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  1. Visual fixation may be affected in amblyopic patients and, moreover, its stability may be associated with the effects of amblyopic treatments on visual performance in patients with strabismus. Therefore, fixat...

    Authors: Otto Alexander Maneschg, Mirella Telles Salgueiro Barboni, Zoltán Zsolt Nagy and János Németh

    Citation: BMC Ophthalmology 2021 21:264

    Content type: Research

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  3. Glaucomatous eyes often show strong intraocular pressure (IOP) fluctuations and individual measurements at different time points are necessary for personalized therapy. To survey IOP variations 48-hours diurna...

    Authors: Marion Zimmermann, Bert C. Giers, Anna Beck, Katharina Bell, Herwig Zimmermann, Marlene Hechtner, Esther M. Hoffmann, Norbert Pfeiffer and Katrin Lorenz

    Citation: BMC Ophthalmology 2021 21:262

    Content type: Research article

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  4. To evaluate microstructural changes in the meibomian glands (MGs) in patients with active and inactive Graves’ orbitopathy (GO), using in vivo confocal microscopy (IVCM), and to investigate the correlations be...

    Authors: Shengnan Cheng, Yueqi Yu, Jin Chen, Lin Ye, Xinghua Wang and Fagang Jiang

    Citation: BMC Ophthalmology 2021 21:261

    Content type: Research article

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  5. Our study aimed to explore the prevalence and risk factors of refractive error (RE) in Han and Tibetan population aged 50–79 years in Xining and surrounding areas in Qinghai Province on Qinghai-Tibet Plateau.

    Authors: Meng Wang, Linyang Gan, Jiantao Cui, Guangliang Shan, Ting Chen, Xianghua Wang, Yuhan Wang, Li Pan, Zhanquan Li, Sen Cui, Airong Yang, Wenfang Li, Guoqiang Jia, Ximing Han, Huijing He, Yong Zhong…

    Citation: BMC Ophthalmology 2021 21:260

    Content type: Research

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  6. Diabetic retinopathy is the most common microvascular complication of diabetes; however, early changes in retinal microvessels are difficult to detect clinically, and a patient’s vision may have begun to deter...

    Authors: Xinyue Li, Yu Yu, Xueting Liu, Yan Shi, Xin Jin, Yanyan Zhang, Shuo Xu, Nan Zhang, Li Dong, Sujun Zhou, Yingbin Wang, Yiheng Ding, Zhen Song and Hong Zhang

    Citation: BMC Ophthalmology 2021 21:259

    Content type: Research

    Published on:

  7. During the coronavirus disease 2019 (COVID-19) epidemic, due to the traffic blockade and the shortage of medical resources, more and more premature infants could not receive timely and effective ROP screening,...

    Authors: Zheng Guo, Nan Ma, Yixuan Wu, Hua Yuan, Wanjun Luo, Lingkong Zeng, Hong Jie and Shilian Li

    Citation: BMC Ophthalmology 2021 21:258

    Content type: Research

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  9. To evaluate the necessity of cycloplegia for epidemiological studies of refraction in Chinese young adults (aged 17–22 years) with dark irises, and to compare the cycloplegic effects of 1% cyclopentolate and 0...

    Authors: Ruxia Pei, Zhuzhu Liu, Hua Rong, Liqiong Zhao, Bei Du, Na Jin, Hongmei Zhang, Biying Wang, Yi Pang and Ruihua Wei

    Citation: BMC Ophthalmology 2021 21:256

    Content type: Research article

    Published on:

  10. Previous studies have demonstrated that strabismus amblyopia can result in markedly brain function alterations. However, the differences in spontaneous brain activities of strabismus amblyopia (SA) patients st...

    Authors: Shuang Zhang, Gui-Ping Gao, Wen-Qing Shi, Biao Li, Qi Lin, Hui-Ye Shu and Yi Shao

    Citation: BMC Ophthalmology 2021 21:255

    Content type: Research

    Published on:

  13. To describe the longitudinal changes in retinal neovascularization elsewhere (NVE) as observed on optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR) treated by panretin...

    Authors: H. E. Feng, Y. U. Weihong and Fangtian Dong

    Citation: BMC Ophthalmology 2021 21:252

    Content type: Research

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  15. The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymo...

    Authors: Ine Lambert, Giuseppe Fasolino, Gil Awada, Robert Kuijpers, Marcel ten Tusscher and Bart Neyns

    Citation: BMC Ophthalmology 2021 21:250

    Content type: Case report

    Published on:

  16. ALG3-CDG is a rare autosomal recessive disease. It is characterized by deficiency of alpha-1,3-mannosyltransferase caused by pathogenic variants in the ALG3 gene. Patients manifest with severe neurologic, cardiac...

    Authors: Martina Farolfi, Anna Cechova, Nina Ondruskova, Jana Zidkova, Bohdan Kousal, Hana Hansikova, Tomas Honzik and Petra Liskova

    Citation: BMC Ophthalmology 2021 21:249

    Content type: Research

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  17. Eye injury is a serious worldwide public health problem that may cause blindness. In children, blindness has functional impact and psychosocial implications. As indicated in many worldwide studies, identificat...

    Authors: Valeria D’Antone, Diana Cristina Palencia Flórez, Claudia Juliana Lopez García, Flor De María Cáceres Manrique and Nahyr López Barbosa

    Citation: BMC Ophthalmology 2021 21:248

    Content type: Research

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  20. We aimed to evaluate the efficacy and safety of phacoemulsification with intravitreal 3 mg triamcinolone acetonide injection in preventing postoperative inflammation and complications in patients with non-infe...

    Authors: Yan Ren, Shufang Du, Dongping Zheng, Yanyun Shi, Luping Pan and Hua Yan

    Citation: BMC Ophthalmology 2021 21:245

    Content type: Research

    Published on:

  22. To evaluate alterations in the serum concentrations of vascular endothelial growth factor (VEGF) and netrin-1 after intravitreal bevacizumab (BCZ) injection for the treatment of diabetic macular edema (DME).

    Authors: Murat Okutucu, Hüseyin Fındık, Mehmet Gökhan Aslan and Medeni Arpa

    Citation: BMC Ophthalmology 2021 21:243

    Content type: Research

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  23. Choroidal osteoma is a benign intraocular tumor that can increase risk of developing choroidal neovascularization. The visual prognosis is influenced by the tumor location, decalcification status, overlying RP...

    Authors: Yun Zhang, Jia Fang, Shixin Zhao, Xiangjun She, Jun Wang and Lijun Shen

    Citation: BMC Ophthalmology 2021 21:242

    Content type: Case report

    Published on:

  24. The effect of various reduced doses of verteporfin photodynamic therapy (PDT) on choroidal blood flow in chronic central serous chorioretinopathy (CSC) remains unclear. Therefore, this study aimed to evaluate ...

    Authors: Shun Kumashiro, Seiji Takagi, Takashi Itokawa, Akiko Tajima, Tatsuhiko Kobayashi and Yuichi Hori

    Citation: BMC Ophthalmology 2021 21:241

    Content type: Research

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  25. Myotonic dystrophy is an inherited disease characterized by progressive muscle weakness and myotonia. It is a multisystemic disorder that affects different parts of the body, including the eye. Dysfunction of ...

    Authors: Eric Kirkegaard-Biosca, Mònica Berges-Marti, Brahim Azarfane, Esther Cilveti, Laura Distefano and Jose García-Arumí

    Citation: BMC Ophthalmology 2021 21:240

    Content type: Case report

    Published on:

  26. Bietti crystalline dystrophy (BCD) is an autosomal recessive genetic disorder that causes progressive vision loss. Here, 12 patients were followed up for 1–5 years with fundus fluorescein angiography (FFA) to ...

    Authors: Shengjuan Zhang, Lifei Wang, Zhiqiang Liu, Huijing Sun, Qian Li, Chen Xing, Zhe Xiao and Xiaoyan Peng

    Citation: BMC Ophthalmology 2021 21:239

    Content type: Research article

    Published on:

  27. To compare quantitative visual tests, such as visual acuity, contrast sensitivity, and color vision tests in patients with primary open-angle glaucoma (POAG) patients according to three different light systems...

    Authors: Sang Woo Kim, YoungWook Go, Sang-Ook Kang and Chang Kyu Lee

    Citation: BMC Ophthalmology 2021 21:238

    Content type: Research

    Published on:

  29. We aimed to validate the predictive performance of the DIGIROP-Birth model for identifying treatment-requiring retinopathy of prematurity (TR-ROP) in Chinese preterm infants to evaluate its generalizability ac...

    Authors: Sizhe Chen, Rong Wu, He Chen, Wenbei Ma, Shaolin Du, Chao Li, Xiaohe Lu and Songfu Feng

    Citation: BMC Ophthalmology 2021 21:236

    Content type: Research

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  30. Recently, we found that maximal medial rectus recession and lateral rectus resection in patients with complete lateral rectus paralysis resulted in a partial restoration of abduction. In an attempt to understa...

    Authors: Qing Xia, Xiangtian Ling, Zhonghao Wang, Tao Shen, Minghao Chen, Danyi Mao, Xinqi Ma, Jie Ning, Han Zhang, Dongli Chen, Qiong Gu, Huangxuan Shen and Jianhua Yan

    Citation: BMC Ophthalmology 2021 21:235

    Content type: Research

    Published on:

  32. This study aims to evaluate choroidal thickness (CT), retinal thickness, ganglion cell-inner plexiform layer (GCIPL), and retinal nerve fiber layer (RNFL) structures in psoriasis patients using optical coheren...

    Authors: Asena Keles Sahin, Fatma Etgü and Aslihan Uzun

    Citation: BMC Ophthalmology 2021 21:233

    Content type: Research

    Published on:

  34. Intraocular lens (IOL) calculation using traditional formulas for post-corneal refractive surgery eyes can yield inaccurate results. This study aimed to compare the clinical accuracy of the newly developed Zha...

    Authors: Jun Zhang, Jie Shao, Li Zheng, Ye Shen and Xia Zhao

    Citation: BMC Ophthalmology 2021 21:231

    Content type: Research

    Published on:

  37. Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we e...

    Authors: William Greig Mitchell, Edward Christopher Dee and Leo Anthony Celi

    Citation: BMC Ophthalmology 2021 21:228

    Content type: Correspondence

    Published on:

  39. Glaucoma is a leading cause of global blindness, especially preventable blindness. The increased prevalence of glaucoma has led to a growing demand for newer, safer, more rapid, and simpler treatments for the ...

    Authors: Noa Kapelushnik, Ari Leshno, Reut Singer, Ruth Huna-Baron, Yaniv Barkana and Alon Skaat

    Citation: BMC Ophthalmology 2021 21:226

    Content type: Research

    Published on:

  41. Filamentous fungi are ubiquitous in plants, water, and soil. The predominant fungi that infect the human cornea include Fusarium and Aspergillus species. The onset of fungal endophthalmitis is indolent, and typic...

    Authors: Yusuke Mitsuoka, Takeshi Soma, Kazuichi Maruyama and Kohji Nishida

    Citation: BMC Ophthalmology 2021 21:224

    Content type: Case report

    Published on:

  42. Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical co...

    Authors: Santiago Delgado-Tirado, Alberto López-Miguel, Yazmin Báez-Peralta, Lucía González-Buendía, Itziar Fernández, Jorge L. Alió, Miguel J. Maldonado and Rosa M. Coco-Martín

    Citation: BMC Ophthalmology 2021 21:223

    Content type: Research

    Published on:

  45. To investigate the changes in retinal nerve fiber layer thickness and macular blood flow density during the preclinical stage of diabetic retinopathy and their relationship with blood glucose.

    Authors: Hui Li, Xiaobing Yu, Bodi Zheng, Shan Ding, Zhongqing Mu and Lixin Guo

    Citation: BMC Ophthalmology 2021 21:220

    Content type: Research article

    Published on:

  46. The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients’ quality of life. No published studies on the epidemiology of dry eyes hav...

    Authors: Sarah Alkabbani, Lakshmanan Jeyaseelan, Anupama P. Rao, Sandeep P. Thakur and Pramod T. Warhekar

    Citation: BMC Ophthalmology 2021 21:219

    Content type: Research

    Published on:

  47. Insulin positively correlates with the length of the eye axis and is increased in the vitreous and serum of patients with pathological myopia (PM). How insulin influences the physiological process of retinal p...

    Authors: Yunqin Li, Junliang Jiang, Jin Yang, Libo Xiao, Qiyun Hua and Yue Zou

    Citation: BMC Ophthalmology 2021 21:218

    Content type: Research article

    Published on:

  49. The refractive surgeries induce corneal higher order aberrations (C-HOAs). In this study, change of C-HOAs after small-incision lenticule extraction (SMILE) compared to femtosecond assisted laser in situ kerat...

    Authors: Mohammad Miraftab, Hassan Hashemi, Mohammadreza Aghamirsalim, Shiva Fayyaz and Soheila Asgari

    Citation: BMC Ophthalmology 2021 21:216

    Content type: Research

    Published on:

  50. The COVID-19 Pandemic has a great impact on hospitals and patients. The 14-day quarantine caused surgery of rhegmatogenous retinal detachment (RRD) postponed. We aimed to explore the risk factors of RRD progre...

    Authors: Meng Zhao, Jipeng Li, Haicheng She and Ningpu Liu

    Citation: BMC Ophthalmology 2021 21:215

    Content type: Research

    Published on:

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BMC Ophthalmology

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