil
    Citation: BMC Ophthalmology 2018 18:317
  22. Ingrowth of newly formed blood and lymph vessels (angiogenesis) from the limbus region into the cornea can be treated successfully by subconjunctival application of antiangiogenic agents. Currently, there are ...

    Authors: Patrick R. Merz, Nina Röckel, Seda Ballikaya, Gerd U. Auffarth and Ingo Schmack
    Citation: BMC Ophthalmology 2018 18:316
  23. Despite the potential usefulness of optical coherence tomography angiography in retinal and optic disc conditions, the reliability of the imaging modality remains unclear. This study set out to measure the mic...

    Authors: Ching Wei Lim, Jun Cheng, Elton Lik Tong Tay, Hwei Yee Teo, Elizabeth Poh Ying Wong, Vernon Khet Yau Yong, Boon Ang Lim, Owen Kim Hee, Hon Tym Wong and Leonard Wei Leon Yip
    Citation: BMC Ophthalmology 2018 18:315
  24. The purpose of this study is to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections to treat cytomegalovirus retinitis in patients without human immunodeficien...

    Authors: Zhuyun Qian, Haili Li, Yong Tao and Wensheng Li
    Citation: BMC Ophthalmology 2018 18:314
  25. Patients with retinal diseases frequently complain of poor visual function even when visual acuity is relatively unaffected. This clinical finding has been attributed to deficits in contrast sensitivity (CS). ...

    Authors: Badr O. Alahmadi, Amro A. Omari, Maria Fernanda Abalem, Chris Andrews, Dana Schlegel, Kari H. Branham, Naheed W. Khan, Abigail Fahim and Thiran Jayasundera
    Citation: BMC Ophthalmology 2018 18:313
  26. Cystoid macular oedema (CMO) is an uncommon complication associated with hydroxychloroquine (HCQ) retinopathy threatening central vision. We report a patient with HCQ retinopathy and CMO, for which an intravit...

    Authors: Seong Joon Ahn, Jooyoung Joung, Sang Hyup Lee and Byung Ro Lee
    Citation: BMC Ophthalmology 2018 18:310
  27. The corneal epithelium is directly affected in dry eye syndrome. Thus, we attempted to describe the morphological features and evaluate the cellular density within the corneal epithelial layers in patients wit...

    Authors: Olivia L. Lee, Tudor C. Tepelus, Jianyan Huang, Anne G. Irvine, Christopher Irvine, Gloria B. Chiu and SriniVas R. Sadda
    Citation: BMC Ophthalmology 2018 18:309
  28. Following publication of the original article [1], the authors notified us of that due to miscommunication during proofing their given names were not presented in their full form, but only using the initials.

    Authors: Seung Wan Nam, Dong Hui Lim, Kyu Yeon Cho, Hye Seung Kim, Kyunga Kim and Tae-Young Chung
    Citation: BMC Ophthalmology 2018 18:308

    The original article was published in BMC Ophthalmology 2018 18:263

  29. Severe retinopathy of prematurity (ROP) with extremely unfavorable prognosis among infants can do great damage to individuals and bring tremendous social-economic burden. The purpose of this study is to descri...

    Authors: Guo-rui Dou, Man-hong Li, Zi-feng Zhang, Yi-na Lu, Yan-ni Zhu, Hai-yan Wang, Jing Wang, Xiao-jie Wang, Jing Fan and Yu-sheng Wang
    Citation: BMC Ophthalmology 2018 18:307
  30. Although there are limited studies, recent data are lacking to accurately determine the magnitude of color blindness in Ethiopia and there is no evidence of such a study in Gish Abay town district. The purpose...

    Authors: Mengistu Zelalem Wale, Yekoye Abebe, Yilikal Adamu and Abebe Zelalem
    Citation: BMC Ophthalmology 2018 18:306
  31. Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, review...

    Authors: Ahmet Murat Sarici, Burak Mergen, Velittin Oguz and Cezmi Dogan
    Citation: BMC Ophthalmology 2018 18:305
  32. A rodent model of photodynamic AION resulting from intravenous verteporfin is presented. The analysis of the morphological function, the pathological changes and the potential mechanism of action were further ...

    Authors: Jing-yu Min, Yanan Lv, Lei Mao, Yuan-yuan Gong, Qing Gu and Fang Wei
    Citation: BMC Ophthalmology 2018 18:304
  33. To investigate the concentrations of oxidative stress markers, 8-hydroxy-2′-deoxyquanosine (8-OHdG) and malondialdehyde (MDA), in tears and their correlation with the clinical activity score (CAS) in patients ...

    Authors: Won Choi, Ying Li, Yong Sok Ji and Kyung Chul Yoon
    Citation: BMC Ophthalmology 2018 18:303
  34. Retinopathy of prematurity (ROP) is a vascular proliferative disorder of the developing retina and a significant cause of childhood blindness around the world. The incidence of ROP is affected by many factors,...

    Authors: Yunxia Leng, Wenzhi Huang, Guoliang Ren, Cheng Cai, Qingbiao Tan, Yuqin Liang, Weizhong Yang and Zongyin Gao
    Citation: BMC Ophthalmology 2018 18:301
  35. The role of histone deacetylases 6 (HDAC6) has been elucidated in various neurodegenerative diseases. However, the effect of HDAC6 on retinal degenerative processes remains unknown. The aim of this study was t...

    Authors: Haihong Yuan, Hui Li, Ping Yu, Qichen Fan, Xuan Zhang, Wei Huang, Junyi Shen, Yongyao Cui and Wei Zhou
    Citation: BMC Ophthalmology 2018 18:300
  36. Granulomatosis with polyangiitis (GPA), a necrotizing granulomatous disease, very rarely involves the central nervous system (CNS), particularly the pituitary. Delayed treatment may cause permanent bilateral b...

    Authors: Xia Zhang, Bing Xing, Hui You, Huanwen Wu, Yong Zhong and Jin Ma
    Citation: BMC Ophthalmology 2018 18:299
  37. We aimed to analyze the differences in the prevalence of outer retinal tubulation (ORT) in neovascular age-related macular degeneration (AMD) treated with anti-vascular endothelial growth factor (anti-VEGF) ag...

    Authors: Attila Kovacs, Timea Kiss, Ferenc Rarosi, Gabor M. Somfai, Andrea Facsko and Rozsa Degi
    Citation: BMC Ophthalmology 2018 18:298
  38. Genetic studies have reported contradictory results on the association between the intercellular adhesion molecule-1 (ICAM-1) rs5498 polymorphism and diabetic retinopathy (DR) risk in type 2 diabetic patients. We...

    Authors: Zikang Xie and Hao Liang
    Citation: BMC Ophthalmology 2018 18:297
  39. To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic ...

    Authors: Hong-Ying Jin, Ting Wan, Xiao-Ning Yu, Fang Wu and Ke Yao
    Citation: BMC Ophthalmology 2018 18:295
  40. Cataract surgery with pseudophakic mini-monovision has lower out-of-pocket patient expense than premium multifocal intraocular lenses (IOL). The purpose of this study was to evaluate patient-reported satisfact...

    Authors: Debora Goetz Goldberg, Michael H. Goldberg, Riddhi Shah, Jane N. Meagher and Haresh Ailani
    Citation: BMC Ophthalmology 2018 18:293

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