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  1. In Nigeria, glaucoma has a high prevalence and is the second cause of blindness among adults after cataract. People with glaucoma frequently present very late with advanced disease, and acceptance of and adher...

    Authors: Mohammed Mahdi Abdull, Clare Chandler and Clare Gilbert
    Citation: BMC Ophthalmology 2016 16:44
    Content type: Research article Published on:

  2. The aim of this study was to analyze the shifts in retinal vessel diameter and oxygen saturation in diabetic patients with and without diabetic retinopathy (DR), as well as to assess the association between di...

    Authors: Yanmin Dong, Leilei Lin, Hong Yan, Yue Fu, Yao Zong, Yongguang Yuan, Xia Huang, Yujie Li, Huining He and Qianying Gao
    Citation: BMC Ophthalmology 2016 16:43
    Content type: Research article Published on:

  3. Recently, novel anatomic parameters that can be measured by optical coherence tomography (OCT), have been identified as a more objective and accurate method of defining the iridocorneal angle. The aim of the p...

    Authors: José Ignacio Fernández-Vigo, Julián García-Feijóo, José María Martínez-de-la-Casa, Javier García-Bella, Pedro Arriola-Villalobos, Cristina Fernández-Pérez and José Ángel Fernández-Vigo
    Citation: BMC Ophthalmology 2016 16:42
    Content type: Research article Published on:

  4. Premacular subhyaloid hemorrhage results in a sudden profound loss of vision. Among the modalities for its treatment, Nd:YAG laser hyaloidotomy is a non invasive method enabling rapid drainage of the obstructe...

    Authors: Deepak Khadka, Sanjeeb Bhandari, Sanyam Bajimaya, Raba Thapa, Govinda Paudyal and Eli Pradhan
    Citation: BMC Ophthalmology 2016 16:41
    Content type: Research article Published on:

  5. The effect of obstructive sleep apnea (OSA) syndrome in the peripapillary retinal nerve fiber layer (RNFL) thicknesses remains unclear. The purpose of this study was to assess RNFL measurements acquired using ...

    Authors: Blanca Ferrandez, Antonio Ferreras, Pilar Calvo, Beatriz Abadia, Jose M. Marin and Ana B. Pajarin
    Citation: BMC Ophthalmology 2016 16:40
    Content type: Research article Published on:

  6. Vascular insufficiency has been reported to be a cause of normal tension glaucoma (NTG). The aim of this study was to compare ocular perfusion pressure (OPP) and ophthalmic artery flow (OAF) between patients w...

    Authors: Amir Samsudin, Nadine Isaacs, Mei-Ling Sharon Tai, Norlina Ramli, Zahari Mimiwati and May May Choo
    Citation: BMC Ophthalmology 2016 16:39
    Content type: Research article Published on:

  9. To determine the correlation between the optic nerve head (ONH) circulation determined by laser speckle flowgraphy and the best-corrected visual acuity or retinal sensitivity before and after intravitreal beva...

    Authors: Daisuke Nagasato, Yoshinori Mitamura, Kentaro Semba, Kei Akaiwa, Toshihiko Nagasawa, Yuki Yoshizumi, Hitoshi Tabuchi and Yoshiaki Kiuchi
    Citation: BMC Ophthalmology 2016 16:36
    Content type: Research article Published on:

  10. Descemet membrane detachment (DMD) is a significant complication noted during or early after cataract surgery. Review of literature revealed a few cases of delayed-onset DMD with presentation ranging from week...

    Authors: Harsimran Kaur Bhatia and Rakesh Gupta
    Citation: BMC Ophthalmology 2016 16:35
    Content type: Case report Published on:

  11. The purpose of this study was to evaluate the results of tarsoaponeurectomy in patients with unsuccessful results after repetitive surgery or who developed post-traumatic blepharoptosis.

    Authors: Selam Yekta Sendul, Burcu Dirim, Mehmet Demir, Zeynep Acar, Atilla Gokce Demir, Ali Olgun, Semra Tiryaki, Cemile Ucgul and Dilek Guven
    Citation: BMC Ophthalmology 2016 16:34
    Content type: Research article Published on:

  13. The purpose of this study was to report case series of retinal artery occlusion (RAO) as one of the significant complication post cardiac intervention.

    Authors: Yong Meng Hsien, Mushawiahti Mustapha, Jemaima Che Hamzah, Oteh Maskon, Choor Chee Ken and Che Hassan Hamat Hamdi
    Citation: BMC Ophthalmology 2016 16:32
    Content type: Case report Published on:

  14. With increasing experience using anti-VEGF therapy for the treatment of neovascular age-related macular degeneration (nAMD), ophthalmologists have shifted away from a “one size fits all” to an “individualised”...

    Authors: Jennifer J. Arnold, Caroline M. Markey, Nicol P. Kurstjens and Robyn H. Guymer
    Citation: BMC Ophthalmology 2016 16:31
    Content type: Study protocol Published on:

  16. Wavefront-guided Laser-assisted in situ keratomileusis (LASIK) is a widespread and effective surgical treatment for myopia and astigmatic correction but whether it induces higher-order aberrations remains cont...

    Authors: Ferial M. Al-Zeraid and Uchechukwu L. Osuagwu
    Citation: BMC Ophthalmology 2016 16:29
    Content type: Research article Published on:

  17. Diabetes is an increasing public health problem in the UK and globally. Diabetic retinopathy is a microvascular complication of diabetes, and is one of the leading causes of blindness in the UK working age pop...

    Authors: Gaby Judah, Ivo Vlaev, Laura Gunn, Dominic King, Derek King, Jonathan Valabhji, Ara Darzi and Colin Bicknell
    Citation: BMC Ophthalmology 2016 16:28
    Content type: Study protocol Published on:

  18. Controlling retinoblastoma with seeding is challenging despite advances in treatment modalities. Intravitreal melphalan is an alternative to external beam radiation or enucleation for recurrent or refractory v...

    Authors: An- Ning Chao, Ling-Yuh Kao, Laura Liu and Nan-Kai Wang
    Citation: BMC Ophthalmology 2016 16:27
    Content type: Case report Published on:

  19. Differences in the increase in matrix metalloproteinase (MMP) and decrease in tissue inhibitor of metalloproteinase (TIMP) activity may contribute to the different characteristics observed clinically on decrea...

    Authors: Hiroshi Yamada, Masahiko Yoneda, Masahiko Gosho, Tomohiro Kato and Masahiro Zako
    Citation: BMC Ophthalmology 2016 16:26
    Content type: Research article Published on:

  20. The purpose of this study was to investigate peripapillary choroidal thickness (CT) in eyes with neovascular age-related macular degeneration (AMD) and to assess whether peripapillary CT is affected by intravi...

    Authors: Cheolmin Yun, Jaeryung Oh, Kwang-Eon Choi, Soon-Young Hwang, Seong-Woo Kim and Kuhl Huh
    Citation: BMC Ophthalmology 2016 16:25
    Content type: Research article Published on:

  21. Clinical studies comparing trabeculectomy augmented with Ologen implant (OLO) versus trabeculectomy plus mitomycin-C (MMC) show contradictory results. To obtain long-term data, we report an extended 5-year fol...

    Authors: Salvatore Cillino, Alessandra Casuccio, Francesco Di Pace, Carlo Cagini, Lucia Lee Ferraro and Giovanni Cillino
    Citation: BMC Ophthalmology 2016 16:24
    Content type: Research article Published on:

  22. It is generally accepted that dialysis may lower plasma osmolality at a faster rate than changes in ocular osmolality. This osmotic difference causes water to migrate from the plasma into the aqueous humor, in...

    Authors: P. Frezzotti, C. Menicacci, S. A. Bagaglia, P. Mittica, F. Toto and I. Motolese
    Citation: BMC Ophthalmology 2016 16:23
    Content type: Case report Published on:

  24. Anomalous head posture (AHP) or torticollis is a relatively common condition in children. Torticollis is not a diagnosis, but it is a sign of underlying disease. Grisel’s syndrome (GS) is a rare condition of u...

    Authors: Davide Allegrini, Alessandro Autelitano, Elisabetta Nocerino, Paolo Fogagnolo, Stefano De Cillà and Luca Rossetti
    Citation: BMC Ophthalmology 2016 16:21
    Content type: Case report Published on:

  25. To protect from erosion of the tube in glaucoma drainage device (GDD), the tube is covered by a biologic tissue which is roofed by the conjunctiva. Sclera, pericardium, dura mater and cornea are available as a...

    Authors: Oriel Spierer, Michael Waisbourd, Yitzhak Golan, Hadas Newman and Rony Rachmiel
    Citation: BMC Ophthalmology 2016 16:20
    Content type: Research article Published on:

  26. Increased serum levels of angiotensin converting enzyme and lysozyme are considered as inflammatory markers for diagnosis of sarcoidosis which is an autoimmune inflammatory disease. The purpose of this study i...

    Authors: Ozlem Sahin, Alireza Ziaei, Eda Karaismailoğlu and Nusret Taheri
    Citation: BMC Ophthalmology 2016 16:19
    Content type: Research article Published on:

  27. Foveal detachment associated with foveoschisis usually takes a progressive course, and is associated with a poor visual outcome. The purpose of this study was to report the spontaneous resolution of foveal det...

    Authors: Tso-Ting Lai, Tzyy-Chang Ho and Chung-May Yang
    Citation: BMC Ophthalmology 2016 16:18
    Content type: Research article Published on:

  29. The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty, because the quality of donor corneal endothelial cel...

    Authors: Xiaowen Zhao, Ye Wang, Yao Wang, Suxia Li and Peng Chen
    Citation: BMC Ophthalmology 2016 16:16
    Content type: Research article Published on:

  30. It is known that office-hour measurements might not adequately estimate IOP mean, peaks and fluctuations in healthy subjects. The purpose of the present study is to verify whether office-hour measurements in p...

    Authors: Leonardo Colombo, Paolo Fogagnolo, Giovanni Montesano, Stefano De Cillà, Nicola Orzalesi and Luca Rossetti
    Citation: BMC Ophthalmology 2016 16:15
    Content type: Research article Published on:

  32. Stargardt’s disease (STGD) and Retinitis Pigmentosa (RP) are inherited retinal degenerations that may be affected, in opposite way, by diet.

    Authors: Francesco Sofi, Andrea Sodi, Fabrizio Franco, Vittoria Murro, Dania Biagini, Alba Miele, Giacomo Abbruzzese, Dario Pasquale Mucciolo, Gianni Virgili, Ugo Menchini, Alessandro Casini and Stanislao Rizzo
    Citation: BMC Ophthalmology 2016 16:13
    Content type: Research article Published on:

  34. Drug discovery has undergone major transformations in the last century, progressing from the recognition and refinement of natural products with therapeutic benefit, to the systematic screening of molecular li...

    Authors: Nicholas J. D. Gower, Robert J. Barry, Matthew R. Edmunds, Lucy C. Titcomb and Alastair K. Denniston
    Citation: BMC Ophthalmology 2016 16:11
    Content type: Debate Published on:

  35. Rhino-orbito-cerebral mucormycosis(ROCM) is an invasive fungal infection that usually occurs in immunocompromised patients and sometimes presents as orbital apex syndrome(OAS) initially. It is rapidly fatal wi...

    Authors: Nan Jiang, Guiqiu Zhao, Shanshan Yang, Jing Lin, Liting Hu, Chengye Che, Qian Wang and Qiang Xu
    Citation: BMC Ophthalmology 2016 16:10
    Content type: Research article Published on:

  37. Angiomyolipoma is a benign mesenchymal tumor composed of variable amounts of smooth muscle, adipose tissue and thick-walled blood vessels, and usually named PEComas (perivascular epithelioid cell tumors). PECo...

    Authors: Che-Yu Lin, Chieh-Chih Tsai, Hui-Chuan Kau, Wei-Kuang Yu, Shu-Ching Kao and Catherine Jui-Ling Liu
    Citation: BMC Ophthalmology 2016 16:8
    Content type: Case report Published on:

  38. Neovascular glaucoma is a refractive glaucoma. Recently, anti-VEGF factors have been used alone or in combination for the treatment of neovascular glaucoma. However, the medium- and long-term efficacy of such ...

    Authors: Min Tang, Yang Fu, Ying Wang, Zhi Zheng, Ying Fan, Xiaodong Sun and Xun Xu
    Citation: BMC Ophthalmology 2016 16:7
    Content type: Research article Published on:

  39. The existing literature contains no information regarding inflammatory cytokine expression in unilateral acute primary angle-closure (APAC) affected eyes and fellow eyes with primary angle closure suspect (PAC...

    Authors: Shaolin Du, Wenbin Huang, Xiulan Zhang, Jiawei Wang, Wei Wang and Dennis S. C. Lam
    Citation: BMC Ophthalmology 2016 16:6
    Content type: Research article Published on:

  42. Fluocinolone acetonide slow release implant (Iluvien®) was approved in December 2013 in UK for treatment of eyes which are pseudophakic with DMO that is unresponsive to other available therapies. This approval...

    Authors: Ibrahim Elaraoud, Walter Andreatta, Andrej Kidess, Ajay Bhatnagar, Marie Tsaloumas, Fahad Quhill and Yit Yang
    Citation: BMC Ophthalmology 2016 16:3
    Content type: Research article Published on:

  43. Glaucoma combined with an extremely shallow anterior chamber and cataracts remains as a complex condition to deal with. And the emergence of microincision vitrectomy surgery (MIVS) system may provide an ideal ...

    Authors: Zhaotian Zhang, Shaochong Zhang, Xintong Jiang, Suo Qiu and Yantao Wei
    Citation: BMC Ophthalmology 2016 16:2
    Content type: Research article Published on:

  44. To evaluate the ocular pulse amplitude (OPA), the posterior pole asymmetry analysis (PPAA), the peripapillary retinal nerve fiber layer (RNFL) thickness, the ganglion cell layer (GCL) thickness, macular thickn...

    Authors: Semra Acer, Attila Oğuzhanoğlu, Ebru Nevin Çetin, Nedim Ongun, Gökhan Pekel, Alper Kaşıkçı and Ramazan Yağcı
    Citation: BMC Ophthalmology 2016 16:1
    Content type: Research article Published on:

  45. Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are among the leading causes of visual impairment and blindness in developing countries. This study aims to explore the awareness of these r...

    Authors: Raba Thapa, Sanyam Bajimaya, Govinda Paudyal, Shankar Khanal, Stevie Tan, Suman S. Thapa and Ger van Rens
    Citation: BMC Ophthalmology 2015 15:188
    Content type: Research article Published on:

  46. Matrix metalloproteinases (MMPs), a family of Zn2+-dependent endoproteases, have been shown to act as fine regulators of both health and disease. Limited research revealed that they are essential to maintaining o...

    Authors: Lies De Groef, Lien Andries, Kim Lemmens, Inge Van Hove and Lieve Moons
    Citation: BMC Ophthalmology 2015 15:187
    Content type: Research article Published on:

  47. The aim of this study was to investigate the potential significance of the central macular thickness (foveal thickness-FT) and choroidal thickness (CT) in the eyes of patients with iron-deficiency anemia, the ...

    Authors: Erhan Yumusak, Aydin Ciftci, Selim Yalcin, Cemile Dayangan Sayan, Nevin Hande Dikel and Kemal Ornek
    Citation: BMC Ophthalmology 2015 15:186
    Content type: Research article Published on:

  48. Glaucoma is an optic neuropathy characterized by retinal ganglion cells (RGC) loss and retinal nerve fiber layer (RNFL) injury: this results in functional and morphological changes. The first can be observed b...

    Authors: Pietro Distante, Sara Lombardo, Alice Chandra Verticchio Vercellin, Marta Raimondi, Massimiliano Rolando, Carmine Tinelli and Giovanni Milano
    Citation: BMC Ophthalmology 2015 15:185
    Content type: Research article Published on:

  50. Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of...

    Authors: Emilia Maggio, Antonio Polito, Maria C. Freno and Grazia Pertile
    Citation: BMC Ophthalmology 2015 15:183
    Content type: Case report Published on:
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