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  1. To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world ...

    Authors: Polona Jaki Mekjavić, Bogdan Gregorčič, Cvetka Oberč and Slava Podgoršek
    Citation: BMC Ophthalmology 2018 18:333
    Content type: Research article Published on:

  2. The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR).

    Authors: Takao Hirano, Akira Imai, Hirotsugu Kasamatsu, Shinji Kakihara, Yuichi Toriyama and Toshinori Murata
    Citation: BMC Ophthalmology 2018 18:332
    Content type: Research article Published on:

  3. A substantial number of epidemiological studies have investigated the possible associations between sunlight exposure and Age-related Macular Degeneration (AMD), but the results from studies are inconsistent. ...

    Authors: Hongjie Zhou, Huina Zhang, Aiqing Yu and Jiajun Xie
    Citation: BMC Ophthalmology 2018 18:331
    Content type: Research article Published on:

  4. Orbital vascular malformation often encircles normal tissue with ill-defined borders. It is easy to bleed during resection operation, making surgical treatment difficult and lesions hard to be removed complete...

    Authors: Tingting Lin, Limin Zhu and Yanjin He
    Citation: BMC Ophthalmology 2018 18:330
    Content type: Research article Published on:

  5. To describe the effectiveness of combined pentagonal resection and inferior retractor plication (PR + IRP) based on the Hill’s procedure for the treatment of primary involutional lower eyelid entropion in the ...

    Authors: Janice J. C. Cheung, Carlos K. H. Wong and Leanne T. Y. Cheung
    Citation: BMC Ophthalmology 2018 18:329
    Content type: Research article Published on:

  6. Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogeni...

    Authors: Alexios J. Aletras, Ioannis Trilivas, Maria-Elpida Christopoulou, Sotiria Drakouli, Constantine D. Georgakopoulos and Nikolaos Pharmakakis
    Citation: BMC Ophthalmology 2018 18:328
    Content type: Research article Published on:

  8. To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA).

    Authors: Mengyang Li, Enzhong Jin, Chongya Dong, Chuan Zhang, Mingwei Zhao and Jinfeng Qu
    Citation: BMC Ophthalmology 2018 18:326
    Content type: Research article Published on:

  10. To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous n...

    Authors: Hiroto Terasaki, Shozo Sonoda, Naoko Kakiuchi, Hideki Shiihara, Takehiro Yamashita and Taiji Sakamoto
    Citation: BMC Ophthalmology 2018 18:324
    Content type: Research article Published on:

  11. Leber’s hereditary optic neuropathy (LHON) is a maternally inherited recessive disease rarely complicated with glaucoma. We conducted a clinical and genetic retrospective case series to describe three cases of...

    Authors: Yun-Hsuan Lin, Nan-Kai Wang, Ling Yeung, Chi-Chun Lai and Lan-Hsin Chuang
    Citation: BMC Ophthalmology 2018 18:323
    Content type: Case report Published on:

  12. This study aimed to investigate patient adherence to face-down positioning (FDP) and non-supine positioning (NSP) following vitrectomy with gas tamponade for treating macular holes (MHs).

    Authors: Emi Morimoto, Yoshiaki Shimada, Mitsuo Sugimoto, Tadashi Mizuguchi, Atsuhiro Tanikawa and Masayuki Horiguchi
    Citation: BMC Ophthalmology 2018 18:322
    Content type: Research article Published on:

  13. Changes in retinal fluid patterns associated with circumscribed choroidal hemangioma (CCH) have not been investigated yet. A long-term follow-up study was performed to evaluate the changes of retinal fluid pat...

    Authors: Junwon Lee, Christopher Seungkyu Lee, Min Kim and Sung Chul Lee
    Citation: BMC Ophthalmology 2018 18:321
    Content type: Research article Published on:

  14. To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma.

    Authors: Bradley H. Jacobsen, Christopher Ricks and Roger P. Harrie
    Citation: BMC Ophthalmology 2018 18:320
    Content type: Case report Published on:

    The Correspondence to this article has been published in BMC Ophthalmology 2019 19:193

  16. Doyne honeycomb retinal dystrophy (DHRD)/malattia leventinese (ML) is a rare allelic condition with massive drusen in the posterior fundus caused by EFEMP1 gene mutation. Patients showed decreased vision when the...

    Authors: Kaiyan Zhang, Xuyang Sun, Yingying Chen, Qionglei Zhong, Lin Lin, Yuan Gao and Fanlin Hong
    Citation: BMC Ophthalmology 2018 18:318
    Content type: Case report Published on:

  17. This report highlights a rare case of simultaneous bilateral blindness due to posterior ischemic optic neuropathy. Typically, ophthalmic involvement in giant cell arteritis is monocular or sequential ischemia ...

    Authors: Anas Mohammad Albarrak, Yousef Mohammad, Sajjad Hussain, Sufia Husain and Taim Muayqil
    Citation: BMC Ophthalmology 2018 18:317
    Content type: Case report Published on:

  18. Ingrowth of newly formed blood and lymph vessels (angiogenesis) from the limbus region into the cornea can be treated successfully by subconjunctival application of antiangiogenic agents. Currently, there are ...

    Authors: Patrick R. Merz, Nina Röckel, Seda Ballikaya, Gerd U. Auffarth and Ingo Schmack
    Citation: BMC Ophthalmology 2018 18:316
    Content type: Research article Published on:

  19. Despite the potential usefulness of optical coherence tomography angiography in retinal and optic disc conditions, the reliability of the imaging modality remains unclear. This study set out to measure the mic...

    Authors: Ching Wei Lim, Jun Cheng, Elton Lik Tong Tay, Hwei Yee Teo, Elizabeth Poh Ying Wong, Vernon Khet Yau Yong, Boon Ang Lim, Owen Kim Hee, Hon Tym Wong and Leonard Wei Leon Yip
    Citation: BMC Ophthalmology 2018 18:315
    Content type: Research article Published on:

  20. The purpose of this study is to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections to treat cytomegalovirus retinitis in patients without human immunodeficien...

    Authors: Zhuyun Qian, Haili Li, Yong Tao and Wensheng Li
    Citation: BMC Ophthalmology 2018 18:314
    Content type: Research article Published on:

  21. Patients with retinal diseases frequently complain of poor visual function even when visual acuity is relatively unaffected. This clinical finding has been attributed to deficits in contrast sensitivity (CS). ...

    Authors: Badr O. Alahmadi, Amro A. Omari, Maria Fernanda Abalem, Chris Andrews, Dana Schlegel, Kari H. Branham, Naheed W. Khan, Abigail Fahim and Thiran Jayasundera
    Citation: BMC Ophthalmology 2018 18:313
    Content type: Research article Published on:

  24. Cystoid macular oedema (CMO) is an uncommon complication associated with hydroxychloroquine (HCQ) retinopathy threatening central vision. We report a patient with HCQ retinopathy and CMO, for which an intravit...

    Authors: Seong Joon Ahn, Jooyoung Joung, Sang Hyup Lee and Byung Ro Lee
    Citation: BMC Ophthalmology 2018 18:310
    Content type: Case report Published on:

  25. The corneal epithelium is directly affected in dry eye syndrome. Thus, we attempted to describe the morphological features and evaluate the cellular density within the corneal epithelial layers in patients wit...

    Authors: Olivia L. Lee, Tudor C. Tepelus, Jianyan Huang, Anne G. Irvine, Christopher Irvine, Gloria B. Chiu and SriniVas R. Sadda
    Citation: BMC Ophthalmology 2018 18:309
    Content type: Research article Published on:

  26. Following publication of the original article [1], the authors notified us of that due to miscommunication during proofing their given names were not presented in their full form, but only using the initials.

    Authors: Seung Wan Nam, Dong Hui Lim, Kyu Yeon Cho, Hye Seung Kim, Kyunga Kim and Tae-Young Chung
    Citation: BMC Ophthalmology 2018 18:308
    Content type: Correction Published on:

    The original article was published in BMC Ophthalmology 2018 18:263

  27. Severe retinopathy of prematurity (ROP) with extremely unfavorable prognosis among infants can do great damage to individuals and bring tremendous social-economic burden. The purpose of this study is to descri...

    Authors: Guo-rui Dou, Man-hong Li, Zi-feng Zhang, Yi-na Lu, Yan-ni Zhu, Hai-yan Wang, Jing Wang, Xiao-jie Wang, Jing Fan and Yu-sheng Wang
    Citation: BMC Ophthalmology 2018 18:307
    Content type: Research article Published on:

  28. Although there are limited studies, recent data are lacking to accurately determine the magnitude of color blindness in Ethiopia and there is no evidence of such a study in Gish Abay town district. The purpose...

    Authors: Mengistu Zelalem Wale, Yekoye Abebe, Yilikal Adamu and Abebe Zelalem
    Citation: BMC Ophthalmology 2018 18:306
    Content type: Research article Published on:

  29. Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, review...

    Authors: Ahmet Murat Sarici, Burak Mergen, Velittin Oguz and Cezmi Dogan
    Citation: BMC Ophthalmology 2018 18:305
    Content type: Research article Published on:

  30. A rodent model of photodynamic AION resulting from intravenous verteporfin is presented. The analysis of the morphological function, the pathological changes and the potential mechanism of action were further ...

    Authors: Jing-yu Min, Yanan Lv, Lei Mao, Yuan-yuan Gong, Qing Gu and Fang Wei
    Citation: BMC Ophthalmology 2018 18:304
    Content type: Research article Published on:

  31. To investigate the concentrations of oxidative stress markers, 8-hydroxy-2′-deoxyquanosine (8-OHdG) and malondialdehyde (MDA), in tears and their correlation with the clinical activity score (CAS) in patients ...

    Authors: Won Choi, Ying Li, Yong Sok Ji and Kyung Chul Yoon
    Citation: BMC Ophthalmology 2018 18:303
    Content type: Research article Published on:

  33. Retinopathy of prematurity (ROP) is a vascular proliferative disorder of the developing retina and a significant cause of childhood blindness around the world. The incidence of ROP is affected by many factors,...

    Authors: Yunxia Leng, Wenzhi Huang, Guoliang Ren, Cheng Cai, Qingbiao Tan, Yuqin Liang, Weizhong Yang and Zongyin Gao
    Citation: BMC Ophthalmology 2018 18:301
    Content type: Research article Published on:

  34. The role of histone deacetylases 6 (HDAC6) has been elucidated in various neurodegenerative diseases. However, the effect of HDAC6 on retinal degenerative processes remains unknown. The aim of this study was t...

    Authors: Haihong Yuan, Hui Li, Ping Yu, Qichen Fan, Xuan Zhang, Wei Huang, Junyi Shen, Yongyao Cui and Wei Zhou
    Citation: BMC Ophthalmology 2018 18:300
    Content type: Research article Published on:

  35. Granulomatosis with polyangiitis (GPA), a necrotizing granulomatous disease, very rarely involves the central nervous system (CNS), particularly the pituitary. Delayed treatment may cause permanent bilateral b...

    Authors: Xia Zhang, Bing Xing, Hui You, Huanwen Wu, Yong Zhong and Jin Ma
    Citation: BMC Ophthalmology 2018 18:299
    Content type: Case report Published on:

  36. We aimed to analyze the differences in the prevalence of outer retinal tubulation (ORT) in neovascular age-related macular degeneration (AMD) treated with anti-vascular endothelial growth factor (anti-VEGF) ag...

    Authors: Attila Kovacs, Timea Kiss, Ferenc Rarosi, Gabor M. Somfai, Andrea Facsko and Rozsa Degi
    Citation: BMC Ophthalmology 2018 18:298
    Content type: Research article Published on:

  37. Genetic studies have reported contradictory results on the association between the intercellular adhesion molecule-1 (ICAM-1) rs5498 polymorphism and diabetic retinopathy (DR) risk in type 2 diabetic patients. We...

    Authors: Zikang Xie and Hao Liang
    Citation: BMC Ophthalmology 2018 18:297
    Content type: Research article Published on:

  39. To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic ...

    Authors: Hong-Ying Jin, Ting Wan, Xiao-Ning Yu, Fang Wu and Ke Yao
    Citation: BMC Ophthalmology 2018 18:295
    Content type: Research article Published on:

  41. Cataract surgery with pseudophakic mini-monovision has lower out-of-pocket patient expense than premium multifocal intraocular lenses (IOL). The purpose of this study was to evaluate patient-reported satisfact...

    Authors: Debora Goetz Goldberg, Michael H. Goldberg, Riddhi Shah, Jane N. Meagher and Haresh Ailani
    Citation: BMC Ophthalmology 2018 18:293
    Content type: Research article Published on:

  45. To identify novel biomarkers related to the pathogenesis of dry age-related macular degeneration (AMD), we adopted a human retinal pigment epithelial (RPE) cell culture model that mimics some features of dry A...

    Authors: Je-Hyun Baek, Daehan Lim, Kyu Hyung Park, Jae-Byoung Chae, Hyoik Jang, Jonghyun Lee and Hyewon Chung
    Citation: BMC Ophthalmology 2018 18:289
    Content type: Research article Published on:

  48. To investigate thickness changes in the corneal epithelium and Bowman’s layer after overnight silicone hydrogel contact lens (CL) wear by using ultra-high resolution optical coherence tomography (UHROCT).

    Authors: Fan Lu, Aizhu Tao, Weiwei Tao, Xiran Zhuang and Meixiao Shen
    Citation: BMC Ophthalmology 2018 18:286
    Content type: Research article Published on:

  49. The early diagnosis of cancer is of crucial importance and a key prognostic factor. Cancer-associated retinopathy (CAR) can be symptomatic prior to other manifestations directly related to malignant tumors. Th...

    Authors: Florence Hoogewoud, Pauline Butori, Philippe Blanche and Antoine P. Brézin
    Citation: BMC Ophthalmology 2018 18:285
    Content type: Research article Published on:

  50. Polypoidal choroidal vasculopathy (PCV) consists of polyps that potentially cause massive subretinal hemorrhage and their branching vascular network (BVN) of feeder vessels. Although conventional indocyanine g...

    Authors: Yasuhiro Iesato, Masaaki Tanaka, Masako Murata, Junya Kitahara, Takao Hirano, Taihei Kurenuma, Noriko Yoshida and Toshinori Murata
    Citation: BMC Ophthalmology 2018 18:284
    Content type: Case report Published on:
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