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  1. Endophthalmitis is a serious intraocular infection that frequently results in significant inflammation and vision loss. Because current therapeutics are often unsuccessful in mitigating damaging inflammation d...

    Authors: Phillip S. Coburn, Frederick C. Miller, Austin L. LaGrow, Salai Madhumathi Parkunan, C. Blake Randall, Rachel L. Staats and Michelle C. Callegan
    Citation: BMC Ophthalmology 2018 18:96
  2. Keratoconus (KC) is a multifactorial, degenerative ectatic condition of the cornea. It usually manifests during late adolescence or the early twenties. A painless disease, KC may end with severe visual loss. T...

    Authors: Yousef Shanti, Ithar Beshtawi, Sa’ed H. Zyoud, Ahlam Abu-Samra, Areen Abu-Qamar, Reem Barakat and Reham Shehada
    Citation: BMC Ophthalmology 2018 18:95
  3. This study is aimed to screen out the microRNAs (miRNAs) associated with H2O2 induced oxidative stress in human lens epithelial B3 (HLE-B3) cell lines and investigate their relations with the progression of age-r...

    Authors: Song Wang, Chenjun Guo, Mengsi Yu, Xiaona Ning, Bo Yan, Jing Zhao, Angang Yang and Hong Yan
    Citation: BMC Ophthalmology 2018 18:93
  4. Pellucid marginal corneal degeneration is a non-inflammatory disorder complicated by severe inferior corneal thinning. The central portion of the cornea, consequently, appears to protrude outwards, decreasing ...

    Authors: Andrew Winegarner, Yoshinori Oie and Kohji Nishida
    Citation: BMC Ophthalmology 2018 18:92
  5. The aim of this study was to evaluate the prevalence of diabetic macular edema (DME) utilizing optical coherence tomography (OCT), and to clarify the effects of the systemic findings and risk factors on the de...

    Authors: Durgul Acan, Mehmet Calan, Duygu Er, Tugba Arkan, Nilufer Kocak, Firat Bayraktar and Suleyman Kaynak
    Citation: BMC Ophthalmology 2018 18:91
  6. To report the results of multimodal imaging of a biochemically confirmed case of a family with gyrate atrophy (GA) associated with foveoschisis and macular pseudohole.

    Authors: Imène Zhioua Braham, Imen Ammous, Rim Maalej, Majdi Boukari, Ilhem Mili Boussen, Khalil Errais and Raja Zhioua
    Citation: BMC Ophthalmology 2018 18:89
  7. Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. Clostridium perfringens infection typically occurs after penetrating injury with soil-contaminated ...

    Authors: Ghita Guedira, Nabil Taright, Hélène Blin, Thameur Fattoum, Jordan Leroy, Youssef El Samad, Solange Milazzo and Farida Hamdad
    Citation: BMC Ophthalmology 2018 18:88
  8. Indocyanine Green Angiography (ICG-A) and Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography (EDI-OCT) are essential imaging techniques for diagnosis, management and understanding of the patho...

    Authors: Emilia Maggio, Alessandro Alfano, Antonio Polito and Grazia Pertile
    Citation: BMC Ophthalmology 2018 18:87
  9. Retinopathy of prematurity (ROP) refers to the developmental disorder of the retina in premature infants and is one of the most serious and most dangerous complications in premature infants. The prevalence of ...

    Authors: Milad Azami, Zahra Jaafari, Shoboo Rahmati, Afsar Dastjani Farahani and Gholamreza Badfar
    Citation: BMC Ophthalmology 2018 18:83
  10. Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the S...

    Authors: Masanori Fukumoto, Yui Nishida, Teruyo Kida, Takaki Sato, Takatoshi Kobayashi and Tsunehiko Ikeda
    Citation: BMC Ophthalmology 2018 18:82
  11. Epiretinal membranes (ERMs), secondary to retinal cell proliferation on the retinal surface, usually affect patients over 50 years of age but occur rarely in children. Here we report the case of a 4-year-old p...

    Authors: Wenyi Tang, Ruiping Gu, Ting Zhang and Gezhi Xu
    Citation: BMC Ophthalmology 2018 18:79
  12. The present study aimed to evaluate the degree of anterior capsule contraction (capsulorhexis contraction) with three different single-piece, hydrophilic acrylic intraocular lenses (IOLs).

    Authors: Mihyun Choi, Marjorie Z. Lazo, Minji Kang, Jeehye Lee and Choun-Ki Joo
    Citation: BMC Ophthalmology 2018 18:78
  13. Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) is a rare inflammatory eye disease that affects the Retinal Pigment Epithelium and outer retina. The purpose of this study was to describe its...

    Authors: Olivia Xerri, Sawsen Salah, Dominique Monnet and Antoine P. Brézin
    Citation: BMC Ophthalmology 2018 18:76
  14. Keratoconus typically presents in the teenage years and is more advanced in younger patients when compared with adults. In the present study, we aimed to assess the safety and efficacy of accelerated transepit...

    Authors: Mi Tian, Weijun Jian, Ling Sun, Yang Shen, Xiaoyu Zhang and Xingtao Zhou
    Citation: BMC Ophthalmology 2018 18:75
  15. Fuchs’ uveitis (FU) is occasionarlly complicated with heavy vitreous opacity. We have performed vitrectomy procedures to remove vitreous opacity in affected patients as part of differential diagnosis for prima...

    Authors: Hisae Nakahara, Toshikatsu Kaburaki, Rie Tanaka, Junko Matsuda, Mitsuko Takamoto, Kazuyoshi Ohtomo, Kimiko Okinaga, Keiko Komae, Jiro Numaga, Yujiro Fujino and Makoto Aihara
    Citation: BMC Ophthalmology 2018 18:74
  16. To evaluate monocular and binocular visual outcomes for near, intermediate, and far distance in patients implanted with diffractive multifocal intraocular lenses (IOLs) with different add power contralaterally.

    Authors: Chan Min Yang, Dong Hui Lim, Sungsoon Hwang, Joo Hyun and Tae-Young Chung
    Citation: BMC Ophthalmology 2018 18:73
  17. Membranoproliferative glomerulonephritis (MPGN) is characterized by mesangial cell proliferation and is classified into types I, II and III based on structural changes in the glomerular capillary walls. The dr...

    Authors: Masato Takei, Akira Obana, Takenori Inomata, Takao Tanaka, Tina Shiang, Yuan Bae, Tamiko Takemura and Akira Murakami
    Citation: BMC Ophthalmology 2018 18:72
  18. We developed a novel surgical technique to treat punctal stenosis involving the placement of three interrupted sutures after rectangular three-snip punctoplasty (TSP).

    Authors: Seong Jun Park, Ju Hee Noh, Ki Bum Park, Sun Young Jang and Jong Won Lee
    Citation: BMC Ophthalmology 2018 18:70
  19. More and more concerns have been arisen about the ability of new medical graduates to meet the demands of today’s practice environment. In this study, we wanted to develop a valid, reliable and standardized as...

    Authors: Zhihua Zhang, Minwen Zhou, Kun Liu, Bijun Zhu, Haiyun Liu, Xiaodong Sun and Xun Xu
    Citation: BMC Ophthalmology 2018 18:68
  20. To assess the retinal sensitivity in obstructive sleep apnea hypopnea syndrome (OSAHS) patients evaluated with standard automated perimetry (SAP). And to correlate the functional SAP results with structural pa...

    Authors: Paula Casas, Francisco J. Ascaso, Eugenio Vicente, Gloria Tejero-Garcés, María I. Adiego and José A. Cristóbal
    Citation: BMC Ophthalmology 2018 18:66
  21. Fungal keratitis is one of the major causes of visual impairment worldwide. However, the effectiveness of corneal collagen cross-linking (CXL) for fungal keratitis remains controversial. In this study, we deve...

    Authors: Ziqian Zhu, Hongmin Zhang, Juan Yue, Susu Liu, Zhijie Li and Liya Wang
    Citation: BMC Ophthalmology 2018 18:65
  22. To compare visual function and structural improvements in pseudophakic eyes with diabetic macular oedema (DMO) treated with the 0.19mg Fluocinolone Acetonide (FAc) intravitreal implant (IluvienTM) in a ‘real worl...

    Authors: William Fusi-Rubiano, Chandoshi Mukherjee, Mark Lane, Marie D. Tsaloumas, Nicholas Glover, Andrej Kidess, Alastair K. Denniston, Helen E. Palmer, Avinash Manna and Rupal Morjaria
    Citation: BMC Ophthalmology 2018 18:62
  23. Rhinosporidiosis is a rare chronic infection of the mucous membranes caused by the Rhinosporidium seeberi. Approximately 15% of cases of rhinosporidiosis are ocular, occurring mainly in the tarsal conjunctiva. Th...

    Authors: Elaine Fiod Costa, Luciano Moreira Pinto, Marcos Adriano Garcia Campos, Thais Mota Gomes and Gyl Eanes Barros Silva
    Citation: BMC Ophthalmology 2018 18:61
  24. To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM).

    Authors: André Rosentreter, Alexandra Lappas, Randolf Alexander Widder, Maged Alnawaiseh and Thomas Stefan Dietlein
    Citation: BMC Ophthalmology 2018 18:60
  25. To describe a retrospective study of macular retinoschisis that developed long after the onset of retinal artery occlusion (RAO) using optical coherence tomography (OCT).

    Authors: Norihiko Ishizaki, Teruyo Kida, Masanori Fukumoto, Takaki Sato, Hidehiro Oku and Tsunehiko Ikeda
    Citation: BMC Ophthalmology 2018 18:59
  26. P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that...

    Authors: Ming-Hui Zhao, Jianyan Hu, Shufeng Li, Qiang Wu and Peirong Lu
    Citation: BMC Ophthalmology 2018 18:58

    The Correction to this article has been published in BMC Ophthalmology 2019 19:64

  27. The pathophysiological changes occurring in the trabecular meshwork in primary open angle glaucoma are poorly understood, but are thought to include increased extracellular matrix deposition, trabecular meshwo...

    Authors: Esther L. Ashworth Briggs, Tze’Yo Toh, Rajaraman Eri, Alex W. Hewitt and Anthony L. Cook
    Citation: BMC Ophthalmology 2018 18:57
  28. Graves’ disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves’ Oph...

    Authors: Andrea Rau, Matthias Klopfer, Niklas Rommel, Mechthild Rau-Fornefeld and Andreas Kolk
    Citation: BMC Ophthalmology 2018 18:56
  29. Known causes of superficial punctuate keratopathy (SPK) in children include entropion, viral infection, blepharokeratoconjunctivitis (BKC), and toxicity of eye drops. However, there are some SPK patients whose...

    Authors: Ying-ying Gao, Hong-juan Wang and You Wu
    Citation: BMC Ophthalmology 2018 18:55
  30. In 2010, there were ~ 36 million migrant children under 18 y old in China. This study compared patterns of myopia prevalence and progression between migrant and resident children.

    Authors: Yingyan Ma, Senlin Lin, Jianfeng Zhu, Xun Xu, Lina Lu, Rong Zhao, Huijuan Zhao, Qiangqiang Li, Zhiyuan Hou, Xiangui He and Haidong Zou
    Citation: BMC Ophthalmology 2018 18:53

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