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  1. We reported a rare case of indirect choroidal neovascularization (CNV) secondary to a posterior-segment intraocular foreign body (IOFB) that was not located in the area of direct injury but in the fovea. After...

    Authors: Yu-Shiuan Lin and Kai-Ling Peng
    Citation: BMC Ophthalmology 2020 20:161
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Ophthalmology 2020 20:177

  2. To investigate the long term surgical outcomes of cataract surgery in severe and end stage glaucoma patients with preoperative intraocular pressure less than 21 mmHg, and to detect the associated factors.

    Authors: Lin Fu, Yau Kei Chan, Junhua Li, Li Nie, Na Li and Weihua Pan
    Citation: BMC Ophthalmology 2020 20:160
    Content type: Research article Published on:

  7. China has been undergoing dramatic economic development, accompanied by increased education load on the young children. This study is to investigate the prevalence, type, severity, and associated risk factors ...

    Authors: Jianyong Wang, Qianqian Ellie Cheng, Xiaojin Fu, Ronghua Zhang, Jia Meng, Fang Gu, Juanjuan Li and Gui-shuang Ying
    Citation: BMC Ophthalmology 2020 20:155
    Content type: Research article Published on:

  8. To evaluate changes of microvascular network of macular and peripapillary regions and to provide a quantitative measurement of foveal avascular zone (FAZ) in unilateral BRVO patients.

    Authors: Lulu Chen, Mingzhen Yuan, Lu Sun, Yuelin Wang and Youxin Chen
    Citation: BMC Ophthalmology 2020 20:154
    Content type: Research article Published on:

  9. Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia and precursor to multiple myeloma. It has known ocular manifestations, but has not previously been shown to have an associat...

    Authors: Emily A. Eton, Gary Abrams, Naheed W. Khan and Abigail T. Fahim
    Citation: BMC Ophthalmology 2020 20:153
    Content type: Case report Published on:

  10. Myopic eyes are longer than nonmyopic eyes and have thinner choroids. The purpose of present study was to investigate whether a thinner subfoveal choroid at 11 years of age predicted axial eye elongation and m...

    Authors: Mathias Hvidtfelt Hansen, Line Kessel, Xiao Qiang Li, Anne Mette Skovgaard, Michael Larsen and Inger Christine Munch
    Citation: BMC Ophthalmology 2020 20:152
    Content type: Research article Published on:

  11. Bilateral and multiple Valsalva-related sub-internal limiting membrane (ILM) hemorrhages in a familial retinal arteriolar tortuosity (FRAT) patient is rare, and we treated this patient by both observation and ...

    Authors: Ting Chen, Hongmei Zheng, Yunyun Wang, Junyi Hu and Changzheng Chen
    Citation: BMC Ophthalmology 2020 20:151
    Content type: Case report Published on:

  12. The EVEREST II study reported superior polyp closure rates and visual outcomes using combination standard photodynamic therapy (PDT) with intravitreal ranibizumab in the treatment of polypoidal choroidal vascu...

    Authors: Wei Kiong Ngo, Wai Kitt Chee, Colin S. Tan and Tock Han Lim
    Citation: BMC Ophthalmology 2020 20:150
    Content type: Research article Published on:

  14. Axenfeld-Rieger syndrome (ARS) is a congenital disease with a series of developmental abnormalities, and no case of ARS with cataract and small cornea has been reported in previous studies. In the present repo...

    Authors: Yajuan Ma, Xingdi Wu, Shuang Ni, Xiang Chen, Suhong He and Wen Xu
    Citation: BMC Ophthalmology 2020 20:148
    Content type: Case report Published on:

  15. Healthy corneal epithelium acts as a barrier against damage to the deeper structures in the eye. Failure in the mechanisms of corneal epithelization can lead to persistent epithelial defects of the cornea (PED...

    Authors: Hyun Sik Moon, Lan Li, Hyeon Jeong Yoon, Yong Sok Ji and Kyung Chul Yoon
    Citation: BMC Ophthalmology 2020 20:147
    Content type: Research article Published on:

  16. The prevalence of myopia and associated risk factors among children in Chongqing has not yet been determined. This study investigated the prevalence of myopia and possible relationships between myopia and seve...

    Authors: Zhihao Xie, Yue Long, Jingxuan Wang, Qiaoqiao Li and Qiang Zhang
    Citation: BMC Ophthalmology 2020 20:146
    Content type: Research article Published on:

  18. Trachoma is a contagious infection of the eye. World Health Organization recommended three rounds of mass drug administration in districts where the prevalence of trachomatous follicular (TF) is ≥10% in childr...

    Authors: Gebremeskel Reda, Dejen Yemane and Aregawi Gebreyesus
    Citation: BMC Ophthalmology 2020 20:144
    Content type: Research article Published on:

  21. In order to detect glaucomatous optic nerve damages early on and evaluate the severity of glaucoma, a previously developed analytic method based on photographic retinal nerve fiber layer (RNFL) angle defect wa...

    Authors: Alexander Chen, Ing-Chou Lai, Wan-Hua Cho, Hung-Yin Lai, Pei-Wen Lin, Pei-Chang Wu and Ming-Tse Kuo
    Citation: BMC Ophthalmology 2020 20:141
    Content type: Research article Published on:

  24. Endogenous endophthalmitis is an infection of the eye secondary to sepsis, occurring in 0.04–0.5% of bacteremia or fungemia. Risk factors include intravenous drug abuse (IVDA), diabetes, indwelling catheters, ...

    Authors: Kathleen A. Regan, Nila S. Radhakrishnan, Jon D. Hammer, Benjamin D. Wilson, Lara Beth Gadkowski and Siva S. R. Iyer
    Citation: BMC Ophthalmology 2020 20:138
    Content type: Research article Published on:

  26. Limited data is available on retinal vessel morphology in the north China. The study aimed to evaluate the prevalence of retinal vascular abnormalities (RVAs) and investigate their associations with the self-r...

    Authors: Junwei Wang, Fei Leng, Zhijian Li, Xianling Tang, Hua Qian, Xiaoguang Li, Yi Zhang, Xuedong Chen, Haitao Du and Ping Liu
    Citation: BMC Ophthalmology 2020 20:136
    Content type: Research article Published on:

  28. Inflammation of RPE cells led to different kinds of eye diseases and affected the normal function of the retina. Furthermore, higher levels of ROCK1 and ROCK2 induced injury of endothelial cells and many infla...

    Authors: Zhao Gao, Qiang Li, Yunda Zhang, Xiaohong Gao, Haiyan Li and Zhigang Yuan
    Citation: BMC Ophthalmology 2020 20:134
    Content type: Research article Published on:

  29. Bullous serous retinal detachment (RD) with retinal pigment epithelial (RPE) tear is a rare and severe variant of chronic central serous chorioretinopathy (CSC). Due to its atypical presentation, it may raise ...

    Authors: Emilia Maggio, Maurizio Mete, Giorgia Maraone, Fabrizio Arena and Grazia Pertile
    Citation: BMC Ophthalmology 2020 20:133
    Content type: Case report Published on:

  30. Evidence-based criteria for the treatment of autoimmune retinopathy (AIR) have not been established. The pathology and clinical features of each antibody causing AIR, and its long-term course are still undeter...

    Authors: Gen Miura, Takayuki Baba, Takehito Iwase, Hisao Ohde, Atsuhiro Kanda, Wataru Saito, Susumu Ishida and Shuichi Yamamoto
    Citation: BMC Ophthalmology 2020 20:132
    Content type: Case report Published on:

  32. To compare efficacy and safety of intravitreal aflibercept (IVA) injection with panretinal photocoagulation (PRP) versus early vitrectomy for diabetic vitreous hemorrhage (VH).

    Authors: Ahmed Hosni Abd Elhamid, Ahmed Abd El Alim Mohamed and Abeer Mohamed Khattab
    Citation: BMC Ophthalmology 2020 20:130
    Content type: Research article Published on:

  33. We aimed to compare the intraocular pressure (IOP) measurements by a dynamic Scheimpflug analyzer (Corvis ST), a non-contact tonometer, and an ocular response analyzer after hyperopic small-incision lenticule ...

    Authors: Dan Fu, Meiyan Li, Michael C. Knorz, Shengsheng Wei, Jianmin Shang and Xingtao Zhou
    Citation: BMC Ophthalmology 2020 20:129
    Content type: Research article Published on:

  36. Group B streptococcus (GBS), a gram-positive coccus that occasionally causes neonatal sepsis or invasive infection in the elderly, has been considered a rare cause of endogenous bacterial endophthalmitis (EBE)...

    Authors: Masaaki Yoshida, Shunji Yokokura, Takashi Nishida, Kiyofumi Mochizuki, Takashi Suzuki, Kazuichi Maruyama, Takaaki Otomo, Koji M. Nishiguchi, Hiroshi Kunikata and Toru Nakazawa
    Citation: BMC Ophthalmology 2020 20:126
    Content type: Research article Published on:

  37. Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uv...

    Authors: Aline C. Stolk-Vos, Hamasa Kasigar, Karlijn J. Nijmeijer, Tom O. Missotten, Jan J. Busschbach, Joris J. van de Klundert and Leonieke W. Kranenburg
    Citation: BMC Ophthalmology 2020 20:125
    Content type: Research article Published on:

  38. Eye infection is a public health problem in developing countries including Ethiopia. Bacteria are major causative agents of eye infections that can lead to loss of vision. The objective of this study was to de...

    Authors: Ahmed Adem Mohammed, Musa Mohammed Ali and Mengistu Hailemariam Zenebe
    Citation: BMC Ophthalmology 2020 20:124
    Content type: Research article Published on:

  39. Several previous studies reported a greater prevalence of dry eye syndrome (DES) among patients with psychiatric diseases. The aim of this study is to investigate the prevalence and risk factors of DES in pati...

    Authors: Chiao-Ying Liang, Wai-Man Cheang, Chun-Yuan Wang, Keng-Hung Lin, Li-Chen Wei, Yu-Yen Chen and Ying-Cheng Shen
    Citation: BMC Ophthalmology 2020 20:123
    Content type: Research article Published on:

  40. Intravitreal injections are a mandatory treatment for macular edema due to nAMD, DME and RVO. These chronic diseases usually need chronic treatment using intravitreal injections with anti-VEGF agents. Thus, ma...

    Authors: Ingo Volkmann, Katharina Knoll, Mareile Wiezorrek, Oliver Greb and Carsten Framme
    Citation: BMC Ophthalmology 2020 20:122
    Content type: Research article Published on:

  41. Pupillary evaluation is a crucial element of physical exams. Noting size, reactivity, and consensual response is critical in assessing for optic nerve dysfunction. We aim to establish normative data for scotop...

    Authors: Sanket S. Shah, Hantamalala Ralay Ranaivo, Rebecca B. Mets-Halgrimson, Karen Rychlik and Sudhi P. Kurup
    Citation: BMC Ophthalmology 2020 20:121
    Content type: Research article Published on:

  42. The cellular process of autophagy is essential for maintaining the health of ocular tissue. Dysregulation of autophagy is associated with several ocular diseases including keratoconus and macular degeneration....

    Authors: Kimberly M. Brothers, Nicholas A. Stella and Robert M. Q. Shanks
    Citation: BMC Ophthalmology 2020 20:120
    Content type: Research article Published on:

  43. Age-related macular degeneration (AMD) represents the leading cause of visual impairment in the aging population. The goal of this study was to identify aberrantly-methylated, differentially-expressed genes (M...

    Authors: Yinchen Shen, Mo Li, Kun Liu, Xiaoyin Xu, Shaopin Zhu, Ning Wang, Wenke Guo, Qianqian Zhao, Ping Lu, Fudong Yu and Xun Xu
    Citation: BMC Ophthalmology 2020 20:119
    Content type: Research article Published on:

  44. Peters plus syndrome (PPS) is a combination of congenital Peters anomaly and systemic abnormalities. It is inherited most commonly in an autosomal recessive pattern with homozygous B3GLCT mutations. Ocular findin...

    Authors: Ye Elaine Wang, Dhariana Acon Ramirez, Ta Chen Chang and Audina Berrocal
    Citation: BMC Ophthalmology 2020 20:118
    Content type: Case report Published on:

  45. A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surge...

    Authors: Henry Bair, Chun-Ju Lin, Chun-Ting Lai, Ning-Yi Hsia and Yi-Yu Tsai
    Citation: BMC Ophthalmology 2020 20:117
    Content type: Case report Published on:

  46. To evaluate the feasibility of a surgical technique using a sub-perfluoro-n-octane (PFO) injection of ocular viscoelastic device (OVD) to stabilize inverted internal limiting membrane (ILM) flap for the treatm...

    Authors: Chi-Chun Lai, An-Lun Wu, Hung-Da Chou, Wee Min Teh, Kuan-Jen Chen, Yen-Po Chen, Laura Liu, Yih-Shiou Hwang and Wei-Chi Wu
    Citation: BMC Ophthalmology 2020 20:116
    Content type: Research article Published on:

  47. This study aimed to evaluate the visual and morphological outcomes of intravitreal anti-VEGF therapy and the recurrence for idiopathic choroidal neovascularization (ICNV).

    Authors: Qianru Wu, Xiaoyong Chen, Kang Feng, Yuling Liu, Chun Zhang and Lin Zhao
    Citation: BMC Ophthalmology 2020 20:115
    Content type: Research article Published on:

  48. Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagno...

    Authors: Takumasa Tsuji, Yuta Hirose, Kohei Fujimori, Takuya Hirose, Asuka Oyama, Yusuke Saikawa, Tatsuya Mimura, Kenshiro Shiraishi, Takenori Kobayashi, Atsushi Mizota and Jun’ichi Kotoku
    Citation: BMC Ophthalmology 2020 20:114
    Content type: Research article Published on:

  49. Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this c...

    Authors: Mingyue Luo, Zhe Chen, Yaping Luo, Lin Zhao, Rongping Dai and Yong Zhong
    Citation: BMC Ophthalmology 2020 20:113
    Content type: Case report Published on:

  50. In this case presentation, we present a young vegan patient who developed a CRVO secondary to severe iron-deficiency anaemia (IDA) attributable to menstrual losses and limited iron intake. CRVO is a rare compl...

    Authors: Verlyn Yang, Liam Daniel Turner and Fraser Imrie
    Citation: BMC Ophthalmology 2020 20:112
    Content type: Case report Published on:
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