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  1. Retinal artery macroaneurysms (RAMs) are focal dilations of the large retinal arteries. Most RAMs are asymptomatic, however, when hemorrhage or exudation caused by a RAM involves the macula, patients can exper...

    Authors: Yang Meng, Yishuang Xu, Lu Li, Lu He, Zuohuizi Yi and Changzheng Chen
    Citation: BMC Ophthalmology 2022 22:461
    Content type: Case report Published on:

  2. Caffeinated beverages are very popular across populations and cultures, but quantitative evidence of the acute effects of moderate coffee doses on retinal perfusion is sparse and contradicting. Thus, the aim o...

    Authors: Xiaofeng Zhu, Jiong Zhu, Yongyi Wang, Zhongdi Chu, Ruikang K. Wang, Yi Xu, Lina Lu and Haidong Zou
    Citation: BMC Ophthalmology 2022 22:460
    Content type: Research Published on:

  3. Additive cosmetic implants (NewColorIris, Kahn Medical Devices, Panama City, Panama) are placed in the anterior chamber, in order to externally change iris color. There is a lack of robust clinical long-term p...

    Authors: Juan Queiruga-Piñeiro, Tomas Parra-Rodriguez and Ignacio Rodriguez-Una
    Citation: BMC Ophthalmology 2022 22:459
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Ophthalmology 2023 23:8

  5. Pathogenesis of posterior capsular opacification (PCO) was related to pathological epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs). It has been reported that blue light could have an ef...

    Authors: Dongyan Zhang, Hong Zhu, Xin Yu, Liyin Wang, Yingying Wen, Liyue Zhang, Jianping Tong and Ye Shen
    Citation: BMC Ophthalmology 2022 22:456
    Content type: Research Published on:

  6. Corneal neovascularization (CNV) is an important disease that causes blindness. Secretogranin III (Scg3) has emerged as a new influencing factor of neovascularization. This study analyzed the Scg3 antibody’s i...

    Authors: He Jin, Binbin Yang, Dongdong Jiang, Zhixiang Ding, Yu Xiong and Xinsheng Zeng
    Citation: BMC Ophthalmology 2022 22:455
    Content type: Research Published on:

  7. To evaluate the results of near confluent laser therapy versus combined less dense laser and intra vitreal bevacizumab in treatment of infants with type 1 retinopathy of prematurity (ROP) in zone II.

    Authors: Ehsan Namvar, Alireza Bolkheir, Zahra Emadi, Mohammadkarim Johari and Mohammad Hossein Nowroozzadeh
    Citation: BMC Ophthalmology 2022 22:454
    Content type: Research Published on:

  8. The goal of the research was to determine the incidence of microstructural alterations in the macula and optic nerve head (ONH) occurred in eyes treated with peripheral laser photocoagulation retinopexy.

    Authors: Mohammadkarim Johari, Salman Khani, Abdulrahim Amini and Alireza Bolkheir
    Citation: BMC Ophthalmology 2022 22:453
    Content type: Research Published on:

  9. Acute annular outer retinopathy (AAOR) is an uncommon disease. To date, there are few documented cases in the literature. Our case report is the first to describe a case of acute annular outer retinopathy in a...

    Authors: Rishi B. Gupta, Harry Dang, Danah Albreiki, Michael LE. Dollin, Bonnie Weston and Chloe C. Gottlieb
    Citation: BMC Ophthalmology 2022 22:452
    Content type: Case report Published on:

  10. Changes in the retina and choroid blood vessels are regularly observed in myopia. However, if the retinal glial cells, which directly contact blood vessels, play a role in mammalian myopia is unknown. We aimed...

    Authors: Xuhong Zhang, Xin Yu, Yingying Wen, Le Jin, Liyue Zhang, Hong Zhu, Dongyan Zhang, Chen Xie, Dongyu Guo, Jianping Tong and Ye Shen
    Citation: BMC Ophthalmology 2022 22:451
    Content type: Research Published on:

  12. There are some techniques for disassembly of hard nuclear. It is challenging in hard cataract surgery through microincision. The classic chop or prechop techniques often do not succeed,resulting in incomplete ...

    Authors: Mao Xu, Yongjun Qi, Yongde Weng, Yang Yang, Jianhua Deng, Wanjun Liu, Ting Mo and Xiangxiang Ye
    Citation: BMC Ophthalmology 2022 22:449
    Content type: Research Published on:

  13. Werner syndrome is a rare, autosomal recessive disorder characterised by premature aging. It is a typical hereditary progeroid syndrome that can be difficult to diagnose owing to its rarity and the similarity ...

    Authors: Tatsuya Nagai, Hirotaka Yokouchi, Gen Miura, Masaya Koshizaka, Yoshiro Maezawa, Toshiyuki Oshitari, Koutaro Yokote and Takayuki Baba
    Citation: BMC Ophthalmology 2022 22:448
    Content type: Case report Published on:

  14. This study provides a detailed description of a Chinese family with North Carolina macular dystrophy (NCMD) and explores its possible pathogenesis.

    Authors: Zhe Zhu, He Zou, Chuanyu Li, Bainan Tong, Chenchen Zhang and Jun Xiao
    Citation: BMC Ophthalmology 2022 22:447
    Content type: Research article Published on:

    The Matters Arising to this article has been published in BMC Ophthalmology 2023 23:370

  15. The aim of this study was to report the clinical profile and outcomes of retinal pigment epithelial detachment (PED) in Vogt-Koyanagi-Harada (VKH) disease, and to evaluate the correlation between PED and the s...

    Authors: Chuanzhen Zheng, Kaixuan Wang, Mi Zhang, Qingqin Tao, Xiaorong Li and Xiaomin Zhang
    Citation: BMC Ophthalmology 2022 22:446
    Content type: Research Published on:

  16. We would assess the efficacy of intravitreal injection of triamcinolone acetonide IVTA combined with standard phacoemulsification on the central subfield macular thickness (CSMT), the progression of diabetic r...

    Authors: Sarah Zaher Addeen and Iyad Shaddoud
    Citation: BMC Ophthalmology 2022 22:445
    Content type: Research Published on:

  17. Vitrectomy and peeling of the internal limiting membrane (ILM) was an effective therapeutic approach for myopic foveoschisis with progressive visual loss. This study investigated the anatomical and visual outc...

    Authors: Dezhi Zheng, Zijing Huang, Qin Zeng, Yifan Wang, Shirong Chen, Jingsheng Yi, Danqi Fang, Dingguo Huang and Weiqi Chen
    Citation: BMC Ophthalmology 2022 22:444
    Content type: Research Published on:

    The Matters Arising to this article has been published in BMC Ophthalmology 2023 23:272

  18. Childhood obesity was associated with retinochoroidal microvascular changes using optical coherence tomography angiography (OCTA), but obesity duration was neglected. Obesity is chronic and progressive and obe...

    Authors: Shu Han, Zhenhua Leng, Xiaoxiao Li, Wen Yan, Shiya Shen, Lei Liu, Hui Zhu, Dan Huang and Hu Liu
    Citation: BMC Ophthalmology 2022 22:443
    Content type: Research Published on:

  19. Herpes simplex keratitis (HSK) is a rare and sight-threatening complication following refractive surgery. SmartSurfACE surgery is the result of combining transepithelial photorefractive keratectomy (trans-PRK) wi...

    Authors: Ai-qin Nie, Xiao-min Chen and Qiang Li
    Citation: BMC Ophthalmology 2022 22:442
    Content type: Case report Published on:

  20. Usher syndrome (USH) is an autosomal recessive disorder primarily responsible for deaf-blindness. Patients with subtype Usher syndrome type 1 (USH1) typically experience congenital sensorineural hearing loss, ...

    Authors: Nelson Chen, Hane Lee, Angela H. Kim, Pei-Kang Liu, Eugene Yu-Chuan Kang, Yun-Ju Tseng, Go Hun Seo, Rin Khang, Laura Liu, Kuan-Jen Chen, We-Chi Wu, Meng-Chang Hsiao and Nan-Kai Wang
    Citation: BMC Ophthalmology 2022 22:441
    Content type: Case report Published on:

  21. Central Retinal Vein Occlusion (CRVO) is a rare complication of von Hipple-Lindau (VHL) disease. This report presents the first case of VHL disease complicated with CRVO caused by VHL c.208G > A mutation.

    Authors: Xingwang Chen, Mengyao Wang, Yuan Tang, Bing Xie, Xiaomei Nie and Shanjun Cai
    Citation: BMC Ophthalmology 2022 22:440
    Content type: Case report Published on:

  22. Recurrent retinal detachment (Re-RD) usually affects the prognosis of surgery for rhegmatogenous retinal detachment (RRD). Previous clinical studies of Re-RD were not specific. This study aimed to analyze the ...

    Authors: Jun-Xing Bai, Wei-Yu Zheng, Xiao-Qing Zhu and Xiao-Yan Peng
    Citation: BMC Ophthalmology 2022 22:439
    Content type: Research Published on:

  23. To evaluate the additive effects of orthokeratology (OK) lenses and 0.01% atropine on slowing axial elongation in myopic children.

    Authors: Shiao Yu, Liping Du, Na Ji, Binbin Li, Xuena Pang, Xiuhong li, Nana Ma, Congcong Huang and Aicun Fu
    Citation: BMC Ophthalmology 2022 22:438
    Content type: Research Published on:

  24. Autoimmune blistering skin diseases (AIBD) are a group of rare chronic autoimmune diseases which are associated with ocular surface diseases especially dry eye disease. This study is designed to investigate th...

    Authors: Huanmin Kang, Mengbo Wu, Jianing Feng, Yuerong Ren, Yingyi Liu, Wen Shi, Yingqian Peng, Yixin Tan, Ruifang Wu, Guiying Zhang and Yan He
    Citation: BMC Ophthalmology 2022 22:437
    Content type: Research Published on:

  25. To investigate the correlation between the clinical and pathological characteristics and outcomes in patients with eyelid malignant tumors underwent wide local excision.

    Authors: Yuanyuan Han, Miao Kong, Yan Luo, Bin Sun, Zhiqiang Wang and Hong Zhang
    Citation: BMC Ophthalmology 2022 22:436
    Content type: Research Published on:

  26. To determine the influence of implantable collamer lenses (ICL) geometry, i.e. spherical and toric on the vault, and report the refractive and visual outcomes of patients bilaterally implanted with the two ICL...

    Authors: Angel Sánchez Trancón, Santiago Cerpa Manito, Oscar Torrado Sierra, António Manuel Baptista and Pedro Miguel Serra
    Citation: BMC Ophthalmology 2022 22:435
    Content type: Research Published on:

  27. Hydroxychloroquine is a widely used medication for various clinical conditions mainly rheumatological and dermatological autoimmune diseases e.g. systemic lupus erythematosus, rheumatoid arthritis and psoriasi...

    Authors: Ahmed Ameen Ismail, Sherin Hassan Sadek and Ragai Magdy Hatata
    Citation: BMC Ophthalmology 2022 22:434
    Content type: Case report Published on:

  28. Rho-kinase inhibitors can inhibit fibrosis after glaucoma surgery. This study aimed to evaluate the effect of rho-kinase inhibitor after needling procedure with mitomycin C for the failure of filtering bleb wi...

    Authors: Yu Mizuno, Naoki Okada, Hiromitsu Onoe, Kana Tokumo, Hideaki Okumichi, Kazuyuki Hirooka and Yoshiaki Kiuchi
    Citation: BMC Ophthalmology 2022 22:433
    Content type: Research Published on:

  29. The developmental pathways and subsequent evolutional processes of idiopathic lamellar macular hole (LMH) were studied with spectrum domain optical coherence tomography (SD-OCT).

    Authors: Cheng-Yung Lee, Yun Hsia and Chung-May Yang
    Citation: BMC Ophthalmology 2022 22:432
    Content type: Research Published on:

    The Correction to this article has been published in BMC Ophthalmology 2022 22:488

  31. To assess whether informing patients with a computer-based tutorial in addition to standard informed consent influences the patient’s attitude towards surgery and increases patient’s knowledge.

    Authors: Marlies Ullrich, Oliver Findl, Katharina Kefer, Birgit Döller, Ralph Varsits, Julius Hienert and Nino Hirnschall
    Citation: BMC Ophthalmology 2022 22:430
    Content type: Research Published on:

  33. Intraocular lymphoma (IOL) is a masquerade syndrome that mimics uveitis, making diagnosis difficult. The serum soluble interleukin-2 receptor (sIL-2R), which is cleaved by matrix metalloproteinase (MMP) -2 and...

    Authors: Kayo Suzuki, Kenichi Namba, Satoru Kase, Yo Ogino, Keitaro Hase, Daiju Iwata, Kazuomi Mizuuchi, Miki Hiraoka, Nobuyoshi Kitaichi and Susumu Ishida
    Citation: BMC Ophthalmology 2022 22:428
    Content type: Research Published on:

  34. To investigate the possible association of different pattern of diabetic retinopathy (DR) on corneal endothelium cells in type 2 diabetes mellitus patients.

    Authors: Seyed-Ali-Akbar Mortazavi, Mohammadreza Akhlaghi, Alireza Dehghani, Mohsen Pourazizi, Mohammad Malekahmadi, Mohammadreza Fazel, Mehdi Tavakoli and Pegah Noorshargh
    Citation: BMC Ophthalmology 2022 22:427
    Content type: Research Published on:

  36. Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome is a bleeding disorder that can affect all parts of the body including the eyes. Different ocular abnormalities have been d...

    Authors: Ardiana Ala, Torben Lykke Sørensen and Caroline Schmidt Laugesen
    Citation: BMC Ophthalmology 2022 22:425
    Content type: Case report Published on:

  37. Posterior microphthalmos (PM) is a rare condition with poor visual prognosis even after amblyopia treatment. We report a case of PM with achievement of good visual acuity and disappearance of papillomacular re...

    Authors: Takako Hanyu, Satoshi Ueki, Yukari Hasegawa, Megumi Kiyokawa and Takeo Fukuchi
    Citation: BMC Ophthalmology 2022 22:424
    Content type: Case report Published on:

  39. To compare widefield swept-source optical coherence tomography angiography (SS-OCTA) with ultra-widefield fundus fluorescein angiography (UWF-FA) for detecting retinal vein occlusion (RVO) lesions.

    Authors: Li Siying, Zeng Qiaozhu, Han Xinyao, Zhang Linqi, Zhao Mingwei and Qu Jinfeng
    Citation: BMC Ophthalmology 2022 22:422
    Content type: Research Published on:

  40. To investigate the possible effect of implantable collamer lens (ICL) V4c on ocular biometric measurements by a new biometer Pentacam-AXL and partial coherence interferometry (PCI)-based IOLMaster 500 and intr...

    Authors: Di Zhang, Meng Yang, Ziyuan Liu, Hongyuan Cai, Xiaoyong Chen and Chun Zhang
    Citation: BMC Ophthalmology 2022 22:421
    Content type: Research Published on:

  41. Phacoemulsification has been the mainstay method for extracapsular cataract extraction surgery in the anterior segment; for cases of posterior drop of lens fragments into the vitreous, a posterior segment phac...

    Authors: Yu-Kuei Lee, Szu-Han Chen and Jia-Horung Hung
    Citation: BMC Ophthalmology 2022 22:420
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Ophthalmology 2022 22:467

  42. The purpose of this study is to study the effect of repeated intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs on vitreomacular interface.

    Authors: Fangyuan Han, Xingwang Chen, Ruyi Zhao, Xin Jin, Wei Tan and Ying Zhang
    Citation: BMC Ophthalmology 2022 22:419
    Content type: Research Published on:

  43. The aim of this study was to evaluate the structural retinal vascular integrity using optical coherence tomography angiography (OCTA) in treatment-naïve eyes with diabetic macular edema (DME) and to compare it...

    Authors: Imène Zhioua Braham, Hela Kaouel, Mejdi Boukari, Imen Ammous, Khalil Errais, Ilhem Mili Boussen and Raja Zhioua
    Citation: BMC Ophthalmology 2022 22:418
    Content type: Research Published on:

  46. Hemoglobin A1C (HbA1C) test is the best care evaluation measurement due to a strong correlation between the test results and diabetic complications. So, this cross-sectional study aimed to assess whether the leve...

    Authors: Javad Setareh, Ghazale Hoseinzade, Batoul Khoundabi, Mahsa Kamali, Ata Ebrahimi, Andarz Fazlollahpour-Naghibi, Mohammad Zareei, Mona Mohamaditabar and Ali Makaremi
    Citation: BMC Ophthalmology 2022 22:415
    Content type: Research Published on:

  47. Optical coherence tomography (OCT) angiography (OCTA) provides a quantitative assessment of the microcirculation of the retina and choroid. It may precede the retinal nerve layer (RNFL) and optic disc head def...

    Authors: Ayman Lotfy, Hala Kamal Mattout, Sameh Mosaad Fouda and Sahar Hemeda
    Citation: BMC Ophthalmology 2022 22:414
    Content type: Research Published on:

  48. To observe macular microvascular changes in patients with ischemic and non-ischemic central retinal vein occlusion (CRVO) by optical coherence tomography angiography (OCTA), and explore the value of OCTA in di...

    Authors: Weiting An, Qi Zhao, Rongguo Yu and Jindong Han
    Citation: BMC Ophthalmology 2022 22:413
    Content type: Research Published on:

  50. To evaluate anatomical and functional outcomes of patients with large submacular hemorrhage (SMH) who treated by pars plana vitrectomy (PPV) in combination with subretinal tissue plasminogen activator (TPA) in...

    Authors: Direk Patikulsila, Pawara Winaikosol, Janejit Choovuthayakorn, Nawat Watanachai, Voraporn Chaikitmongkol and Paradee Kunavisarut
    Citation: BMC Ophthalmology 2022 22:411
    Content type: Research Published on:
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