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  1. Diabetic macular edema (DME) with neurosensory retinal detachment (NSD) remains an important cause of visual loss in patients with diabetes. The aim of the study was to elucidate the association of systemic an...

    Authors: Aditi Gupta, Rajiv Raman, Vaitheeswaran Kulothungan and Tarun Sharma
    Citation: BMC Ophthalmology 2014 14:47
  2. Ocular rhinosporidiosis is a chronic granulomatous infection caused by a newly classified organism that is neither a fungus nor bacterium. It often presents as a benign conjunctival tumour but may mimic other ...

    Authors: Stephen Gichuhi, Timothy Onyuma, Ephantus Macharia, Joy Kabiru, Alain M’bongo Zindamoyen, Mandeep S Sagoo and Matthew J Burton
    Citation: BMC Ophthalmology 2014 14:45
  3. State level information regarding eye care resources can provide policy makers with valuable information about availability of eye care services. The current study surveyed ophthalmologists, optometrists and v...

    Authors: Paul A MacLennan, Gerald McGwin Jr, Karen Searcey and Cynthia Owsley
    Citation: BMC Ophthalmology 2014 14:44
  4. The baseline data pertaining to the national epidemiological survey of infectious keratitis remain scarce in China, and currently there is no corneal blindness control strategy developed by the nation.

    Authors: Jin Cao, Yanning Yang, Wanju Yang, Ruoxi Wu, Xuan Xiao, Jing Yuan, Yiqiao Xing and Xiaodong Tan
    Citation: BMC Ophthalmology 2014 14:43
  5. To examine the all-cause mortality and uveal melanoma specific mortality among newly diagnosed uveal melanoma patients after five years. Furthermore, we assess of the effect of iris colour and having children ...

    Authors: Andrea Schmidt-Pokrzywniak, Sven Kalbitz, Oliver Kuss, Karl-Heinz Jöckel, Norbert Bornfeld and Andreas Stang
    Citation: BMC Ophthalmology 2014 14:42
  6. Many efforts have been invested in slowing progression of myopia. Among the methods, atropine administration and orthokeratology (OK) are most widely used. This study analyzed the efficacy of atropine and OK l...

    Authors: Hui-Ju Lin, Lei Wan, Fuu-Jen Tsai, Yi-Yu Tsai, Liuh-An Chen, Alicia Lishin Tsai and Yu-Chuen Huang
    Citation: BMC Ophthalmology 2014 14:40
  7. Though a newly developed spectral domain optical coherence tomography (OCT) is at the center of interests for many ophthalmologic researchers and clinicians, its own characteristics are not fully evaluated yet...

    Authors: Samin Hong, Sang-Myung Kim, Kyoungsoo Park, Jun Mo Lee, Chan Yun Kim and Gong Je Seong
    Citation: BMC Ophthalmology 2014 14:38
  8. The exact pathogenetic mechanisms of Coats’ disease remain unknown. In this report, we show two cases of Coats’ disease that achieved a favorable prognosis with the combined treatment of intravitreal bevacizum...

    Authors: Aya Kodama, Koji Sugioka, Shunji Kusaka, Chota Matsumoto and Yoshikazu Shimomura
    Citation: BMC Ophthalmology 2014 14:36
  9. The aim of this retrospective study is a long-term evaluation of postoperative motor outcomes and the inferential analysis of strabismus surgery in infant eyes with essential infantile esotropia.

    Authors: Adriano Magli, Roberta Carelli, Francesco Matarazzo and Dario Bruzzese
    Citation: BMC Ophthalmology 2014 14:35
  10. A wide range of organisms that enter the eye following ocular trauma can cause endophthalmitis. This study was to investigate the spectrum of pathogens and antibiotic susceptibility of bacterial isolates from ...

    Authors: Chongde Long, Bingqian Liu, Chaochao Xu, Yuan Jing, Zhaohui Yuan and Xiaofeng Lin
    Citation: BMC Ophthalmology 2014 14:34
  11. Altered levels of specific matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in the aqueous humour of primary open-angle glaucoma (POAG) eyes have been described. In this stu...

    Authors: Angeline DC Nga, Soon-Lek Yap, Amir Samsudin, Puteri S Abdul-Rahman, Onn H Hashim and Zahari Mimiwati
    Citation: BMC Ophthalmology 2014 14:33
  12. Improving adherence to ocular hypertension (OH)/glaucoma therapy is highly likely to prevent or reduce progression of optic nerve damage. The present study used a behaviour change counselling intervention to d...

    Authors: Heidi Cate, Debi Bhattacharya, Allan Clark, Richard Fordham, Richard Holland and David C Broadway
    Citation: BMC Ophthalmology 2014 14:32
  13. To present our findings in a case of Werner syndrome with refractory cystoid macular edema (CME) and to determine the expression and the distribution of WRN proteins in human retinas.

    Authors: Toshiyuki Oshitari, Masayasu Kitahashi, Satoshi Mizuno, Takayuki Baba, Mariko Kubota-Taniai, Minoru Takemoto, Koutaro Yokote, Shuichi Yamamoto and Sayon Roy
    Citation: BMC Ophthalmology 2014 14:31
  14. To evaluate the clinical utility of spectral analysis of intraocular pressure pulse wave in healthy eyes of a control group (CG), patients having glaucomatous optic disc appearance or ocular hypertension, and ...

    Authors: Magdalena Asejczyk-Widlicka, Patrycja Krzyżanowska-Berkowska, Małgorzata Kowalska and D Robert Iskander
    Citation: BMC Ophthalmology 2014 14:30
  15. The goal of this study was to investigate the visual outcome of acute central retinal artery occlusion (CRAO) after current standard therapy with and without paracentesis. In addition, we investigated whether ...

    Authors: Achim Fieß, Ömer Cal, Stephan Kehrein, Sven Halstenberg, Inez Frisch and Ulrich Helmut Steinhorst
    Citation: BMC Ophthalmology 2014 14:28
  16. To explore the intraocular pressure-lowering effect and complications of diode laser transscleral cyclophotocoagulation (DLTSC) followed by phacotrabeculectomy on medically unresponsive acute primary angle clo...

    Authors: Wei Liu, Yanhui Chen, Yingjuan Lv, Linni Wang, Xiaoli Xing, Aihua Liu and Jian Ji
    Citation: BMC Ophthalmology 2014 14:26
  17. There is a huge need for the availability of transplantable donor corneas worldwide to reduce the burden of corneal blindness due to corneal opacity. Voluntary eye donation depends on the awareness levels of v...

    Authors: Venkata Ramana Ronanki, Sethu Sheeladevi, Brinda P Ramachandran and Isabelle Jalbert
    Citation: BMC Ophthalmology 2014 14:25
  18. Blank cartridge guns are generally regarded as being harmless and relative safe. However recent published articles demonstrated that the gas pressure from the exploding propellant of blank cartridge is powerfu...

    Authors: Sunghyuk Moon and Su-Ho Lim
    Citation: BMC Ophthalmology 2014 14:23
  19. Dysregulation of the CCR3/CCL11 pathway has been implicated in the pathogenesis of choroidal neovascularisation, a common feature of late age-related macular degeneration (AMD). The aim of this study was to in...

    Authors: Mads Krüger Falk, Amardeep Singh, Carsten Faber, Mogens Holst Nissen, Thomas Hviid and Torben Lykke Sørensen
    Citation: BMC Ophthalmology 2014 14:22
  20. To report the clinical outcomes in Chinese patients with primary open-angle glaucoma and ocular hypertension treated with bimatoprost 0.03% therapy.

    Authors: Kaidi Wang, Li Xu, Zhilan Yuan, Ke Yao, Junmei Zhao, Liang Xu, Aiwu Fang, Mingzhi Zhang, Lingling Wu, Jian Ji, Jiamin Hou, Qing Liu and Xinghuai Sun
    Citation: BMC Ophthalmology 2014 14:21
  21. Diabetic retinopathy (DR) is the most common microvascular complication of diabetes. It can lead to significant visual loss. The aim of this study was to determine the frequency and clinical profile of diabeti...

    Authors: Ahmadou M Jingi, Jean Jacques N Noubiap, Augustin Ellong, Jean Joel R Bigna and Côme Ebana Mvogo
    Citation: BMC Ophthalmology 2014 14:19
  22. We present a case of a macular hole formation and its spontaneous closure after vitrectomy for vitreomacular traction. To our knowledge, it is the first description of spontaneous closure of the macular hole a...

    Authors: Dominik Odrobina, Iwona Laudańska-Olszewska, Piotr Gozdek, Mariusz Maroszyński and Michael Amon
    Citation: BMC Ophthalmology 2014 14:17
  23. To report the rate of cystoid macular oedema (CMO) as detected by spectral-domain optical coherence tomography (SD-OCT) after intraoperative complication during phacoemulsification. The secondary objectives in...

    Authors: Keat Ween Khaw, Hee Hong Lam, Tsung Fei Khang, Azida Juana Wan Ab Kadir and Visvaraja Subrayan
    Citation: BMC Ophthalmology 2014 14:16
  24. The editors of BMC Ophthalmology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).

    Authors: Alice K Murray
    Citation: BMC Ophthalmology 2014 14:14
  25. Graves’ disease (GD) and Graves’ ophthalmopathy (GO) are autoimmune disorders, which might be influenced by genetic factors. Copy number variation (CNV) is an important source of genomic diversity in humans, a...

    Authors: Wen-Ling Liao, Lei Wan, Tzu-Yuan Wang, Ching-Chu Chen, Siu-San Tse, Chieh-Hsiang Lu and Fuu-Jen Tsai
    Citation: BMC Ophthalmology 2014 14:15
  26. The treatment of uveal melanoma has seen a shift towards eye conserving treatments. Efforts have been made towards the identification of patients at high risk of metastatic disease with the use of prognostic f...

    Authors: Li-Anne Lim, Cristina Miyamoto, Paula Blanco, Silvin Bakalian and Miguel N Burnier Jr
    Citation: BMC Ophthalmology 2014 14:13
  27. To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure.

    Authors: Aachal Kotecha, Richard A Russell, Angelos Sinapis, Sayeh Pourjavan, Dimitros Sinapis and David F Garway-Heath
    Citation: BMC Ophthalmology 2014 14:11
  28. Prior studies have shown age-related macular degeneration (AMD) to be associated with falls. The purpose of this study is to determine if (AMD) and AMD-related vision loss are associated with fear of falling, ...

    Authors: Suzanne W van Landingham, Robert W Massof, Emilie Chan, David S Friedman and Pradeep Y Ramulu
    Citation: BMC Ophthalmology 2014 14:10
  29. Presbyopia is the age-related decline in accommodation that diminishes the ability of the eye to focus on near objects. Presbyopia is common and easy to correct; however, many communities lack access to basic ...

    Authors: Thomas J Wubben, Christopher M Guerrero, Marlo Salum, Gregory S Wolfe, Gerald P Giovannelli and David J Ramsey
    Citation: BMC Ophthalmology 2014 14:9
  30. A new procedure to correct myopia that does not disturb the cornea in the optical zone and avoids injuring the corneal epithelium could be a key advance in corneal refractive surgery. The aim of this study is ...

    Authors: Zhen-Yong Zhang, Matthew R Hoffman, Xing-Tao Zhou, Ye Xu, Xing-Ru Zhang, Ren-Yuan Chu and Chong-Da Chen
    Citation: BMC Ophthalmology 2014 14:8
  31. Macular oedema secondary to retinal vein occlusion (RVO) can cause vision loss due to blockage of the central retinal vein (CRVO) or a branch retinal vein (BRVO). This systematic review assessed the efficacies...

    Authors: Julie Glanville, Jacoby Patterson, Rachael McCool, Alberto Ferreira, Kerry Gairy and Ian Pearce
    Citation: BMC Ophthalmology 2014 14:7
  32. To report two cases of Descemet Membrane Endothelial Keratoplasty (DMEK) in patients with existing scleral-fixated and iris-fixated intraocular lenses (sf-IOL and if-IOL, respectively).

    Authors: Daniel Röck, Tobias Röck, Karl-Ulrich Bartz-Schmidt and Efdal Yoeruek
    Citation: BMC Ophthalmology 2014 14:6
  33. Specific cross-reacting autoimmunity against recoverin or collapsin response mediator protein (CRMP)-5 is known to cause cancer-associated retinopathy or paraneoplastic optic neuropathy, respectively. We repor...

    Authors: Michiyuki Saito, Wataru Saito, Atsuhiro Kanda, Hiroshi Ohguro and Susumu Ishida
    Citation: BMC Ophthalmology 2014 14:5
  34. The cataract surgery rate (CSR) is a critical index used to show that cataract blindness is being eliminated. It is considered to be tightly connected to social economic development; however, it is still extre...

    Authors: Mingming Zhu, Jianfeng Zhu, Lina Lu, Xiangui He, Rong Zhao and Haidong Zou
    Citation: BMC Ophthalmology 2014 14:3
  35. Poor health literacy is often a key cause of lack of or delayed uptake of health care services. The aim of this study was to assess the health literacy of common ocular diseases, namely cataract, glaucoma, nig...

    Authors: Mohan Krishna Shrestha, Christina W Guo, Nhukesh Maharjan, Reeta Gurung and Sanduk Ruit
    Citation: BMC Ophthalmology 2014 14:2
  36. This study examined the refractive and visual outcome of wavefront-optimized laser in situ keratomileusis (LASIK) in eyes with low myopia and compound myopic astigmatism ≤ 0.75 diopter (D).

    Authors: Toam Katz, Andreas Frings, Stephan J Linke, Gisbert Richard, Vasyl Druchkiv and Johannes Steinberg
    Citation: BMC Ophthalmology 2014 14:1
  37. A strong association exists between the use of tamsulosin and the occurance of intraoperative floppy iris syndrome. Several methods were advocated to overcome the progressive intraopertive miosis.

    Authors: János Hargitai, László Vezendi, Jørgen Vigstrup, Finn Eisgart, Søren Lundbye-Christensen, Bálint Hargitai and Henrik Vorum
    Citation: BMC Ophthalmology 2013 13:83
  38. Herein we report a case of bilateral anterior ischemic optic neuropathy (AION) showing histopathologic evidence of AL-amyloidosis of the temporal arteries. It is known that light-chain (AL) amyloidosis may rar...

    Authors: Alberto Neri, Pierangela Rubino, Claudio Macaluso and Stefano A Gandolfi
    Citation: BMC Ophthalmology 2013 13:82

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