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  1. To evaluate the efficacy of the topical administration of immunosuppressants and corticosteroids in tapering doses in the management of patients with high-risk keratoplasty.

    Authors: Xiaolin Qi, Lichao Wang, Xiaoyu Zhang, Min Liu and Hua Gao
    Citation: BMC Ophthalmology 2022 22:101
    Content type: Research article Published on:

  3. Graft-versus-host disease (GVHD) is the most common complication after bone marrow allogeneic hematopoietic stem cell transplantation (allo-HSCT). The incidence of posterior segment complications was significa...

    Authors: Bowen Wang, Fagang Jiang and Xinghua Wang
    Citation: BMC Ophthalmology 2022 22:97
    Content type: Case report Published on:

  6. To assess whether insulin therapy impacts the effectiveness of anti-vascular endothelial growth factor (anti-VEGF) injection for the treatment of diabetic macular edema (DME) in type 2 diabetes mellitus.

    Authors: Rajya L. Gurung, Liesel M. FitzGerald, Ebony Liu, Bennet J. McComish, Georgia Kaidonis, Bronwyn Ridge, Alex W. Hewitt, Brendan JT. Vote, Nitin Verma, Jamie E. Craig and Kathryn P. Burdon
    Citation: BMC Ophthalmology 2022 22:94
    Content type: Research Published on:

  8. To evaluate retinal hard exudates (HEs) progression in patients with cystoid macular edema (CME) secondary to diabetic retinopathy (DR) or branch retinal vascular occlusion (BRVO) after intravitreal injections...

    Authors: Rui Shi, Zhonglan Guo, Xiangxiang Yang and Xuanyi Che
    Citation: BMC Ophthalmology 2022 22:92
    Content type: Research Published on:

  9. We report a case of bilateral pachychoroid disease with type 3 uveal effusion syndrome (UES) in one eye and central serous chorioretinopathy (CSC) in the contralateral eye.

    Authors: Hajime Onoe, Hiroyuki Shimada, Akiyuki Kawamura, Hiromi Hirosawa, Koji Tanaka, Ryusaburo Mori and Hiroyuki Nakashizuka
    Citation: BMC Ophthalmology 2022 22:91
    Content type: Case report Published on:

  10. Patients with psoriatic arthritis (PsA) may develop uveitis, a potentially serious ocular complication. PsA-related uveitis may result in significant morbidity and even vision loss if underdiagnosed or under-t...

    Authors: Po-Ying Wu, Chia-Chen Kao and Shwu-Jiuan Sheu
    Citation: BMC Ophthalmology 2022 22:90
    Content type: Case report Published on:

  12. Pigment epithelial-derived factor (PEDF), a 50 kDa secreted glycoprotein, exhibits distinct effects on a range of cell types. PEDF has been shown to inhibit vascular endothelial growth factor (VEGF)-mediated a...

    Authors: Tsung-Chuan Ho, Shu-I Yeh, Show-Li Chen, Ting-Wen Chu and Yeou-Ping Tsao
    Citation: BMC Ophthalmology 2022 22:88
    Content type: Research Published on:

  13. Scleral cross-linking can enhance the biomechanical strength of the sclera and is expected to be a new operative method for the prevention of myopia. However, studies investigating the changes in intraocular p...

    Authors: Chong Liu, Yu Li, Mengmeng Wang, Jing Li, Ningli Wang and Fengju Zhang
    Citation: BMC Ophthalmology 2022 22:87
    Content type: Research article Published on:

  14. Diabetes mellitus (DM) is a complex metabolic syndrome characterized by hyperglycemia. Diabetic retinopathy (DR) is the most common complication of DM and the leading cause of blindness in the working-age popu...

    Authors: Xinran Qin and Haidong Zou
    Citation: BMC Ophthalmology 2022 22:86
    Content type: Review Published on:

  18. To assess postoperative changes in angle alpha, and to evaluate the postoperative visual quality of patients with different angle alpha values after implantation of extended depth of focus (EDOF) intraocular l...

    Authors: Miaomiao Qin, Min Ji, Tianqiu Zhou, Yurong Yuan, Jiawei Luo, Pengfei Li, Ying Wang, Xiaojuan Chen, Wei Chen and Huaijin Guan
    Citation: BMC Ophthalmology 2022 22:82
    Content type: Research Published on:

  19. A simple technique to facilitate removal of subincisional cortex in cataract surgery is presented.

    Authors: Teruyuki Miyoshi, Hironori Yoshida, Takahiro Shimowake and Tetsuro Oshika
    Citation: BMC Ophthalmology 2022 22:81
    Content type: Research Published on:

  21. The purpose of this study is to describe measurements using a newly developed modified Goldmann convex tonometer (CT) 1 year after myopic laser refractive surgery. Intraocular pressure (IOP) measurements were ...

    Authors: María Iglesias, Bachar Kudsieh, Andrea Laiseca, Cristina Santos, Jeroni Nadal, Rafael Barraquer and Ricardo P. Casaroli-Marano
    Citation: BMC Ophthalmology 2022 22:79
    Content type: Research Published on:

  23. To assess the microvascular changes in the macular region and the foveal avascular zone (FAZ) area in participants with white matter hyperintensities (WMHs) using swept source optical coherence tomography angi...

    Authors: Yuzhu Gao, William Robert Kwapong, Yifan Zhang, Yuying Yan, Xurui Jin, Yunhan Tao, Hanyue Xu, Bo Wu and Ming Zhang
    Citation: BMC Ophthalmology 2022 22:77
    Content type: Research Published on:

  26. Formulas predicting intraocular lens power have not been compared in silicone oil-tamponaded eyes. The study aims to compare six intraocular lens power assessment formulas in silicone oil-tamponaded eyes.

    Authors: Yanan Hou, Lei Liu, Gang Wang, Junwei Xie and Yi Wang
    Citation: BMC Ophthalmology 2022 22:74
    Content type: Research Published on:

  28. β-Zone parapapillary atrophy (β-PPA) is a common sign in patients with open-angle glaucoma (OAG). Some studies have suggested that β-PPA can aid in the diagnosis of OAG. We performed a systematic review and me...

    Authors: Dengming Zhou, Mengdan Cao and Xuanchu Duan
    Citation: BMC Ophthalmology 2022 22:72
    Content type: Research article Published on:

  30. Congenital cataract-microcornea syndrome (CCMC) is characterized by the association of congenital cataract and microcornea without any other systemic anomaly or dysmorphism. Although several causative genes ha...

    Authors: Zhi-Bo Lin, Jin Li, Lu Ye, Hai-Sen Sun, A-Yong Yu, Shi-Hao Chen and Fen-Fen Li
    Citation: BMC Ophthalmology 2022 22:70
    Content type: Research Published on:

  32. To assess transepithelial photorefractive keratectomy (tPRK) in terms of corneal epithelial healing rate, postoperative pain, postoperative discomfort, and visual and refraction outcomes compared to mechanical...

    Authors: Hassan Hashemi, Azam Alvani, Mohammadreza Aghamirsalim, Mohammad Miraftab and Soheila Asgari
    Citation: BMC Ophthalmology 2022 22:68
    Content type: Research article Published on:

  33. Human umbilical cord mesenchymal stem cells (UCMSCs) transplantation is a promising therapy for the treatment of retinitis pigmentosa (RP). However, intravenously infused cells may be blocked in the lung, incr...

    Authors: Qingling Liang, Qiyou Li, Bangqi Ren and Zheng Qin Yin
    Citation: BMC Ophthalmology 2022 22:67
    Content type: Research Published on:

  34. Studies on the factors related to lacrimal gland prolapse (LGP) in patients with thyroid-associated ophthalmopathy (TAO) are limited. This study aimed to assess the factors associated with LGP on magnetic reso...

    Authors: Yang Gao, Qinglin Chang, Yang Li, Hanqiao Zhang, Zhijia Hou, Zheng Zhang, Zheng Li and Dongmei Li
    Citation: BMC Ophthalmology 2022 22:66
    Content type: Research Published on:

  36. In clinical practice, fluctuating vision or decreased quality of vision is a common complaint in DED patients. Our study was designed to investigate the change in dynamic optical quality in dry eye patients af...

    Authors: Zhenyu Wei, Yuandong Su, Guanyu Su, Christophe Baudouin, Antoine Labbé and Qingfeng Liang
    Citation: BMC Ophthalmology 2022 22:64
    Content type: Research article Published on:

  37. Intravitreal injection of anti-vascular endothelial growth factor (VEGF) has become first line therapy for diabetic macular edema. This study evaluated the efficacy and safety of intravitreal injection of Rani...

    Authors: Shengguo Li, Yan Yang, Jingling Zou, Jun Zeng and Chun Ding
    Citation: BMC Ophthalmology 2022 22:63
    Content type: Research Published on:

  42. To determine the effect of sodium hyaluronate combined with recombinant human epidermal growth factor (rhEGF) on clinical symptoms and inflammation in patients with newly diagnosed xerophthalmia after cataract...

    Authors: Xuewu Gong, Hongbo Yao and Jing Wu
    Citation: BMC Ophthalmology 2022 22:58
    Content type: Research article Published on:

  43. While each scleral fixation method has its own advantages, there is a lack of strong evidence to suggest a superior technique. Advances in cataract surgery expand patient eligibility for successful cataract ex...

    Authors: Mariya Zyablitskaya, Estee Hong, Royce W. S. Chen, Stanley Chang and Leejee H. Suh
    Citation: BMC Ophthalmology 2022 22:57
    Content type: Research Published on:

  44. Spectral domain optical coherence tomography (SD-OCT) is a widely applied non-invasive technique for evaluating optic nerve head parameters. The aim of this study was to evaluate the impact of biometric parame...

    Authors: E. Elksne, J. V. Stingl, A. K. Schuster, F. M. Wagner and E. M. Hoffmann
    Citation: BMC Ophthalmology 2022 22:56
    Content type: Research article Published on:

  45. Our purpose was to describe a patient who developed combined central retinal vein occlusion (CRVO), cilioretinal artery occlusion, branch retinal artery occlusion (BRAO), and anterior ischaemic optic neuropath...

    Authors: Anis Mahmoud, Molka Khairallah, Hassen Ibn Hadj Amor, Mohamed Habib Lahdhiri, Nesrine Abroug, Riadh Messaoud and Moncef Khairallah
    Citation: BMC Ophthalmology 2022 22:55
    Content type: Case report Published on:

  46. Metrics derived from the human eye are increasingly used as biomarkers and endpoints in studies of cardiovascular, cerebrovascular and neurological disease. In this context, it is important to account for pote...

    Authors: Stewart J. Wiseman, Andrew J. Tatham, Rozanna Meijboom, Graciela Muniz Terrera, Charlene Hamid, Fergus N. Doubal, Joanna M. Wardlaw, Craig Ritchie, Baljean Dhillon and Tom MacGillivray
    Citation: BMC Ophthalmology 2022 22:54
    Content type: Research Published on:

  48. Visual impairment is a functional limitation of the eye(s) that results in reduced visual acuity, visual field loss, visual distortion, perceptual difficulties, or any combination of the above. Type 2 diabetes...

    Authors: Mohammed Abdu Seid, Adugnaw Ambelu, Mengistie Diress, Yigizie Yeshaw, Yonas Akalu and Baye Dagnew
    Citation: BMC Ophthalmology 2022 22:52
    Content type: Research Published on:

  49. Branch retinal vein occlusion (BRVO) is one of the most important causes of visual loss in retinal vascular diseases. The aim of this study is to predict the treatment response of anti-vascular endothelial gro...

    Authors: Pei-Wei Huang, Chi-Chun Lai, Yih-Shiou Hwang, Wei-Chi Wu, Cheng-Hsiu Wu, Jerry Chien-Chieh Huang, Yen-Po Chen, Laura Liu, Kuan-Jen Chen and Ling Yeung
    Citation: BMC Ophthalmology 2022 22:50
    Content type: Research Published on:

  50. Human herpesvirus 6B (HHV-6B) is known to cause exanthema subitem and has been detected in various ocular diseases, including keratitis, uveitis, optic neuritis, and endophthalmitis; however, the long-term out...

    Authors: Takashi Ono, Takuya Iwasaki, Yukiko Terada, Yosai Mori, Ryohei Nejima, Mineo Ozaki, Manabu Mochizuki and Kazunori Miyata
    Citation: BMC Ophthalmology 2022 22:48
    Content type: Case report Published on:
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