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  1. To identify novel biomarkers related to the pathogenesis of dry age-related macular degeneration (AMD), we adopted a human retinal pigment epithelial (RPE) cell culture model that mimics some features of dry A...

    Authors: Je-Hyun Baek, Daehan Lim, Kyu Hyung Park, Jae-Byoung Chae, Hyoik Jang, Jonghyun Lee and Hyewon Chung
    Citation: BMC Ophthalmology 2018 18:289
  2. To investigate thickness changes in the corneal epithelium and Bowman’s layer after overnight silicone hydrogel contact lens (CL) wear by using ultra-high resolution optical coherence tomography (UHROCT).

    Authors: Fan Lu, Aizhu Tao, Weiwei Tao, Xiran Zhuang and Meixiao Shen
    Citation: BMC Ophthalmology 2018 18:286
  3. The early diagnosis of cancer is of crucial importance and a key prognostic factor. Cancer-associated retinopathy (CAR) can be symptomatic prior to other manifestations directly related to malignant tumors. Th...

    Authors: Florence Hoogewoud, Pauline Butori, Philippe Blanche and Antoine P. Brézin
    Citation: BMC Ophthalmology 2018 18:285
  4. Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine g...

    Authors: Yasuhiro Iesato, Masaaki Tanaka, Masako Murata, Junya Kitahara, Takao Hirano, Taihei Kurenuma, Noriko Yoshida and Toshinori Murata
    Citation: BMC Ophthalmology 2018 18:284
  5. Giant cell arteritis (GCA) is a systemic vasculitis of medium and large-size vessels and can led to permanent visual loss in elderly patients. GCA is very rare among Asians. We report a Chinese patient present...

    Authors: Guohong Tian, Weimin Chen, Qian Chen, Min Wang, Guixian Zhao, Zhenxin Li and Jiong Zhang
    Citation: BMC Ophthalmology 2018 18:282
  6. A major obstacle that academic institutions face is the steep learning curve for cornea fellows initially learning to perform Descemet Stripping Endothelial Keratoplasty (DSEK). The purpose of this study is to...

    Authors: Jacquelyn Daubert, Terrence P. O’Brien, Eldad Adler and Oriel Spierer
    Citation: BMC Ophthalmology 2018 18:281
  7. Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat
    Citation: BMC Ophthalmology 2018 18:279
  8. Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especiall...

    Authors: Mário Luiz R. Monteiro, Kenzo Hokazono, Leonardo P. Cunha and Laurentino Biccas Neto
    Citation: BMC Ophthalmology 2018 18:278
  9. The present study reported a case of juxtapapillary retinal capillary hemangioma (JRCH) that was successfully treated by two sessions of full-fluence photodynamic treatment (PDT) with good visual outcome.

    Authors: Bainan Tong, Jun Xiao and Guanfang Su
    Citation: BMC Ophthalmology 2018 18:277
  10. Toxic anterior segment syndrome (TASS) can be a rare complication of anterior segment surgery. Here we reviewed the most recent advances in the understanding of TASS.

    Authors: Choul Yong Park, Jimmy K. Lee and Roy S. Chuck
    Citation: BMC Ophthalmology 2018 18:276
  11. The purpose of this study is to discuss whether genetic variants (rs2230199, rs1047286, rs2230205, and rs2250656) in the C3 gene account for a significant risk of advanced AMD.

    Authors: Jun Zhang, Shuang Li, Shuqiong Hu, Jiguo Yu and Yi Xiang
    Citation: BMC Ophthalmology 2018 18:274
  12. Shielding and scattering effect of the smoke plume column ejected from the laser ablated material is a well-known phenomenon. Debris evacuation system of the excimer laser equipment removes these particles, bu...

    Authors: Csaba Szekrényesi, Huba Kiss, Tamás Filkorn and Zoltán Zsolt Nagy
    Citation: BMC Ophthalmology 2018 18:273
  13. Giant retinal tear is usually challenging among retinal detachment with recurrent rate up to 45%. Here we presented a case of giant retinal tear being treated by microincision vitrectomy and retinal tacks fixa...

    Authors: Yo-Chen Chang, Li-Yi Chiu, Tzu-En Kao, Wen-Hsin Cheng, Ting-An Chen and Wen-Chuan Wu
    Citation: BMC Ophthalmology 2018 18:272
  14. The membrane frizzled-related protein (MFRP) gene is involved in axial length (AL) regulation and MFRP mutations cause nanophthalmos; also, the hepatocyte growth factor (HGF) gene is reported to result in morphol...

    Authors: Shaolin Wang, Wenjuan Zhuang, Jianqing Ma, Manyun Xu, Shunyu Piao, Juan Hao, Wen Zhang, Hao Chi, Zhongqi Xue and Shaoping Ha
    Citation: BMC Ophthalmology 2018 18:271
  15. The aim was, first, to collect normative data of the optic nerve head and the peripapillary retinal nerve fibre layer (RNFL) thickness assessed with Cirrus SD-OCT, in healthy children in a population-based stu...

    Authors: Eva Larsson, Anna Molnar and Gerd Holmström
    Citation: BMC Ophthalmology 2018 18:270
  16. To compare different K readings in pseudophakic patients post-Descemet’s stripping automated endothelial keratoplasty (DSAEK) and evaluate corresponding prediction errors in intraocular lens (IOL) power calculati...

    Authors: Ke Xu, Hong Qi, Rongmei Peng, Gege Xiao, Jing Hong, Yansheng Hao and Boping Ma
    Citation: BMC Ophthalmology 2018 18:268
  17. We report a rare case of a woman with optic disk melanocytoma (ODMC) in conjunction with polypoidal choroidal vasculopathy (PCV). We also present, for the first time in literature, the clinical and morphologic...

    Authors: Alexandros Rouvas, Nikolaos S Gouliopoulos, Marilita M Moschos and Panagiotis Theodossiadis
    Citation: BMC Ophthalmology 2018 18:267
  18. Waardenburg syndrome (WS) is a very rare genetic disorder affecting the neural crest cells. Coexistence of branch retinal vein occlusion (BRVO) and branch retinal artery occlusion (BRAO) in the same eye is als...

    Authors: Eun Young Choi, Wungrak Choi and Christopher Seungkyu Lee
    Citation: BMC Ophthalmology 2018 18:266
  19. To demonstrate a full thickness macular hole (MH) development after vitrectomy (VT) for rhegmatogenous retinal detachment (RRD) and to investigate the possible disease mechanism with optical coherence tomograp...

    Authors: Hsin-Yu Yang and Chang-Sue Yang
    Citation: BMC Ophthalmology 2018 18:265
  20. Coats disease is a retinal disease characterized by exudative retinal detachment due to abnormal retinal blood vessels. Coats disease is generally treated using laser photocoagulation and cryotherapy to ablate...

    Authors: Michie Namba, Yusuke Shiode, Yuki Morizane, Shuhei Kimura, Mio Hosokawa, Shinichiro Doi, Shinji Toshima, Kosuke Takahashi, Mika Hosogi, Atsushi Fujiwara and Fumio Shiraga
    Citation: BMC Ophthalmology 2018 18:264
  21. International Task Force (ITF) guidelines established a grading scheme to support treatment of dry eye disease based on clinical signs and symptoms. The purpose of this study was to assess the impact of dry ey...

    Authors: Laurie Barber, Omid Khodai, Thomas Croley, Christopher Lievens, Stephen Montaquila, Jillian Ziemanski, Melissa McCart, Orsolya Lunacsek, Caroline Burk and Vaishali Patel
    Citation: BMC Ophthalmology 2018 18:260
  22. We recently reported that lamellar macular hole (LMH) with lamellar hole-associated epiretinal proliferation (LHEP) can be effectively treated by embedding the LHEP into the retinal cleavage to improve foveal ...

    Authors: Yusuke Shiode, Yuki Morizane, Kosuke Takahashi, Shuhei Kimura, Mio Hosokawa, Masayuki Hirano, Shinichiro Doi, Shinji Toshima, Mika Hosogi, Atsushi Fujiwara and Fumio Shiraga
    Citation: BMC Ophthalmology 2018 18:257
  23. Descemet’s membrane detachment (DMD) is a rare complication after ocular chemical injury and its pathogenesis remains unclear. In this study, we reported two cases of DMD with traction demonstrated on Anterior...

    Authors: Xiaoling Zhang, Vishal Jhanji and Haoyu Chen
    Citation: BMC Ophthalmology 2018 18:256
  24. The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands.

    Authors: Cerys J. Evans, Lubica Dudakova, Pavlina Skalicka, Gabriela Mahelkova, Ales Horinek, Alison J. Hardcastle, Stephen J. Tuft and Petra Liskova
    Citation: BMC Ophthalmology 2018 18:250
  25. Attention is increasingly being given to microglia-related inflammation in neovascular diseases, such as diabetic retinopathy and age-related macular disease. Evidence shows that activated microglia contribute...

    Authors: Xinyi Ding, Ruiping Gu, Meng Zhang, Hui Ren, Qinmeng Shu, Gezhi Xu and Haixiang Wu
    Citation: BMC Ophthalmology 2018 18:249
  26. Neuromyelitis optica spectrum disorder-optic neuritis (NMOSD-ON) can now be distinguished from other types of ON as a specific disease by the Aquaporin-4 antibody (AQP4-Ab) test. NMOSD-ON can cause severe reti...

    Authors: Xiujuan Zhao, Wei Qiu, Yuxin Zhang, Yan Luo, Xiulan Zhang, Lin Lu and Hui Yang
    Citation: BMC Ophthalmology 2018 18:247
  27. Dense Deposit Disease is a rare condition affecting the Bruch’s membrane and the glomerular basement membrane. We report the progression of the ocular manifestations over a 30 year follow up period, longer tha...

    Authors: Alan Cunningham and Ajay Kotagiri
    Citation: BMC Ophthalmology 2018 18(Suppl 1):228

    This article is part of a Supplement: Volume 18 Supplement 1

  28. Primary vitreoretinal lymphoma (PVRL) is a rare ocular condition and its diagnosis remains a challenge. The clinical presentation is variable and it can masquerade as chronic intermediate or posterior uveitis....

    Authors: Shi Zhuan Tan, Laura R. Steeples, Ramandeep Chhabra and Nicholas P. Jones
    Citation: BMC Ophthalmology 2018 18(Suppl 1):223

    This article is part of a Supplement: Volume 18 Supplement 1

  29. The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk ...

    Authors: Gurjeet Jutley, Elizabeth Yang and Phillip Bloom
    Citation: BMC Ophthalmology 2018 18(Suppl 1):222

    This article is part of a Supplement: Volume 18 Supplement 1

  30. Retinal vascular occlusions are uncommon in young people and require more in-depth investigation into the cause. Studies have revealed that a high level of circulating homocysteine poses a risk for retinal vas...

    Authors: Clare Shute
    Citation: BMC Ophthalmology 2018 18(Suppl 1):220

    This article is part of a Supplement: Volume 18 Supplement 1

  31. This case highlights the important sequelae that can occur following the inadvertent implantation of a single-piece intraocular lens into the ciliary sulcus during cataract surgery; secondary pigment dispersio...

    Authors: Alastair Porteous and Laura Crawley
    Citation: BMC Ophthalmology 2018 18(Suppl 1):219

    This article is part of a Supplement: Volume 18 Supplement 1

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